Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Postdoctoral Research in Immunology and Cell Signaling, University of California at San Francisco
Sep 2007 → Jul 2014
PhD, Graduate Research in Molecular and Cell Biology, University of California at Berkeley
Aug 2001 → May 2007
BA, Undergraduate Degree in Biochemistry, Bowdoin College
Aug 1995 → May 1999
Research Interest Keywords
- myeloid cells
- immunology
- autoimmune disease
- tumor micro
- biochemistry
- tyrosine kinase signaling
Fingerprint
The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Functions of LynA and LynB kinases in myeloid-cell pro-inflammatory signaling and lupus
Freedman, T. (PI), Binstadt, B. A. (CoI) & Lipscomb, M. W. (CoI)
NIH NIAMS NATIONALL INSTITUTE OF ARTHRIT
9/1/25 → 8/31/30
Project: Research project
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Lyn kinase and immune function in mammary cancer
Freedman, T. (PI) & Greene, J. T. (Other Role)
12/1/24 → 5/31/26
Project: Research project
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Allosteric mechanisms driving paradoxical activation of RAF kinases
Levinson, N. M. (PI), Freedman, T. (CoI) & Sheedlo, M. J. (CoI)
NATIONAL INSTITUTES OF HEALTH (NIH)
7/1/24 → 6/30/26
Project: Research project
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Functions of LynA and LynB kinases in dendritic- and B-cell inflammatory signaling
Freedman, T. (PI) & Binstadt, B. A. (Co-Principal Investigator)
NIH NIAMS NATIONALL INSTITUTE OF ARTHRIT
9/20/24 → 8/31/25
Project: Research project
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LynB kinase, TLR signaling, dendritic cells, and lupus
Freedman, T. (PI)
RHEUMATOLOGY RESEARCH FOUNDATION
7/1/22 → 6/30/24
Project: Research project
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Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
Brian, B. F., Jolicoeur, A. S., Guerrero, C. R., Nunez, M. G., Sychev, Z. E., Hegre, S. A., Sætrom, P., Habib, N., Drake, J. M., Schwertfeger, K. L. & Freedman, T. S., Jul 2019, In: eLife. 8, e46043.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner
Lindstedt, A. J., Greene, J. T., Xu, Y., Williams, J. W. & Freedman, T. S., Nov 1 2025, In: Journal of Leukocyte Biology. 117, 11, qiaf140.Research output: Contribution to journal › Article › peer-review
Open Access -
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors
Rasmussen, D. M., Semonis, M. M., Greene, J. T., Muretta, J. M., Thompson, A. R., Toledo Ramos, S., Thomas, D. D., Pomerantz, W. C. K., Freedman, T. S. & Levinson, N. M., May 14 2024, In: eLife. 13, 13:RP95481.Research output: Contribution to journal › Article › peer-review
Open Access -
Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells
Matson, A. W., Hullsiek, R., Dixon, K. J., Wang, S., Lindstedt, A. J., Friess, R. R., Phung, S. K., Freedman, T. S., Felices, M., Truckenbrod, E. N., Wu, J., Miller, J. S. & Walcheck, B., Jul 24 2024, In: Journal for ImmunoTherapy of Cancer. 12, 7, e008959.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Primary infection with Zika virus provides one-way heterologous protection against Spondweni virus infection in rhesus macaques
Jaeger, A. S., Crooks, C. M., Weiler, A. M., Bliss, M. I., Rybarczyk, S., Richardson, A., Einwalter, M., Peterson, E., Capuano, S., Barkhymer, A., Becker, J. T., Greene, J. T., Freedman, T. S., Langlois, R. A., Friedrich, T. C. & Aliota, M. T., Jun 2023, In: Science Advances. 9, 26, eadg3444.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations