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  • 3 Similar Profiles
TNF-Related Apoptosis-Inducing Ligand Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
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TNF-Related Apoptosis-Inducing Ligand Receptors Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Cell Death Medicine & Life Sciences

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Projects 2011 2023

Sepsis
B-Lymphocytes
T-Lymphocytes
Sepsis
T-Lymphocytes
Sepsis
T-Lymphocytes

BioThera

Griffith, T. S.

BIOTHERA

3/1/1512/31/16

Project: Research project

Allergy and Immunology

Research Output 1994 2019

Combination of Sunitinib and PD-L1 Blockade Enhances Anticancer Efficacy of TLR7/8 Agonist-Based Nanovaccine

Kim, H., Khanna, V., Kucaba, T. A., Zhang, W., Ferguson, D. M., Griffith, T. S. & Panyam, J., Mar 4 2019, In : Molecular pharmaceutics. 16, 3, p. 1200-1210 11 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Ligands
T-Lymphocytes
Tumor Microenvironment
Nanoparticles

Cutting edge: Polymicrobial sepsis has the capacity to reinvigorate tumor-infiltrating CD8 T cells and prolong host survival

Danahy, D. B., Jensen, I. J., Griffith, T. S. & Badovinac, V. P., May 15 2019, In : Journal of Immunology. 202, 10, p. 2843-2848 6 p.

Research output: Contribution to journalArticle

Sepsis
T-Lymphocytes
Survival
Neoplasms
Ligation
15 Citations (Scopus)

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

Wang, Z., Aguilar, E. G., Luna, J. I., Dunai, C., Khuat, L. T., Le, C. T., Mirsoian, A., Minnar, C. M., Stoffel, K. M., Sturgill, I. R., Grossenbacher, S. K., Withers, S. S., Rebhun, R. B., Hartigan-O’Connor, D. J., Méndez-Lagares, G., Tarantal, A. F., Isseroff, R. R., Griffith, T. S., Schalper, K. A., Merleev, A. & 13 othersSaha, A., Maverakis, E., Kelly, K., Aljumaily, R., Ibrahimi, S., Mukherjee, S., Machiorlatti, M., Vesely, S. K., Longo, D. L., Blazar, B. R., Canter, R. J., Murphy, W. J. & Monjazeb, A. M., Jan 1 2019, In : Nature Medicine. 25, 1, p. 141-151 11 p.

Research output: Contribution to journalArticle

Open Access
T-cells
Tumors
Obesity
T-Lymphocytes
Neoplasms
2 Citations (Scopus)

Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy

Kim, H., Sehgal, D., Kucaba, T. A., Ferguson, D. M., Griffith, T. S. & Panyam, J., Nov 28 2018, In : Nanoscale. 10, 44, p. 20851-20862 12 p.

Research output: Contribution to journalArticle

Polymers
Nanoparticles
T-cells
Gases
Antigens

Cutting edge: Elevated leptin during diet-induced obesity reduces the efficacy of tumor immunotherapy

Murphy, K. A., James, B. R., Sjaastad, F. V., Kucaba, T. A., Kim, H., Brincks, E. L., Chua, S. C., Wilber, A. & Griffith, T. S., Oct 1 2018, In : Journal of Immunology. 201, 7, p. 1837-1841 5 p.

Research output: Contribution to journalArticle

Leptin
Immunotherapy
Obesity
Diet
Neoplasms