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Research Output 2002 2019

2019
Circulating Neoplastic Cells
Platinum
MicroRNAs
Biomarkers
Prospective Studies
1 Citation (Scopus)

Host–microRNA–microbiota interactions in colorectal cancer

Yuan, C., Steer, C. J. & Subramanian, S., Apr 1 2019, In : Genes. 10, 4, 4027.

Research output: Contribution to journalReview article

Open Access
MicroRNAs
Colorectal Neoplasms
Tumor Microenvironment
Microbiota
Neoplasms
1 Citation (Scopus)

Intercellular transfer of oncogenic KRAS via tunneling nanotubes introduces intracellular mutational heterogeneity in colon cancer cells

Desir, S., Wong, P., Turbyville, T., Chen, D., Shetty, M., Clark, C., Zhai, E., Romin, Y., Manova-Todorova, K., Starr, T., Nissley, D. V., Steer, C. J., Subramanian, S. & Lou, E., Jul 1 2019, In : Cancers. 11, 7, 892.

Research output: Contribution to journalArticle

Open Access
Kirsten murine sarcoma virus
Nanotubes
Oncogenic Viruses
Parvovirus
Colonic Neoplasms
2 Citations (Scopus)

MicroRNA-Mediated Tumor-Microbiota Metabolic Interactions in Colorectal Cancer

Yuan, A. & Subramanian, S., Apr 1 2019, In : DNA and Cell Biology. 38, 4, p. 281-285 5 p.

Research output: Contribution to journalArticle

Open Access
Microbiota
MicroRNAs
Colorectal Neoplasms
Neoplasms
Tumor Microenvironment

Special issue: MicroRNA regulation in health and disease

Subramanian, S. & Steer, C. J., Jun 1 2019, In : Genes. 10, 6, 457.

Research output: Contribution to journalEditorial

Open Access
MicroRNAs
Health
2018
3 Citations (Scopus)

CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms

Deshpande, D. A., Guedes, A. G. P., Graeff, R., Dogan, S., Subramanian, S., Walseth, T. F. & Kannan, M. S., Jan 1 2018, In : Mediators of inflammation. 2018, 8942042.

Research output: Contribution to journalReview article

Open Access
Cyclic ADP-Ribose
Smooth Muscle
ADP-ribosyl Cyclase
Asthma
Cytokines
4 Citations (Scopus)

Cellular and molecular networking within the ecosystem of cancer cell communication via tunneling nanotubes

Lou, E., Zhai, E., Sarkari, A., Desir, S., Wong, P., Iizuka, Y., Yang, J., Subramanian, S., McCarthy, J., Bazzaro, M. & Steer, C. J., Oct 2 2018, In : Frontiers in Cell and Developmental Biology. 6, OCT, 95.

Research output: Contribution to journalArticle

Open Access
Nanotubes
Cell Communication
Ecosystem
Neoplasms
Interdisciplinary Studies
8 Citations (Scopus)

Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer

Desir, S., O'Hare, P., Vogel, R. I., Sperduto, W., Sarkari, A., Dickson, E. L., Wong, P., Nelson, A. C., Fong, Y., Steer, C. J., Subramanian, S. & Lou, E., Dec 1 2018, In : Scientific reports. 8, 1, 9484.

Research output: Contribution to journalArticle

Open Access
Nanotubes
Pancreatic Neoplasms
Drug Therapy
Pharmaceutical Preparations
Doxorubicin
14 Citations (Scopus)
Gene Expression Profiling
Osteosarcoma
Survival
Multigene Family
Neoplasms
1 Citation (Scopus)

Genotypic and phenotypic signatures to predict immune checkpoint blockade therapy response in patients with colorectal cancer

Zhao, X., May, A., Lou, E. & Subramanian, S., Jun 1 2018, In : Translational Research. 196, p. 62-70 9 p.

Research output: Contribution to journalReview article

Open Access
Microsatellite Repeats
Colorectal Neoplasms
Tumors
Microsatellite Instability
Therapeutics
7 Citations (Scopus)

Mechanisms of intrinsic tumor resistance to immunotherapy

Rieth, J. & Subramanian, S., May 2 2018, In : International journal of molecular sciences. 19, 5, 1393.

Research output: Contribution to journalReview article

Immunotherapy
Tumors
tumors
Neoplasms
cancer

Mechanisms of Intrinsic Tumor Resistance to Immunotherapy

Rieth, J. & Subramanian, S., May 2 2018, In : International journal of molecular sciences. 19, 5

Research output: Contribution to journalReview article

Immunotherapy
Tumors
tumors
Neoplasms
cancer
2 Citations (Scopus)

OMCD: OncomiR Cancer Database

Sarver, A. L., Sarver, A. E., Yuan, A. & Subramanian, S., Dec 6 2018, In : BMC Cancer. 18, 1, 5085.

