William F Elmquist

1984 …2020
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 4 Similar Profiles
Brain Medicine & Life Sciences
P-Glycoprotein Medicine & Life Sciences
Blood-Brain Barrier Medicine & Life Sciences
Microdialysis Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences

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Projects 1984 2020

Blood-Brain Barrier
Brain
Pharmaceutical Preparations
Therapeutics
Program Evaluation
Brain Neoplasms
Natural Science Disciplines
Brain Neoplasms
Pharmaceutical Preparations
Glioblastoma

Research Output 1985 2019

2 Citations (Scopus)

Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases

Gampa, G., Kim, M., Mohammad, A. S., Parrish, K. E., Mladek, A. C., Sarkaria, J. N. & Elmquist, W. F., Mar 1 2019, In : The Journal of pharmacology and experimental therapeutics. 368, 3, p. 446-461 16 p.

Research output: Contribution to journalArticle

Open Access
Melanoma
Neoplasm Metastasis
P-Glycoprotein
Brain
Mitogen-Activated Protein Kinase Kinases
2 Citations (Scopus)

Brain distribution of a panel of epidermal growth factor receptor inhibitors using cassette dosing in wild-type and ABCB1/ABCG2-deficient mice

Kim, M., Laramy, J. K., Mohammad, A. S., Talele, S., Fisher, J., Sarkaria, J. N. & Elmquist, W. F., Apr 1 2019, In : Drug Metabolism and Disposition. 47, 4, p. 393-404 12 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Brain
Blood-Brain Barrier
Non-Small Cell Lung Carcinoma
Brain Neoplasms
1 Citation (Scopus)

E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases

Babiker, H. M., Byron, S. A., Hendricks, W. P. D., Elmquist, W. F., Gampa, G., Vondrak, J., Aldrich, J., Cuyugan, L., Adkins, J., De Luca, V., Tibes, R., Borad, M. J., Marceau, K., Myers, T. J., Paradiso, L. J., Liang, W. S., Korn, R. L., Cridebring, D., Von Hoff, D. D., Carpten, J. D. & 3 others, Craig, D. W., Trent, J. M. & Gordon, M. S., Aug 15 2019, In : Investigational New Drugs. 37, 4, p. 636-645 10 p.

Research output: Contribution to journalArticle

Melanoma
Neoplasm Metastasis
Brain
Blood-Brain Barrier
Exome
5 Citations (Scopus)

Barriers to Effective Drug Treatment for Brain Metastases: A Multifactorial Problem in the Delivery of Precision Medicine

Kim, M., Kizilbash, S. H., Laramy, J. K., Gampa, G., Parrish, K. E., Sarkaria, J. N. & Elmquist, W. F., Sep 1 2018, In : Pharmaceutical research. 35, 9, 177.

Research output: Contribution to journalReview article

Drug therapy
Precision Medicine
Medicine
Brain
Neoplasm Metastasis
7 Citations (Scopus)

Brain distribution of a novel MEK Inhibitor E6201: Implications in the treatment of melanoma brain metastases

Gampa, G., Kim, M., Cook-Rostie, N., Laramy, J. K., Sarkaria, J. N., Paradiso, L., DePalatis, L. & Elmquist, W. F., May 1 2018, In : Drug Metabolism and Disposition. 46, 5, p. 658-666 9 p.

Research output: Contribution to journalArticle

Open Access
Mitogen-Activated Protein Kinase Kinases
Melanoma
Neoplasm Metastasis
Brain
P-Glycoprotein