If you made any changes in Pure, your changes will be visible here soon.

Research Output 2002 2019

Filter
Article
2019
Circulating Neoplastic Cells
Platinum
MicroRNAs
Biomarkers
Prospective Studies
1 Citation (Scopus)

Intercellular transfer of oncogenic KRAS via tunneling nanotubes introduces intracellular mutational heterogeneity in colon cancer cells

Desir, S., Wong, P., Turbyville, T., Chen, D., Shetty, M., Clark, C., Zhai, E., Romin, Y., Manova-Todorova, K., Starr, T., Nissley, D. V., Steer, C. J., Subramanian, S. & Lou, E., Jul 1 2019, In : Cancers. 11, 7, 892.

Research output: Contribution to journalArticle

Open Access
Kirsten murine sarcoma virus
Nanotubes
Oncogenic Viruses
Parvovirus
Colonic Neoplasms
2 Citations (Scopus)

MicroRNA-Mediated Tumor-Microbiota Metabolic Interactions in Colorectal Cancer

Yuan, A. & Subramanian, S., Apr 1 2019, In : DNA and Cell Biology. 38, 4, p. 281-285 5 p.

Research output: Contribution to journalArticle

Open Access
Microbiota
MicroRNAs
Colorectal Neoplasms
Neoplasms
Tumor Microenvironment
2018
4 Citations (Scopus)

Cellular and molecular networking within the ecosystem of cancer cell communication via tunneling nanotubes

Lou, E., Zhai, E., Sarkari, A., Desir, S., Wong, P., Iizuka, Y., Yang, J., Subramanian, S., McCarthy, J., Bazzaro, M. & Steer, C. J., Oct 2 2018, In : Frontiers in Cell and Developmental Biology. 6, OCT, 95.

Research output: Contribution to journalArticle

Open Access
Nanotubes
Cell Communication
Ecosystem
Neoplasms
Interdisciplinary Studies
8 Citations (Scopus)

Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer

Desir, S., O'Hare, P., Vogel, R. I., Sperduto, W., Sarkari, A., Dickson, E. L., Wong, P., Nelson, A. C., Fong, Y., Steer, C. J., Subramanian, S. & Lou, E., Dec 1 2018, In : Scientific reports. 8, 1, 9484.

Research output: Contribution to journalArticle

Open Access
Nanotubes
Pancreatic Neoplasms
Drug Therapy
Pharmaceutical Preparations
Doxorubicin
14 Citations (Scopus)
Gene Expression Profiling
Osteosarcoma
Survival
Multigene Family
Neoplasms
2 Citations (Scopus)

OMCD: OncomiR Cancer Database

Sarver, A. L., Sarver, A. E., Yuan, A. & Subramanian, S., Dec 6 2018, In : BMC Cancer. 18, 1, 5085.

Research output: Contribution to journalArticle

Databases
MicroRNAs
Neoplasms
Atlases
Genome
2017
8 Citations (Scopus)

A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication

Thayanithy, V., O'Hare, P., Wong, P., Zhao, X., Steer, C. J., Subramanian, S. & Lou, E., Nov 13 2017, In : Cell Communication and Signaling. 15, 1, 46.

Research output: Contribution to journalArticle

Exosomes
Nanotubes
Assays
Communication
Oncolytic Viruses
16 Citations (Scopus)

Tumor location impacts immune response in mouse models of colon cancer

Zhao, X., Li, L., Starr, T. K. & Subramanian, S., Jan 1 2017, In : Oncotarget. 8, 33, p. 54775-54787 13 p.

Research output: Contribution to journalArticle

Open Access
Colonic Neoplasms
Colorectal Neoplasms
Neoplasms
Myeloid Cells
Immunosuppressive Agents
2016
70 Citations (Scopus)

Circular RNAs and their associations with breast cancer subtypes

Nair, A. A., Niu, N., Tang, X., Thompson, K. J., Wang, L., Kocher, J. P., Subramanian, S. & Kalari, K. R., Jan 1 2016, In : Oncotarget. 7, 49, p. 80967-80979 13 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Workflow
Atlases
Neoplasms
Genome
9 Citations (Scopus)

Comprehensive analysis of microRNA signature of mouse pancreatic acini: Overexpression of miR-21-3p in acute pancreatitis