Research output: Contribution to journalArticle

Databases
MicroRNAs
Neoplasms
Atlases
Genome
9 Citations (Scopus)

Oncogenic pathways that affect antitumor immune response and immune checkpoint blockade therapy

Zhao, X. & Subramanian, S., Jan 1 2018, In : Pharmacology and Therapeutics. 181, p. 76-84 9 p.

Research output: Contribution to journalReview article

Neoplasms
Therapeutics
Translational Medical Research
Immunosuppressive Agents
Allergy and Immunology
2017
8 Citations (Scopus)

A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication

Thayanithy, V., O'Hare, P., Wong, P., Zhao, X., Steer, C. J., Subramanian, S. & Lou, E., Nov 13 2017, In : Cell Communication and Signaling. 15, 1, 46.

Research output: Contribution to journalArticle

Exosomes
Nanotubes
Assays
Communication
Oncolytic Viruses
11 Citations (Scopus)

CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets

Deshpande, D. A., Guedes, A. G. P., Lund, F. E., Subramanian, S., Walseth, T. F. & Kannan, M. S., Apr 1 2017, In : Pharmacology and Therapeutics. 172, p. 116-126 11 p.

Research output: Contribution to journalReview article

Open Access
Adenosine Diphosphate Ribose
Smooth Muscle Myocytes
NADP
NAD
Smooth Muscle
10 Citations (Scopus)

Imaging Tunneling Membrane Tubes Elucidates Cell Communication in Tumors

Thayanithy, V., Desir, S., Gholami, S., Romin, Y., Fujisawa, S., Manova-Todorova, K., Steer, C. J., Subramanian, S., Fong, Y. & Moore, M. A. S., Oct 1 2017, In : Trends in Cancer. 3, 10, p. 678-685 8 p.

Research output: Contribution to journalReview article

Nanotubes
Cell Communication
Membranes
Neoplasms
Microscopy
36 Citations (Scopus)

Intrinsic resistance of solid tumors to immune checkpoint blockade therapy

Zhao, X. & Subramanian, S., Feb 15 2017, In : Cancer Research. 77, 4, p. 817-822 6 p.

Research output: Contribution to journalReview article

Neoplasms
Tumor Microenvironment
Therapeutics
Immunosuppressive Agents
Immunotherapy
4 Citations (Scopus)
Open Access
Nanotubes
Cell culture
Cell Culture Techniques
Communication
Neurodegenerative Diseases
16 Citations (Scopus)

Tumor location impacts immune response in mouse models of colon cancer

Zhao, X., Li, L., Starr, T. K. & Subramanian, S., Jan 1 2017, In : Oncotarget. 8, 33, p. 54775-54787 13 p.

Research output: Contribution to journalArticle

Open Access
Colonic Neoplasms
Colorectal Neoplasms
Neoplasms
Myeloid Cells
Immunosuppressive Agents
2016
70 Citations (Scopus)

Circular RNAs and their associations with breast cancer subtypes

Nair, A. A., Niu, N., Tang, X., Thompson, K. J., Wang, L., Kocher, J. P., Subramanian, S. & Kalari, K. R., Jan 1 2016, In : Oncotarget. 7, 49, p. 80967-80979 13 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Workflow
Atlases
Neoplasms
Genome
9 Citations (Scopus)

Comprehensive analysis of microRNA signature of mouse pancreatic acini: Overexpression of miR-21-3p in acute pancreatitis

Dixit, A. K., Sarver, A. E., Yuan, Z., George, J., Barlass, U., Cheema, H., Sareen, A., Banerjee, S., Dudeja, V., Dawra, R., Subramanian, S. & Saluja, A. K., Jan 1 2016, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 311, 5, p. G974-G980

Research output: Contribution to journalArticle

Ceruletide
Acinar Cells
MicroRNAs
Pancreatitis
RNA Sequence Analysis
2 Citations (Scopus)

Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior

Scott, M. C., Tomiyasu, H., Garbe, J. R., Cornax, I., Amaya, C., O'Sullivan, M. G., Subramanian, S., Bryan, B. A. & Modiano, J. F., Dec 1 2016, In : DMM Disease Models and Mechanisms. 9, 12, p. 1435-1444 10 p.

Research output: Contribution to journalArticle

Osteosarcoma
Canidae
Tumors
Heterografts
Cells
8 Citations (Scopus)

Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma

Shu, J., Li, L., Sarver, A. E., Pope, E. A., Varshney, J., Thayanithy, V., Spector, L., Largaespada, D. A., Steer, C. J. & Subramanian, S., Apr 19 2016, In : Oncotarget. 7, 16, p. 21298-21314 17 p.

