1995 …2024
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Genes Medicine & Life Sciences
Saccharomyces cerevisiae Medicine & Life Sciences
E2F Transcription Factors Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Yeast Chemical Compounds
ATP-Binding Cassette Transporters Medicine & Life Sciences
Retinoblastoma Medicine & Life Sciences
Drug Resistance Medicine & Life Sciences

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Projects 2008 2024

phosphatidylinositol 3-kinase
cells
phosphatidylinositol 3-kinase
cells

Research Output 1995 2017

1 Citation (Scopus)

Retinoblastoma cells activate the AKT pathway and are vulnerable to the PI3K/mTOR inhibitor NVP-BEZ235

Xie, C., Freeman, M. J., Lu, H., Wang, X., Forster, C. L., Sarver, A. L. & Hallstrom, T. C., Jan 1 2017, In : Oncotarget. 8, 24, p. 38084-38098 15 p.

Research output: Contribution to journalArticle

Open Access
Phosphatidylinositol 3-Kinase
Retinoblastoma
Apoptosis
Topotecan
Carboplatin
5 Citations (Scopus)

Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity

Lu, H., Bhoopatiraju, S., Wang, H., Schmitz, N. P., Wang, X., Freeman, M. J., Forster, C. L., Verneris, M. R., Linden, M. A. & Hallstrom, T. C., Jan 1 2016, In : Oncotarget. 7, 46, p. 76047-76061 15 p.

Research output: Contribution to journalArticle

Leukemia
Neoplasms
Methylation
Lymphoid Progenitor Cells
Myeloid Progenitor Cells
13 Citations (Scopus)

Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas

Xie, C., Lu, H., Nomura, A., Hanse, E. A., Forster, C. L., Parker, J. B., Linden, M. A., Karasch, C. & Hallstrom, T. C., Apr 24 2015, In : Molecular Cancer. 14, 1, 93.

Research output: Contribution to journalArticle

Retinoblastoma
Stem Cells
Apoptosis
Phosphatidylinositol 3-Kinases
Retina
3 Citations (Scopus)

Rb1 and Pten co-deletion in osteoblast precursor cells causes rapid lipoma formation in mice

Filtz, E. A., Emery, A., Lu, H., Forster, C. L., Karasch, C., Hallstrom, T. C. & Shi, X. M., Aug 28 2015, In : PloS one. 10, 8, e0136729.

Research output: Contribution to journalArticle

lipoma
osteoblasts
Lipoma
Osteoblasts
Tumors
16 Citations (Scopus)

The nuclear protein UHRF2 is a direct target of the transcription factor E2F1 in the induction of apoptosis

Lu, H. & Hallstrom, T. C., Aug 16 2013, In : Journal of Biological Chemistry. 288, 33, p. 23833-23843 11 p.

Research output: Contribution to journalArticle

E2F1 Transcription Factor
Nuclear Proteins
Apoptosis
Tumors
Neoplasms