1986 …2019
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Research Output 1986 2019

  • 55 Article
  • 7 Review article
  • 1 Chapter
  • 1 Conference contribution
2019
3 Citations (Scopus)

In vivo activity and low toxicity of the second-generation antimicrobial peptide DGL13K

Gorr, S. U., Flory, C. M. & Schumacher, R. J., May 1 2019, In : PloS one. 14, 5, e0216669.

Research output: Contribution to journalArticle

Open Access
antimicrobial peptides
Galleria mellonella
Toxicity
peptides
toxicity
2018
6 Citations (Scopus)
Open Access
Streptococcus gordonii
Enantiomers
Enterococcus faecalis
antimicrobial peptides
enantiomers
2017
97 Citations (Scopus)

Antimicrobial Peptides: Mechanisms of Action and Resistance

Bechinger, B. & Gorr, S. U., Mar 1 2017, In : Journal of dental research. 96, 3, p. 254-260 7 p.

Research output: Contribution to journalReview article

Open Access
Peptides
Antimicrobial Cationic Peptides
Proteins
Cell Membrane
Cell Wall
9 Citations (Scopus)

Solution and Solid-State Nuclear Magnetic Resonance Structural Investigations of the Antimicrobial Designer Peptide GL13K in Membranes

Harmouche, N., Aisenbrey, C., Porcelli, F., Xia, Y., Nelson, S. E., Chen, X., Raya, J., Vermeer, L., Aparicio, C., Veglia, G., Gorr, S-U. & Bechinger, B., Aug 15 2017, In : Biochemistry. 56, 32, p. 4269-4278 10 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Membranes
Peptides
Conformations
2014
52 Citations (Scopus)
Streptococcus gordonii
antimicrobial peptides
Biofilms
biofilm
coatings
2013
40 Citations (Scopus)

Antimicrobial peptide GL13K is effective in reducing biofilms of Pseudomonas aeruginosa

Hirt, H. & Gorr, S. U., Oct 1 2013, In : Antimicrobial agents and chemotherapy. 57, 10, p. 4903-4910 8 p.

Research output: Contribution to journalArticle

Biofilms
Pseudomonas aeruginosa
Peptides
Bacteria
Tobramycin
27 Citations (Scopus)

Antimicrobial properties and dentin bonding strength of magnesium phosphate cements

Mestres, G., Abdolhosseini, M., Bowles, W. R., Huang, S. H., Aparicio, C., Gorr, S-U. & Ginebra, M. P., Sep 1 2013, In : Acta Biomaterialia. 9, 9, p. 8384-8393 10 p.

Research output: Contribution to journalArticle

Dentin
Magnesium
Cements
Phosphates
Pulp Capping and Pulpectomy Agents
82 Citations (Scopus)

Bio-inspired stable antimicrobial peptide coatings for dental applications

Holmberg, K. V., Abdolhosseini, M., Li, Y., Chen, X., Gorr, S-U. & Aparicio, C., Sep 1 2013, In : Acta Biomaterialia. 9, 9, p. 8224-8231 8 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Titanium
Peptides
Orthopedics
Tooth
31 Citations (Scopus)

Membrane selectivity and biophysical studies of the antimicrobial peptide GL13K

Balhara, V., Schmidt, R., Gorr, S. U. & Dewolf, C., Jul 3 2013, In : Biochimica et Biophysica Acta - Biomembranes. 1828, 9, p. 2193-2203 11 p.

Research output: Contribution to journalArticle

Liposomes
Interferometry
Membranes
Peptides
Polarization
2012
45 Citations (Scopus)

Antimicrobial peptides in periodontal innate defense

Gorr, S-U., Nov 30 2012, Periodontal Disease. Kinane, D. F. & Mombelli, A. (eds.). p. 84-98 15 p. (Frontiers of Oral Biology; vol. 15).

Research output: Chapter in Book/Report/Conference proceedingChapter

Periodontal Diseases
Peptides
Proteins
Salivary Proteins and Peptides
Biofilms
21 Citations (Scopus)

Human parotid secretory protein is a lipopolysaccharide-binding protein: Identification of an anti-inflammatory peptide domain

Abdolhosseini, M., Sotsky, J. B., Shelar, A. P., Joyce, P. B. M. & Gorr, S-U., Jan 1 2012, In : Molecular and Cellular Biochemistry. 359, 1-2, p. 1-8 8 p.