Research output: Contribution to journalArticle

Open Access
Osteosarcoma
Gene Expression
Histone Code
Beauty
Imprinting (Psychology)
1 Citation (Scopus)

Imprinting defects in osteosarcoma: DNA- and chromatin-modifying drugs hold promise for osteosarcoma therapy

Sarver, A. E. & Subramanian, S., Jul 1 2016, In : Epigenomics. 8, 7, p. 885-888 4 p.

Research output: Contribution to journalReview article

Osteosarcoma
DNA Methylation
MicroRNAs
Epigenomics
Chromatin
15 Citations (Scopus)

Integrated genomic analysis of pancreatic ductal adenocarcinomas reveals genomic rearrangement events as significant drivers of disease

Murphy, S. J., Hart, S. N., Halling, G. C., Johnson, S. H., Smadbeck, J. B., Drucker, T., Lima, J. F., Rohakhtar, F. R., Harris, F. R., Kosari, F., Subramanian, S., Petersen, G. M., Wiltshire, T. D., Kipp, B. R., Truty, M. J., McWilliams, R. R., Couch, F. J. & Vasmatzis, G., Feb 1 2016, In : Cancer Research. 76, 3, p. 749-761 13 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Disease Progression
Genes
Exome
Gene Dosage
13 Citations (Scopus)

MicroRNA mediated chemokine responses in human airway smooth muscle cells

Dileepan, M., Sarver, A. E., Rao, S. P., Panettieri, R. A., Subramanian, S. & Kannan, M. S., Mar 1 2016, In : PLoS One. 11, 3, e0150842.

Research output: Contribution to journalArticle

asthma
chemokines
MicroRNAs
microRNA
Chemokines
14 Citations (Scopus)

Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells

Yan, Y., Hanse, E. A., Stedman, K., Benson, J. M., Lowman, X. H., Subramanian, S. & Kelekar, A., Jul 1 2016, In : Cell Death and Differentiation. 23, 7, p. 1232-1242 11 p.

Research output: Contribution to journalArticle

Myeloid Cells
MicroRNAs
Phosphoric Monoester Hydrolases
Acute Myeloid Leukemia
Transcription Factors
26 Citations (Scopus)

Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

Desir, S., Dickson, E. L., Vogel, R. I., Thayanithy, V., Wong, P., Teoh, D., Geller, M. A., Steer, C. J., Subramanian, S. & Lou, E., Jan 1 2016, In : Oncotarget. 7, 28, p. 43150-43161 12 p.

Research output: Contribution to journalArticle

Nanotubes
Ovarian Neoplasms
Trinitrotoluene
Platinum
Cell Communication
11 Citations (Scopus)

Understanding the osteosarcoma pathobiology: A comparative oncology approach

Varshney, J., Scott, M. C., Largaespada, D. A. & Subramanian, S., Mar 1 2016, In : Veterinary Sciences. 3, 1, 3.

Research output: Contribution to journalReview article

osteosarcoma
Osteosarcoma
dogs
Canidae
animal models
2015
13 Citations (Scopus)

Aberrant retinoblastoma (RB)-E2F transcriptional regulation defines molecular phenotypes of osteosarcoma

Scott, M. C., Sarver, A. L., Tomiyasu, H., Cornax, I., Van Etten, J., Varshney, J., O'Sullivan, M. G., Subramanian, S. & Modiano, J. F., Nov 20 2015, In : Journal of Biological Chemistry. 290, 47, p. 28070-28083 14 p.

Research output: Contribution to journalArticle

Retinoblastoma
Osteosarcoma
Gene expression
Tumors
Deregulation
5 Citations (Scopus)

Identification, by systematic RNA sequencing, of novel candidate biomarkers and therapeutic targets in human soft tissue tumors

Sarver, A. E., Sarver, A. L., Thayanithy, V. & Subramanian, S., Sep 28 2015, In : Laboratory Investigation. 95, 9, p. 1077-1088 12 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Sarcoma
Biomarkers
Neoplasms
MicroRNAs
2 Citations (Scopus)

MicroRNA miR-182 cluster mediated modulation of RECK without changes in cell surface membrane type-1 matrix metalloproteinase (MT1-MMP)

Silva, M., Hernandez, M. E., Rojas, F., Li, L., Subramanian, S. & Wilson, M. J., Jan 1 2015, In : American Journal of Cancer Research. 5, 9, p. 2918-2928 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 14
Matrix Metalloproteinase 1
MicroRNAs
Cell Membrane
trichostatin A
19 Citations (Scopus)

MicroRNA Regulation of Airway Inflammation and Airway Smooth Muscle Function: Relevance to Asthma

Deshpande, D. A., Dileepan, M., Walseth, T. F., Subramanian, S. & Kannan, M. S., Sep 1 2015, In : Drug Development Research. 76, 6, p. 286-295 10 p.

