If you made any changes in Pure, your changes will be visible here soon.

Research Output 1982 2018

Filter
Article
2018
1 Citation (Scopus)

Kinesin-5 Mediated Chromosome Congression in Insect Spindles

Tubman, E., He, Y., Hays, T. S. & Odde, D. J., Feb 1 2018, In : Cellular and Molecular Bioengineering. 11, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

Kinesin
Chromosomes, Human, Pair 5
Microtubules
Chromosomes
Chromosome

Single Molecule Studies Enabled by Model-Based Controller Design

Bhaban, S., Talukdar, S., Li, M-G., Hays, T. S., Seiler Jr, P. J. & salapaka, M. V., Aug 1 2018, In : IEEE/ASME Transactions on Mechatronics. 23, 4, p. 1532-1542 11 p., 8401903.

Research output: Contribution to journalArticle

Controllers
Molecules
Optical tweezers
Proteins
Thermal noise
2017
16 Citations (Scopus)
Open Access
Axonal Transport
Secretory Vesicles
Phosphoric Monoester Hydrolases
Phosphotransferases
Transcription Factor AP-1
4 Citations (Scopus)

Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation

Avery, A. W., Fealey, M. E., Wang, F., Orlova, A., Thompson, A. R., Thomas, D. D., Hays, T. S. & Egelman, E. H., Dec 1 2017, In : Nature communications. 8, 1, 1350.

Research output: Contribution to journalArticle

Open Access
ataxia
Spinocerebellar Ataxias
Spectrin
Missense Mutation
mutations
4 Citations (Scopus)
Open Access
Spinocerebellar Ataxias
Spectrin
Neuronal Plasticity
Mutation
Actins
2016
4 Citations (Scopus)

A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding

Avery, A. W., Crain, J., Thomas, D. D. & Hays, T. S., Feb 17 2016, In : Scientific reports. 6, 21375.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Spectrin
Actins
Mutation
Leucine
19 Citations (Scopus)

Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex in Drosophila

Mauvezin, C., Neisch, A. L., Ayala, C. I., Kim, J., Beltrame, A., Braden, C. R., Gardner, M. K., Hays, T. S. & Neufeld, T. P., Jan 1 2016, In : Journal of cell science. 129, 5, p. 971-982 12 p.

Research output: Contribution to journalArticle

Lysosomes
Drosophila
Kinesin
GTP Phosphohydrolases
Autophagy
4 Citations (Scopus)
Molecular Motor
Transport Properties
cargo
Transport properties
Ensemble
2015
2 Citations (Scopus)

Methods to identify and analyze gene products involved in neuronal intracellular transport using Drosophila

Neisch, A. L., Avery, A. W., Machamer, J. B., Li, M. G. & Hays, T. S., 2015, (Accepted/In press) In : Methods in Cell Biology.

Research output: Contribution to journalArticle

Drosophila
Genes
Neurons
Neuronal Plasticity
Motor Neurons
2013
5 Citations (Scopus)

An exact approach for studying cargo transport by an ensemble of molecular motors

Materassi, D., Roychowdhury, S., Hays, T. & Salapaka, M., Nov 16 2013, In : BMC Biophysics. 6, 1, 14.

Research output: Contribution to journalArticle

Proteins
Microtubules
2012
16 Citations (Scopus)

Detection of steps in single molecule data

Aggarwal, T., Materassi, D., Davison, R., Hays, T. & Salapaka, M., Mar 1 2012, In : Cellular and Molecular Bioengineering. 5, 1, p. 14-31 18 p.

Research output: Contribution to journalArticle

Probe
Molecules
Noise
Signal-To-Noise Ratio
Signal to noise ratio
54 Citations (Scopus)

Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

Reis, G. F., Yang, G., Szpankowski, L., Weaver, C., Shah, S. B., Robinson, J. T., Hays, T. S., Danuser, G. & Goldstein, L. S. B., May 1 2012, In : Molecular biology of the cell. 23, 9, p. 1700-1714 15 p.

Research output: Contribution to journalArticle

Kinesin
Axonal Transport
Drosophila
Amyloid beta-Protein Precursor
Dyneins
30 Citations (Scopus)

Relay of retrograde synaptogenic signals through axonal transport of BMP receptors

Smith, R. B., Machamer, J. B., Kim, N. C., Hays, T. S. & Marques, G., Aug 15 2012, In : Journal of cell science. 125, 16, p. 3752-3764 13 p.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein Receptors
Bone Morphogenetic Proteins
Axonal Transport
Presynaptic Terminals
Axons
2010
62 Citations (Scopus)

Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Dmsophila

Lorenzo, D. N., Li, M. G., Mische, S. E., Armbrust, K. R., Ronum, L. P. W. & Hays, T. S., Apr 5 2010, In : Journal of Cell Biology. 189, 1, p. 143-158 16 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Spectrin
Axonal Transport
Mutation
Diptera
2009
23 Citations (Scopus)

asunder is a critical regulator of dynein-dynactin localization during Drosophila spermatogenesis

Anderson, M. A., Jodoin, J. N., Lee, E., Hales, K. G., Hays, T. S. & Lee, L. A., Jun 1 2009, In : Molecular biology of the cell. 20, 11, p. 2709-2721 13 p.

