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Research Output 1972 2019

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2019

Benzyne Cascade Reactions via Benzoxetenonium Ions and Their Rearrangements to o-Quinone Methides

Shen, H., Xiao, X. & Hoye, T. R., Mar 15 2019, In : Organic Letters. 21, 6, p. 1672-1675 4 p.

Research output: Contribution to journalArticle

quinones
cascades
Ions
carbon
isomerization
glycidol
Cyclic Ethers
Ethylene Oxide
Ethers
cleavage

Superabsorbent Poly(isoprenecarboxylate) Hydrogels from Glucose

Fahnhorst, G. W. & Hoye, T. R., Apr 15 2019, In : ACS Sustainable Chemistry and Engineering. 7, 8, p. 7491-7495 5 p.

Research output: Contribution to journalArticle

Open Access
Hydrogels
Independent component analysis
Glucose
glucose
sodium
2018
8 Citations (Scopus)

A Carbomethoxylated Polyvalerolactone from Malic Acid: Synthesis and Divergent Chemical Recycling

Fahnhorst, G. W. & Hoye, T. R., Feb 20 2018, In : ACS Macro Letters. 7, 2, p. 143-147 5 p.

Research output: Contribution to journalArticle

Recycling
Monomers
Polyesters
Acids
Polymers
2 Citations (Scopus)

A Traceless Tether Strategy for Achieving Formal Intermolecular Hexadehydro-Diels-Alder Reactions

Smela, M. P. & Hoye, T. R., Sep 7 2018, In : Organic Letters. 20, 17, p. 5502-5505 4 p.

Research output: Contribution to journalArticle

Diels-Alder reactions
Alkynes
Cycloaddition Reaction
alkynes
Diynes
1 Citation (Scopus)

Atypical Mode of [3 + 2]-Cycloaddition: Pseudo-1,3-dipole Behavior in Reactions of Electron-Deficient Thioamides with Benzynes

Zhang, J., Page, A. C. S., Palani, V., Chen, J. & Hoye, T. R., Sep 21 2018, In : Organic Letters. 20, 18, p. 5550-5553 4 p.

Research output: Contribution to journalArticle

Thioamides
Cycloaddition
Cycloaddition Reaction
cycloaddition
Ammonium Compounds
9 Citations (Scopus)

Benzocyclobutadienes: An Unusual Mode of Access Reveals Unusual Modes of Reactivity

Xiao, X., Woods, B. P., Xiu, W. & Hoye, T. R., Jul 26 2018, In : Angewandte Chemie - International Edition. 57, 31, p. 9901-9905 5 p.

Research output: Contribution to journalArticle

Alkynes
Electrons
Discrete Fourier transforms
Joining
benzocyclobutadiene
Bearings (structural)
Boron
Carbon
Metals
carbene

Cu I -Mediated Bromoalkynylation and Hydroalkynylation Reactions of Unsymmetrical Benzynes: Complementary Modes of Addition

Xiao, X., Wang, T., Xu, F. & Hoye, T. R., Dec 10 2018, In : Angewandte Chemie - International Edition. 57, 50, p. 16564-16568 5 p.

Research output: Contribution to journalArticle

Alkynes
Substrates
Copper
Heating
1 Citation (Scopus)

Engineering the production of dipicolinic acid in E. coli

McClintock, M. K., Fahnhorst, G. W., Hoye, T. R. & Zhang, K., Jul 1 2018, In : Metabolic Engineering. 48, p. 208-217 10 p.

Research output: Contribution to journalArticle

Escherichia coli
Acids
Genes
Clostridium
Polyesters

Fatty-acid derivative acts as a sea lamprey migratory pheromone

Li, K., Brant, C. O., Huertas, M., Hessler, E. J., Mezei, G., Scott, A. M., Hoye, T. R. & Li, W., Aug 21 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 34, p. 8603-8608 6 p.

Research output: Contribution to journalArticle

Petromyzon
Pheromones
Fishes
Fatty Acids
Cues
3 Citations (Scopus)
Cycloaddition Reaction
trapping
traps
Diels-Alder reactions
Atoms

Isomerization of Linear to Hyperbranched Polymers: Two Isomeric Lactones Converge via Metastable Isostructural Polyesters to a Highly Branched Analogue

Fahnhorst, G. W., Stasiw, D. E., Tolman, W. B. & Hoye, T. R., Oct 16 2018, In : ACS Macro Letters. 7, 10, p. 1144-1148 5 p.

