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Research Output 2002 2019

2013
37 Citations (Scopus)

Minnelide reduces tumor burden in preclinical models of osteosarcoma

Banerjee, S., Thayanithy, V., Sangwan, V., Mackenzie, T. N., Saluja, A. K. & Subramanian, S., Jul 28 2013, In : Cancer Letters. 335, 2, p. 412-420 9 p.

Research output: Contribution to journalArticle

Osteosarcoma
Tumor Burden
Bone Neoplasms
Lung
Prodrugs
14 Citations (Scopus)

Pancreatic cancer: Modulation of kras, micrornas, and intercellular communication in the setting of tumor heterogeneity

Lou, E., Subramanian, S. & Steer, C. J., Nov 1 2013, In : Pancreas. 42, 8, p. 1218-1226 9 p.

Research output: Contribution to journalReview article

MicroRNAs
Pancreatic Neoplasms
Neoplasms
Pancreatic Stellate Cells
ras Genes
66 Citations (Scopus)

Triptolide induces the expression of miR-142-3p: A negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation

MacKenzie, T. N., Mujumdar, N., Banerjee, S., Sangwan, V., Sarver, A. L., Vickers, S., Subramanian, S. & Saluja, A. K., Jul 1 2013, In : Molecular Cancer Therapeutics. 12, 7, p. 1266-1275 10 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Pancreatic Neoplasms
Cell Proliferation
Adenocarcinoma
MicroRNAs
2012
Osteosarcoma
Neoplasms
MicroRNAs
Genes
Down-Regulation
39 Citations (Scopus)

A genome-wide approach to comparative oncology: High-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations

Angstadt, A. Y., Thayanithy, V., Subramanian, S., Modiano, J. F. & Breen, M., Nov 1 2012, In : Cancer genetics. 205, 11, p. 572-587 16 p.

Research output: Contribution to journalArticle

Osteosarcoma
Oligonucleotides
Canidae
Genome
Cytogenetics
24 Citations (Scopus)

Circulating microRNAs as biomarkers: A new frontier in diagnostics

Steer, C. J. & Subramanian, S., Mar 1 2012, In : Liver Transplantation. 18, 3, p. 265-269 5 p.

Research output: Contribution to journalReview article

Graft Rejection
MicroRNAs
Liver Transplantation
Liver Diseases
Hepatocytes
39 Citations (Scopus)

Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines

Thayanithy, V., Park, C., Sarver, A. L., Kartha, R. V., Korpela, D. M., Graef, A. J., Steer, C. J., Modiano, J. F. & Subramanian, S., Sep 5 2012, In : PLoS One. 7, 9, e43720.

Research output: Contribution to journalArticle

osteosarcoma
Cell death
Osteosarcoma
MicroRNAs
microRNA
30 Citations (Scopus)

Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs

Shu, J., Xia, Z., Li, L., Liang, E. T., Slipek, N., Shen, D., Foo, J., Subramanian, S. & Steer, C. J., Jan 1 2012, In : RNA Biology. 9, 10, p. 1275-1287 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Messenger RNA
3' Untranslated Regions
Genes
Down-Regulation
60 Citations (Scopus)
Rhabdomyosarcoma
MicroRNAs
Down-Regulation
cdc Genes
Alveolar Rhabdomyosarcoma
15 Citations (Scopus)

MicroRNA-mediated gene regulations in human sarcomas

Subramanian, S. & Kartha, R., Nov 1 2012, In : Cellular and Molecular Life Sciences. 69, 21, p. 3571-3585 15 p.