Research output: Contribution to journalArticle

Dyneins
Spermatocytes
Spermatogenesis
Drosophila
Centrosome
2008
10 Citations (Scopus)

Dynein and star interact in EGFR signaling and ligand trafficking

Iyadurai, S. J. P., Robinson, J. T., Ma, L., He, Y., Mische, S., Li, M. G., Brown, W., Guichard, A., Bier, E. & Hays, T. S., Aug 15 2008, In : Journal of cell science. 121, 16, p. 2643-2651 9 p.

Research output: Contribution to journalArticle

Dyneins
Ligands
Mutation
Epidermal Growth Factor Receptor
Alleles
37 Citations (Scopus)

Dynein light intermediate chain: An essential subunit that contributes to spindle checkpoint inactivation

Mische, S., He, Y., Ma, L., Li, M., Serr, M. & Hays, T. S., Nov 1 2008, In : Molecular biology of the cell. 19, 11, p. 4918-4929 12 p.

Research output: Contribution to journalArticle

Dyneins
Light
Drosophila
Cytoplasmic Dyneins
Kinetochores
55 Citations (Scopus)

Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity

Li, Z., Wang, L., Hays, T. S. & Cai, Y., Jan 14 2008, In : Journal of Cell Biology. 180, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

Dyneins
3' Untranslated Regions
RNA Transport
Cytoplasmic Dyneins
Proteins
24 Citations (Scopus)

Motility screen identifies Drosophila IGF-II mRNA-binding protein - Zipcode-binding protein acting in oogenesis and synaptogenesis

Boylan, K. L. M., Mische, S., Li, M., Marqués, G., Morin, X., Chia, W. & Hays, T. S., Feb 1 2008, In : PLoS genetics. 4, 2

Research output: Contribution to journalArticle

insulin-like growth factor II
Oogenesis
protein binding
motility
oogenesis
2007
48 Citations (Scopus)

Direct observation of regulated ribonucleoprotein transport across the nurse cell/oocyte boundary

Mische, S., Li, M., Serr, M. & Hays, T. S., Jun 1 2007, In : Molecular biology of the cell. 18, 6, p. 2254-2263 10 p.

Research output: Contribution to journalArticle

Ribonucleoproteins
Oocytes
Nurses
Dyneins
Observation
39 Citations (Scopus)

Potential role for phosphorylation in differential regulation of the assembly of jdynein light chains

Song, Y., Benison, G., Nyarko, A., Hays, T. S. & Barbar, E., Jun 8 2007, In : Journal of Biological Chemistry. 282, 23, p. 17272-17279 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Light
Dyneins
Dimers
Binding Sites
40 Citations (Scopus)

The concentration of Nuf, a Rab11 effector, at the microtubule-organizing center is cell cycle-regulated, dynein-dependent, and coincides with furrow formation

Riggs, B., Fasulo, B., Royou, A., Mische, S., Cao, J., Hays, T. S. & Sullivan, W., Sep 1 2007, In : Molecular biology of the cell. 18, 9, p. 3313-3322 10 p.

Research output: Contribution to journalArticle

Microtubule-Organizing Center
Dyneins
Cell Cycle
Endosomes
pioglitazone
2006
15 Citations (Scopus)

Folding is coupled to dimerization of Tctex-1 dynein light chain

Talbott, M., Hare, M., Nyarko, A., Hays, T. S. & Barbar, E., Jun 6 2006, In : Biochemistry. 45, 22, p. 6793-6800 8 p.

Research output: Contribution to journalArticle

Dyneins
Fluorescence Polarization
Dimerization
Fluorescence
Anisotropy
2005
91 Citations (Scopus)

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

Siller, K. H., Serr, M., Steward, R., Hays, T. S. & Doe, C. Q., Nov 1 2005, In : Molecular biology of the cell. 16, 11, p. 5127-5140 14 p.

Research output: Contribution to journalArticle

M Phase Cell Cycle Checkpoints
Neuroimaging
Drosophila
Green Fluorescent Proteins
Dyneins
77 Citations (Scopus)

The golgin Lava lamp mediates dynein-based Golgi movements during Drosophila cellularization

Papoulas, O., Hays, T. S. & Sisson, J. C., Jun 1 2005, In : Nature Cell Biology. 7, 6, p. 612-618 7 p.