Research output: Contribution to journalArticle

Anti-Inflammatory Agents
Peptides
Proteins
Lipopolysaccharides
Nasal Mucosa
23 Citations (Scopus)

Lysine substitutions convert a bacterial-agglutinating peptide into a bactericidal peptide that retains anti-lipopolysaccharide activity and low hemolytic activity

Abdolhosseini, M., Nandula, S. R., Song, J., Hirt, H. & Gorr, S-U., Jun 1 2012, In : Peptides. 35, 2, p. 231-238 8 p.

Research output: Contribution to journalArticle

Lysine
Lipopolysaccharides
Substitution reactions
Peptides
Bacteria
22 Citations (Scopus)

Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model

Horvath, S., Nazmul-Hossain, A. N. M., Pollard, R. P. E., Kroese, F. G. M., Vissink, A., Kallenberg, C. G. M., Spijkervet, F. K. L., Bootsma, H., Michie, S. A., Gorr, S. U., Peck, A. B., Cai, C., Zhou, H. & Wong, D. T. W., Nov 1 2012, In : Arthritis Research and Therapy. 14, 6, R238.

Research output: Contribution to journalArticle

Systems Analysis
Salivary Glands
Systems Biology
Sjogren's Syndrome
Inbred NOD Mouse
7 Citations (Scopus)

Text-mining applied to autoimmune disease research: The Sjögrens syndrome knowledge base

Gorr, S-U., Wennblom, T. J., Horvath, S., Wong, D. T. W. & Michie, S. A., Jul 5 2012, In : BMC Musculoskeletal Disorders. 13, 119.

Research output: Contribution to journalArticle

Data Mining
Knowledge Bases
Autoimmune Diseases
Research
Databases
2011
83 Citations (Scopus)

Antimicrobial peptides and periodontal disease

Gorr, S-U. & Abdolhosseini, M., Mar 1 2011, In : Journal of clinical periodontology. 38, SUPPL. 11, p. 126-141 16 p.

Research output: Contribution to journalArticle

Periodontal Diseases
Peptides
Gingival Crevicular Fluid
Proteins
Saliva
22 Citations (Scopus)

Dual host-defence functions of SPLUNC2/PSP and synthetic peptides derived from the protein

Gorr, S. U., Abdolhosseini, M., Shelar, A. & Sotsky, J., Aug 1 2011, In : Biochemical Society transactions. 39, 4, p. 1028-1032 5 p.

Research output: Contribution to journalArticle

Peptides
Bacteria
Proteins
Anti-Inflammatory Agents
Macrophages
8 Citations (Scopus)

Hydrophobic oxime ethers: A versatile class of pDNA and siRNA transfection lipids

Biswas, S., Knipp, R. J., Gordon, L. E., Nandula, S. R., Gorr, S. U., Clark, G. J. & Nantz, M. H., Nov 4 2011, In : ChemMedChem. 6, 11, p. 2063-2069 7 p.

Research output: Contribution to journalArticle

Oximes
Ethers
Small Interfering RNA
Transfection
Lipids
2009
107 Citations (Scopus)

Antimicrobial peptides of the oral cavity

Gorr, S. U., Oct 1 2009, In : Periodontology 2000. 51, 1, p. 152-180 29 p.

Research output: Contribution to journalArticle

Mouth Diseases
Antimicrobial Cationic Peptides
Gingival Crevicular Fluid
Periodontal Diseases
Anti-Infective Agents
55 Citations (Scopus)

Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands

Hu, S., Zhou, M., Jiang, J., Wang, J., Elashoff, D., Gorr, S., Michie, S. A., Spijkervet, F. K. L., Bootsma, H., Kallenberg, C. G. M., Vissink, A., Horvath, S. & Wong, D. T., Jan 1 2009, In : Arthritis and Rheumatism. 60, 1, p. 81-92 12 p.