Dixit, A. K., Sarver, A. E., Yuan, Z., George, J., Barlass, U., Cheema, H., Sareen, A., Banerjee, S., Dudeja, V., Dawra, R., Subramanian, S. & Saluja, A. K., Jan 1 2016, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 311, 5, p. G974-G980

Research output: Contribution to journalArticle

Ceruletide
Acinar Cells
MicroRNAs
Pancreatitis
RNA Sequence Analysis
2 Citations (Scopus)

Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior

Scott, M. C., Tomiyasu, H., Garbe, J. R., Cornax, I., Amaya, C., O'Sullivan, M. G., Subramanian, S., Bryan, B. A. & Modiano, J. F., Dec 1 2016, In : DMM Disease Models and Mechanisms. 9, 12, p. 1435-1444 10 p.

Research output: Contribution to journalArticle

Osteosarcoma
Canidae
Tumors
Heterografts
Cells
8 Citations (Scopus)

Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma

Shu, J., Li, L., Sarver, A. E., Pope, E. A., Varshney, J., Thayanithy, V., Spector, L., Largaespada, D. A., Steer, C. J. & Subramanian, S., Apr 19 2016, In : Oncotarget. 7, 16, p. 21298-21314 17 p.

Research output: Contribution to journalArticle

Open Access
Osteosarcoma
Gene Expression
Histone Code
Beauty
Imprinting (Psychology)
15 Citations (Scopus)

Integrated genomic analysis of pancreatic ductal adenocarcinomas reveals genomic rearrangement events as significant drivers of disease

Murphy, S. J., Hart, S. N., Halling, G. C., Johnson, S. H., Smadbeck, J. B., Drucker, T., Lima, J. F., Rohakhtar, F. R., Harris, F. R., Kosari, F., Subramanian, S., Petersen, G. M., Wiltshire, T. D., Kipp, B. R., Truty, M. J., McWilliams, R. R., Couch, F. J. & Vasmatzis, G., Feb 1 2016, In : Cancer Research. 76, 3, p. 749-761 13 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Disease Progression
Genes
Exome
Gene Dosage
13 Citations (Scopus)

MicroRNA mediated chemokine responses in human airway smooth muscle cells

Dileepan, M., Sarver, A. E., Rao, S. P., Panettieri, R. A., Subramanian, S. & Kannan, M. S., Mar 1 2016, In : PLoS One. 11, 3, e0150842.

Research output: Contribution to journalArticle

asthma
chemokines
MicroRNAs
microRNA
Chemokines
14 Citations (Scopus)

Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells

Yan, Y., Hanse, E. A., Stedman, K., Benson, J. M., Lowman, X. H., Subramanian, S. & Kelekar, A., Jul 1 2016, In : Cell Death and Differentiation. 23, 7, p. 1232-1242 11 p.

Research output: Contribution to journalArticle

Myeloid Cells
MicroRNAs
Phosphoric Monoester Hydrolases
Acute Myeloid Leukemia
Transcription Factors
26 Citations (Scopus)

Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

Desir, S., Dickson, E. L., Vogel, R. I., Thayanithy, V., Wong, P., Teoh, D., Geller, M. A., Steer, C. J., Subramanian, S. & Lou, E., Jan 1 2016, In : Oncotarget. 7, 28, p. 43150-43161 12 p.

Research output: Contribution to journalArticle

Nanotubes
Ovarian Neoplasms
Trinitrotoluene
Platinum
Cell Communication
2015
13 Citations (Scopus)

Aberrant retinoblastoma (RB)-E2F transcriptional regulation defines molecular phenotypes of osteosarcoma

Scott, M. C., Sarver, A. L., Tomiyasu, H., Cornax, I., Van Etten, J., Varshney, J., O'Sullivan, M. G., Subramanian, S. & Modiano, J. F., Nov 20 2015, In : Journal of Biological Chemistry. 290, 47, p. 28070-28083 14 p.

