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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

Lipopolysaccharides Medicine & Life Sciences
Endotoxins Medicine & Life Sciences
Lipid A Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Toll-Like Receptor 8 Medicine & Life Sciences
Toll-Like Receptor 7 Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Amines Medicine & Life Sciences

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Projects 2015 2019

Adjuvant Discovery Program

David, S. A.

University of Kansas

8/1/159/29/19

Project: Research project

Research Output 1992 2018

1 Citations

Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue

Yoo, E., Salyer, A. C. D., Brush, M. J. H., Li, Y., Trautman, K. L., Shukla, N. M., De Beuckelaer, A., Lienenklaus, S., Deswarte, K., Lambrecht, B. N., De Geest, B. G. & David, S. A., Aug 15 2018, In : Bioconjugate Chemistry. 29, 8, p. 2741-2754 14 p.

Research output: Contribution to journalArticle

Hyaluronic acid
Vaccines
Lymphoid Tissue
Hyaluronic Acid
Immunization

Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates

Van Herck, S., Deswarte, K., Nuhn, L., Zhong, Z., Portela Catani, J. P., Li, Y., Sanders, N. N., Lienenklaus, S., De Koker, S., Lambrecht, B. N., David, S. A. & De Geest, B. G., Jan 1 2018, (Accepted/In press) In : Journal of the American Chemical Society.

Research output: Contribution to journalArticle

Amphiphiles
Micelles
Block copolymers
Lymph Nodes
Chemical activation
1 Citations

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Nuhn, L., De Koker, S., Van Lint, S., Zhong, Z., Catani, J. P., Combes, F., Deswarte, K., Li, Y., Lambrecht, B. N., Lienenklaus, S., Sanders, N. N., David, S. A., Tavernier, J. & De Geest, B. G., Jan 1 2018, (Accepted/In press) In : Advanced Materials. 1803397.

Research output: Contribution to journalArticle

Tumors
Chemical activation
Nanoparticles
T-cells
Medical nanotechnology
6 Citations

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Nuhn, L., Van Hoecke, L., Deswarte, K., Schepens, B., Li, Y., Lambrecht, B. N., De Koker, S., David, S. A., Saelens, X. & De Geest, B. G., Sep 1 2018, In : Biomaterials. 178, p. 643-651 9 p.

Research output: Contribution to journalArticle

Viral Vaccines
Vaccines
Cancer Vaccines
Subunit Vaccines
Molecules
Toll-Like Receptor 6
Toll-Like Receptor 2
Immunization
Vaccines
Fibroblasts