William F Elmquist

Professor, Pharmaceutics

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Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

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4 Active
12 Finished

Intrathecal delivery of radiation sensitizing nanoparticles in pediatric neuro-oncology
Elmquist, W. F.
U OF TX HEALTH SCIENCE CTR. AT HOUSTON
8/2/19 → 6/30/24
Project: Research project
A novel strategy to overcome the P-gp/BCRP drug efflux system at the blood-brain barrier to improve brain uptake of CNS therapeutics
Elmquist, W. F.
University of Kentucky
8/15/18 → 7/31/21
Project: Research project
Pre-Clinical Novel Radiosensitizer Evaluation Program fo
Elmquist, W. F.
Mayo Clinic
6/14/18 → 5/31/21
Project: Research project
MIT/Mayo Physical Sciences Center for Drug Delivery and
Elmquist, W. F.
Massachusetts Institute of Technology
8/29/16 → 7/31/21
Project: Research project
Targeting Kif11 to Treat Glioblastoma Invasion and Proli
Elmquist, W. F.
MAYO CLINIC - JACKSONVILLE
7/1/17 → 12/31/20
Project: Research project

92 Article
11 Review article
5 Comment/debate
2 Chapter
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Baseline requirements for novel agents being considered for phase II/III brain cancer efficacy trials: Conclusions from the Adult Brain Tumor Consortium's first workshop on CNS drug delivery
Grossman, S. A., Romo, C. G., Rudek, M. A., Supko, J., Fisher, J., Burt Nabors, L., Wen, P. Y., Peereboom, D. M., Ellingson, B. M., Elmquist, W., Barker, F. G., Kamson, D., Sarkaria, J. N., Timmer, W., Bindra, R. S. & Ye, X., Oct 1 2020, In: Neuro-Oncology. 22, 10, p. 1422-1424 3 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Comments on: “Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity”
van Tellingen, O., de Gooijer, M. C., Sarkaria, J. N. & Elmquist, W. F., Sep 1 2020, In: Neuro-Oncology. 22, 9, p. 1404-1405 2 p.
Research output: Contribution to journal › Letter › peer-review
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma
Gampa, G., Kenchappa, R. S., Mohammad, A. S., Parrish, K. E., Kim, M., Crish, J. F., Luu, A., West, R., Hinojosa, A. Q., Sarkaria, J. N., Rosenfeld, S. S. & Elmquist, W. F., Dec 1 2020, In: Scientific reports. 10, 1, 6524.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
High-dose MTX110 (soluble panobinostat) safely administered into the fourth ventricle in a nonhuman primate model
Sandberg, D. I., Kharas, N., Yu, B., Janssen, C. F., Trimble, A., Ballester, L. Y., Patel, R., Mohammad, A. S., Elmquist, W. F. & Sirianni, R. W., Aug 2020, In: Journal of Neurosurgery: Pediatrics. 26, 2, p. 127-135 9 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Localized metabolomic gradients in patient-derived xenograft models of glioblastoma
Randall, E. C., Lopez, B. G. C., Peng, S., Regan, M. S., Abdelmoula, W. M., Basu, S. S., Santagata, S., Yoon, H., Haigis, M. C., Agar, J. N., Tran, N. L., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., Mar 15 2020, In: Cancer Research. 80, 6, p. 1258-1267 10 p.
Research output: Contribution to journal › Article › peer-review
5 Scopus citations