Research output: Contribution to journalArticle

Retinoblastoma
Osteosarcoma
Gene expression
Tumors
Deregulation
5 Citations (Scopus)

Identification, by systematic RNA sequencing, of novel candidate biomarkers and therapeutic targets in human soft tissue tumors

Sarver, A. E., Sarver, A. L., Thayanithy, V. & Subramanian, S., Sep 28 2015, In : Laboratory Investigation. 95, 9, p. 1077-1088 12 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Sarcoma
Biomarkers
Neoplasms
MicroRNAs
2 Citations (Scopus)

MicroRNA miR-182 cluster mediated modulation of RECK without changes in cell surface membrane type-1 matrix metalloproteinase (MT1-MMP)

Silva, M., Hernandez, M. E., Rojas, F., Li, L., Subramanian, S. & Wilson, M. J., Jan 1 2015, In : American Journal of Cancer Research. 5, 9, p. 2918-2928 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 14
Matrix Metalloproteinase 1
MicroRNAs
Cell Membrane
trichostatin A
6 Citations (Scopus)

The oncogenic response to MiR-335 is associated with cell surface expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) activity

Rojas, F., Hernandez, M. E., Silva, M., LI, LIHUA., Subramanian, S., Wilson, M. J. & Liu, P., Jul 23 2015, In : PloS one. 10, 7, e0132026.

Research output: Contribution to journalArticle

interstitial collagenase
Matrix Metalloproteinase 14
Tumors
cell movement
Cell Movement
29 Citations (Scopus)

Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Oliveira, A. R., Beyer, G., Chugh, R., Skube, S. J., Majumder, K., Banerjee, S., Sangwan, V., LI, LIHUA., Dawra, R. K., Subramanian, S., Saluja, A. K. & Dudeja, V., Jun 28 2015, In : Laboratory Investigation. 95, 6, p. 648-659 12 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Colonic Neoplasms
Transcriptional Activation
Growth
Colorectal Neoplasms
2014
21 Citations (Scopus)
Respiratory Hypersensitivity
Smooth Muscle Myocytes
Methacholine Chloride
Asthma
Cyclic ADP-Ribose
22 Citations (Scopus)
MAP Kinase Kinase 4
3' Untranslated Regions
MicroRNAs
Phosphatidylinositol 3-Kinases
Smooth Muscle Myocytes
38 Citations (Scopus)

Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma

Li, L., Sarver, A. L., Khatri, R., Hajeri, P. B., Kamenev, I., French, A. J., Thibodeau, S. N., Steer, C. J. & Subramanian, S., Dec 1 2014, In : Journal of Pathology. 234, 4, p. 488-501 14 p.

Research output: Contribution to journalArticle

Adenoma
Colon
Adenocarcinoma
Colonic Neoplasms
MicroRNAs
3 Citations (Scopus)

Small is the new big-interplay of miRNAs in cancer

Varshney, J. & Subramanian, S., Jan 1 2014, In : Current Science. 107, 5, p. 803-814 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
Small Untranslated RNA
Metabolic Networks and Pathways
Gene Expression
39 Citations (Scopus)

Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells

Thayanithy, V., Babatunde, V., Dickson, E. L., Wong, P., Oh, S., Ke, X., Barlas, A., Fujisawa, S., Romin, Y., Moreira, A. L., Downey, R. J., Steer, C. J., Subramanian, S., Manova-Todorova, K., Moore, M. A. S. & Lou, E., Apr 15 2014, In : Experimental Cell Research. 323, 1, p. 178-188 11 p.

Research output: Contribution to journalArticle

Exosomes
Nanotubes
Mesothelioma
Lipids
Neoplasms
61 Citations (Scopus)

Tumor-stromal cross talk: Direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes

Thayanithy, V., Dickson, E. L., Steer, C. J., Subramanian, S. & Lou, E., Nov 1 2014, In : Translational Research. 164, 5, p. 359-365 7 p.

Research output: Contribution to journalArticle

Nanotubes
MicroRNAs
Tumors
Neoplasms
Cells
2013
4 Citations (Scopus)

Expression of FGFR3 and FGFR4 and clinical risk factors associated with progression-free survival in synovial sarcoma

Charbonneau, B., Vogel, R. I., Manivel, J. C., Rizzardi, A., Schmechel, S. C., Ognjanovic, S., Subramanian, S., Largaespada, D. A. & Weigel, B. J., Sep 1 2013, In : Human pathology. 44, 9, p. 1918-1926 9 p.

Research output: Contribution to journalArticle

Synovial Sarcoma
Disease-Free Survival
Neoplasms
Tumor Biomarkers
Sarcoma
24 Citations (Scopus)

MicroRNA-135b and its circuitry networks as potential therapeutic targets in colon cancer

Khatri, R. & Subramanian, S., Dec 31 2013, In : Frontiers in Oncology. 3 OCT, Article 268.

Research output: Contribution to journalArticle

MicroRNAs
Colonic Neoplasms
Untranslated RNA
Oncogenes
Nucleic Acids
62 Citations (Scopus)

MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma.

Sarver, A. L., Thayanithy, V., Scott, M. C., Cleton-Jansen, A. M., Hogendoorn, P. C. W., Modiano, J. F. & Subramanian, S., Jan 1 2013, In : Unknown Journal. 8

Research output: Contribution to journalArticle

Open Access
Osteosarcoma
MicroRNAs
Canidae
Neoplasms
Down-Regulation
39 Citations (Scopus)

Minnelide reduces tumor burden in preclinical models of osteosarcoma

Banerjee, S., Thayanithy, V., Sangwan, V., Mackenzie, T. N., Saluja, A. K. & Subramanian, S., Jul 28 2013, In : Cancer Letters. 335, 2, p. 412-420 9 p.

Research output: Contribution to journalArticle

Osteosarcoma
Tumor Burden
Bone Neoplasms
Lung
Prodrugs
71 Citations (Scopus)

Triptolide induces the expression of miR-142-3p: A negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation

MacKenzie, T. N., Mujumdar, N., Banerjee, S., Sangwan, V., Sarver, A. L., Vickers, S., Subramanian, S. & Saluja, A. K., Jul 1 2013, In : Molecular Cancer Therapeutics. 12, 7, p. 1266-1275 10 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Pancreatic Neoplasms
Cell Proliferation
Adenocarcinoma
MicroRNAs
2012
43 Citations (Scopus)

A genome-wide approach to comparative oncology: High-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations

Angstadt, A. Y., Thayanithy, V., Subramanian, S., Modiano, J. F. & Breen, M., Nov 1 2012, In : Cancer Genetics. 205, 11, p. 572-587 16 p.

Research output: Contribution to journalArticle

Osteosarcoma
Oligonucleotides
Canidae
Genome
Cytogenetics
39 Citations (Scopus)

Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines

Thayanithy, V., Park, C., Sarver, A. L., Kartha, R. V., Korpela, D. M., Graef, A. J., Steer, C. J., Modiano, J. F. & Subramanian, S., Sep 5 2012, In : PloS one. 7, 9, e43720.

Research output: Contribution to journalArticle

osteosarcoma
Cell death
Osteosarcoma
MicroRNAs
microRNA
34 Citations (Scopus)

Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs

Shu, J., Xia, Z., Li, L., Liang, E. T., Slipek, N., Shen, D., Foo, J., Subramanian, S. & Steer, C. J., Jan 1 2012, In : RNA Biology. 9, 10, p. 1275-1287 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Messenger RNA
3' Untranslated Regions
Genes
Down-Regulation
63 Citations (Scopus)

Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma

LI, LIHUA., Sarver, A. L., Alamgir, S. & Subramanian, S., Apr 1 2012, In : Laboratory Investigation. 92, 4, p. 571-583 13 p.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
MicroRNAs
Down-Regulation
cdc Genes
Alveolar Rhabdomyosarcoma
54 Citations (Scopus)

MiR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells

Jude, J. A., Dileepan, M., Subramanian, S., Solway, J., Panettieri, R. A., Panettieri, R. A., Walseth, T. F. & Kannan, M. S., Sep 1 2012, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 303, 5

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
3' Untranslated Regions
RNA Stability
Transcription Factor AP-1
p38 Mitogen-Activated Protein Kinases
93 Citations (Scopus)

Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma

Thayanithy, V., Sarver, A. L., Kartha, R. V., Li, L., Angstadt, A. Y., Breen, M., Steer, C. J., Modiano, J. F. & Subramanian, S., Jan 1 2012, In : Bone. 50, 1, p. 171-181 11 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Osteosarcoma
MicroRNAs
Down-Regulation
DNA Copy Number Variations
20 Citations (Scopus)

Transcriptome analysis of garlic-induced hepatoprotection against alcoholic fatty liver

Raghu, R., Liu, C. T., Tsai, M. H., Tang, X., Kalari, K. R., Subramanian, S. & Sheen, L. Y., Nov 7 2012, In : Journal of Agricultural and Food Chemistry. 60, 44, p. 11104-11119 16 p.