Research output: Contribution to journalArticle

Marginal Zone B-Cell Lymphoma
Systems Biology
Parotid Gland
Genes
Gene Regulatory Networks
2008
34 Citations (Scopus)

Design of bacteria-agglutinating peptides derived from parotid secretory protein, a member of the bactericidal/permeability increasing-like protein family

Gorr, S. U., Sotsky, J. B., Shelar, A. P. & Demuth, D. R., Dec 1 2008, In : Peptides. 29, 12, p. 2118-2127 10 p.

Research output: Contribution to journalArticle

Bacteria
Agglutination
Peptides
Proteins
Pseudomonas aeruginosa
53 Citations (Scopus)

P. gingivalis interactions with epithelial cells

Kinane, D. F., Galicia, J. C., Gorr, S. U., Stathopoulou, P. G. & Benakanakere, M., May 2 2008, In : Frontiers in Bioscience. 13, 3, p. 966-984 19 p.

Research output: Contribution to journalReview article

Epithelial Cells
Biofilms
Bacteria
Tooth
Tooth Loss
5 Citations (Scopus)

Secretory cargo composition affects polarized secretion in MDCK epithelial cells

Fasciotto, B. H., Kühn, U., Cohn, D. V. & Gorr, S. U., Mar 1 2008, In : Molecular and cellular biochemistry. 310, 1-2, p. 67-75 9 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Epithelial Cells
Chromogranin A
Sorting
Parathyroid Hormone
2007
49 Citations (Scopus)

Human variability in innate immunity

Kinane, D. F., Demuth, D. R., Gorr, S. U., Hajishengallis, G. N. & Martin, M. H., Oct 1 2007, In : Periodontology 2000. 45, 1, p. 14-34 21 p.

Research output: Contribution to journalArticle

Antimicrobial Cationic Peptides
Porphyromonas gingivalis
Toll-Like Receptors
Periodontitis
Disease Susceptibility
10 Citations (Scopus)

Isoproterenol increases sorting of parotid gland cargo proteins to the basolateral pathway

Venkatesh, S. G., Tan, J., Gorr, S. U. & Darling, D. S., Aug 1 2007, In : American Journal of Physiology - Cell Physiology. 293, 2, p. C558-C565

Research output: Contribution to journalArticle

Parotid Gland
Isoproterenol
Secretory Vesicles
Proteins
Protein Transport
2005
35 Citations (Scopus)

Design and validation of anti-inflammatory peptides from human parotid secretory protein

Geetha, C., Venkatesh, S. G., Bingle, L., Bingle, C. D. & Gorr, S. U., Feb 1 2005, In : Journal of Dental Research. 84, 2, p. 149-153 5 p.

Research output: Contribution to journalArticle

Anti-Inflammatory Agents
Peptides
Proteins
Lipopolysaccharides
human BPIFA2 protein
80 Citations (Scopus)

Parotid secretory granules: Crossroads of secretory pathways and protein storage

Gorr, S. U., Venkatesh, S. G. & Darling, D. S., Jun 1 2005, In : Journal of dental research. 84, 6, p. 500-509 10 p.

Research output: Contribution to journalReview article

Secretory Pathway
Secretory Vesicles
Salivary Proteins and Peptides
Proteins
Acinar Cells
30 Citations (Scopus)

Parotid secretory protein is expressed and inducible in human gingival keratinocytes

Shiba, H., Venkatesh, S. G., Gorr, S. U., Barbieri, G., Kurihara, H. & Kinane, D. F., Apr 1 2005, In : Journal of Periodontal Research. 40, 2, p. 153-157 5 p.

Research output: Contribution to journalArticle

Keratinocytes
Porphyromonas gingivalis
Proteins
Fluorescent Antibody Technique
Real-Time Polymerase Chain Reaction
2004
10 Citations (Scopus)
Parotid Gland
Secretory Vesicles
Pancreas
Amylases
Proteins
73 Citations (Scopus)

Host defense in oral and airway epithelia: Chromosome 20 contributes a new protein family

Bingle, C. D. & Gorr, S. U., Nov 1 2004, In : International Journal of Biochemistry and Cell Biology. 36, 11, p. 2144-2152 9 p.

