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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 3 Similar Profiles
Carboxylic Acids Medicine & Life Sciences
Naphthyridines Medicine & Life Sciences
Indazoles Medicine & Life Sciences
hydrazine Medicine & Life Sciences
Cyclin-Dependent Kinases Medicine & Life Sciences
Male Contraceptive Agents Medicine & Life Sciences
Sertoli Cells Medicine & Life Sciences
Stereochemistry Chemical Compounds

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Research Output 1996 2019

N-Butyldeoxygalactonojirimycin Induces Reversible Infertility in Male CD Rats

Gupta, V., Hild, S. A., Jakkaraj, S. R., Carlson, E. J., Wong, H. L., Allen, C. L., Georg, G. & Tash, J. S., Dec 31 2019, In : International Journal of Molecular Sciences.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Stereochemistry
Enantiomers
X ray crystallography
X Ray Crystallography
Chromatography
7 Citations (Scopus)

Scalable syntheses of the BET bromodomain inhibitor JQ1

Syeda, S. S., Jakkaraj, S. R. & Georg, G., May 25 2015, In : Tetrahedron Letters. 56, 23, p. 3454-3457 4 p.

Research output: Contribution to journalArticle

2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide
Triazoles
Thioamides
Poisons
Benzodiazepines
33 Citations (Scopus)

Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases

Schonbrunn, E., Betzi, S., Alam, R., Martin, M. P., Becker, A., Han, H., Francis, R., Chakrasali, R., Jakkaraj, S., Kazi, A., Sebti, S. M., Cubitt, C. L., Gebhard, A. W., Hazlehurst, L. A., Tash, J. S. & Georg, G. I., May 23 2013, In : Journal of Medicinal Chemistry. 56, 10, p. 3768-3782 15 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Inhibitory Concentration 50
Retinoblastoma
Protein-Serine-Threonine Kinases
Cell Cycle
87 Citations (Scopus)

Discovery of a potential allosteric ligand binding site in CDK2

Betzi, S., Alam, R., Martin, M., Lubbers, D. J., Han, H., Jakkaraj, S. R., Georg, G. I. & Schönbrunn, E., May 20 2011, In : ACS Chemical Biology. 6, 5, p. 492-501 10 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Binding Sites
Ligands
Cyclin A
Cyclins