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Research Output 1994 2019

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Article
2012
8 Citations (Scopus)

Increased iris-lens contact following spontaneous blinking: Mathematical modeling

Amini, R., Jouzdani, S. & Barocas, V. H., Aug 31 2012, In : Journal of Biomechanics. 45, 13, p. 2293-2296 4 p.

Research output: Contribution to journalArticle

Contact lenses
Blinking
Contact Lenses
Iris
Anterior Chamber
51 Citations (Scopus)
Fibrin
Collagen
Gels
Biopolymers
Mechanical testing
28 Citations (Scopus)

Mechanical changes in the rat right ventricle with decellularization

Witzenburg, C., Raghupathy, R., Kren, S. M., Taylor, D. A. & Barocas, V. H., Mar 15 2012, In : Journal of Biomechanics. 45, 5, p. 842-849 8 p.

Research output: Contribution to journalArticle

Heart Ventricles
Rats
Anisotropy
Tissue
Stiffness
15 Citations (Scopus)
Indentation
Collagen
Mechanics
Kinematics
Tissue
38 Citations (Scopus)

Mechanics of a fiber network within a non-fibrillar matrix: Model and comparison with collagen-agarose co-gels

Lake, S. P., Hadi, M. F., Lai, V. & Barocas, V. H., Oct 1 2012, In : Annals of Biomedical Engineering. 40, 10, p. 2111-2121 11 p.

Research output: Contribution to journalArticle

Collagen
Mechanics
Gels
Fibers
Tissue
21 Citations (Scopus)

Microstructural and mechanical differences between digested collagen-fibrin co-gels and pure collagen and fibrin gels

Lai, V., Frey, C. R., Kerandi, A. M., Lake, S. P., Tranquillo, R. T. & Barocas, V. H., Jan 1 2012, In : Acta Biomaterialia. 8, 11, p. 4031-4042 12 p.

Research output: Contribution to journalArticle

Fibrin
Collagen
Gels
Proteins
Biopolymers
27 Citations (Scopus)

Multiscale model predicts tissue-level failure from collagen fiber-level damage

Hadi, M. F., Sander, E. A. & Barocas, V. H., Sep 7 2012, In : Journal of Biomechanical Engineering. 134, 9, 91005.

Research output: Contribution to journalArticle

Collagen
Tissue
Fibers
Gels
Physical Phenomena
33 Citations (Scopus)

Simulated remodeling of loaded collagen networks via strain-dependent enzymatic degradation and constant-rate fiber growth

Hadi, M. F., Sander, E. A., Ruberti, J. W. & Barocas, V. H., Jan 1 2012, In : Mechanics of Materials. 44, p. 72-82 11 p.

Research output: Contribution to journalArticle

collagens
Collagen
degradation
multiscale models
Degradation

Telescopic time-scale bridging for modeling dispersion in rapidly oscillating flows

Balachandran, R. K., Roychowdhury, J., Dorfman, K. D. & Barocas, V. H., Jul 1 2012, In : AIChE Journal. 58, 7, p. 1987-1997 11 p.

Research output: Contribution to journalArticle

Oscillating flow
Liquid sloshing
Vitreous Body
Pharmaceutical Preparations
Geometry
9 Citations (Scopus)

The posterior location of the dilator muscle induces anterior Iris bowing during dilation, even in the absence of pupillary block

Amini, R., Whitcomb, J. E., Al-Qaisi, M. K., Akkin, T., Jouzdani, S., Dorairaj, S., Prata, T., Illitchev, E., Liebmann, J. M., Ritch, R. & Barocas, V. H., Mar 1 2012, In : Investigative Ophthalmology and Visual Science. 53, 3, p. 1188-1194 7 p.

Research output: Contribution to journalArticle

Iris
Dilatation
Muscles
Optical Coherence Tomography
Computer Simulation
2011
11 Citations (Scopus)

Anterior-posterior asymmetry in iris mechanics measured by indentation

Whitcomb, J. E., Amini, R., Simha, N. K. & Barocas, V. H., Oct 1 2011, In : Experimental Eye Research. 93, 4, p. 475-481 7 p.

Research output: Contribution to journalArticle

Iris
Mechanics
Swine
Smooth Muscle
Actins
24 Citations (Scopus)

Collagen-agarose co-gels as a model for collagen-matrix interaction in soft tissues subjected to indentation

Lake, S. P., Hald, E. S. & Barocas, V. H., Dec 15 2011, In : Journal of Biomedical Materials Research - Part A. 99 A, 4, p. 507-515 9 p.

