1972 …2023
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Research Output 1972 2019

2019

Benzyne Cascade Reactions via Benzoxetenonium Ions and Their Rearrangements to o-Quinone Methides

Shen, H., Xiao, X. & Hoye, T. R., Mar 15 2019, In : Organic Letters. 21, 6, p. 1672-1675 4 p.

Research output: Contribution to journalArticle

quinones
cascades
Ions
carbon
isomerization
1 Citation (Scopus)
glycidol
Cyclic Ethers
Ethylene Oxide
Ethers
cleavage

Hydrolytically-degradable homo- and copolymers of a strained exocyclic hemiacetal ester

Neitzel, A. E., Barreda, L., Trotta, J. T., Fahnhorst, G. W., Haversang, T. J., Hoye, T. R., Fors, B. P. & Hillmyer, M. A., Sep 7 2019, In : Polymer Chemistry. 10, 33, p. 4573-4583 11 p.

Research output: Contribution to journalArticle

Homopolymerization
Ethers
Esters
Copolymers
Molar mass
1 Citation (Scopus)

One-Pot, Three-Aryne Cascade Strategy for Naphthalene Formation from 1,3-Diynes and 1,2-Benzdiyne Equivalents

Xiao, X. & Hoye, T. R., Jun 26 2019, In : Journal of the American Chemical Society. 141, 25, p. 9813-9818 6 p.

Research output: Contribution to journalArticle

Diynes
Cycloaddition Reaction
Naphthalene
Hot Temperature
benzyne

Reactions of thermally generated benzynes with six-membered: N -heteroaromatics: Pathway and product diversity

Arora, S., Zhang, J., Pogula, V. & Hoye, T. R., Jan 1 2019, In : Chemical Science. 10, 39, p. 9069-9076 8 p.

Research output: Contribution to journalArticle

Open Access
Nucleophiles
Protonation
Discrete Fourier transforms
Ions
benzyne

Superabsorbent Poly(isoprenecarboxylate) Hydrogels from Glucose

Fahnhorst, G. W. & Hoye, T. R., Apr 15 2019, In : ACS Sustainable Chemistry and Engineering. 7, 8, p. 7491-7495 5 p.

Research output: Contribution to journalArticle

Open Access
Hydrogels
Independent component analysis
Glucose
glucose
sodium
2018
9 Citations (Scopus)

A Carbomethoxylated Polyvalerolactone from Malic Acid: Synthesis and Divergent Chemical Recycling

Fahnhorst, G. W. & Hoye, T. R., Feb 20 2018, In : ACS Macro Letters. 7, 2, p. 143-147 5 p.

Research output: Contribution to journalArticle

Recycling
Monomers
Polyesters
Acids
Polymers
2 Citations (Scopus)

A Traceless Tether Strategy for Achieving Formal Intermolecular Hexadehydro-Diels-Alder Reactions

Smela, M. P. & Hoye, T. R., Sep 7 2018, In : Organic Letters. 20, 17, p. 5502-5505 4 p.

Research output: Contribution to journalArticle

Diels-Alder reactions
Alkynes
Cycloaddition Reaction
alkynes
Diynes
4 Citations (Scopus)

Atypical Mode of [3 + 2]-Cycloaddition: Pseudo-1,3-dipole Behavior in Reactions of Electron-Deficient Thioamides with Benzynes

Zhang, J., Page, A. C. S., Palani, V., Chen, J. & Hoye, T. R., Sep 21 2018, In : Organic Letters. 20, 18, p. 5550-5553 4 p.

Research output: Contribution to journalArticle

Thioamides
Cycloaddition
Cycloaddition Reaction
cycloaddition
Ammonium Compounds
9 Citations (Scopus)

Benzocyclobutadienes: An Unusual Mode of Access Reveals Unusual Modes of Reactivity

Xiao, X., Woods, B. P., Xiu, W. & Hoye, T. R., Jul 26 2018, In : Angewandte Chemie - International Edition. 57, 31, p. 9901-9905 5 p.

