Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Development of the brain penetrant ATM inhibitor WSD0628 in combination with radiation for recurrent high grade glioma
Elmquist, W. F. (PI)
MAYO CLINIC ROCHESTER, DHHS FOOD & DRUG ADMINISTRATION (FDA)
9/10/23 → 5/31/25
Project: Research project
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In vivo SELEX strategies to identify potent aptamer-drug conjugates for glioblastoma
Elmquist, W. F. (PI)
MAYO CLINIC ROCHESTER, NATIONAL INSTITUTES OF HEALTH (NIH)
8/21/23 → 7/31/25
Project: Research project
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Role of RBBP4/p300 Complex in Recovery from therapy induced DNA damage in glioblastoma
Kitange, G. (PI), Elmquist, W. F. (CoI), Wang, J. (CoI) & Zhang, L. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
4/1/22 → 6/30/25
Project: Research project
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Project TDG: Targeting the DDR in Glioblastoma
Elmquist, W. F. (PI)
YALE UNIVERSITY, National Brain Tumor Society Inc.
10/15/21 → 10/14/25
Project: Research project
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Intrathecal delivery of radiation sensitizing nanoparticles in pediatric neuro-oncology
Elmquist, W. F. (PI)
UNIVERSITY OF MASSACHUSETTS, NATIONAL INSTITUTES OF HEALTH (NIH)
12/16/22 → 6/30/24
Project: Research project
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Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization
Chen, J., Laverty, D. J., Talele, S., Bale, A., Carlson, B. L., Porath, K. A., Bakken, K. K., Burgenske, D. M., Decker, P. A., Vaubel, R. A., Eckel-Passow, J. E., Bhargava, R., Lou, Z., Hamerlik, P., Harley, B., Elmquist, W. F., Nagel, Z. D., Gupta, S. K. & Sarkaria, J. N., 2024, In: Science Translational Medicine. 16, 734, eadj5962.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Altering distribution profile of palbociclib by its prodrugs
Järvinen, J., Montaser, A. B., Adla, S. K., Leppänen, J., Lehtonen, M., Vellonen, K. S., Laitinen, T., Jalkanen, A., Elmquist, W. F., Timonen, J., Huttunen, K. M. & Rautio, J., Jan 1 2024, In: European Journal of Pharmaceutical Sciences. 192, 106637.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models
Jain, S., Griffith, J. I., Porath, K. A., Rathi, S., Le, J., Pasa, T. I., Decker, P. A., Gupta, S. K., Hu, Z., Carlson, B. L., Bakken, K., Burgenske, D. M., Feldsien, T. M., Lefebvre, D. R., Vaubel, R. A., Eckel-Passow, J. E., Reilly, E. B., Elmquist, W. F. & Sarkaria, J. N., Aug 1 2024, In: Clinical Cancer Research. 30, 15, p. 3287-3297 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Delivery versus Potency in Treating Brain Tumors: BI-907828, a MDM2-p53 Antagonist with Limited BBB Penetration but Significant In Vivo Efficacy in Glioblastoma
Zhang, W., Vaubel, R. A., Oh, J. H., Mladek, A. C., Talele, S., Zhang, W., Waller, K. L., Burgenske, D. M., Sarkaria, J. N. & Elmquist, W. F., Jan 10 2024, In: Molecular Cancer Therapeutics. 23, 1, p. 47-55 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts
Ji, J., Dragojevic, S., Callaghan, C. M., Smith, E. J., Talele, S., Zhang, W., Connors, M. A., Mladek, A. C., Hu, Z., Bakken, K. K., Sarkaria, P. P., Carlson, B. L., Burgenske, D. M., Decker, P. A., Rashid, M. A., Jang, M. H., Gupta, S. K., Eckel-Passow, J. E., Elmquist, W. F. & Sarkaria, J. N., May 1 2024, In: Molecular Cancer Therapeutics. 23, 5, p. 662-671 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations