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Wen Sheng

1994 …2022
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Microglia Medicine & Life Sciences
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Chemokines Medicine & Life Sciences

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Projects 2008 2022

Immunotherapy to enhance anti-HIV-1 responses against viral brain infection

Lokensgard, J. R. & Sheng, W.

NIH Nat'l Institute of Mental Health

4/1/19 → 12/31/19

Project: Research project

Virus Diseases
Immunotherapy
HIV-1
Brain

Anti-HIV-1 recall responses from brain-resident memory C

Lokensgard, J. R. & Sheng, W.

NIH NAT INST OF NEURO DISORDERS & STROKE

1/1/18 → 12/31/22

Project: Research project

human immunodeficiency virus
brain
neurotoxicity

Neuroimmune approaches to retrovirus infection-induced n

Lokensgard, J. R., Rock, R. B., Sheng, W. & Simone, D. A.

NIH NIDA NATL INST ON DRUG AB

6/1/16 → 5/31/21

Project: Research project

Protective effects of cannabinoids in HIV neuropathogene

Rock, R. B., Hu, S., Peterson, P. K. & Sheng, W.

NIH NIDA NATL INST ON DRUG AB

9/1/08 → 12/30/13

Project: Research project

Cannabinoids
HIV

Research Output 1994 2019

Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain

Sheng, W. S., Chauhan, P., Hu, S., Prasad, S. & Lokensgard, J. R., 2019, In : Pain Research and Management. 2019, p. 1260353

Research output: Contribution to journal › Article

Retroviridae Infections
Cannabinoid Receptors
Neuralgia
Spinal Cord
Macrophage Activation
3 Citations (Scopus)

Nitrosative damage during retrovirus infection-induced neuropathic pain

Chauhan, P., Sheng, W., Hu, S., Prasad, S. & Lokensgard, J. R., Mar 5 2018, In : Journal of Neuroinflammation. 15, 1, 66.

Research output: Contribution to journal › Article

Open Access
Retroviridae Infections
Neuralgia
Spinal Cord
Spinal Ganglia
Spinal Nerve Roots
4 Citations (Scopus)

Reactive glia promote development of CD103+CD69+ CD8+ T-cells through programmed cell death-ligand 1 (PD-L1)

Prasad, S., Hu, S., Sheng, W., Chauhan, P. & Lokensgard, J. R., Jun 1 2018, In : Immunity Inflammation and Disease. 6, 2, p. 332-344 13 p.

Research output: Contribution to journal › Article

Neuroglia
Cell Death
CD274 Antigen
Ligands
T-Lymphocytes
6 Citations (Scopus)

Modulation of Microglial Cell Fcγ Receptor Expression Following Viral Brain Infection

Chauhan, P., Hu, S., Sheng, W., Prasad, S. & Lokensgard, J. R., Feb 6 2017, In : Scientific reports. 7, 41889.

Research output: Contribution to journal › Article

Open Access
Fc Receptors
Virus Diseases
Microglia
Muromegalovirus
Brain
15 Citations (Scopus)

The PD-1: PD-L1 pathway promotes development of brain-resident memory T cells following acute viral encephalitis

Prasad, S., Hu, S., Sheng, W., Chauhan, P., Singh, A. & Lokensgard, J. R., Apr 13 2017, In : Journal of Neuroinflammation. 14, 1, 82.

Research output: Contribution to journal › Article

Viral Encephalitis
T-Lymphocytes
Brain
Wild Animals
Population