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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

Lipopolysaccharides Medicine & Life Sciences
Endotoxins Medicine & Life Sciences
Lipid A Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Toll-Like Receptor 8 Medicine & Life Sciences
Toll-Like Receptor 7 Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Amines Medicine & Life Sciences

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Projects 2015 2019

Adjuvant Discovery Program

David, S. A.

University of Kansas

8/1/159/29/19

Project: Research project

Research Output 1992 2018

Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue

Yoo, E., Salyer, A. C. D., Brush, M. J. H., Li, Y., Trautman, K. L., Shukla, N. M., De Beuckelaer, A., Lienenklaus, S., Deswarte, K., Lambrecht, B. N., De Geest, B. G. & David, S. A., Aug 15 2018, In : Bioconjugate Chemistry. 29, 8, p. 2741-2754 14 p.

Research output: Contribution to journalArticle

Hyaluronic acid
Vaccines
Lymphoid Tissue
Hyaluronic Acid
Immunization
3 Citations

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Nuhn, L., Van Hoecke, L., Deswarte, K., Schepens, B., Li, Y., Lambrecht, B. N., De Koker, S., David, S. A., Saelens, X. & De Geest, B. G., Sep 1 2018, In : Biomaterials. 178, p. 643-651 9 p.

Research output: Contribution to journalArticle

Viral Vaccines
Vaccines
Cancer Vaccines
Subunit Vaccines
Molecules
Toll-Like Receptor 6
Toll-Like Receptor 2
Immunization
Vaccines
Fibroblasts

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant

Van Herck, S., Van Hoecke, L., Louage, B., Lybaert, L., De Coen, R., Kasmi, S., Esser-Kahn, A. P., David, S. A., Nuhn, L., Schepens, B., Saelens, X. & De Geest, B. G., Mar 21 2018, In : Bioconjugate Chemistry. 29, 3, p. 748-760 13 p.

Research output: Contribution to journalArticle

Acetals
Vaccines
Toll-Like Receptors
Amphotericin B
Polymers
3 Citations

Identification of High-Potency Human TLR8 and Dual TLR7/TLR8 Agonists in Pyrimidine-2,4-diamines

Beesu, M., Salyer, A. C. D., Brush, M. J. H., Trautman, K. L., Hill, J. K. & David, S. A., Mar 9 2017, In : Journal of Medicinal Chemistry. 60, 5, p. 2084-2098 15 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 7
Diamines
Dendritic Cells
Interferon-gamma
Tumor Necrosis Factor-alpha