Research output: Contribution to journalArticle

Polyesters
Lactones
Isomerization
Polymers
Transesterification
1 Citation (Scopus)
Isomerization
isomerization
Hot Temperature
propadiene
8 Citations (Scopus)

Multiheterocyclic Motifs via Three-Component Reactions of Benzynes, Cyclic Amines, and Protic Nucleophiles

Ross, S. P. & Hoye, T. R., Jan 5 2018, In : Organic Letters. 20, 1, p. 100-103 4 p.

Research output: Contribution to journalArticle

Nucleophiles
nucleophiles
Ammonium Compounds
Amines
amines
1 Citation (Scopus)

Poly(α-methyleneglutarimide)s from radical polymerization of α-methyleneglutarimides

Wang, Y., Xu, S. & Hoye, T. R., May 1 2018, In : Journal of Polymer Science, Part A: Polymer Chemistry. 56, 9, p. 1020-1027 8 p.

Research output: Contribution to journalArticle

Anhydrides
Niacin
Free radical polymerization
Acids
Metabolites

Reactions of Diaziridines with Benzynes Give N-Arylhydrazones

Arora, S., Palani, V. & Hoye, T. R., Dec 21 2018, In : Organic Letters. 20, 24, p. 8082-8085 4 p.

Research output: Contribution to journalArticle

Hydrazones
Alkynes
Nitrogen
Carbon
Electrons

Sulfonamide-Trapping Reactions of Thermally Generated Benzynes

Wang, Y., Zheng, L. & Hoye, T. R., Nov 16 2018, In : Organic Letters. 20, 22, p. 7145-7148 4 p.

Research output: Contribution to journalArticle

zwitterions
Sulfonamides
trapping
rings
Substrates
14 Citations (Scopus)
Polyacetylenes
Aromatic polymers
Field effect transistors
Organic compounds
Electronic properties
4 Citations (Scopus)

Unraveling substituent effects on the glass transition temperatures of biorenewable polyesters

Yu, X., Jia, J., Xu, S., Lao, K. U., Sanford, M. J., Ramakrishnan, R. K., Nazarenko, S. I., Hoye, T. R., Coates, G. W. & DiStasio, R. A., Dec 1 2018, In : Nature Communications. 9, 1, 2880.

Research output: Contribution to journalArticle

Polyesters
Transition Temperature
polyesters
glass transition temperature
Glass
2017
6 Citations (Scopus)

Bile Salt-like Dienones Having a Novel Skeleton or a Rare Substitution Pattern Function as Chemical Cues in Adult Sea Lamprey

Li, K., Scott, A. M., Brant, C. O., Fissette, S. D., Riedy, J. J., Hoye, T. R. & Li, W., Sep 1 2017, In : Organic Letters. 19, 17, p. 4444-4447 4 p.

Research output: Contribution to journalArticle

Petromyzon
cues
Biological Products
Bile Acids and Salts
musculoskeletal system
6 Citations (Scopus)
Amines
amines
Amino Alcohols
Nucleophiles
nucleophiles
21 Citations (Scopus)
Alnus
Cycloaddition Reaction
Electronic states
Hot Temperature
Byproducts
35 Citations (Scopus)

Reactions of hexadehydro-Diels-Alder benzynes with structurally complex multifunctional natural products

Ross, S. P. & Hoye, T. R., Jun 1 2017, In : Nature Chemistry. 9, 6, p. 523-530 8 p.

Research output: Contribution to journalArticle

Alkaloids
Biological Products
Cinchona Alkaloids
Tropolone
Quinidine
5 Citations (Scopus)

Thermoplastic polyurethanes from β-methyl-δ-valerolactone-derived amidodiol chain extenders

Guptill, D. M., Brutman, J. P. & Hoye, T. R., Feb 24 2017, In : Polymer. 111, p. 252-257 6 p.

Research output: Contribution to journalArticle

Polyurethanes
Thermoplastics
Polyols
Functional groups
Glucose
1 Citation (Scopus)

Trapping of Hexadehydro-Diels-Alder Benzynes with Exocyclic, Conjugated Enals as a Route to Fused Spirocyclic Benzopyran Motifs

Wang, T., Oswood, C. J. & Hoye, T. R., Dec 18 2017, In : Synlett. 28, 20, p. 2933-2935 3 p.