Research output: Contribution to journalArticle

Dyneins
Drosophila
Microtubules
Embryonic Structures
Cytoplasmic Dyneins
2004
52 Citations (Scopus)

Dynein Light Chain LC8 Promotes Assembly of the Coiled-Coil Domain of Swallow Protein

Wang, L., Hare, M., Hays, T. S. & Barbar, E., Apr 20 2004, In : Biochemistry. 43, 15, p. 4611-4620 10 p.

Research output: Contribution to journalArticle

Swallows
Dyneins
Deglutition
Cytoplasmic Dyneins
Spectroscopy
69 Citations (Scopus)

In Vivo Dynamics of the Rough Deal Checkpoint Protein during Drosophila Mitosis

Basto, R., Scaerou, F., Mische, S., Wojcik, E., Lefebvre, C., Gomes, R., Hays, T. S. & Karess, R., Jan 6 2004, In : Current Biology. 14, 1, p. 56-61 6 p.

Research output: Contribution to journalArticle

Dyneins
Kinetochores
kinetochores
Mitosis
mitosis
45 Citations (Scopus)
Cytoplasmic Dyneins
Dyneins
Spermatids
Drosophila
Light
59 Citations (Scopus)

The intermediate chain of cytoplasmic dynein is partially disordered and gains structure upon binding to light-chain LC8

Nyarko, A., Hare, M., Hays, T. S. & Barbar, E., Dec 14 2004, In : Biochemistry. 43, 49, p. 15595-15603 9 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Light
Binding Sites
Circular dichroism spectroscopy
2003
137 Citations (Scopus)

Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11

Riggs, B., Rothwell, W., Mische, S., Hickson, G. R. X., Matheson, J., Hays, T. S., Gould, G. W. & Sullivan, W., Oct 13 2003, In : Journal of Cell Biology. 163, 1, p. 143-154 12 p.

Research output: Contribution to journalArticle

Endosomes
Recycling
Actin Cytoskeleton
Drosophila
Actins
80 Citations (Scopus)

The third P-loop domain in cytoplasmic dynein heavy chain is essential for dynein motor function and ATP-sensitive microtubule binding

Silvanovich, A., Li, M. G., Serr, M., Mische, S. & Hays, T. S., Apr 1 2003, In : Molecular biology of the cell. 14, 4, p. 1355-1365 11 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Microtubules
Adenosine Triphosphate
Adenosine Triphosphatases
2002
76 Citations (Scopus)

Interactions of cytoplasmic dynein light chains Tctex-1 and LC8 with the intermediate chain IC74

Makokha, M., Hare, M., Li, M., Hays, T. & Barbar, E., Apr 2 2002, In : Biochemistry. 41, 13, p. 4302-4311 10 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Proteolysis
Dyneins
Circular Dichroism
Circular dichroism spectroscopy
24 Citations (Scopus)

The gene for the intermediate chain subunit of cytoplasmic dynein is essential in drosophila

Boylan, K. L. & Hays, T. S., Nov 1 2002, In : Genetics. 162, 3, p. 1211-1220 10 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Drosophila
Mutation
Genes
2001
71 Citations (Scopus)

Dimerization and folding of LC8, a highly conserved light chain of cytoplasmic dynein

Barbar, E., Kleinman, B., Imhoff, D., Li, M., Hays, T. S. & Hare, M., Feb 13 2001, In : Biochemistry. 40, 6, p. 1596-1605 10 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dimerization
Dyneins
Monomers
Dimers
157 Citations (Scopus)

Kinetochore dynein: Its dynamics and role in the transport of the Rough deal checkpoint protein

Wojcik, E., Basto, R., Serr, M., Scaírou, F., Karess, R. & Hays, T. S., Jan 1 2001, In : Nature Cell Biology. 3, 11, p. 1001-1007 7 p.

Research output: Contribution to journalArticle

Dyneins
Kinetochores
Metaphase
Prometaphase
Proteins
2000
30 Citations (Scopus)
Cytoplasmic Dyneins
Dyneins
Molecular Biology
Dynactin Complex
Genes
93 Citations (Scopus)

Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tension

King, J. M., Hays, T. S. & Nicklas, R. B., Nov 13 2000, In : Journal of Cell Biology. 151, 4, p. 739-748 10 p.

Research output: Contribution to journalArticle

Dyneins
Kinetochores
Microtubules
Staining and Labeling
Spermatocytes
68 Citations (Scopus)

The SCF ubiquitin ligase protein Slimb regulates centrosome dulplication in Drosophila

Wojcik, E. J., Glover, D. M. & Hays, T. S., Sep 21 2000, In : Current Biology. 10, 18, p. 1131-1134 4 p.

