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Research Output 2001 2019

2019
1 Citation (Scopus)
Heart-Assist Devices
Angiotensin II
Hemorrhage

Emerging Therapies for Dystrophic Cardiomyopathy

Garry, D. J. & Alexy, T., Nov 2019, In : JACC: Basic to Translational Science. 4, 7, p. 792-794 3 p.

Research output: Contribution to journalEditorial

Open Access
Ribonucleotide Reductases
Dystrophin
Cardiomyopathies
Therapeutics

Ventricular Assist Device Driveline Dressing-Change Protocols: A Need for Standardization. A Report from the SimVAD Investigators

Wilcox, J. E., Cameron, K. A., Harap, R. S., Shanklin, K. L., Grady, K. L., Cohen, E. R., Abicht, T. O., Adler, E. D., Alexy, T., Alonso, W., Beckman, J., Bjelkengren, J., Cagliostro, B., Cogswell, R., Colombo, P. C., Cotts, W., Haglund, N. A., Haverstick, S., Kiernan, M. S., Lampert, B. & 13 others, LeMond, L. M., Lee, S., Lerg, G., Lindenfeld, J., Mahr, C., Meehan, K., Pagani, F. D., Pan, S., Pavone, J., Um, J., Yancy, C. W., Thinh, D. & Barsuk, J. H., Aug 2019, In : Journal of cardiac failure. 25, 8, p. 695-697 3 p.

Research output: Contribution to journalLetter

Heart-Assist Devices
Bandages
Research Personnel
2018
Sodium Potassium Chloride Symporter Inhibitors
Furosemide
Disease Management
Diuretics
Heart Failure

Heart failure with reduced ejection fraction (HFREF)

Alexy, T., Lebeis, T. & Cole, R., Jan 1 2018, Heart Failure: What a Non-Heart Failure Specialist Needs to Know. Nova Science Publishers, Inc., p. 21-49 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Heart Failure
Sodium-Restricted Diet
Obstructive Sleep Apnea
Signs and Symptoms
Life Style

Neurological complications associated with left ventricular assist device therapy

Goodwin, K., Kluis, A., Alexy, T., John, R. & Voeller, R. K., Dec 2 2018, In : Expert Review of Cardiovascular Therapy. 16, 12, p. 909-917 9 p.

Research output: Contribution to journalReview article

Heart-Assist Devices
Stroke
Therapeutics
Manuscripts
Clinical Protocols
2016
1 Citation (Scopus)

Rheumatoid Arthritis Presenting as Acute Myopericarditis

Mitchell, A. J., Alexy, T., Rubinsztain, L., Iqbal, A., Shah, A. J., Maziar Zafari, A. & Searles, C. D., May 1 2016, In : American Journal of Medicine. 129, 5, p. e17-e18

Research output: Contribution to journalArticle

Rheumatoid Arthritis
38 Citations (Scopus)

The role of blood rheology in sickle cell disease

Connes, P., Alexy, T., Detterich, J., Romana, M., Hardy-Dessources, M. D. & Ballas, S. K., Mar 1 2016, In : Blood Reviews. 30, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

Rheology
Sickle Cell Anemia
Hemoglobin SC Disease
Hemorheology
Cell Aggregation
2015
7 Citations (Scopus)

Abnormal blood rheology and chronic low grade inflammation: Possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects

Alexy, T., Pais, E., Wenby, R. B., Mack, W. J., Hodis, H. N., Kono, N., Wang, J., Baskurt, O. K., Fisher, T. C. & Meiselman, H. J., Mar 1 2015, In : Atherosclerosis. 239, 1, p. 248-251 4 p.

Research output: Contribution to journalArticle

Rheology
Coronary Artery Disease
Atherosclerosis
Inflammation
Hemorheology
2014
7 Citations (Scopus)

EPO or PlacEPO? Science versus Practical Experience: Panel discussion on efficacy of erythropoetin in improving performance

Hardeman, M., Alexy, T., Brouwer, B., Connes, P., Jung, F., Kuipers, H. & Baskurt, O. K., Jan 1 2014, In : Biorheology. 51, 2-3, p. 83-90 8 p.