Research output: Contribution to journalArticle

Indentation
Collagen
Sepharose
Gels
Tissue
10 Citations (Scopus)

Computational simulation of altitude change-induced intraocular pressure alteration in patients with intravitreal gas bubbles

Amini, R., Barocas, V. H., Kavehpour, H. P. & Hubschman, J. P., Sep 1 2011, In : Retina. 31, 8, p. 1656-1663 8 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Gases
Aqueous Humor
Oceans and Seas
Theoretical Models
19 Citations (Scopus)

Contribution of saccadic motion to intravitreal drug transport: Theoretical analysis

Balachandran, R. K. & Barocas, V. H., May 1 2011, In : Pharmaceutical research. 28, 5, p. 1049-1064 16 p.

Research output: Contribution to journalArticle

Liquid sloshing
Pharmaceutical Preparations
Vitreous Body
Eye movements
Saccades
30 Citations (Scopus)

Identification of regional mechanical anisotropy in soft tissue analogs

Raghupathy, R., Witzenburg, C., Lake, S. P., Sander, E. A. & Barocas, V. H., Oct 28 2011, In : Journal of Biomechanical Engineering. 133, 9, 091011.

Research output: Contribution to journalArticle

Anisotropy
Tissue
Mechanics
Elastomers
Polarization Microscopy
41 Citations (Scopus)
Fibroblasts
Gels
Collagen
Geometry
Fibers
46 Citations (Scopus)

Mechanical and structural contribution of non-fibrillar matrix in uniaxial tension: A collagen-agarose co-gel model

Lake, S. P. & Barocas, V. H., Jul 1 2011, In : Annals of Biomedical Engineering. 39, 7, p. 1891-1903 13 p.

Research output: Contribution to journalArticle

Collagen
Gels
Tissue
Structural properties
Mechanical properties
2010
8 Citations (Scopus)

Elasticity of the porcine lens capsule as measured by osmotic swelling

Powell, T. A., Amini, R., Oltean, A., Barnett, V. A., Dorfman, K. D., Segal, Y. & Barocas, V. H., Sep 1 2010, In : Journal of Biomechanical Engineering. 132, 9, 91008-1.

Research output: Contribution to journalArticle

Elasticity
Lenses
Capsules
Swelling
Swine
39 Citations (Scopus)

Freeze-thaw induced biomechanical changes in arteries: Role of collagen matrix and smooth muscle cells

Venkatasubramanian, R. T., Wolkers, W. F., Shenoi, M. M., Barocas, V. H., Lafontaine, D., Soule, C. L., Iaizzo, P. A. & Bischof, J. C., Mar 1 2010, In : Annals of Biomedical Engineering. 38, 3, p. 694-706 13 p.

Research output: Contribution to journalArticle

Collagen
Muscle
Cells
Biomechanics
Dehydration
20 Citations (Scopus)

Generalized anisotropic inverse mechanics for soft tissues

Raghupathy, R. & Barocas, V. H., Aug 1 2010, In : Journal of Biomechanical Engineering. 132, 8

Research output: Contribution to journalArticle

Mechanics
Tissue
Anisotropy
Inverse problems
Elasticity Imaging Techniques
37 Citations (Scopus)

Pericellular conditions regulate extent of cell-mediated compaction of collagen gels

Stevenson, M. D., Sieminski, A. L., McLeod, C. M., Byfield, F. J., Barocas, V. H. & Gooch, K. J., Jul 7 2010, In : Biophysical journal. 99, 1, p. 19-28 10 p.

Research output: Contribution to journalArticle

Collagen
Gels
Extracellular Matrix
Traction
Tissue Engineering
6 Citations (Scopus)

Pigment dispersion syndrome patients do not have larger-than-normal irides

Trastman-Caruso, E., Dorairaj, S., Barocas, V. H., Tello, C., Liebmann, J. M. & Ritch, R., Sep 1 2010, In : Journal of Glaucoma. 19, 7, p. 493-496 4 p.

Research output: Contribution to journalArticle

Iris
Ciliary Body
Glaucoma-Related Pigment Dispersion Syndrome
Acoustic Microscopy
Trabecular Meshwork
12 Citations (Scopus)

Reverse pupillary block slows iris contour recovery from corneoscleral indentation

Amini, R. & Barocas, V. H., Jul 1 2010, In : Journal of Biomechanical Engineering. 132, 7

Research output: Contribution to journalArticle

Iris
Indentation
Recovery
Fluid structure interaction
Aqueous Humor
2009
43 Citations (Scopus)

A closed-form structural model of planar fibrous tissue mechanics

Raghupathy, R. & Barocas, V. H., Jul 22 2009, In : Journal of Biomechanics. 42, 10, p. 1424-1428 5 p.

