Projects per year
Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
- 13 Similar Profiles
Amyloid
Medicine & Life Sciences
Alzheimer Disease
Medicine & Life Sciences
Amyloid Plaques
Medicine & Life Sciences
Transforming Growth Factors
Medicine & Life Sciences
Brain
Medicine & Life Sciences
Transgenic Mice
Medicine & Life Sciences
Amyloid beta-Protein Precursor
Medicine & Life Sciences
Memory Disorders
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2008 2024
Role of alpha-synuclein dependent network hyperexcitability in Lewy Body Dementia
NIH NAT INST OF NEURO DISORDERS & STROKE
9/15/19 → 7/31/20
Project: Research project
Lewy Body Disease
alpha-Synuclein
Soluble aSyn is a modulator of AD pathophysiology
Lesne, S. E., Araque, A. & Lee, M. K.
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/19 → 3/31/24
Project: Research project
AMP-Kinase as a target for neuroprotection in AD
Lee, M. K., Lesne, S. E. & Liao, D.
NIH NAT'L INSTITUTE ON AGING (NIA)
2/15/19 → 1/31/24
Project: Research project
Adenylate Kinase
Neuroprotection
Klotho and Neurodegenerative Disease
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
4/1/16 → 3/31/21
Project: Research project
Neurodegenerative Diseases
Research Output 2000 2019
2
Citations
(Scopus)
Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy
Singh, B., Covelo, A., Martell-Martínez, H., Nanclares, C., Sherman, M. A., Okematti, E., Meints, J., Teravskis, P. J., Gallardo, C., Savonenko, A. V., Benneyworth, M. A., Lesne, S. E., Liao, D., Araque, A. & Lee, M. K., Oct 1 2019, In : Acta Neuropathologica. 138, 4, p. 551-574 24 p.Research output: Contribution to journal › Article
Memory Disorders
Transgenic Mice
Lewy Body Disease
Parkinson Disease
Dementia
4
Citations
(Scopus)
Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons
Khan, S. S., LaCroix, M., Boyle, G., Sherman, M. A., Brown, J. L., Amar, F., Aldaco, J., Lee, M. K., Bloom, G. S. & Lesne, S. E., Oct 1 2018, In : Acta Neuropathologica. 136, 4, p. 589-605 17 p.Research output: Contribution to journal › Article
Open Access
Synucleins
Phenotype
Neurons
Alzheimer Disease
Amyloid
4
Citations
(Scopus)
Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis
Chiang, A. C. A., Fowler, S. W., Reddy, R., Pletnikova, O., Troncoso, J. C., Sherman, M. A., Lesne, S. E. & Jankowsky, J. L., Mar 1 2018, In : American Journal of Pathology. 188, 3, p. 739-756 18 p.Research output: Contribution to journal › Article
Open Access
Amyloidosis
Amyloid
Detergents
Trans-Activators
Amyloid beta-Protein Precursor
20
Citations
(Scopus)
Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits
Larson, M. E., Greimel, S. J., Amar, F., LaCroix, M., Boyle, G., Sherman, M. A., Schley, H., Miel, C., Schneider, J. A., Kayed, R., Benfenati, F., Lee, M. K., Bennett, D. A. & Lesné, S. E., Jun 6 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 23, p. E4648-E4657Research output: Contribution to journal › Article
Open Access
Synucleins
Synapsins
Memory Disorders
Amyloidogenic Proteins
Brain
27
Citations
(Scopus)
The amyloid-β oligomer Aβ∗56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation
Amar, F., Sherman, M. A., Rush, T., Larson, M., Boyle, G., Chang, L., Götz, J., Buisson, A. & Lesne, S. E., May 9 2017, In : Science signaling. 10, 478, aal2021.Research output: Contribution to journal › Article
Open Access
Phosphorylation
Oligomers
Amyloid
Alzheimer Disease
Agglomeration