Research output: Contribution to journalReview article

MicroRNAs
Sarcoma
Genes
Gene Regulatory Networks
Small Untranslated RNA
52 Citations (Scopus)

MiR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells

Jude, J. A., Dileepan, M., Subramanian, S., Solway, J., Panettieri, R. A., Panettieri, R. A., Walseth, T. F. & Kannan, M. S., Sep 1 2012, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 303, 5

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
3' Untranslated Regions
RNA Stability
Transcription Factor AP-1
p38 Mitogen-Activated Protein Kinases
87 Citations (Scopus)

Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma

Thayanithy, V., Sarver, A. L., Kartha, R. V., Li, L., Angstadt, A. Y., Breen, M., Steer, C. J., Modiano, J. F. & Subramanian, S., Jan 1 2012, In : Bone. 50, 1, p. 171-181 11 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Osteosarcoma
MicroRNAs
Down-Regulation
DNA Copy Number Variations
19 Citations (Scopus)

Transcriptome analysis of garlic-induced hepatoprotection against alcoholic fatty liver

Raghu, R., Liu, C. T., Tsai, M. H., Tang, X., Kalari, K. R., Subramanian, S. & Sheen, L. Y., Nov 7 2012, In : Journal of Agricultural and Food Chemistry. 60, 44, p. 11104-11119 16 p.

Research output: Contribution to journalArticle

Alcoholic Fatty Liver
Garlic
fatty liver
Gene Expression Profiling
garlic
46 Citations (Scopus)
nanotubes
Nanotubes
cell communication
therapeutics
neoplasms
2011
21 Citations (Scopus)

Expression of subtype-specific group 1 leiomyosarcoma markers in a wide variety of sarcomas by gene expression analysis and immunohistochemistry

Mills, A. M., Beck, A. H., Montgomery, K. D., Zhu, S. X., Espinosa, I., Lee, C. H., Subramanian, S., Fletcher, C. D., Van De Rijn, M. & West, R. B., Apr 1 2011, In : American Journal of Surgical Pathology. 35, 4, p. 583-589 7 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Sarcoma
Immunohistochemistry
Gene Expression
Myosin-Light-Chain Kinase
52 Citations (Scopus)
Liver Regeneration
MicroRNAs
Down-Regulation
Hepatectomy
Regulator Genes
106 Citations (Scopus)

MiRNA expression in colon polyps provides evidence for a Multihit model of colon cancer

Oberg, A. L., French, A. J., Sarver, A. L., Subramanian, S., Morlan, B. W., Riska, S. M., Borralho, P. M., Cunningham, J. M., Boardman, L. A., Wang, L., Smyrk, T. C., Asmann, Y., Steer, C. J. & Thibodeau, S. N., Jun 15 2011, In : PLoS One. 6, 6, e20465.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Polyps
colorectal neoplasms
Colonic Neoplasms
colon
65 Citations (Scopus)
Osteosarcoma
Dogs
Neoplasms
Gene Expression
Gene Expression Profiling
63 Citations (Scopus)
Heme Oxygenase-1
Hemin
MicroRNAs
Proteins
Enzyme activity
2010
76 Citations (Scopus)

Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours

Subramanian, S., Thayanithy, V., West, R. B., Lee, C. H., Beck, A. H., Zhu, S., Downs-Kelly, E., Montgomery, K., Goldblum, J. R., Hogendoorn, P. C. W., Corless, C. L., Oliveira, A. M., Dry, S. M., Nielsen, T. O., Rubin, B. P., Fletcher, J. A., Fletcher, C. D. M. & Van De Rijn, M., Jan 1 2010, In : Journal of Pathology. 220, 1, p. 58-70 13 p.

Research output: Contribution to journalArticle

Neurilemmoma
Gene Expression Profiling
Genome
Neurofibroma
MicroRNAs
38 Citations (Scopus)

Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells

Park, C. W., Zeng, Y., Zhang, X., Subramanian, S. & Steer, C. J., Jan 1 2010, In : RNA Biology. 7, 5, p. 606-614 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Colonic Neoplasms
Small Interfering RNA
Cytoplasm
Small Untranslated RNA
200 Citations (Scopus)

MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration

Sarver, A. L., LI, LIHUA. & Subramanian, S., Dec 1 2010, In : Cancer Research. 70, 23, p. 9570-9580 11 p.

Research output: Contribution to journalArticle

Early Growth Response Protein 1
MicroRNAs
Oncogenes
Cell Movement
Neoplasms
112 Citations (Scopus)

MicroRNAs as gatekeepers of apoptosis

Subramanian, S. & Steer, C. J., May 1 2010, In : Journal of Cellular Physiology. 223, 2, p. 289-298 10 p.

Research output: Contribution to journalShort survey

MicroRNAs
Apoptosis
Genes
Cell death
Cell Death
33 Citations (Scopus)

MicroRNAs in cardiovascular diseases: Biology and potential clinical applications

Kartha, R. & Subramanian, S., Jun 1 2010, In : Journal of cardiovascular translational research. 3, 3, p. 256-270 15 p.

Research output: Contribution to journalReview article

MicroRNAs
Cardiovascular Diseases
Heart Diseases
Small Untranslated RNA
Therapeutic Uses
70 Citations (Scopus)

S-MED: Sarcoma microRNA Expression Database

Sarver, A. L., Phalak, R., Thayanithy, V. & Subramanian, S., May 1 2010, In : Laboratory Investigation. 90, 5, p. 753-761 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Sarcoma
Databases
Neoplasms
Hemangiosarcoma
2009
111 Citations (Scopus)

A compact VEGF signature associated with distant metastases and poor outcomes

Hu, Z., Fan, C., Livasy, C., He, X., Oh, D. S., Ewend, M. G., Carey, L. A., Subramanian, S., West, R., Ikpatt, F., Olopade, O. I., van de Rijn, M. & Perou, C. M., Mar 16 2009, In : BMC Medicine. 7, 9.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Neoplasm Metastasis
Neoplasms
Breast Neoplasms
Monocarboxylic Acid Transporters
103 Citations (Scopus)

Gene networks and microRNAs implicated in aggressive prostate cancer

Wang, L., Tang, H., Thayanithy, V., Subramanian, S., Oberg, A. L., Cunningham, J. M., Cerhan, J. R., Steer, C. J. & Thibodeau, S. N., Dec 15 2009, In : Cancer Research. 69, 24, p. 9490-9497 8 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
MicroRNAs
Prostatic Neoplasms
Genes
Phenotype
61 Citations (Scopus)

Genome-wide transcriptional profiling reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines

Wang, L., Oberg, A. L., Asmann, Y. W., Sicotte, H., McDonnell, S. K., Riska, S. M., Liu, W., Steer, C. J., Subramanian, S., Cunningham, J. M., Cerhan, J. R. & Thibodeau, S. N., Jun 11 2009, In : PLoS One. 4, 6, e5878.

Research output: Contribution to journalArticle

Biological Phenomena
human cell lines
MicroRNAs
microRNA
Genes
236 Citations (Scopus)

Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

Sarver, A. L., French, A. J., Borralho, P. M., Thayanithy, V., Oberg, A. L., Silverstein, K. A., Morlan, B. W., Riska, S. M., Boardman, L. A., Cunningham, J. M., Subramanian, S., Wang, L., Smyrk, T. C., Rodrigues, C. M. P., Thibodeau, S. N. & Steer, C. J., Nov 18 2009, In : BMC Cancer. 9, 401.

Research output: Contribution to journalArticle

DNA Mismatch Repair
MicroRNAs
Colonic Neoplasms
Neoplasms
Colon
152 Citations (Scopus)

Intraepithelial T cells and prognosis in ovarian carcinoma: Novel associations with stage, tumor type, and BRCA1 loss

Clarke, B., Tinker, A. V., Lee, C. H., Subramanian, S., Van De Rijn, M., Turbin, D., Kalloger, S., Han, G., Ceballos, K., Cadungog, M. G., Huntsman, D. G., Coukos, G. & Gilks, C. B., Jan 1 2009, In : Modern Pathology. 22, 3, p. 393-402 10 p.

Research output: Contribution to journalArticle

Carcinoma
T-Lymphocytes
Neoplasms
Survival
Ovarian Neoplasms
76 Citations (Scopus)

MicroRNA profiling of BRCA1/2 mutation-carrying and non-mutation-carrying high-grade serous carcinomas of ovary

Lee, C. H., Subramanian, S., Beck, A. H., Espinosa, I., Senz, J., Zhu, S. X., Huntsman, D., van de Rijn, M. & Gilks, C. B., Oct 2 2009, In : PLoS One. 4, 10, e7314.

Research output: Contribution to journalArticle

MicroRNAs
microRNA
carcinoma
Ovary
Carcinoma
2008
295 Citations (Scopus)

A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors

Espinosa, I., Lee, C. H., Kim, M. K., Rouse, B. T., Subramanian, S., Montgomery, K., Varma, S., Corless, C. L., Heinrich, M. C., Smith, K. S., Wang, Z., Rubin, B., Nielsen, T. O., Seitz, R. S., Ross, D. T., West, R. B., Cleary, M. L. & Van De Rijn, M., Feb 1 2008, In : American Journal of Surgical Pathology. 32, 2, p. 210-218 9 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Monoclonal Antibodies
Receptor Protein-Tyrosine Kinases
Antibodies
Staining and Labeling
50 Citations (Scopus)
Giant Cell Tumor of Bone
Gene Expression Profiling
Chondroblastoma
Aneurysmal Bone Cysts
Neoplasms
79 Citations (Scopus)
Synovial Sarcoma
Histone Deacetylase Inhibitors
Growth
Neoplasms
Genes
180 Citations (Scopus)

MicroRNA expression signature of human sarcomas

Subramanian, S., Lui, W. O., Lee, C. H., Espinosa, I., Nielsen, T. O., Heinrich, M. C., Corless, C. L., Fire, A. Z. & Van De Rijn, M., Mar 27 2008, In : Oncogene. 27, 14, p. 2015-2026 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Sarcoma
Neoplasms
Organism Cloning
Skeletal Muscle
95 Citations (Scopus)

Prognostic significance of macrophage infiltration in leiomyosarcomas

Lee, C. H., Espinosa, I., Vrijaldenhoven, S., Subramanian, S., Montgomery, K. D., Zhu, S., Marinelli, R. J., Peterse, J. L., Poulin, N., Nielsen, T. O., West, R. B., Gilks, C. B. & Van De Rijn, M., Mar 1 2008, In : Clinical Cancer Research. 14, 5, p. 1423-1430 8 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Macrophages
Neoplasms
Gene Expression Profiling
Survival
2007
197 Citations (Scopus)

TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies

Terry, J., Saito, T., Subramanian, S., Ruttan, C., Antonescu, C. R., Goldblum, J. R., Downs-Kelly, E., Corless, C. L., Rubin, B. P., Van De Rijn, M., Ladanyi, M. & Nielsen, T. O., Feb 1 2007, In : American Journal of Surgical Pathology. 31, 2, p. 240-246 7 p.

Research output: Contribution to journalArticle

Synovial Sarcoma
Gene Expression Profiling
Neurilemmoma
Neoplasms
Staining and Labeling
2006
220 Citations (Scopus)

A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells

West, R. B., Rubin, B. P., Miller, M. A., Subramanian, S., Kaygusuz, G., Montgomery, K., Zhu, S., Marinelli, R. J., De Luca, A., Downs-Kelly, E., Goldblum, J. R., Corless, C. L., Brown, P. O., Gilks, C. B., Nielsen, T. O., Huntsman, D. & Van De Rijn, M., Jan 17 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 3, p. 690-695 6 p.

Research output: Contribution to journalArticle

Pigmented Villonodular Synovitis
Neoplasms
Chromosome Breakpoints
Adjustment Disorders
Genetic Translocation
2005
9 Citations (Scopus)

A mouse gene encoding a novel member of the WD family of proteins is highly conserved and predominantly expressed in the testis (Wdr13)

Suresh, A., Shah, V., Rani, D. S., Singh, B. N., Umaprasad, G., Subramanian, S., Kumar, S. & Singh, L., Nov 1 2005, In : Molecular Reproduction and Development. 72, 3, p. 299-310 12 p.

Research output: Contribution to journalArticle

Testis
Genes
Proteins
Neural Stem Cells
Recombinant DNA
165 Citations (Scopus)

Determination of stromal signatures in breast carcinoma

West, R. B., Nuyten, D. S. A., Subramanian, S., Nielsen, T. O., Corless, C. L., Rubin, B. P., Montgomery, K., Zhu, S., Patel, R., Hernandez-Boussard, T., Goldblum, J. R., Brown, P. O., Van De Vijver, M. & Van De Rijn, M., Jun 2005, In : PLoS Biology. 3, 6, p. 1101-1110 10 p., e187.

Research output: Contribution to journalArticle

breast neoplasms
Tumors
Solitary Fibrous Tumors
Breast Neoplasms
Aggressive Fibromatosis
49 Citations (Scopus)

The gene expression profile of extraskeletal myxoid chondrosarcoma

Subramanian, S., West, R. B., Marinelli, R. J., Nielsen, T. O., Rubin, B. P., Goldblum, J. R., Patel, R. M., Zhu, S., Montgomery, K., Ng, T. L., Corless, C. L., Heinrich, M. C. & van de Rijn, M., Aug 1 2005, In : Journal of Pathology. 206, 4, p. 433-444 12 p.

Research output: Contribution to journalReview article

Transcriptome
Sarcoma
Gene Expression Profiling
Neoplasms
Gene Expression
2004
21 Citations (Scopus)

Extreme conservation of noncoding DNA near HoxD complex of vertebrates

Sabarinadh, C., Subramanian, S., Tripathi, A. & Mishra, R. K., Oct 6 2004, In : BMC Genomics. 5, 75.

Research output: Contribution to journalArticle

Vertebrates
Homeobox Genes
Fishes
DNA
Reptiles
110 Citations (Scopus)

Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles

Subramanian, S., West, R. B., Corless, C. L., Ou, W., Rubin, B. P., Chu, K. M., Leung, S. Y., Yuen, S. T., Zhu, S., Hernandez-Boussard, T., Montgomery, K., Nielsen, T. O., Patel, R. M., Goldblum, J. R., Heinrich, M. C., Fletcher, J. A. & Van De Rijn, M., Oct 14 2004, In : Oncogene. 23, 47, p. 7780-7790 11 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Transcriptome
Mutation
Exons
Genes
429 Citations (Scopus)
Gastrointestinal Stromal Tumors
Mutation
Neoplasms
Aggressive Fibromatosis
Fibroma
2003
12 Citations (Scopus)

A highly conserved human gene encoding a novel member of WD-repeat family of proteins (WDR13)

Singh, B. N., Suresh, A., UmaPrasad, G., Subramanian, S., Sultana, M., Goel, S., Kumar, S. & Singh, L., Mar 1 2003, In : Genomics. 81, 3, p. 315-328 14 p.

Research output: Contribution to journalArticle

Genes
Proteins
Genetically Modified Animals
5' Untranslated Regions
Expressed Sequence Tags
38 Citations (Scopus)
Bungarus
Sex Chromosomes
Chromatin
Chromosome
Minor
211 Citations (Scopus)
Microsatellite Repeats
genomics
genome
Genome
microsatellite repeats
19 Citations (Scopus)

SSRD: Simple sequence repeats database of the human genome

Subramanian, S., Madgula, V. M., George, R., Kumar, S., Pandit, M. W. & Singh, L., Jun 1 2003, In : Comparative and Functional Genomics. 4, 3, p. 342-345 4 p.

Research output: Contribution to journalArticle

Human Genome
Microsatellite Repeats
Databases
Untranslated Regions
Intergenic DNA
19 Citations (Scopus)

Triplet repeats in human genome: Distribution and their association with genes and other genomic regions

Subramanian, S., Madgula, V. M., Mishra, R. K., Mishra, R. K., Pandit, M. W. & Singh, L., Jul 22 2003, In : Bioinformatics. 19, 11, 1 p.

Research output: Contribution to journalComment/debate

Trinucleotide Repeats
Genes
32 Citations (Scopus)
Trinucleotide Repeats
Human Genome
Genomics
Genome
Genes