Projects per year
Personal profile
Expertise related to UN SDGs
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Projects
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Senescence in Parkinson's disease and related disorders
Lee, M. K., Lesne, S. E. & Robbins, P. D.
MICHAEL J. FOX FDN FOR PARKINSON'S RES.
10/1/20 → 9/30/23
Project: Research project
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Alpha-synculein/tau coupling in Alzheimer's disease
NIH NAT'L INSTITUTE ON AGING (NIA)
2/1/20 → 1/31/22
Project: Research project
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Gender-specific alterations of synuclein isoforms in aging and Alzheimer's disease-related dementias
Winston & Maxine Wallin Neuro Disc Fund
1/1/20 → 12/31/21
Project: Research project
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Role of alpha-synuclein dependent network hyperexcitability in Lewy Body Dementia
NIH NAT INST OF NEURO DISORDERS & STROKE
9/15/19 → 7/31/21
Project: Research project
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Soluble aSyn is a modulator of AD pathophysiology
Lesne, S. E., Araque, A. & Lee, M. K.
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/19 → 3/31/24
Project: Research project
Research output
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Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talk
Kayed, R., Dettmer, U. & Lesné, S. E., 2020, In: Journal of Parkinson's Disease. 10, 3, p. 791-818 28 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy
Singh, B., Covelo, A., Martell-Martínez, H., Nanclares, C., Sherman, M. A., Okematti, E., Meints, J., Teravskis, P. J., Gallardo, C., Savonenko, A. V., Benneyworth, M. A., Lesne, S. E., Liao, D., Araque, A. & Lee, M. K., Oct 1 2019, In: Acta Neuropathologica. 138, 4, p. 551-574 24 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons
Khan, S. S., LaCroix, M., Boyle, G., Sherman, M. A., Brown, J. L., Amar, F., Aldaco, J., Lee, M. K., Bloom, G. S. & Lesné, S. E., Oct 1 2018, In: Acta Neuropathologica. 136, 4, p. 589-605 17 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis
Chiang, A. C. A., Fowler, S. W., Reddy, R., Pletnikova, O., Troncoso, J. C., Sherman, M. A., Lesne, S. E. & Jankowsky, J. L., Mar 2018, In: American Journal of Pathology. 188, 3, p. 739-756 18 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits
Larson, M. E., Greimel, S. J., Amar, F., LaCroix, M., Boyle, G., Sherman, M. A., Schley, H., Miel, C., Schneider, J. A., Kayed, R., Benfenati, F., Lee, M. K., Bennett, D. A. & Lesné, S. E., Jun 6 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 23, p. E4648-E4657Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations