Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Regulation of human tau expression and tauopathy by alpha-synuclein
NIH NAT'L INSTITUTE ON AGING (NIA)
6/1/22 → 3/31/27
Project: Research project
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Decision-making alterations in mouse models of Alzheimer's disease
Lesne, S. E., Lind, E. B. & Redish, D.
NIH NAT'L INSTITUTE ON AGING (NIA)
3/1/21 → 2/29/24
Project: Research project
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Alpha-synculein/tau coupling in Alzheimer's disease
NIH NAT'L INSTITUTE ON AGING (NIA)
2/1/20 → 1/31/24
Project: Research project
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Soluble aSyn is a modulator of AD pathophysiology
Lesne, S. E., Araque, A. & Lee, M. K.
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/19 → 3/31/24
Project: Research project
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AMP-Kinase as a target for neuroprotection in AD
Lee, M. K., Lesne, S. E. & Liao, D.
NIH NAT'L INSTITUTE ON AGING (NIA)
2/15/19 → 1/31/24
Project: Research project
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Comment on “Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice”
Brown, J. L., Murphy, K. A., O'Connell, T. D. & Lesné, S. E., Oct 1 2022, In: Journal of Immunology. 209, 7, p. 1229-1233 5 p.Research output: Contribution to journal › Letter › peer-review
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Erratum: Soluble a-Synuclein Is a Novel Modulator of Alzheimer’s Disease Pathophysiology (Journal of Neuroscience (10253–10266) DOI: 10.1523/JNEUROSCI.0581-12.2012)
Larson, M. E., Sherman, M. A., Greimel, S. J., Kuskowski, M. A., Schneider, J. A., Bennett, D. A. & Lesne, S. E., Jun 15 2022, In: Journal of Neuroscience. 42, 24, p. 4953-4955 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex
Brown, J. L., Hart, D. W., Boyle, G. E., Brown, T. G., LaCroix, M., Baraibar, A. M., Pelzel, R., Kim, M., Sherman, M. A., Boes, S., Sung, M., Cole, T., Lee, M. K., Araque, A. & Lesné, S. E., Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 180.Research output: Contribution to journal › Article › peer-review
Open Access -
Amyloid oligomers: A joint experimental/computational perspective on Alzheimer's disease, Parkinson's disease, type II diabetes, and amyotrophic lateral sclerosis
Nguyen, P. H., Ramamoorthy, A., Sahoo, B. R., Zheng, J., Faller, P., Straub, J. E., Dominguez, L., Shea, J. E., Dokholyan, N. V., de Simone, A., Ma, B., Nussinov, R., Najafi, S., Ngo, S. T., Loquet, A., Chiricotto, M., Ganguly, P., McCarty, J., Li, M. S., Hall, C., & 14 others , Feb 24 2021, In: Chemical Reviews. 121, 4, p. 2545-2647 103 p.Research output: Contribution to journal › Review article › peer-review
326 Scopus citations -
Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talk
Kayed, R., Dettmer, U. & Lesné, S. E., 2020, In: Journal of Parkinson's Disease. 10, 3, p. 791-818 28 p.Research output: Contribution to journal › Review article › peer-review
Open Access36 Scopus citations