Research output: Contribution to journalArticle

Alkynes
Electrons
Discrete Fourier transforms
Joining
benzocyclobutadiene
3 Citations (Scopus)

BF3-Promoted, Carbene-like, C-H Insertion Reactions of Benzynes

Shen, H., Xiao, X., Haj, M. K., Willoughby, P. H. & Hoye, T. R., Nov 21 2018, In : Journal of the American Chemical Society. 140, 46, p. 15616-15620 5 p.

Research output: Contribution to journalArticle

Bearings (structural)
Boron
Carbon
Metals
carbene
1 Citation (Scopus)

CuI-Mediated Bromoalkynylation and Hydroalkynylation Reactions of Unsymmetrical Benzynes: Complementary Modes of Addition

Xiao, X., Wang, T., Xu, F. & Hoye, T. R., Dec 10 2018, In : Angewandte Chemie - International Edition. 57, 50, p. 16564-16568 5 p.

Research output: Contribution to journalArticle

Alkynes
Substrates
Copper
Heating
1 Citation (Scopus)

Engineering the production of dipicolinic acid in E. coli

McClintock, M. K., Fahnhorst, G. W., Hoye, T. R. & Zhang, K., Jul 1 2018, In : Metabolic Engineering. 48, p. 208-217 10 p.

Research output: Contribution to journalArticle

Escherichia coli
Acids
Genes
Clostridium
Polyesters
1 Citation (Scopus)

Fatty-acid derivative acts as a sea lamprey migratory pheromone

Li, K., Brant, C. O., Huertas, M., Hessler, E. J., Mezei, G., Scott, A. M., Hoye, T. R. & Li, W., Aug 21 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 34, p. 8603-8608 6 p.

Research output: Contribution to journalArticle

Petromyzon
Pheromones
Fishes
Fatty Acids
Cues
5 Citations (Scopus)
Cycloaddition Reaction
trapping
traps
Diels-Alder reactions
Atoms

Isomerization of Linear to Hyperbranched Polymers: Two Isomeric Lactones Converge via Metastable Isostructural Polyesters to a Highly Branched Analogue

Fahnhorst, G. W., Stasiw, D. E., Tolman, W. B. & Hoye, T. R., Oct 16 2018, In : ACS Macro Letters. 7, 10, p. 1144-1148 5 p.

Research output: Contribution to journalArticle

Polyesters
Lactones
Isomerization
Polymers
Transesterification
1 Citation (Scopus)

Isomerizations of Propargyl 3-Acylpropiolates via Reactive Allenes

Wang, Y. & Hoye, T. R., Aug 3 2018, In : Organic Letters. 20, 15, p. 4425-4429 5 p.

Research output: Contribution to journalArticle

Isomerization
isomerization
Hot Temperature
propadiene
11 Citations (Scopus)

Multiheterocyclic Motifs via Three-Component Reactions of Benzynes, Cyclic Amines, and Protic Nucleophiles

Ross, S. P. & Hoye, T. R., Jan 5 2018, In : Organic Letters. 20, 1, p. 100-103 4 p.

Research output: Contribution to journalArticle

Nucleophiles
nucleophiles
Ammonium Compounds
Amines
amines
1 Citation (Scopus)

Poly(α-methyleneglutarimide)s from radical polymerization of α-methyleneglutarimides

Wang, Y., Xu, S. & Hoye, T. R., May 1 2018, In : Journal of Polymer Science, Part A: Polymer Chemistry. 56, 9, p. 1020-1027 8 p.

Research output: Contribution to journalArticle

Anhydrides
Niacin
Free radical polymerization
Acids
Metabolites
2 Citations (Scopus)

Reactions of Diaziridines with Benzynes Give N-Arylhydrazones

Arora, S., Palani, V. & Hoye, T. R., Dec 21 2018, In : Organic Letters. 20, 24, p. 8082-8085 4 p.

Research output: Contribution to journalArticle

Hydrazones
Alkynes
Nitrogen
Carbon
Electrons
1 Citation (Scopus)

Sulfonamide-Trapping Reactions of Thermally Generated Benzynes

Wang, Y., Zheng, L. & Hoye, T. R., Nov 16 2018, In : Organic Letters. 20, 22, p. 7145-7148 4 p.

Research output: Contribution to journalArticle

zwitterions
Sulfonamides
trapping
rings
Substrates
20 Citations (Scopus)
Polyacetylenes
Aromatic polymers
Field effect transistors
Organic compounds
Electronic properties
6 Citations (Scopus)

Unraveling substituent effects on the glass transition temperatures of biorenewable polyesters

Yu, X., Jia, J., Xu, S., Lao, K. U., Sanford, M. J., Ramakrishnan, R. K., Nazarenko, S. I., Hoye, T. R., Coates, G. W. & DiStasio, R. A., Dec 1 2018, In : Nature communications. 9, 1, 2880.

Research output: Contribution to journalArticle

Polyesters
Transition Temperature
polyesters
glass transition temperature
Glass
2017
1 Citation (Scopus)

Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment

Nyongbela, K. D., Ntie-Kang, F., Hoye, T. R. & Efange, S. M. N., Jun 1 2017, In : Natural Products and Bioprospecting. 7, 3, p. 235-247 13 p.

Research output: Contribution to journalArticle

Open Access
Antiparasitic Agents
Spices
Pharmacokinetics
Sesquiterpenes
spices
7 Citations (Scopus)

Bile Salt-like Dienones Having a Novel Skeleton or a Rare Substitution Pattern Function as Chemical Cues in Adult Sea Lamprey

Li, K., Scott, A. M., Brant, C. O., Fissette, S. D., Riedy, J. J., Hoye, T. R. & Li, W., Sep 1 2017, In : Organic Letters. 19, 17, p. 4444-4447 4 p.

Research output: Contribution to journalArticle

Petromyzon
cues
Biological Products
Bile Acids and Salts
musculoskeletal system
8 Citations (Scopus)

Mechanistic Duality in Tertiary Amine Additions to Thermally Generated Hexadehydro-Diels-Alder Benzynes

Ross, S. P., Baire, B. & Hoye, T. R., Oct 20 2017, In : Organic Letters. 19, 20, p. 5705-5708 4 p.

Research output: Contribution to journalArticle

Amines
amines
Amino Alcohols
Nucleophiles
nucleophiles

Molecular structure assignment simplified

Thompson, S. K. & Hoye, T. R., Jul 26 2017, In : Nature. 547, 7664, p. 410-411 2 p.

Research output: Contribution to journalShort survey

drug development
chemical bonding
laboratory method
molecular analysis
antibiotics
25 Citations (Scopus)

Photochemical Hexadehydro-Diels-Alder Reaction

Xu, F., Xiao, X. & Hoye, T. R., Jun 28 2017, In : Journal of the American Chemical Society. 139, 25, p. 8400-8403 4 p.

Research output: Contribution to journalArticle

Alnus
Cycloaddition Reaction
Electronic states
Hot Temperature
Byproducts
41 Citations (Scopus)

Reactions of hexadehydro-Diels-Alder benzynes with structurally complex multifunctional natural products

Ross, S. P. & Hoye, T. R., Jun 1 2017, In : Nature Chemistry. 9, 6, p. 523-530 8 p.

Research output: Contribution to journalArticle

Alkaloids
Biological Products
Cinchona Alkaloids
Tropolone
Quinidine
5 Citations (Scopus)

Thermoplastic polyurethanes from β-methyl-δ-valerolactone-derived amidodiol chain extenders

Guptill, D. M., Brutman, J. P. & Hoye, T. R., Feb 24 2017, In : Polymer. 111, p. 252-257 6 p.

Research output: Contribution to journalArticle

Polyurethanes
Thermoplastics
Polyols
Functional groups
Glucose
1 Citation (Scopus)

Trapping of Hexadehydro-Diels-Alder Benzynes with Exocyclic, Conjugated Enals as a Route to Fused Spirocyclic Benzopyran Motifs

Wang, T., Oswood, C. J. & Hoye, T. R., Dec 18 2017, In : Synlett. 28, 20, p. 2933-2935 3 p.

