20022019

Research output per year

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Research Output

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Article

Acquired Tamoxifen Resistance in MCF-7 Breast Cancer Cells Requires Hyperactivation of eIF4F-Mediated Translation

Fagan, D. H., Fettig, L. M., Avdulov, S., Beckwith, H., Peterson, M. S., Ho, Y. Y., Wang, F., Polunovsky, V. A. & Yee, D., Aug 1 2017, In : Hormones and Cancer. 8, 4, p. 219-229 11 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

Avdulov, S., Li, S., Michalek, V., Burrichter, D., Peterson, M., Perlman, D. M., Manivel, J. C., Sonenberg, N., Yee, D., Bitterman, P. B. & Polunovsky, V. A., Jun 1 2004, In : Cancer Cell. 5, 6, p. 553-563 11 p.

Research output: Contribution to journalArticle

270 Scopus citations

Amplified in Breast Cancer Regulates Transcription and Translation in Breast Cancer Cells

Ochnik, A. M., Peterson, M. S., Avdulov, S. V., Oh, A. S., Bitterman, P. B. & Yee, D., 2016, In : Neoplasia. 18, 2, p. 100-110 11 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Chronic Obstructive Pulmonary Disease Phenotype Dictates Cancer-Promoting Stromal Gene Expression Programs

Wendt, C. H., Sandri, B. J., Masvidal, L., Murie, C., Bartish, M., Avdulov, S. V., Higgins, L., Markowski, T., Peterson, M., Bergh, J., Yang, P., Rolny, C., Limper, A. H., Griffin, T. J., Bitterman, P. B. & Larsson, O., Dec 1 2018, In : Annals of the American Thoracic Society. 15, 4, p. S290-S291

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Distinct cancer-promoting stromal gene expression depending on lung function

Sandri, B. J., Masvidal, L., Murie, C., Bartish, M., Avdulov, S., Higgins, L. A., Markowski, T., Peterson, M., Bergh, J., Yang, P., Rolny, C., Limper, A. H., Griffin, T. J., Bitterman, P. B., Wendt, C. H. & Larsson, O., Aug 1 2019, In : American journal of respiratory and critical care medicine. 200, 3, p. 348-358 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

EIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells

Avdulov, S. V., Herrera, J., Smith, K., Peterson, M., Gomez-Garcia, J., Beadnell, T. C., Schwertfeger, K., Benyumov, A., Manivel, J. C., Li, S., Bielinsky, A. K., Yee, D., Bitterman, P. B. & Polunovsky, V. A., Feb 15 2015, In : Cancer Research. 75, 4, p. 687-697 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Eukaryotic translation initiation factor 4E-induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors

Larsson, O., Li, S., Issaenko, O. A., Avdulov, S., Peterson, M., Smith, K., Bitterman, P. B. & Polunovsky, V. A., Jul 15 2007, In : Cancer Research. 67, 14, p. 6814-6824 11 p.

Research output: Contribution to journalArticle

113 Scopus citations

Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein

Ghosh, P., Cheng, J., Chou, T. F., Jia, Y., Avdulov, S., Bitterman, P. B., Polunovsky, V. A. & Wagner, C. R., Aug 2008, In : Protein Expression and Purification. 60, 2, p. 132-139 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hepatocyte nuclear factor-1β regulates urinary concentration and response to hypertonicity

Aboudehen, K., Noureddine, L., Cobo-Stark, P., Avdulov, S., Farahani, S., Gearhart, M. D., Bichet, D. G., Pontoglio, M., Patel, V. & Igarashi, P., Oct 2017, In : Journal of the American Society of Nephrology. 28, 10, p. 2887-2900 14 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling

Aboudehen, K., Farahani, S., Kanchwala, M., Chan, S. C., Avdulov, S., Mickelson, A., Lee, D., Gearhart, M. D., Patel, V., Xing, C. & Igarashi, P., Jun 15 2018, In : Journal of Biological Chemistry. 293, 24, p. 9388-9398 11 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Mechanism of fibrosis in HNF1B-related autosomal dominant tubulointerstitial kidney disease

Chan, S. C., Zhang, Y., Shao, A., Avdulov, S., Herrera, J., Aboudehen, K., Pontoglio, M. & Igarashi, P., Oct 2018, In : Journal of the American Society of Nephrology. 29, 10, p. 2493-2509 17 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Multi-omic molecular profiling of lung cancer in COPD

Sandri, B. J., Kaplan, A., Hodgson, S. W., Peterson, M., Avdulov, S. V., Higgins, L., Markowski, T., Yang, P., Limper, A. H., Griffin, T. J., Bitterman, P. B., Lock, E. & Wendt, C. H., Jul 1 2018, In : European Respiratory Journal. 52, 1, 1702665.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation

Ghosh, B., Benyumov, A., Ghosh, P., Jia, Y., Avdulov, S. V., Dahlberg, P. S., Peterson, M., Smith, K., Polunovsky, V. A., Bitterman, P. B. & Wagner, C. R., May 15 2009, In : ACS Chemical Biology. 4, 5, p. 367-377 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

Xia, H., Diebold, D., Nho, R., Perlman, D., Kleidon, J., Kahm, J., Avdulov, S., Peterson, M., Nerva, J., Bitterman, P. & Henke, C., Jul 7 2008, In : Journal of Experimental Medicine. 205, 7, p. 1659-1672 14 p.

Research output: Contribution to journalArticle

151 Scopus citations

Repression of cap-dependent translation attenuates the transformed phenotype in non-small cell lung cancer both in vitro and in vivo

Jacobson, B. A., Alter, M. D., Kratzke, M. G., Frizelle, S. P., Zhang, Y., Peterson, M. S., Avdulov, S., Mohorn, R. P., Whitson, B. A., Bitterman, P. B., Polunovsky, V. A. & Kratzke, R. A., Apr 15 2006, In : Cancer Research. 66, 8, p. 4256-4262 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E

Smith, K. A., Zhou, B., Avdulov, S., Benyumov, A., Peterson, M., Liu, Y., Okon, A., Hergert, P., Braziunas, J., Wagner, C. R., Borok, Z. & Bitterman, P. B., Dec 18 2015, In : Scientific reports. 5, 18233.

Research output: Contribution to journalArticle

22 Scopus citations

Translational control of cell fate: Availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency

Li, S., Sonenberg, N., Gingras, A. C., Peterson, M., Avdulov, S. V., Polunovsky, V. A. & Bitterman, P. B., 2002, In : Molecular and cellular biology. 22, 8, p. 2853-2861 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release

Li, S., Takasu, T., Perlman, D. M., Peterson, M. S., Burrichter, D., Avdulov, S. V., Bitterman, P. B. & Polunovsky, V. A., Jan 31 2003, In : Journal of Biological Chemistry. 278, 5, p. 3015-3022 8 p.

Research output: Contribution to journalArticle

96 Scopus citations

Translation initiation factor 4E blocks endoplasmic reticulum-mediated apoptosis

Li, S., Perlman, D. M., Peterson, M. S., Burrichter, D., Avdulov, S. V., Polunovsky, V. A. & Bitterman, P. B., May 14 2004, In : Journal of Biological Chemistry. 279, 20, p. 21312-21317 6 p.

Research output: Contribution to journalArticle

39 Scopus citations