Research output: Contribution to journalArticle

Benzopyrans
Cycloaddition
Aldehydes
Derivatives
Heating
2016
11 Citations (Scopus)

Blue-Emitting Arylalkynyl Naphthalene Derivatives via a Hexadehydro-Diels-Alder Cascade Reaction

Xu, F., Hershey, K. W., Holmes, R. J. & Hoye, T. R., Oct 5 2016, In : Journal of the American Chemical Society. 138, 39, p. 12739-12742 4 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
Naphthalene
Light emitting diodes
Naphthalenes
Derivatives
11 Citations (Scopus)

Diels-Alder Reactions of Furans with Itaconic Anhydride: Overcoming Unfavorable Thermodynamics

Pehere, A. D., Xu, S., Thompson, S. K., Hillmyer, M. A. & Hoye, T. R., Jun 3 2016, In : Organic Letters. 18, 11, p. 2584-2587 4 p.

Research output: Contribution to journalArticle

Furans
Diels-Alder reactions
Anhydrides
furans
Cycloaddition Reaction
42 Citations (Scopus)
Murraya
Alkaloids
Cycloaddition
Cycloaddition Reaction
Pedigree

Isolation and characterization of sclerienone c from scleria striatinux

Nyongbela, K. D., Makolo, F. L., Hoye, T. R. & Efange, S. M. N., Jan 23 2016, In : Natural Product Communications. 11, 1, p. 5-6 2 p.

Research output: Contribution to journalArticle

Sesquiterpenes
sesquiterpenoids
Cameroon
Spices
antimalarials
3 Citations (Scopus)

Poly(isoprenecarboxylates) from Glucose via Anhydromevalonolactone

Ball-Jones, N., Fahnhorst, G. W. & Hoye, T. R., Oct 18 2016, In : ACS Macro Letters. 5, 10, p. 1128-1131 4 p.

Research output: Contribution to journalArticle

Glucose
Esters
Acids
Molecular weight
Acrylates
9 Citations (Scopus)

Reactions of HDDA-Derived Benzynes with Perylenes: Rapid Construction of Polycyclic Aromatic Compounds

Xu, F., Xiao, X. & Hoye, T. R., Nov 4 2016, In : Organic Letters. 18, 21, p. 5636-5639 4 p.

Research output: Contribution to journalArticle

Polycyclic Compounds
Diels-Alder reactions
aromatic compounds
Aromatic compounds
Cycloaddition Reaction
42 Citations (Scopus)

Reactions of HDDA-Derived Benzynes with Sulfides: Mechanism, Modes, and Three-Component Reactions

Chen, J., Palani, V. & Hoye, T. R., Apr 20 2016, In : Journal of the American Chemical Society. 138, 13, p. 4318-4321 4 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
Sulfides
Betaines
Betaine
Proton transfer
26 Citations (Scopus)
Alnus
Alkynes
Cycloaddition
Cyclization
Cycloaddition Reaction
19 Citations (Scopus)

The pentadehydro-Diels-Alder reaction

Wang, T., Naredla, R. R., Thompson, S. K. & Hoye, T. R., Apr 28 2016, In : Nature. 532, 7600, p. 484-488 5 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
Alnus
Hydrogen
Nitriles
Alkynes
17 Citations (Scopus)

The Phenol-Ene Reaction: Biaryl Synthesis via Trapping Reactions between HDDA-Generated Benzynes and Phenolics

Zhang, J., Niu, D., Brinker, V. A. & Hoye, T. R., Nov 4 2016, In : Organic Letters. 18, 21, p. 5596-5599 4 p.

Research output: Contribution to journalArticle

Alnus
Phenols
Phenol
phenols
trapping
2015
15 Citations (Scopus)
Petromyzon
Enantiomers
enantiomers
fatty acids
chromatography
12 Citations (Scopus)
Alnus
Cycloaddition Reaction
Data storage equipment
Alkynes
Substrates
21 Citations (Scopus)

Diels-Alderase-free, bis-pericyclic, [4+2] dimerization in the biosynthesis of (±)-paracaseolide A

Wang, T. & Hoye, T. R., Aug 25 2015, In : Nature Chemistry. 7, 8, p. 641-645 5 p.

Research output: Contribution to journalArticle

Dimerization
Biosynthesis
Cycloaddition
Metabolites
Biological Products
1 Citation (Scopus)

Differential cytotoxic activity of the petroleum ether extract and its furanosesquiterpenoid constituents from Commiphora molmol resin

Ayyad, S. E. N., Hoye, T. R., Alarif, W. M., Al Ahmadi, S. M., Basaif, S. A., Ghandourah, M. A. & Badria, F. A., Jan 1 2015, In : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 70, 3-4, p. 87-92 6 p.