Research output: Contribution to journalArticle

Erythropoietin
Hematocrit
Athletes
Hemoglobins
Hemorheology
2 Citations (Scopus)

Gender differences in hemorheological parameters and in in vitro platelet aggregation in acetylsalicylic acid and clopidogrel treated vascular patients

Koltai, K., Papp, J., Kenyeres, P., Feher, G., Tibold, A., Alexy, T., Marton, Z., Kesmarky, G. & Toth, K., Jan 1 2014, In : Biorheology. 51, 2, p. 197-206 10 p.

Research output: Contribution to journalArticle

clopidogrel
Platelet Aggregation
Aspirin
Blood Vessels
Adenosine Diphosphate
5 Citations (Scopus)

Shear sensitive microRNAs and atherosclerosis

Alexy, T., James, A. M. & Searles, C. D., Jan 1 2014, In : Biorheology. 51, 2-3, p. 147-158 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Atherosclerosis
Developed Countries
Chronic Disease
Arteries
37 Citations (Scopus)

TNF-α alters the release and transfer of microparticle-encapsulated miRNAs from endothelial cells

Alexy, T., Rooney, K., Weber, M., Gray, W. D. & Searles, C. D., Nov 15 2014, In : Physiological genomics. 46, 22, p. 833-840 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Endothelial Cells
rho-Associated Kinases
Caspase Inhibitors
Caspases
2013
19 Citations (Scopus)

Low-shear red blood cell oxygen transport effectiveness is adversely affected by transfusion and further worsened by deoxygenation in sickle cell disease patients on chronic transfusion therapy

Detterich, J., Alexy, T., Rabai, M., Wenby, R., Dongelyan, A., Coates, T., Wood, J. & Meiselman, H., Feb 1 2013, In : Transfusion. 53, 2, p. 297-305 9 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Hematocrit
Viscosity
Erythrocytes
Oxygen
2011
4 Citations (Scopus)

Effect of lanthanides on red blood cell deformability and response to mechanical stress: Role of lanthanide ionic radius

Alexy, T., Baskurt, O. K., Nemeth, N., Uyuklu, M., Wenby, R. B. & Meiselman, H. J., Dec 1 2011, In : Biorheology. 48, 3-4, p. 173-183 11 p.

Research output: Contribution to journalArticle

Lanthanoid Series Elements
Mechanical Stress
Erythrocytes
Lanthanum
Glycocalyx
5 Citations (Scopus)

Reviewing data reduction methods for ektacytometry

Kenyeres, P., Rabai, M., Toth, A., Kesmarky, G., Marton, Z., Alexy, T. & Toth, K., Mar 7 2011, In : Clinical Hemorheology and Microcirculation. 47, 2, p. 143-150 8 p.

Research output: Contribution to journalArticle

Erythrocyte Deformability
Artifacts
Erythrocytes
Weights and Measures
2010
4 Citations (Scopus)

Regulated expansion of human pancreatic β-cells

Pais, E., Park, J., Alexy, T., Nikolian, V., Ge, S., Shaw, K., Senadheera, S., Hardee, C. L., Skelton, D., Hollis, R., Crooks, G. M. & Kohn, D. B., Jul 1 2010, In : Molecular Therapy. 18, 7, p. 1389-1396 8 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Cell Transplantation
Diabetes Mellitus
Ligands
Islets of Langerhans
34 Citations (Scopus)

Sickle cell disease: Selected aspects of pathophysiology

Alexy, T., Sangkatumvong, S., Connes, P., Pais, E., Tripette, J., Barthelemy, J. C., Fisher, T. C., Meiselman, H. J., Khoo, M. C. & Coates, T. D., 2010, In : Clinical hemorheology and microcirculation. 44, 3, p. 155-166 12 p.

Research output: Contribution to journalArticle

Sickle Cell Trait
Sickle Cell Anemia
Rheology
Clinical Pathology
Autonomic Nervous System
2009
4 Citations (Scopus)

A novel high-throughput screening assay for sickle cell disease drug discovery

Pais, E., Cambridge, J. S., Johnson, C. S., Meiselman, H. J., Fisher, T. C. & Alexy, T., Apr 1 2009, In : Journal of Biomolecular Screening. 14, 4, p. 330-336 7 p.