Research output: Contribution to journalArticle

Structural Models
Mechanics
Tissue
Fibers
Stress Fibers
9 Citations (Scopus)

A dissolution-diffusion model for the TAXUS™ drug-eluting stent with surface burst estimated from continuum percolation

Barocas, V., William, D., Girton, T., Guler, I., Knapp, D., Moeller, J. & Parsonage, E., Jan 1 2009, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 90, 1, p. 267-274 8 p.

Research output: Contribution to journalArticle

Stents
Dissolution
Pharmaceutical Preparations
Paclitaxel
Polymer matrix
22 Citations (Scopus)
Sclera
Anterior Chamber
Gonioscopy
Cornea
Iris
81 Citations (Scopus)

Comparison of 2D fiber network orientation measurement methods

Sander, E. A. & Barocas, V. H., Feb 1 2009, In : Journal of Biomedical Materials Research - Part A. 88, 2, p. 322-331 10 p.

Research output: Contribution to journalArticle

Fourier transforms
Fibers
Microstructure
Anisotropy
Tissue
18 Citations (Scopus)

Ex vivo porcine iris stiffening due to drug stimulation

Whitcomb, J. E., Barnett, V. A., Olsen, T. W. & Barocas, V. H., Oct 1 2009, In : Experimental Eye Research. 89, 4, p. 456-461 6 p.

Research output: Contribution to journalArticle

Iris
Swine
Pilocarpine
Pharmaceutical Preparations
Tropicamide
32 Citations (Scopus)

Image-based biomechanics of collagen-based tissue equivalents

Sander, E., Stylianopoulos, T., Tranquillo, R. & Barocas, V., May 1 2009, In : IEEE Engineering in Medicine and Biology Magazine. 28, 3, p. 10-18 9 p., 4939184.

Research output: Contribution to journalArticle

Fibrillar Collagens
Biomedical Engineering
Biological Models
Finite Element Analysis
Mechanical Stress
104 Citations (Scopus)
Extracellular Matrix
Collagen
Gels
Anisotropy
Homeostasis
11 Citations (Scopus)

Multiscale computation for bioartificial soft tissues with complex geometries

Luo, X. J., Stylianopoulos, T., Barocas, V. H. & Shephard, M. S., Jan 1 2009, In : Engineering with Computers. 25, 1, p. 87-95 9 p.

Research output: Contribution to journalArticle

Multiscale Computation
Multiscale Model
Soft Tissue
Complex Geometry
Collagen
36 Citations (Scopus)

Planar biaxial mechanical behavior of bioartificial tissues possessing prescribed fiber alignment

Jhun, C. S., Evans, M. C., Barocas, V. H. & Tranquillo, R. T., Aug 1 2009, In : Journal of Biomechanical Engineering. 131, 8, 81006-1.

Research output: Contribution to journalArticle

Fungi
Tissue
Fibers
Anisotropy
Molds
2 Citations (Scopus)

Posterior chamber volume does not change significantly during dilation

Dorairaj, S., Liebmann, J. M., Tello, C., Barocas, V. H. & Ritch, R., Nov 1 2009, In : British Journal of Ophthalmology. 93, 11, p. 1514-1517 4 p.

Research output: Contribution to journalArticle

Dilatation
Light
Acoustic Microscopy
Refractive Errors
Anatomy
23 Citations (Scopus)
Fibroblasts
Collagen
Gels
Experiments
Compaction
2008
26 Citations (Scopus)

Accommodation-induced changes in iris curvature

Dorairaj, S., Oliveira, C., Fose, A. K., Liebmann, J. M., Tello, C., Barocas, V. H. & Ritch, R., Feb 1 2008, In : Experimental Eye Research. 86, 2, p. 220-225 6 p.

Research output: Contribution to journalArticle

Iris
Observation
Acoustic Microscopy
Meridians
Anterior Chamber
9 Citations (Scopus)

A structural, kinetic model of soft tissue thermomechanics

Stylianopoulos, T., Aksan, A. & Barocas, V. H., Jan 2 2008, In : Biophysical Journal. 94, 3, p. 717-725 9 p.

Research output: Contribution to journalArticle

Structural Models
Collagen
Monte Carlo Method
Patellar Ligament
Protein Folding
88 Citations (Scopus)

Computational predictions of the tensile properties of electrospun fibre meshes: Effect of fibre diameter and fibre orientation

Stylianopoulos, T., Bashur, C. A., Goldstein, A. S., Guelcher, S. A. & Barocas, V. H., Oct 1 2008, In : Journal of the Mechanical Behavior of Biomedical Materials. 1, 4, p. 326-335 10 p.

Research output: Contribution to journalArticle

Fiber reinforced materials
Tensile properties
Fibers
Scaffolds (biology)
Scaffolds
41 Citations (Scopus)

Computer modeling of drug delivery to the posterior eye: Effect of active transport and loss to choroidal blood flow

Balachandran, R. K. & Barocas, V. H., Nov 1 2008, In : Pharmaceutical research. 25, 11, p. 2685-2696 12 p.

Research output: Contribution to journalArticle

Active Biological Transport
Drug Design
Drug delivery
Blood
Pharmaceutical Preparations
3 Citations (Scopus)

Concentration control for protein crystallization via a continuously-fed crystallization chamber

Sugiyama, M., Sengupta, S., Todd, P. & Barocas, V. H., Jan 1 2008, In : Lab on a Chip. 8, 8, p. 1398-1401 4 p.

Research output: Contribution to journalArticle

Crystallization
Nucleation
Proteins
Enzyme kinetics
Growth kinetics
96 Citations (Scopus)

Functional tissue-engineered valves from cell-remodeled fibrin with commissural alignment of cell-produced collagen

Robinson, P. S., Johnson, S. L., Evans, M. C., Barocas, V. H. & Tranquillo, R. T., Jan 1 2008, In : Tissue Engineering - Part A.. 14, 1, p. 83-95 13 p.

Research output: Contribution to journalArticle

Fibrin
Collagen
Gels
Tissue
Fungi
11 Citations (Scopus)

Microstructure-based, multiscale modeling for the mechanical behavior of hydrated fiber networks

Chandran, P. L., Stylianopoulos, T. & Barocas, V. H., Jan 1 2008, In : Multiscale Modeling and Simulation. 7, 1, p. 22-43 22 p.

Research output: Contribution to journalArticle

Multiscale Modeling
Mechanical Behavior
Averaging
Microstructure
microstructure
59 Citations (Scopus)

Permeability calculations in three-dimensional isotropic and oriented fiber networks

Stylianopoulos, T., Yeckel, A., Derby, J. J., Luo, X. J., Shephard, M. S., Sander, E. A. & Barocas, V. H., Jan 1 2008, In : Physics of Fluids. 20, 12, 123601.

Research output: Contribution to journalArticle

permeability
fiber volume fraction
fibers
drag coefficients
parallel flow
3 Citations (Scopus)

Protein-salt-water solution phase diagram determination by a combined experimental-computational scheme

Sugiyama, M., Gasperino, D., Derby, J. J. & Barocas, V. H., Dec 1 2008, In : Crystal Growth and Design. 8, 12, p. 4208-4214 7 p.

Research output: Contribution to journalArticle

Saline water
Phase diagrams
chambers
phase diagrams
Muramidase
7 Citations (Scopus)

Simulation of flow around a thin, flexible obstruction by means of a deforming grid overlapping a fixed grid

Liu, K., Radhakrishnan, H. & Barocas, V. H., Feb 28 2008, In : International Journal for Numerical Methods in Fluids. 56, 6, p. 723-738 16 p.

Research output: Contribution to journalArticle

Obstruction
Pressure drop
Overlapping
Reynolds number
Elastic moduli
21 Citations (Scopus)

Three-dimensional simulation of anisotropic cell-driven collagen gel compaction

Ohsumi, T. K., Flaherty, J. E., Evans, M. C. & Barocas, V. H., Feb 1 2008, In : Biomechanics and Modeling in Mechanobiology. 7, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

Collagen
Compaction
collagens
Gels
gels
2007
66 Citations (Scopus)

Deterministic material-based averaging theory model of collagen gel micromechanics

Chandran, P. L. & Barocas, V. H., Apr 1 2007, In : Journal of Biomechanical Engineering. 129, 2, p. 137-147 11 p.

Research output: Contribution to journalArticle

Micromechanics
Collagen
Gels
Wounds and Injuries
Toes
73 Citations (Scopus)

Multiscale, structure-based modeling for the elastic mechanical behavior of arterial walls

Stylianopoulos, T. & Barocas, V. H., Aug 1 2007, In : Journal of Biomechanical Engineering. 129, 4, p. 611-618 8 p.

Research output: Contribution to journalArticle

Collagen
Arteries
Fibers
Microstructure
Structural Models
125 Citations (Scopus)

Volume-averaging theory for the study of the mechanics of collagen networks

Stylianopoulos, T. & Barocas, V. H., Jun 15 2007, In : Computer Methods in Applied Mechanics and Engineering. 196, 31-32, p. 2981-2990 10 p.

Research output: Contribution to journalArticle

collagens
Collagen
Mechanics
Microstructure
Tissue
2006
12 Citations (Scopus)

Accommodative microfluctuations and iris contour

Huang, E. C. & Barocas, V. H., May 12 2006, In : Journal of vision. 6, 5, p. 653-660 8 p., 10.

Research output: Contribution to journalArticle

Iris
Lenses
Aqueous Humor
Theoretical Models