Research output: Contribution to journalArticle

Commiphora
Resins
Cells
Trientine
Cell Line
21 Citations (Scopus)

Intramolecular [4 + 2] trapping of a hexadehydro-diels-alder (HDDA) benzyne by tethered arenes

Pogula, V. D., Wang, T. & Hoye, T. R., Feb 20 2015, In : Organic Letters. 17, 4, p. 856-859 4 p.

Research output: Contribution to journalArticle

Methane
trapping
Electrons
rings
adducts
4 Citations (Scopus)

iso-petromyroxols: Novel dihydroxylated tetrahydrofuran enantiomers from sea lamprey (Petromyzon marinus)

Li, K., Brant, C. O., Bussy, U., Pinnamaneni, H., Patel, H., Hoye, T. R. & Li, W., Mar 1 2015, In : Molecules. 20, 3, p. 5215-5222 8 p.

Research output: Contribution to journalArticle

Petromyzon
antipodes
Furans
larvae
Enantiomers
32 Citations (Scopus)
Alkynes
Density functional theory
Diynes
Wave functions
Kinetics
12 Citations (Scopus)

Nanoparticles Containing High Loads of Paclitaxel-Silicate Prodrugs: Formulation, Drug Release, and Anticancer Efficacy

Han, J., Michel, A. R., Lee, H., Kalscheuer, S., Wohl, A., Hoye, T. R., McCormick, A. V., Panyam, J. & Macosko, C., Oct 27 2015, In : Molecular pharmaceutics. 12, 12, p. 4329-4335 7 p.

Research output: Contribution to journalArticle

Silicates
Prodrugs
Paclitaxel
Nanoparticles
Hydrophobic and Hydrophilic Interactions
6 Citations (Scopus)

New cytotoxic cyclic peroxide acids from Plakortis sp. marine sponge

Hoye, T. R., Alarif, W. M., Basaif, S. S., Abo-Elkarm, M., Hamann, M. T., Wahba, A. E. & Ayyad, S. E. N., Apr 5 2015, In : Arkivoc. 2015, 5, p. 164-175 12 p.

Research output: Contribution to journalArticle

Peroxides
Acids
Bioassay
Lactones
Cytotoxicity
2014
146 Citations (Scopus)

A guide to small-molecule structure assignment through computation of (1 H and 13 C) NMR chemical shifts

Willoughby, P. H., Jansma, M. J. & Hoye, T. R., Jan 1 2014, In : Nature Protocols. 9, 3, p. 643-660 18 p.

Research output: Contribution to journalArticle

Chemical shift
Mechanics
Libraries
Protons
Carbon
22 Citations (Scopus)

Analysis of seven-membered lactones by computational nmr methods: Proton NMR chemical shift data are more discriminating than carbon

Marell, D. J., Emond, S. J., Kulshrestha, A. & Hoye, T. R., Jan 17 2014, In : Journal of Organic Chemistry. 79, 2, p. 752-758 7 p.

Research output: Contribution to journalArticle

Chemical shift
Lactones
Computational methods
Protons
Carbon
16 Citations (Scopus)

Cycloaddition reactions of azide, furan, and pyrrole units with benzynes generated by the hexadehydro-diels-alder (HDDA) reaction

Chen, J., Baire, B. & Hoye, T. R., Jan 1 2014, In : Heterocycles. 88, 2, p. 1191-1200 10 p.

Research output: Contribution to journalArticle

Pyrroles
Azides
Cycloaddition
Cycloaddition Reaction
Hot Temperature
33 Citations (Scopus)

Dichlorination of (hexadehydro-diels-alder generated) benzynes and a protocol for interrogating the kinetic order of bimolecular aryne trapping reactions

Niu, D., Wang, T., Woods, B. P. & Hoye, T. R., Jan 3 2014, In : Organic Letters. 16, 1, p. 254-257 4 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
Diels-Alder reactions
trapping
Kinetics
kinetics
11 Citations (Scopus)

Differential scanning calorimetry (DSC) as a tool for probing the reactivity of polyynes relevant to hexadehydro-diels-alder (HDDA) cascades

Woods, B. P. & Hoye, T. R., Dec 19 2014, In : Organic Letters. 16, 24, p. 6370-6373 4 p.

Research output: Contribution to journalArticle

Polyacetylenes
Differential Scanning Calorimetry
Differential scanning calorimetry
cascades
heat measurement