Projects per year
Personal profile
Expertise related to UN SDGs
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
Sep 2007 → Jul 2014
PhD, UNIVERSITY OF CALIFORNIA, BERKELEY
Aug 2001 → May 2007
BA, Bowdoin College
Aug 1995 → May 1999
Research Interest Keywords
- myeloid cells
- immunology
- autoimmune disease
- tumor micro
- biochemistry
- tyrosine kinase signaling
Fingerprint
The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Projects
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Roles of the Src-family kinases LynA and LynB in macrophage inflammatory signaling
Freedman, T. & Binstadt, B. A.
NIH NIAMS NATL INST OF ARTHRIT
9/1/18 → 8/31/23
Project: Research project
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Generating LynA-/- and LynB-/- mice by CRISPR/Cas9 genom
NIH Nat'l Inst of Allergy & Infect Dis
1/15/17 → 12/31/18
Project: Research project
Research output
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Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
Brian, B. F., Jolicoeur, A. S., Guerrero, C. R., Nunez, M. G., Sychev, Z. E., Hegre, S. A., Sætrom, P., Habib, N., Drake, J. M., Schwertfeger, K. L. & Freedman, T. S., Jul 2019, In: eLife. 8, e46043.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Immunopharmacology and Quantitative Analysis of Tyrosine Kinase Signaling
Brian, B. F., Guerrero, C. R. & Freedman, T. S., Sep 1 2020, In: Current Protocols in Immunology. 130, 1, e104.Research output: Contribution to journal › Article › peer-review
Open Access -
Lessons of COVID-19: A roadmap for post-pandemic science
Freedman, T. S., Headley, M. B., Serwas, N., Ruhland, M., Castellanos, C. A., Combes, A. J. & Krummel, M. F., Sep 7 2020, In: Journal of Experimental Medicine.Research output: Contribution to journal › Editorial
1 Scopus citations -
LynA regulates an inflammation-sensitive signaling checkpoint in macrophages
Freedman, T. S., Tan, Y. X., Skrzypczynska, K. M., Manz, B. N., Sjaastad, F. V., Goodridge, H. S., Lowell, C. A. & Weiss, A., Oct 30 2015, In: eLife. 4, OCTOBER2015, e09183.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling
Tan, Y. X., Manz, B. N., Freedman, T. S., Zhang, C., Shokat, K. M. & Weiss, A., Feb 2014, In: Nature immunology. 15, 2, p. 186-194 9 p.Research output: Contribution to journal › Article › peer-review
63 Scopus citations