Projects per year
Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
- 1 Similar Profiles
Brain
Medicine & Life Sciences
P-Glycoprotein
Medicine & Life Sciences
Blood-Brain Barrier
Medicine & Life Sciences
Microdialysis
Medicine & Life Sciences
Glioblastoma
Medicine & Life Sciences
Pharmaceutical Preparations
Medicine & Life Sciences
Breast Neoplasms
Medicine & Life Sciences
Pharmacokinetics
Medicine & Life Sciences
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Projects 1984 2020
A novel strategy to overcome the P-gp/BCRP drug efflux system at the blood-brain barrier to improve brain uptake of CNS therapeutics
8/15/18 → 7/31/20
Project: Research project
Blood-Brain Barrier
Brain
Pharmaceutical Preparations
Therapeutics
Program Evaluation
Brain Neoplasms
Glioblastoma
Glioblastoma
Blood-Brain Barrier
Research Output 1985 2019
2
Citations
(Scopus)
Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases
Gampa, G., Kim, M., Mohammad, A. S., Parrish, K. E., Mladek, A. C., Sarkaria, J. N. & Elmquist, W. F., Mar 1 2019, In : The Journal of pharmacology and experimental therapeutics. 368, 3, p. 446-461 16 p.Research output: Contribution to journal › Article
Open Access
Melanoma
Neoplasm Metastasis
P-Glycoprotein
Brain
Mitogen-Activated Protein Kinase Kinases
2
Citations
(Scopus)
Brain distribution of a panel of epidermal growth factor receptor inhibitors using cassette dosing in wild-type and ABCB1/ABCG2-deficient mice
Kim, M., Laramy, J. K., Mohammad, A. S., Talele, S., Fisher, J., Sarkaria, J. N. & Elmquist, W. F., Apr 1 2019, In : Drug Metabolism and Disposition. 47, 4, p. 393-404 12 p.Research output: Contribution to journal › Article
Epidermal Growth Factor Receptor
Brain
Blood-Brain Barrier
Non-Small Cell Lung Carcinoma
Brain Neoplasms
1
Citation
(Scopus)
E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases
Babiker, H. M., Byron, S. A., Hendricks, W. P. D., Elmquist, W. F., Gampa, G., Vondrak, J., Aldrich, J., Cuyugan, L., Adkins, J., De Luca, V., Tibes, R., Borad, M. J., Marceau, K., Myers, T. J., Paradiso, L. J., Liang, W. S., Korn, R. L., Cridebring, D., Von Hoff, D. D., Carpten, J. D. & 3 others, , Aug 15 2019, In : Investigational New Drugs. 37, 4, p. 636-645 10 p.Research output: Contribution to journal › Article
Melanoma
Neoplasm Metastasis
Brain
Blood-Brain Barrier
Exome
3
Citations
(Scopus)
Barriers to Effective Drug Treatment for Brain Metastases: A Multifactorial Problem in the Delivery of Precision Medicine
Kim, M., Kizilbash, S. H., Laramy, J. K., Gampa, G., Parrish, K. E., Sarkaria, J. N. & Elmquist, W. F., Sep 1 2018, In : Pharmaceutical research. 35, 9, 177.Research output: Contribution to journal › Review article
Drug therapy
Precision Medicine
Medicine
Brain
Neoplasm Metastasis
7
Citations
(Scopus)
Brain distribution of a novel MEK Inhibitor E6201: Implications in the treatment of melanoma brain metastases
Gampa, G., Kim, M., Cook-Rostie, N., Laramy, J. K., Sarkaria, J. N., Paradiso, L., DePalatis, L. & Elmquist, W. F., May 1 2018, In : Drug Metabolism and Disposition. 46, 5, p. 658-666 9 p.Research output: Contribution to journal › Article
Open Access
Mitogen-Activated Protein Kinase Kinases
Melanoma
Neoplasm Metastasis
Brain
P-Glycoprotein