Research output: Contribution to journalReview article

Chromosomes, Human, Pair 20
Chromosomes
Nasal Mucosa
Epithelium
Palate
2003
47 Citations (Scopus)

Expression and anti-bacterial activity of human parotid secretory protein (PSP)

Geetha, C., Venkatesh, S. G., Dunn, B. H. F. & Gorr, S. U., Aug 1 2003, In : Biochemical Society transactions. 31, 4, p. 815-818 4 p.

Research output: Contribution to journalArticle

Proteins
Parotid Gland
Saliva
Rats
human BPIFA2 protein
54 Citations (Scopus)

Secretory granule biogenesis and chromogranin A: Master gene, on/off switch or assembly factor?

Day, R. & Gorr, S. U., Jan 1 2003, In : Trends in Endocrinology and Metabolism. 14, 1, p. 10-13 4 p.

Research output: Contribution to journalReview article

Switch Genes
Chromogranin A
Secretory Vesicles
Proteins
Endocrine Cells
2002
14 Citations (Scopus)

A sulfated proteoglycan is necessary for storage of exocrine secretory proteins in the rat parotid gland

Venkatesh, S. G. & Gorr, S. U., Jul 30 2002, In : American Journal of Physiology - Cell Physiology. 283, 2 52-2, p. C438-C445

Research output: Contribution to journalArticle

Parotid Gland
Proteoglycans
Rats
Sorting
Proteins
2 Citations (Scopus)
Cells
Pathway
Protein
Secretion
14 Citations (Scopus)

In vitro aggregation of the regulated secretory protein chromogranin A

Jain, R. K., Chang, W. T., Geetha, C., Joyce, P. B. M. & Gorr, S. U., Dec 1 2002, In : Biochemical Journal. 368, 2, p. 605-610 6 p.

Research output: Contribution to journalArticle

Chromogranin A
Divalent Cations
Agglomeration
His-His-His-His-His-His
Calcium
4 Citations (Scopus)

N-terminal proteolytic processing of porcine chromogranin A in parathyroid tissue

Fasciotto, B. H., Cohn, D. V. & Gorr, S. U., Jan 15 2002, In : Regulatory Peptides. 103, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

Chromogranin A
Swine
Tissue
Processing
Secretory Vesicles
2 Citations (Scopus)

Sorting of an exocrine secretory protein to the regulated secretory pathway in endocrine cells

Cowley, D. J., Chu, M. & Gorr, S-U., Dec 2 2002, In : Biochemical and Biophysical Research Communications. 299, 1, p. 98-101 4 p.

Research output: Contribution to journalArticle

Endocrine Cells
Secretory Pathway
Sorting
Cells
Chromogranin A
2001
43 Citations (Scopus)

Comparative sorting of neuroendocrine secretory proteins: A search for common ground in a mosaic of sorting models and mechanisms

Gorr, S. U., Jain, R. K., Kuehn, U., Joyce, P. B. M. & Cowley, D. J., Feb 14 2001, In : Molecular and Cellular Endocrinology. 172, 1-2, p. 1-6 6 p.

Research output: Contribution to journalArticle

Staphylococcal Protein A
Sorting
Secretory Vesicles
Proteins
trans-Golgi Network
73 Citations (Scopus)

Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells

Jain, R. K., Joyce, P. B. M., Molinete, M., Halban, P. A. & Gorr, S. U., Dec 15 2001, In : Biochemical Journal. 360, 3, p. 645-649 5 p.

Research output: Contribution to journalArticle

Oligomerization
Endocrine Cells
Secretory Pathway
Green Fluorescent Proteins
Oligomers
2000
30 Citations (Scopus)

Aggregation chaperones enhance aggregation and storage of secretory proteins in endocrine cells

Jain, R. K., Joyce, P. B. M. & Gorr, S. U., Sep 1 2000, In : Journal of Biological Chemistry. 275, 35, p. 27032-27036 5 p.