Research output: Contribution to journalArticle

Benzopyrans
Cycloaddition
Aldehydes
Derivatives
Heating
2016
13 Citations (Scopus)

Blue-Emitting Arylalkynyl Naphthalene Derivatives via a Hexadehydro-Diels-Alder Cascade Reaction

Xu, F., Hershey, K. W., Holmes, R. J. & Hoye, T. R., Oct 5 2016, In : Journal of the American Chemical Society. 138, 39, p. 12739-12742 4 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
Naphthalene
Light emitting diodes
Naphthalenes
Derivatives
11 Citations (Scopus)

Diels-Alder Reactions of Furans with Itaconic Anhydride: Overcoming Unfavorable Thermodynamics

Pehere, A. D., Xu, S., Thompson, S. K., Hillmyer, M. A. & Hoye, T. R., Jun 3 2016, In : Organic Letters. 18, 11, p. 2584-2587 4 p.

Research output: Contribution to journalArticle

Furans
Diels-Alder reactions
Anhydrides
furans
Cycloaddition Reaction
46 Citations (Scopus)
Murraya
Alkaloids
Cycloaddition
Cycloaddition Reaction
Pedigree
1 Citation (Scopus)

Isolation and characterization of sclerienone c from scleria striatinux

Nyongbela, K. D., Makolo, F. L., Hoye, T. R. & Efange, S. M. N., Jan 23 2016, In : Natural Product Communications. 11, 1, p. 5-6 2 p.

Research output: Contribution to journalArticle

Sesquiterpenes
sesquiterpenoids
Cameroon
Spices
antimalarials
3 Citations (Scopus)

Poly(isoprenecarboxylates) from Glucose via Anhydromevalonolactone

Ball-Jones, N. R., Fahnhorst, G. W. & Hoye, T. R., Oct 18 2016, In : ACS Macro Letters. 5, 10, p. 1128-1131 4 p.

Research output: Contribution to journalArticle

Glucose
Esters
Acids
Molecular weight
Acrylates
12 Citations (Scopus)

Reactions of HDDA-Derived Benzynes with Perylenes: Rapid Construction of Polycyclic Aromatic Compounds

Xu, F., Xiao, X. & Hoye, T. R., Nov 4 2016, In : Organic Letters. 18, 21, p. 5636-5639 4 p.

Research output: Contribution to journalArticle

Polycyclic Compounds
Diels-Alder reactions
aromatic compounds
Aromatic compounds
Cycloaddition Reaction
46 Citations (Scopus)

Reactions of HDDA-Derived Benzynes with Sulfides: Mechanism, Modes, and Three-Component Reactions

Chen, J., Palani, V. & Hoye, T. R., Apr 20 2016, In : Journal of the American Chemical Society. 138, 13, p. 4318-4321 4 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
Sulfides
Betaines
Betaine
Proton transfer
13 Citations (Scopus)

Reactions of Hexadehydro-Diels-Alder (HDDA)-Derived Benzynes with Thioamides: Synthesis of Dihydrobenzothiazino-Heterocyclics

Palani, V., Chen, J. & Hoye, T. R., Dec 16 2016, In : Organic Letters. 18, 24, p. 6312-6315 4 p.

Research output: Contribution to journalLetter

Thioamides
Cycloaddition Reaction
Hydrogen
Atoms
zwitterions
27 Citations (Scopus)

The Hexadehydro-Diels-Alder Cycloisomerization Reaction Proceeds by a Stepwise Mechanism

Wang, T., Niu, D. & Hoye, T. R., Jun 29 2016, In : Journal of the American Chemical Society. 138, 25, p. 7832-7835 4 p.

Research output: Contribution to journalArticle

Alnus
Alkynes
Cycloaddition
Cyclization
Cycloaddition Reaction
20 Citations (Scopus)

The pentadehydro-Diels-Alder reaction

Wang, T., Naredla, R. R., Thompson, S. K. & Hoye, T. R., Apr 28 2016, In : Nature. 532, 7600, p. 484-488 5 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
Alnus
Hydrogen
Nitriles
Alkynes
20 Citations (Scopus)

The Phenol-Ene Reaction: Biaryl Synthesis via Trapping Reactions between HDDA-Generated Benzynes and Phenolics

Zhang, J., Niu, D., Brinker, V. A. & Hoye, T. R., Nov 4 2016, In : Organic Letters. 18, 21, p. 5596-5599 4 p.

