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Research Output

2018

Kinesin-5 Mediated Chromosome Congression in Insect Spindles

Tubman, E., He, Y., Hays, T. S. & Odde, D. J., Feb 1 2018, In : Cellular and Molecular Bioengineering. 11, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Single Molecule Studies Enabled by Model-Based Controller Design

Bhaban, S., Talukdar, S., Li, M., Hays, T., Seiler, P. & Salapaka, M., Aug 2018, In : IEEE/ASME Transactions on Mechatronics. 23, 4, p. 1532-1542 11 p., 8401903.

Research output: Contribution to journalArticle

2017
Open Access
17 Scopus citations

Drosophila cytoplasmic dynein: Mutations, tools, and developmental functions

Neisch, A. L., Avery, A. W., Li, M. G. & Hays, T. S., Nov 22 2017, Dyneins: The Biology of Dynein Motors: Second Edition. Elsevier Inc., p. 569-627 59 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation

Avery, A. W., Fealey, M. E., Wang, F., Orlova, A., Thompson, A. R., Thomas, D. D., Hays, T. S. & Egelman, E. H., Dec 1 2017, In : Nature communications. 8, 1, 1350.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
Open Access
5 Scopus citations
2016

A brief history of research on mitotic mechanisms

McIntosh, J. R. & Hays, T., Dec 2016, In : Biology. 5, 4, 55.

Research output: Contribution to journalReview article

9 Scopus citations

A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding

Avery, A. W., Crain, J., Thomas, D. D. & Hays, T. S., Feb 17 2016, In : Scientific reports. 6, 21375.

Research output: Contribution to journalArticle

6 Scopus citations

Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex in Drosophila

Mauvezin, C., Neisch, A. L., Ayala, C. I., Kim, J., Beltrame, A., Braden, C. R., Gardner, M. K., Hays, T. S. & Neufeld, T. P., Jan 1 2016, In : Journal of cell science. 129, 5, p. 971-982 12 p.

Research output: Contribution to journalArticle

20 Scopus citations
4 Scopus citations

Toward clinical genomics in everyday medicine: Perspectives and recommendations

Delaney, S. K., Hultner, M. L., Jacob, H. J., Ledbetter, D. H., McCarthy, J. J., Ball, M., Beckman, K. B., Belmont, J. W., Bloss, C. S., Christman, M. F., Cosgrove, A., Damiani, S. A., Danis, T., Delledonne, M., Dougherty, M. J., Dudley, J. T., Faucett, W. A., Friedman, J. R., Haase, D. H., Hays, T. S. & 25 others, Heilsberg, S., Huber, J., Kaminsky, L., Ledbetter, N., Lee, W. H., Levin, E., Libiger, O., Linderman, M., Love, R. L., Magnus, D. C., Martland, A., McClure, S. L., Megill, S. E., Messier, H., Nussbaum, R. L., Palaniappan, L., Patay, B. A., Popovich, B. W., Quackenbush, J., Savant, M. J., Su, M. M., Terry, S. F., Tucker, S., Wong, W. T. & Green, R. C., May 3 2016, In : Expert Review of Molecular Diagnostics. 16, 5, p. 521-532 12 p.

Research output: Contribution to journalReview article

37 Scopus citations
2015

Methods to identify and analyze gene products involved in neuronal intracellular transport using Drosophila

Neisch, A. L., Avery, A. W., Machamer, J. B., Li, M. G. & Hays, T. S., 2015, (Accepted/In press) In : Methods in Cell Biology.

Research output: Contribution to journalArticle

2 Scopus citations
2013

An exact approach for studying cargo transport by an ensemble of molecular motors

Materassi, D., Roychowdhury, S., Hays, T. & Salapaka, M., Nov 16 2013, In : BMC Biophysics. 6, 1, 14.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Detection of steps in single molecule data

Aggarwal, T., Materassi, D., Davison, R., Hays, T. & Salapaka, M., Mar 1 2012, In : Cellular and Molecular Bioengineering. 5, 1, p. 14-31 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

Reis, G. F., Yang, G., Szpankowski, L., Weaver, C., Shah, S. B., Robinson, J. T., Hays, T. S., Danuser, G. & Goldstein, L. S. B., May 1 2012, In : Molecular biology of the cell. 23, 9, p. 1700-1714 15 p.

Research output: Contribution to journalArticle

54 Scopus citations

Relay of retrograde synaptogenic signals through axonal transport of BMP receptors

Smith, R. B., Machamer, J. B., Kim, N. C., Hays, T. S. & Marques, G., Aug 15 2012, In : Journal of cell science. 125, 16, p. 3752-3764 13 p.

Research output: Contribution to journalArticle

31 Scopus citations
2010

Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Dmsophila

Lorenzo, D. N., Li, M. G., Mische, S. E., Armbrust, K. R., Ronum, L. P. W. & Hays, T. S., Apr 5 2010, In : Journal of Cell Biology. 189, 1, p. 143-158 16 p.