Research output: Contribution to journalArticle

Endocrine Cells
His-His-His-His-His-His
Agglomeration
Cells
Secretory Vesicles
43 Citations (Scopus)

N- and C-terminal domains direct cell type-specific sorting of chromogranin A to secretory granules

Cowley, D. J., Mooret, Y. R., Darling, D. S., Joyce, P. B. M. & Gorr, S. U., Mar 17 2000, In : Journal of Biological Chemistry. 275, 11, p. 7743-7748 6 p.

Research output: Contribution to journalArticle

Chromogranins
Chromogranin A
Secretory Vesicles
Sorting
Secretory Pathway
19 Citations (Scopus)

Polarized secretion of the regulated secretory protein chromogranin A

Kühn, U., Cohn, D. V. & Gorr, S. U., Apr 13 2000, In : Biochemical and Biophysical Research Communications. 270, 2, p. 631-636 6 p.

Research output: Contribution to journalArticle

Chromogranin A
Proteins
Sorting
Alkaline Phosphatase
Tunicamycin
36 Citations (Scopus)

Trafficking of non-regulated secretory proteins in insulin secreting (INS-1) cells

Molinete, M., Lilla, V., Jain, R., Joyce, P. B. M., Gorr, S. U., Ravazzola, M. & Halban, P. A., Sep 30 2000, In : Diabetologia. 43, 9, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

Alkaline Phosphatase
Insulin
Proteins
Proinsulin
Secretory Pathway
1999
36 Citations (Scopus)

Disruption of disulfide bonds exhibits differential effects on trafficking of regulated secretory proteins

Gorr, S. U., Huang, X. F., Cowley, D. J., Kuliawat, R. & Aryan, P., Aug 5 1999, In : American Journal of Physiology - Cell Physiology. 277, 1 46-1

Research output: Contribution to journalArticle

Disulfides
Chromogranin B
Dithiothreitol
Secretory Vesicles
Proteins
17 Citations (Scopus)

Sorting of a constitutive secretory protein to the regulated secretory pathway of exocrine cells

Gorr, S. U. & Moore, Y. R., Apr 13 1999, In : Biochemical and Biophysical Research Communications. 257, 2, p. 545-548 4 p.

Research output: Contribution to journalArticle

Secretory Pathway
Sorting
Alkaline Phosphatase
Amylases
Proteins
1997
3 Citations (Scopus)

Re-probing of immunoblots after storage for more than a decade

Gorr, S. U., Aug 1 1997, In : BioTechniques. 23, 2, p. 250-254 5 p.

Research output: Contribution to journalArticle

Chromogranins
Chromogranin A
Clathrin
Computer-Assisted Image Processing
Parathyroid Hormone
1996
30 Citations (Scopus)
Secretogranin II
Chromogranin B
Chromogranins
Prolactin
Rats
1995
11 Citations (Scopus)

Aggregation and Concentration-Dependent Sorting of Exocrine-Regulated Secretory Proteins

Gorr, S. U. & Tseng, S. Y., Oct 4 1995, In : Biochemical and Biophysical Research Communications. 215, 1, p. 82-88 7 p.

Research output: Contribution to journalArticle

Amylases
Sorting
Agglomeration
Dexamethasone
Proteins
34 Citations (Scopus)

An N-terminal hydrophobic peak is the sorting signal of regulated secretory proteins

Gorr, S. U. & Darling, D. S., Mar 13 1995, In : FEBS Letters. 361, 1, p. 8-12 5 p.

Research output: Contribution to journalArticle

Sorting
Secretory Pathway
Proteins
Amino Acids
Endocrine Cells
5 Citations (Scopus)

Pancreastatin stimulates secretion from neonatal rat atrial cells

Gorr, S. U. & Pence, S. S., Feb 1995, In : Journal of Molecular and Cellular Cardiology. 27, 2, p. 767-771 5 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Chromogranin A
pancreastatin
Chondroitin Sulfate Proteoglycans
Peptides
1992
17 Citations (Scopus)

Autocrine inhibition of parathyroid cell secretion requires proteolytic processing of chromogranin A

Fasciotto, B. H., Gorr, S. U. & Cohn, D. V., Jun 1992, In : Bone and Mineral. 17, 3, p. 323-333 11 p.

Research output: Contribution to journalArticle

Chromogranin A
Immune Sera
Cells
Parathyroid Hormone
Processing