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Research Output 2007 2019

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Article
2019
6 Citations (Scopus)

Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas

Rathe, S., Popescu, F. E., Johnson, J. E., Watson, A. L., Marko, T. A., Moriarity, B. S., Ohlfest, J. R. & Largaespada, D. A., Dec 1 2019, In : Scientific reports. 9, 1, 358.

Research output: Contribution to journalArticle

Osteosarcoma
RNA Sequence Analysis
Gene Fusion
Immunotherapy
Canidae
2 Citations (Scopus)

Sleeping beauty screen identifies RREB1 and other genetic drivers in human B-cell lymphoma

Rahrmann, E. P., Wolf, N. K., Otto, G. M., Heltemes Harris, L. M., Ramsey, L. B., Shu, J., LaRue, R. S., Linden, M. A., Rathe, S., Starr, T., Farrar, M. A., Moriarity, B. S. & Largaespada, D. A., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 567-582 16 p.

Research output: Contribution to journalArticle

Beauty
Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Carrier Proteins
Follicular Lymphoma
2018
14 Citations (Scopus)
Gene Expression Profiling
Osteosarcoma
Survival
Multigene Family
Neoplasms
2017
3 Citations (Scopus)

Data Descriptor: Transcriptomic analysis of gene signatures associated with sickle pain

Paul, J. A., Aich, A., Abrahante, J. E., Wang, Y., LaRue, R. S., Rathe, S. K., Kalland, K., Mittal, A., Jha, R., Peng, F., Largaespada, D. A., Bagchi, A. & Gupta, K., May 16 2017, In : Scientific Data. 4, 170051.

Research output: Contribution to journalArticle

Pain
Descriptors
pain
Signature
Genes
2016
12 Citations (Scopus)

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma

Marko, T. A., Shamsan, G. A., Edwards, E. N., Hazelton, P. E., Rathe, S., Cornax, I., Overn, P. R., Varshney, J., Diessner, B. J., Moriarity, B. S., O'Sullivan, G., Odde, D. J. & Largaespada, D. A., Dec 14 2016, In : Scientific reports. 6, 39059.

Research output: Contribution to journalArticle

GTPase-Activating Proteins
Osteosarcoma
Neoplasm Metastasis
Cell Line
Clustered Regularly Interspaced Short Palindromic Repeats
16 Citations (Scopus)

Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML

Kurata, M., Rathe, S., Bailey, N. J., Aumann, N. K., Jones, J. M., Veldhuijzen, G. W., Moriarity, B. S. & Largaespada, D. A., Nov 3 2016, In : Scientific reports. 6, 36199.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Cytarabine
Guide RNA
Drug Resistance
Acute Myeloid Leukemia
2015
105 Citations (Scopus)

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

Moriarity, B. S., Otto, G. M., Rahrmann, E. P., Rathe, S. K., Wolf, N. K., Weg, M. T., Manlove, L. A., Larue, R. S., Temiz, N. A., Molyneux, S. D., Choi, K., Holly, K. J., Sarver, A. L., Scott, M. C., Forster, C. L., Modiano, J. F., Khanna, C., Hewitt, S. M., Khokha, R., Yang, Y. & 3 others, Gorlick, R., Dyer, M. A. & Largaespada, D. A., May 27 2015, In : Nature Genetics. 47, 6, p. 615-624 10 p.

Research output: Contribution to journalArticle

Beauty
Osteosarcoma
Neoplasm Metastasis
Genes
Oncogenes
12 Citations (Scopus)

Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues

Kempema, A. M., Widen, J. C., Hexum, J. K., Andrews, T. E., Wang, D., Rathe, S. K., Meece, F. A., Noble, K. E., Sachs, Z., Largaespada, D. A. & Harki, D. A., Jul 23 2015, In : Bioorganic and Medicinal Chemistry. 23, 15, p. 4737-4745 9 p.

Research output: Contribution to journalArticle

Stem cells
Cells
Stem Cells
Myeloid Cells
Acute Myeloid Leukemia
2014
14 Citations (Scopus)

NRAS G12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia

Sachs, Z., LaRue, R. S., Nguyen, H. T., Sachs, K., Noble, K. E., Hassan, N. A. M., Diaz-Flores, E., Rathe, S. K., Sarver, A. L., Bendall, S. C., Ha, N. A., Diers, M. D., Nolan, G. P., Shannon, K. M. & Largaespada, D. A., Nov 20 2014, In : Blood. 124, 22, p. 3274-3283 10 p.

Research output: Contribution to journalArticle

Oncogenes
Acute Myeloid Leukemia
Gene expression
Leukemia
Stem cells
19 Citations (Scopus)

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

Rathe, S. K., Moriarity, B. S., Stoltenberg, C. B., Kurata, M., Aumann, N. K., Rahrmann, E. P., Bailey, N. J., Melrose, E. G., Beckmann, D. A., Liska, C. R. & Largaespada, D. A., Aug 13 2014, In : Scientific reports. 4, 6048.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Cytarabine
Drug Resistance
Acute Myeloid Leukemia
RNA
2013
2 Citations (Scopus)

MMuFLR: Missense mutation and frameshift location reporter

Rathe, S., Johnson, J. E., Silverstein, K. A., Erdmann, J. J., Watson, A. L., Popescu, F. E., Ohlfest, J. R. & Largaespada, D. A., Sep 15 2013, In : Bioinformatics. 29, 18, p. 2353-2354 2 p.

Research output: Contribution to journalArticle

Missense Mutation
Mutation
Proteins
Frameshift Mutation
Cancer