Research output: Contribution to journalArticle

Alnus
Phenols
Phenol
phenols
trapping
2015
15 Citations (Scopus)

(+)- and (-)-petromyroxols: Antipodal tetrahydrofurandiols from larval sea lamprey (petromyzon marinus L.) that elicit enantioselective olfactory responses

Li, K., Huertas, M., Brant, C., Chung-Davidson, Y. W., Bussy, U., Hoye, T. R. & Li, W., Jan 16 2015, In : Organic Letters. 17, 2, p. 286-289 4 p.

Research output: Contribution to journalArticle

Petromyzon
Enantiomers
enantiomers
fatty acids
chromatography
13 Citations (Scopus)
Alnus
Cycloaddition Reaction
Data storage equipment
Alkynes
Substrates
23 Citations (Scopus)

Diels-Alderase-free, bis-pericyclic, [4+2] dimerization in the biosynthesis of (±)-paracaseolide A

Wang, T. & Hoye, T. R., Aug 25 2015, In : Nature Chemistry. 7, 8, p. 641-645 5 p.

Research output: Contribution to journalArticle

Dimerization
Biosynthesis
Cycloaddition
Metabolites
Biological Products
1 Citation (Scopus)

Differential cytotoxic activity of the petroleum ether extract and its furanosesquiterpenoid constituents from Commiphora molmol resin

Ayyad, S. E. N., Hoye, T. R., Alarif, W. M., Al Ahmadi, S. M., Basaif, S. A., Ghandourah, M. A. & Badria, F. A., Jan 1 2015, In : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 70, 3-4, p. 87-92 6 p.

Research output: Contribution to journalArticle

Commiphora
Resins
Cells
Trientine
Cell Line
22 Citations (Scopus)

Intramolecular [4 + 2] trapping of a hexadehydro-diels-alder (HDDA) benzyne by tethered arenes

Pogula, V. D., Wang, T. & Hoye, T. R., Feb 20 2015, In : Organic Letters. 17, 4, p. 856-859 4 p.

Research output: Contribution to journalArticle

Methane
trapping
Electrons
rings
adducts
4 Citations (Scopus)

iso-petromyroxols: Novel dihydroxylated tetrahydrofuran enantiomers from sea lamprey (Petromyzon marinus)

Li, K., Brant, C. O., Bussy, U., Pinnamaneni, H., Patel, H., Hoye, T. R. & Li, W., Mar 1 2015, In : Molecules. 20, 3, p. 5215-5222 8 p.

Research output: Contribution to journalArticle

Petromyzon
antipodes
Furans
larvae
Enantiomers
32 Citations (Scopus)

Mechanism of the Intramolecular Hexadehydro-Diels-Alder Reaction

Marell, D. J., Furan, L. R., Woods, B. P., Lei, X., Bendelsmith, A. J., Cramer, C., Hoye, T. R. & Kuwata, K. T., Aug 13 2015, In : Journal of Organic Chemistry. 80, 23, p. 11744-11754 11 p.

Research output: Contribution to journalArticle

Alkynes
Density functional theory
Diynes
Wave functions
Kinetics
13 Citations (Scopus)

Nanoparticles Containing High Loads of Paclitaxel-Silicate Prodrugs: Formulation, Drug Release, and Anticancer Efficacy

Han, J., Michel, A. R., Lee, H., Kalscheuer, S., Wohl, A., Hoye, T. R., McCormick, A. V., Panyam, J. & Macosko, C., Oct 27 2015, In : Molecular pharmaceutics. 12, 12, p. 4329-4335 7 p.

Research output: Contribution to journalArticle

Silicates
Prodrugs
Paclitaxel
Nanoparticles
Hydrophobic and Hydrophilic Interactions