Research output: Contribution to journalArticle

SKP Cullin F-Box Protein Ligases
Cullin Proteins
F-Box Proteins
centrosomes
Cyclin E
1999
280 Citations (Scopus)

Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport

Martin, M. A., Iyadurai, S. J., Gassman, A., Gindhart, J. G., Hays, T. S. & Saxton, W. M., Nov 1999, In : Molecular biology of the cell. 10, 11, p. 3717-3728 12 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Kinesin
Axonal Transport
Dyneins
Mutation
167 Citations (Scopus)

Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila

Robinson, J. T., Wojcik, E. J., Sanders, M. A., McGrail, M. & Hays, T. S., Aug 9 1999, In : Journal of Cell Biology. 146, 3, p. 597-608 12 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Centrosome
Mitosis
Drosophila
19 Citations (Scopus)

Evidence for cooperative interactions between the two motor domains of cytoplasmic dynein

Iyadurai, S. J., Li, M-G., Gilbert, S. P. & Hays, T. S., Jul 15 1999, In : Current Biology. 9, 14, p. 771-774 4 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Microtubules
microtubules
cooperatives
59 Citations (Scopus)

Filamin is required for ring canal assembly and actin organization during Drosophila oogenesis

Li, M. G., Serr, M., Edwards, K., Ludmann, S., Yamamoto, D., Tilney, L. G., Field, C. M. & Hays, T. S., Jan 1 1999, In : Journal of Cell Biology. 146, 5, p. 1061-1073 13 p.

Research output: Contribution to journalArticle

Filamins
Oogenesis
Drosophila
Actins
Microfilament Proteins
1998
206 Citations (Scopus)

ZW10 helps recruit dynactin and dynein to the kinetochore

Starr, D. A., Williams, B. C., Hays, T. S. & Goldberg, M. L., Aug 10 1998, In : Journal of Cell Biology. 142, 3, p. 763-774 12 p.

Research output: Contribution to journalArticle

Dyneins
Kinetochores
Anaphase
Chromosomes
Metaphase
1997
191 Citations (Scopus)
Cytoplasmic Dyneins
Dyneins
Microtubules
Cell Division
Oogenesis
1996
107 Citations (Scopus)

Cytoplasmic dynein function is essential in Drosophila melanogaster

Gepner, J., Li, M-G., Ludmann, S., Kortas, C., Boylan, K. L., Iyadurai, S. J. P., McGrail, M. & Hays, T. S., Mar 1 1996, In : Genetics. 142, 3, p. 865-878 14 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Drosophila melanogaster
Drosophila
Genes
1995
113 Citations (Scopus)

Regulation of cytoplasmic dynein function in vivo by the Drosophila glued complex

McGrail, M., Gepner, J., Silvanovich, A., Ludmann, S., Serr, M. & Hays, T. S., Oct 1 1995, In : Journal of Cell Biology. 131, 2, p. 411-425 15 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Drosophila
Vertebrates
Oogenesis
1994
35 Citations (Scopus)

A cytoplasmic dynein motor in Drosophila: Identification and localization during embryogenesis

Hays, T. S., Porter, M. E., McGrail, M., Grissom, P., Gosch, P., Fuller, M. T. & McIntosh, J. R., Jun 1 1994, In : Journal of cell science. 107, 6, p. 1557-1569 13 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Microtubules
Drosophila
Embryonic Development
Dyneins
74 Citations (Scopus)

A family of dynein genes in Drosophila melanogaster

Rasmusson, K., Serr, M., Gepner, J., Gibbons, I. & Hays, T. S., Jan 1994, In : Molecular biology of the cell. 5, 1, p. 45-55 11 p.

Research output: Contribution to journalArticle

Dyneins
Drosophila melanogaster
Genes
Cytoplasmic Dyneins
Drosophila
130 Citations (Scopus)

Drosophila cytoplasmic dynein, a microtubule motor that is asymmetrically localized in the oocyte

Li, M. G., McGrail, M., Serr, M. & Hays, T. S., Sep 1994, In : Journal of Cell Biology. 126, 6, p. 1475-1494 20 p.

Research output: Contribution to journalArticle

Cytoplasmic Dyneins
Dyneins
Microtubules
Drosophila
Oocytes
148 Citations (Scopus)

Phylogeny and expression of axonemal and cytoplasmic dynein genes in sea urchins

Gibbons, B. H., Asai, D. J., Tang, W. J. Y., Hays, T. S. & Gibbons, I. R., Jan 1994, In : Molecular biology of the cell. 5, 1, p. 57-70 14 p.

Research output: Contribution to journalArticle

Axonemal Dyneins
Cytoplasmic Dyneins
Dyneins
Sea Urchins
Phylogeny