William F Elmquist

1984 …2024

Research output per year

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Projects

Research Output

Brain distributional kinetics of a novel MDM2 inhibitor SAR405838: Implications for use in brain tumor therapy

Kim, M., Laramy, J. K., Gampa, G., Parrish, K. E., Brundage, R., Sarkaria, J. N. & Elmquist, W. F., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 12, p. 1403-1414 12 p.

Research output: Contribution to journalArticle

  • Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases

    Gampa, G., Kim, M., Mohammad, A. S., Parrish, K. E., Mladek, A. C., Sarkaria, J. N. & Elmquist, W. F., Mar 1 2019, In : The Journal of pharmacology and experimental therapeutics. 368, 3, p. 446-461 16 p.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Brain distribution of a panel of epidermal growth factor receptor inhibitors using cassette dosing in wild-type and ABCB1/ABCG2-deficient mice

    Kim, M., Laramy, J. K., Mohammad, A. S., Talele, S., Fisher, J., Sarkaria, J. N. & Elmquist, W. F., Apr 2019, In : Drug Metabolism and Disposition. 47, 4, p. 393-404 12 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases

    Babiker, H. M., Byron, S. A., Hendricks, W. P. D., Elmquist, W. F., Gampa, G., Vondrak, J., Aldrich, J., Cuyugan, L., Adkins, J., De Luca, V., Tibes, R., Borad, M. J., Marceau, K., Myers, T. J., Paradiso, L. J., Liang, W. S., Korn, R. L., Cridebring, D., Von Hoff, D. D., Carpten, J. D. & 3 others, Craig, D. W., Trent, J. M. & Gordon, M. S., Aug 15 2019, In : Investigational New Drugs. 37, 4, p. 636-645 10 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Barriers to Effective Drug Treatment for Brain Metastases: A Multifactorial Problem in the Delivery of Precision Medicine

    Kim, M., Kizilbash, S. H., Laramy, J. K., Gampa, G., Parrish, K. E., Sarkaria, J. N. & Elmquist, W. F., Sep 1 2018, In : Pharmaceutical research. 35, 9, 177.

    Research output: Contribution to journalReview article

  • 6 Scopus citations