Research output: Contribution to journalArticle

High-Throughput Screening Assays
Sickle Cell Anemia
Drug Discovery
Assays
Screening
8 Citations (Scopus)

A rapid method to estimate Westergren sedimentation rates

Alexy, T., Pais, E. & Meiselman, H. J., Oct 12 2009, In : Review of Scientific Instruments. 80, 9, 096102.

Research output: Contribution to journalArticle

erythrocytes
Sedimentation
estimates
Blood
tubes
43 Citations (Scopus)

Comparison of three commercially available ektacytometers with different shearing geometries

Baskurt, O. K., Hardeman, M. R., Uyuklu, M., Ulker, P., Cengiz, M., Nemeth, N., Shin, S., Alexy, T. & Meiselman, H. J., Aug 19 2009, In : Biorheology. 46, 3, p. 251-264 14 p.

Research output: Contribution to journalArticle

Silver Sulfadiazine
Erythrocytes
Hot Temperature
Korea
Biological Assay
32 Citations (Scopus)

Comparison of three instruments for measuring red blood cell aggregation

Baskurt, O. K., Uyuklu, M., Ulker, P., Cengiz, M., Nemeth, N., Alexy, T., Shin, S., Hardeman, M. R. & Meiselman, H. J., Dec 1 2009, In : Clinical hemorheology and microcirculation. 43, 4, p. 283-298 16 p.

Research output: Contribution to journalArticle

Cell Aggregation
Erythrocytes
Dextrans
Plasma Cells
Biological Assay
28 Citations (Scopus)

Inter-species differences in hematocrit to blood viscosity ratio

Nemeth, N., Alexy, T., Furka, A., Baskurt, O. K., Meiselman, H. J., Furka, I. & Miko, I., Aug 19 2009, In : Biorheology. 46, 2, p. 155-165 11 p.

Research output: Contribution to journalArticle

Blood Viscosity
Hematocrit
Viscosity
Oxygen
Physiological Phenomena
80 Citations (Scopus)

Parameterization of red blood cell elongation index - Shear stress curves obtained by ektacytometry

Baskurt, O. K., Hardeman, M. R., Uyuklu, M., Ulker, P., Cengiz, M., Nemeth, N., Shin, S., Alexy, T. & Meiselman, H. J., Dec 1 2009, In : Scandinavian Journal of Clinical and Laboratory Investigation. 69, 7, p. 777-788 12 p.

Research output: Contribution to journalArticle

Glutaral
Parameterization
Shear stress
Elongation
Blood
91 Citations (Scopus)

Red blood cell aggregation, aggregate strength and oxygen transport potential of blood are abnormal in both homozygous sickle cell anemia and sickle-hemoglobin C disease

Tripette, J., Alexy, T., Hardy-Dessources, M. D., Mougenel, D., Beltan, E., Chalabi, T., Chout, R., Etienne-Julan, M., Hue, O., Meiselman, H. J. & Connes, P., Aug 1 2009, In : Haematologica. 94, 8, p. 1060-1065 6 p.

Research output: Contribution to journalArticle

Hemoglobin C Disease
Sickle Hemoglobin
Cell Aggregation
Sickle Cell Anemia
Erythrocytes
2008
45 Citations (Scopus)

Hemorheological abnormalities in stable angina and acute coronary syndromes

Lee, B. K., Durairaj, A., Mehra, A., Wenby, R. B., Meiselman, H. J. & Alexy, T., Jul 29 2008, In : Clinical hemorheology and microcirculation. 39, 1-4, p. 43-51 9 p.

Research output: Contribution to journalArticle

Stable Angina
Acute Coronary Syndrome
Unstable Angina
Blood Viscosity
Myocardial Infarction
5 Citations (Scopus)

Heparin-platelet factor 4 antibodies are frequent after vascular surgery but are not a frequent cause of graft thrombosis or thrombocytopenia

Alexy, T., Tucker, S., Boyle, S., Rowe, V. L., Weaver, F. A. & Liebman, H. A., Aug 1 2008, In : Journal of vascular surgery. 48, 2, p. 377-381 5 p.

Research output: Contribution to journalArticle

Platelet Factor 4
Thrombocytopenia
Blood Vessels
Heparin
Thrombosis
28 Citations (Scopus)

Microcirculatory dysfunction in cardiac syndrome X: Role of abnormal blood rheology

Lee, B. K., Durairaj, A., Mehra, A., Wenby, R., Meiselman, H. & Alexy, T., Jul 1 2008, In : Microcirculation. 15, 5, p. 451-459 9 p.

Research output: Contribution to journalArticle

Microvascular Angina
Rheology
Cell Aggregation
Blood Viscosity
Erythrocytes
9 Citations (Scopus)

Relation of platelet aggregation and fibrinogen levels to advancing age in aspirin- and thienopyridine-treated patients

Koltai, K., Feher, G., Kenyeres, P., Lenart, I., Alexy, T., Horvath, B., Marton, Z., Kesmarky, G. & Toth, K., Dec 1 2008, In : Clinical hemorheology and microcirculation. 40, 4, p. 295-302 8 p.

Research output: Contribution to journalArticle

Platelet Aggregation
clopidogrel
Fibrinogen
Aspirin
Ticlopidine
2007
7 Citations (Scopus)

Effect of lanthanum on red blood cell deformability

Alexy, T., Nemeth, N., Wenby, R. B., Bauersachs, R. M., Baskurt, O. K. & Meiselman, H. J., Dec 1 2007, In : Biorheology. 44, 5-6, p. 361-373 13 p.

Research output: Contribution to journalArticle

Lanthanum
Erythrocytes
Membranes
Lanthanoid Series Elements
Cell Fusion
4 Citations (Scopus)

Effects of cyclodextrins on RBC aggregation and blood viscosity

Toyama, Y., Pais, E., Meiselman, H. J. & Alexy, T., Mar 5 2007, In : Clinical Hemorheology and Microcirculation. 36, 2, p. 173-180 8 p.

Research output: Contribution to journalArticle

Blood Viscosity
Cyclodextrins
Platelet Aggregation
Blood Platelets
Glucose
28 Citations (Scopus)

Red blood cell aggregation quantitated via Myrenne aggregometer and yield shear stress

Lee, B. K., Alexy, T., Wenby, R. B. & Meiselman, H. J., May 11 2007, In : Biorheology. 44, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Cell Aggregation
Erythrocytes
Suspensions
Validation Studies
Calibration
2006
vinpocetine
Cerebrovascular Circulation
Erythrocyte Aggregation
Vinca Alkaloids
Cerebrovascular Disorders
23 Citations (Scopus)

Effects of nattokinase, a pro-fibrinolytic enzyme, on red blood cell aggregation and whole blood viscosity

Pais, E., Alexy, T., Holsworth, R. E. & Meiselman, H. J., Aug 1 2006, In : Clinical hemorheology and microcirculation. 35, 1-2, p. 139-142 4 p.

Research output: Contribution to journalArticle

Cell Aggregation
Blood Viscosity
Erythrocytes
Soy Foods
Enzymes
1 Citation (Scopus)

Estimation of infused dextran plasma concentration via measurement of plasma viscosity

Ulker, P., Alexy, T., Meiselman, H. J. & Başkurt, O. K., May 18 2006, In : Biorheology. 43, 2, p. 161-166 6 p.

Research output: Contribution to journalArticle

Hemorheology
Erythrocyte Aggregation
Intra Arterial Infusions
Blood Viscosity
Dextrans
36 Citations (Scopus)

Rheologic behavior of sickle and normal red blood cell mixtures in sickle plasma: Implications for transfusion therapy

Alexy, T., Pais, E., Armstrong, J. K., Meiselman, H. J., Johnson, C. S. & Fisher, T. C., Jun 1 2006, In : Transfusion. 46, 6, p. 912-918 7 p.

Research output: Contribution to journalArticle

Hematocrit
Viscosity
Erythrocytes
Cell Communication
Therapeutics
2005
27 Citations (Scopus)

An automated tube-type blood viscometer: Validation studies

Alexy, T., Wenby, R. B., Pais, E., Goldstein, L. J., Hogenauer, W. & Meiselman, H. J., Jun 6 2005, In : Biorheology. 42, 3, p. 237-247 11 p.

Research output: Contribution to journalArticle

Validation Studies
Blood Viscosity
Hematocrit
Temperature
61 Citations (Scopus)

Glycoprotein IIIA (PlA) polymorphism aspirin resistance: Is there any correlation?

Papp, E., Havasi, V., Bene, J., Komlosi, K., Czopf, L., Magyar, E., Feher, C., Feher, G., Horvath, B., Marton, Z., Alexy, T., Habon, T., Szabo, L., Toth, K. & Melegh, B., Jun 1 2005, In : Annals of Pharmacotherapy. 39, 6, p. 1013-1018 6 p.

Research output: Contribution to journalArticle

Acute Coronary Syndrome
Aspirin
Glycoproteins
Alleles
Blood Platelets
10 Citations (Scopus)

Measurement of whole blood viscosity profiles via an automated viscometer: Technical details and clinical relevance

Alexy, T., Pais, E., Wenby, R. B., Hogenauer, W., Toth, K., Meiselman, H. J. & Kensey, K. R., Nov 28 2005, In : Clinical Laboratory. 51, 9-10, p. 523-529 7 p.

Research output: Contribution to journalArticle

Blood Viscosity
Viscometers
Blood
Viscosity
Mechanics
2004
31 Citations (Scopus)

Effects of PACAP on in vitro and in vivo neuronal cell death, platelet aggregation, and production of reactive oxygen radicals

Reglodi, D., Fábián, Z., Tamás, A., Lubics, A., Szeberényi, J., Alexy, T., Tóth, K., Márton, Z., Borsiczky, B., Roth, E., Szalontay, L. & Lengvári, I., Dec 15 2004, In : Regulatory Peptides. 123, 1-3 SPEC. ISS., p. 51-59 9 p.

Research output: Contribution to journalArticle

Pituitary Adenylate Cyclase-Activating Polypeptide
Cell death
Platelets
Platelet Aggregation
Reactive Oxygen Species
39 Citations (Scopus)

Hemorheological disturbances in patients with chronic cerebrovascular diseases

Szapary, L., Horvath, B., Marton, Z., Alexy, T., Demeter, N., Szots, M., Klabuzai, A., Kesmarky, G., Juricskay, I., Gaal, V., Czopf, J. & Toth, K., Aug 30 2004, In : Clinical hemorheology and microcirculation. 31, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Chronic Disease
Cell Aggregation
Stroke
Hematocrit
2 Citations (Scopus)

Hemorheological methods in drug research

Marton, Z., Halmosi, R., Alexy, T., Horvath, B., Toth, A., Feher, G., Koltai, K., Kesmarky, G., Habon, T., Sumegi, B., Hideg, K. & Toth, K., Aug 2 2004, In : Clinical hemorheology and microcirculation. 30, 3-4, p. 243-252 10 p.

Research output: Contribution to journalArticle

Antioxidants
Research
Pharmaceutical Preparations
Vitamin E
Platelet Aggregation
10 Citations (Scopus)

Inhibition of ADP-Evoked Platelet Aggregation by Selected Poly(ADP-Ribose) Polymerase Inhibitors

Alexy, T., Toth, A., Marton, Z., Horvath, B., Koltai, K., Feher, G., Kesmarky, G., Kalai, T., Hideg, K., Sumegi, B. & Toth, K., Mar 1 2004, In : Journal of Cardiovascular Pharmacology. 43, 3, p. 423-431 9 p.

Research output: Contribution to journalArticle

Platelet Aggregation
Adenosine Diphosphate
Blood Platelets
Epinephrine
Heparin
38 Citations (Scopus)

Measurement of von Willebrand factor as the marker of endothelial dysfunction in vascular diseases

Horvath, B., Hegedus, D., Szapary, L., Marton, Z., Alexy, T., Koltai, K., Czopf, L., Wittmann, I., Juricskay, I., Toth, K. & Kesmarky, G., Jun 24 2004, In : Experimental and Clinical Cardiology. 9, 1, p. 31-34 4 p.

Research output: Contribution to journalArticle

von Willebrand Factor
Vascular Diseases
Acute Coronary Syndrome
Stroke
Blood Vessels
41 Citations (Scopus)

Short-Term Effect of Low-Dose Atorvastatin on Haemorrheological Parameters, Platelet Aggregation and Endothelial Function in Patients with Cerebrovascular Disease and Hyperlipidaemia

Szapary, L., Horvath, B., Marton, Z., Alexy, T., Kesmarky, G., Habon, T., Szots, M., Koltai, K., Juricskay, I., Czopf, J. & Toth, K., Mar 15 2004, In : CNS Drugs. 18, 3, p. 165-172 8 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Hyperlipidemias
Platelet Aggregation
Therapeutics
Hydroxymethylglutaryl-CoA Reductase Inhibitors
4 Citations (Scopus)

Short-term effects of atorvastatin on haemorheologic parameters, platelet aggregation and endothelium dysfunction in patients with hypercholesterolaemia [1]

Horvath, B., Marton, Z., Alexy, T., Kesmarky, G., Toth, K. & Szapary, L., Jan 1 2004, In : European Heart Journal. 25, 1, 1 p.

Research output: Contribution to journalLetter

Heptanoic Acids
Anticholesteremic Agents
Pyrroles
Hypercholesterolemia
Platelet Aggregation
2003
6 Citations (Scopus)

A kardiovaszkuláris rizikófaktorok hatása az agyérbetegek hemoreológiai viszonyaira.

Translated title of the contribution: Effects of cardiovascular risk factors on hemorheologic parameters in cerebrovascular patientsSzapáry, L., Szóts, M., Horváth, B., Márton, Z., Alexy, T., Késmárky, G., Juricskay, I., Nagy, F., Gaál, V., Pálfi, A., Koltai, K. & Tóth, K., Jan 1 2003, In : Orvosi Hetilap. 144, 22, p. 1085-1090 6 p.

Research output: Contribution to journalArticle

Hematocrit
Viscosity
Fibrinogen
Cerebrovascular Disorders
Stroke
3 Citations (Scopus)

A von Willebrand-faktornak, mint az endothelium diszfunkció markerének vizsgálata érbetegekben.

Translated title of the contribution: Investigation of von Willebrand-factor as a marker of endothelial dysfunction in atherosclerotic patientsHorváth, B., Hegedüs, D., Szapáry, L., Márton, Z., Alexy, T., Koltai, K., Gyevnár, Z., Juricskay, I., Tóth, K. & Késmárky, G., Dec 14 2003, In : Orvosi Hetilap. 144, 50, p. 2471-2476 6 p.

Research output: Contribution to journalArticle

von Willebrand Factor
Vascular Diseases
Troponin
Acute Coronary Syndrome
Endothelium
26 Citations (Scopus)

Follow-up of hemorheological parameters and platelet aggregation in patients with acute coronary syndromes

Marton, Z., Horvath, B., Alexy, T., Kesmarky, G., Gyevnar, Z., Czopf, L., Habon, T., Kovacs, L., Papp, E., Mezey, B., Roth, E., Juricskay, I. & Toth, K., Dec 11 2003, In : Clinical Hemorheology and Microcirculation. 29, 2, p. 81-94 14 p.

Research output: Contribution to journalArticle

Acute Coronary Syndrome
Platelet Aggregation
Blood Viscosity
Myocardial Ischemia
Cell Aggregation
9 Citations (Scopus)

Vinpocetin hatása krónikus agyérbetegségben szenvedók hemoreológiai viszonyaira.

Translated title of the contribution: Effect of vinpocetin on the hemorheologic parameters in patients with chronic cerebrovascular diseaseSzapáry, L., Horváth, B., Alexy, T., Márton, Z., Késmárky, G., Szóts, M., Nagy, F., Czopf, J. & Tóth, K., Jan 1 2003, In : Orvosi Hetilap. 144, 20, p. 973-978 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
vinpocetine
Chronic Disease
Cell Aggregation
Therapeutics