Research output: Contribution to journalArticle

64 Scopus citations
2009

asunder is a critical regulator of dynein-dynactin localization during Drosophila spermatogenesis

Anderson, M. A., Jodoin, J. N., Lee, E., Hales, K. G., Hays, T. S. & Lee, L. A., Jun 1 2009, In : Molecular biology of the cell. 20, 11, p. 2709-2721 13 p.

Research output: Contribution to journalArticle

23 Scopus citations
2008

Dynein and star interact in EGFR signaling and ligand trafficking

Iyadurai, S. J. P., Robinson, J. T., Ma, L., He, Y., Mische, S., Li, M. G., Brown, W., Guichard, A., Bier, E. & Hays, T. S., Aug 15 2008, In : Journal of cell science. 121, 16, p. 2643-2651 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dynein light intermediate chain: An essential subunit that contributes to spindle checkpoint inactivation

Mische, S., He, Y., Ma, L., Li, M., Serr, M. & Hays, T. S., Nov 1 2008, In : Molecular biology of the cell. 19, 11, p. 4918-4929 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity

Li, Z., Wang, L., Hays, T. S. & Cai, Y., Jan 14 2008, In : Journal of Cell Biology. 180, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Motility screen identifies Drosophila IGF-II mRNA-binding protein - Zipcode-binding protein acting in oogenesis and synaptogenesis

Boylan, K. L. M., Mische, S., Li, M., Marqués, G., Morin, X., Chia, W. & Hays, T. S., Feb 1 2008, In : PLoS genetics. 4, 2

Research output: Contribution to journalArticle

25 Scopus citations
2007

Direct observation of regulated ribonucleoprotein transport across the nurse cell/oocyte boundary

Mische, S., Li, M., Serr, M. & Hays, T. S., Jun 1 2007, In : Molecular biology of the cell. 18, 6, p. 2254-2263 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Potential role for phosphorylation in differential regulation of the assembly of jdynein light chains

Song, Y., Benison, G., Nyarko, A., Hays, T. S. & Barbar, E., Jun 8 2007, In : Journal of Biological Chemistry. 282, 23, p. 17272-17279 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

The concentration of Nuf, a Rab11 effector, at the microtubule-organizing center is cell cycle-regulated, dynein-dependent, and coincides with furrow formation

Riggs, B., Fasulo, B., Royou, A., Mische, S., Cao, J., Hays, T. S. & Sullivan, W., Sep 1 2007, In : Molecular biology of the cell. 18, 9, p. 3313-3322 10 p.

Research output: Contribution to journalArticle

41 Scopus citations
2006

Folding is coupled to dimerization of Tctex-1 dynein light chain

Talbott, M., Hare, M., Nyarko, A., Hays, T. S. & Barbar, E., Jun 6 2006, In : Biochemistry. 45, 22, p. 6793-6800 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2005

Cytoplasmic dynein nomenclature

Kevin Pfister, K., Fisher, E. M. C., Gibbons, I. R., Hays, T. S., Holzbaur, E. L. F., Richard McIntosh, J., Porter, M. E., Schroer, T. A., Vaughan, K. T., Witman, G. B., King, S. M. & Vallee, R. B., Nov 7 2005, In : Journal of Cell Biology. 171, 3, p. 411-413 3 p.

Research output: Contribution to journalReview article

138 Scopus citations

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control

Siller, K. H., Serr, M., Steward, R., Hays, T. S. & Doe, C. Q., Nov 1 2005, In : Molecular biology of the cell. 16, 11, p. 5127-5140 14 p.

Research output: Contribution to journalArticle

92 Scopus citations

The golgin Lava lamp mediates dynein-based Golgi movements during Drosophila cellularization

Papoulas, O., Hays, T. S. & Sisson, J. C., Jun 1 2005, In : Nature Cell Biology. 7, 6, p. 612-618 7 p.

Research output: Contribution to journalArticle

78 Scopus citations
2004

Dynein Light Chain LC8 Promotes Assembly of the Coiled-Coil Domain of Swallow Protein

Wang, L., Hare, M., Hays, T. S. & Barbar, E., Apr 20 2004, In : Biochemistry. 43, 15, p. 4611-4620 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

In Vivo Dynamics of the Rough Deal Checkpoint Protein during Drosophila Mitosis

Basto, R., Scaerou, F., Mische, S., Wojcik, E., Lefebvre, C., Gomes, R., Hays, T. & Karess, R., Jan 6 2004, In : Current Biology. 14, 1, p. 56-61 6 p.

Research output: Contribution to journalArticle

72 Scopus citations
45 Scopus citations

The intermediate chain of cytoplasmic dynein is partially disordered and gains structure upon binding to light-chain LC8

Nyarko, A., Hare, M., Hays, T. S. & Barbar, E., Dec 14 2004, In : Biochemistry. 43, 49, p. 15595-15603 9 p.

Research output: Contribution to journalArticle

59 Scopus citations
2003

Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11

Riggs, B., Rothwell, W., Mische, S., Hickson, G. R. X., Matheson, J., Hays, T. S., Gould, G. W. & Sullivan, W., Oct 13 2003, In : Journal of Cell Biology. 163, 1, p. 143-154 12 p.

Research output: Contribution to journalArticle

138 Scopus citations

The third P-loop domain in cytoplasmic dynein heavy chain is essential for dynein motor function and ATP-sensitive microtubule binding

Silvanovich, A., Li, M. G., Serr, M., Mische, S. & Hays, T. S., Apr 1 2003, In : Molecular biology of the cell. 14, 4, p. 1355-1365 11 p.

Research output: Contribution to journalArticle

81 Scopus citations
2002

Interactions of cytoplasmic dynein light chains Tctex-1 and LC8 with the intermediate chain IC74

Makokha, M., Hare, M., Li, M., Hays, T. & Barbar, E., Apr 2 2002, In : Biochemistry. 41, 13, p. 4302-4311 10 p.

Research output: Contribution to journalArticle

78 Scopus citations

The gene for the intermediate chain subunit of cytoplasmic dynein is essential in drosophila

Boylan, K. L. M. & Hays, T. S., Nov 1 2002, In : Genetics. 162, 3, p. 1211-1220 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2001

Dimerization and folding of LC8, a highly conserved light chain of cytoplasmic dynein

Barbar, E., Kleinman, B., Imhoff, D., Li, M., Hays, T. S. & Hare, M., Feb 13 2001, In : Biochemistry. 40, 6, p. 1596-1605 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

Kinesin transport: Driving kinesin in the neuron

Hays, T. & Li, M. G., Feb 20 2001, In : Current Biology. 11, 4, p. R136-R139

Research output: Contribution to journalReview article

3 Scopus citations

Kinetochore dynein: Its dynamics and role in the transport of the Rough deal checkpoint protein

Wojcik, E., Basto, R., Serr, M., Scaírou, F., Karess, R. & Hays, T., Jan 1 2001, In : Nature Cell Biology. 3, 11, p. 1001-1007 7 p.

Research output: Contribution to journalArticle

159 Scopus citations
2000
30 Scopus citations

Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tension

King, J. M., Hays, T. S. & Nicklas, R. B., Nov 13 2000, In : Journal of Cell Biology. 151, 4, p. 739-748 10 p.

Research output: Contribution to journalArticle

93 Scopus citations

Swallowing dynein: A missing link in RNA localization?

Hays, T. S. & Karess, R., Nov 7 2000, In : Nature Cell Biology. 2, 4

Research output: Contribution to journalShort survey

15 Scopus citations

The SCF ubiquitin ligase protein Slimb regulates centrosome dulplication in Drosophila

Wojcik, E. J., Glover, D. M. & Hays, T. S., Sep 21 2000, In : Current Biology. 10, 18, p. 1131-1134 4 p.

Research output: Contribution to journalArticle

68 Scopus citations
1999

Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport

Martin, M. A., Iyadurai, S. J., Gassman, A., Gindhart, J. G., Hays, T. S. & Saxton, W. M., Nov 1999, In : Molecular biology of the cell. 10, 11, p. 3717-3728 12 p.

Research output: Contribution to journalArticle

281 Scopus citations

Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila

Robinson, J. T., Wojcik, E. J., Sanders, M. A., McGrail, M. & Hays, T. S., Aug 9 1999, In : Journal of Cell Biology. 146, 3, p. 597-608 12 p.

Research output: Contribution to journalArticle

169 Scopus citations

Evidence for cooperative interactions between the two motor domains of cytoplasmic dynein

Iyadurai, S. J., Li, M-G., Gilbert, S. P. & Hays, T. S., Jul 15 1999, In : Current Biology. 9, 14, p. 771-774 4 p.

Research output: Contribution to journalArticle

19 Scopus citations

Filamin is required for ring canal assembly and actin organization during Drosophila oogenesis

Li, M. G., Serr, M., Edwards, K., Ludmann, S., Yamamoto, D., Tilney, L. G., Field, C. M. & Hays, T. S., Jan 1 1999, In : Journal of Cell Biology. 146, 5, p. 1061-1073 13 p.

Research output: Contribution to journalArticle

59 Scopus citations
1998

ZW10 helps recruit dynactin and dynein to the kinetochore

Starr, D. A., Williams, B. C., Hays, T. S. & Goldberg, M. L., Aug 10 1998, In : Journal of Cell Biology. 142, 3, p. 763-774 12 p.

Research output: Contribution to journalArticle

207 Scopus citations
1997
194 Scopus citations