Research output: Contribution to journalArticle

Alcoholic Fatty Liver
Garlic
fatty liver
Gene Expression Profiling
garlic
48 Citations (Scopus)

Tunneling nanotubes: A new paradigm for studying intercellular communication and therapeutics in cancer

Lou, E., Fujisawa, S., Barlas, A., Romin, Y., Manova-Todorova, K., Moore, M. A. S. & Subramanian, S., Jan 1 2012, In : Communicative and Integrative Biology. 5, 4, p. 399-403 5 p.

Research output: Contribution to journalArticle

nanotubes
Nanotubes
cell communication
therapeutics
neoplasms
2011
23 Citations (Scopus)

Expression of subtype-specific group 1 leiomyosarcoma markers in a wide variety of sarcomas by gene expression analysis and immunohistochemistry

Mills, A. M., Beck, A. H., Montgomery, K. D., Zhu, S. X., Espinosa, I., Lee, C. H., Subramanian, S., Fletcher, C. D., Van De Rijn, M. & West, R. B., Apr 1 2011, In : American Journal of Surgical Pathology. 35, 4, p. 583-589 7 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Sarcoma
Immunohistochemistry
Gene Expression
Myosin-Light-Chain Kinase
109 Citations (Scopus)

MiRNA expression in colon polyps provides evidence for a Multihit model of colon cancer

Oberg, A. L., French, A. J., Sarver, A. L., Subramanian, S., Morlan, B. W., Riska, S. M., Borralho, P. M., Cunningham, J. M., Boardman, L. A., Wang, L., Smyrk, T. C., Asmann, Y., Steer, C. J. & Thibodeau, S. N., Jun 15 2011, In : PLoS One. 6, 6, e20465.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Polyps
colorectal neoplasms
Colonic Neoplasms
colon
67 Citations (Scopus)

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

Scott, M. C., Sarver, A. L., Gavin, K. J., Thayanithy, V., Getzy, D. M., Newman, R. A., Cutter, G. R., Lindblad-Toh, K., Kisseberth, W. C., Hunter, L. E., Subramanian, S., Breen, M. & Modiano, J. F., Sep 1 2011, In : Bone. 49, 3, p. 356-367 12 p.

Research output: Contribution to journalArticle

Osteosarcoma
Dogs
Neoplasms
Gene Expression
Gene Expression Profiling
66 Citations (Scopus)
Heme Oxygenase-1
Hemin
MicroRNAs
Proteins
Enzyme activity
2010
76 Citations (Scopus)

Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours

Subramanian, S., Thayanithy, V., West, R. B., Lee, C. H., Beck, A. H., Zhu, S., Downs-Kelly, E., Montgomery, K., Goldblum, J. R., Hogendoorn, P. C. W., Corless, C. L., Oliveira, A. M., Dry, S. M., Nielsen, T. O., Rubin, B. P., Fletcher, J. A., Fletcher, C. D. M. & Van De Rijn, M., Jan 1 2010, In : Journal of Pathology. 220, 1, p. 58-70 13 p.

Research output: Contribution to journalArticle

Neurilemmoma
Gene Expression Profiling
Genome
Neurofibroma
MicroRNAs
41 Citations (Scopus)

Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells

Park, C. W., Zeng, Y., Zhang, X., Subramanian, S. & Steer, C. J., Jan 1 2010, In : RNA Biology. 7, 5, p. 606-614 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Colonic Neoplasms
Small Interfering RNA
Cytoplasm
Small Untranslated RNA
211 Citations (Scopus)

MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration

Sarver, A. L., LI, LIHUA. & Subramanian, S., Dec 1 2010, In : Cancer Research. 70, 23, p. 9570-9580 11 p.

Research output: Contribution to journalArticle

Early Growth Response Protein 1
MicroRNAs
Oncogenes
Cell Movement
Neoplasms