Research output: Contribution to journalReview article

MicroRNAs
Smooth Muscle
Asthma
Inflammation
Gene Expression
24 Citations (Scopus)

MicroRNAs as potential target in human bone and soft tissue sarcoma therapeutics

Varshney, J. & Subramanian, S., Jun 17 2015, In : Frontiers in Molecular Biosciences. 2, JUN, 31.

Research output: Contribution to journalReview article

MicroRNAs
Sarcoma
Bone
Tissue
Bone and Bones
3 Citations (Scopus)

Micrornas in the malignant transformation process

Sarver, A. E., LI, LIHUA., Kartha, R. & Subramanian, S., Jan 1 2015, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 1-21 21 p. (Advances in Experimental Medicine and Biology; vol. 889).

Research output: Chapter in Book/Report/Conference proceedingChapter

MicroRNAs
Tumors
Neoplasms
Biomarkers
Tissue

MicroRNAs in the pathobiology of sarcomas

Sarver, A. E. & Subramanian, S., Sep 28 2015, In : Laboratory Investigation. 95, 9, p. 987-994 8 p.

Research output: Contribution to journalReview article

MicroRNAs
Sarcoma
Neoplasms
Untranslated RNA
Gene Regulatory Networks
6 Citations (Scopus)

The oncogenic response to MiR-335 is associated with cell surface expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) activity

Rojas, F., Hernandez, M. E., Silva, M., LI, LIHUA., Subramanian, S., Wilson, M. J. & Liu, P., Jul 23 2015, In : PloS one. 10, 7, e0132026.

Research output: Contribution to journalArticle

interstitial collagenase
Matrix Metalloproteinase 14
Tumors
cell movement
Cell Movement
29 Citations (Scopus)

Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Oliveira, A. R., Beyer, G., Chugh, R., Skube, S. J., Majumder, K., Banerjee, S., Sangwan, V., LI, LIHUA., Dawra, R. K., Subramanian, S., Saluja, A. K. & Dudeja, V., Jun 28 2015, In : Laboratory Investigation. 95, 6, p. 648-659 12 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Colonic Neoplasms
Transcriptional Activation
Growth
Colorectal Neoplasms
2 Citations (Scopus)

Tunneling nanotubes: Intercellular conduits for direct cell-to-cell communication in cancer

Lou, E. & Subramanian, S., Jan 1 2015, Intercellular Communication In Cancer. Springer Netherlands, p. 201-225 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

nanotubes
Nanotubes
cell communication
Cell Communication
neoplasms
2014
21 Citations (Scopus)
Respiratory Hypersensitivity
Smooth Muscle Myocytes
Methacholine Chloride
Asthma
Cyclic ADP-Ribose
134 Citations (Scopus)

Competing endogenous RNAs (ceRNAs): New entrants to the intricacies of gene regulation

Kartha, R. & Subramanian, S., Jan 1 2014, In : Frontiers in Genetics. 5, JAN, Article 8.

Research output: Contribution to journalReview article

MicroRNAs
RNA
Genes
Gene Regulatory Networks
Gene Expression
22 Citations (Scopus)
MAP Kinase Kinase 4
3' Untranslated Regions
MicroRNAs
Phosphatidylinositol 3-Kinases
Smooth Muscle Myocytes

Micrornas in the pathobiology of osteosarcoma

Varshney, J. & Subramanian, S., Jul 1 2014, Osteosarcoma: Symptoms, Diagnosis and Treatment Options. Nova Science Publishers, Inc., p. 165-200 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Osteosarcoma
MicroRNAs
Therapeutics
Treatment Failure
Canidae
38 Citations (Scopus)

Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma

Li, L., Sarver, A. L., Khatri, R., Hajeri, P. B., Kamenev, I., French, A. J., Thibodeau, S. N., Steer, C. J. & Subramanian, S., Dec 1 2014, In : Journal of Pathology. 234, 4, p. 488-501 14 p.

Research output: Contribution to journalArticle

Adenoma
Colon
Adenocarcinoma
Colonic Neoplasms
MicroRNAs
3 Citations (Scopus)

Small is the new big-interplay of miRNAs in cancer

Varshney, J. & Subramanian, S., Jan 1 2014, In : Current Science. 107, 5, p. 803-814 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
Small Untranslated RNA
Metabolic Networks and Pathways
Gene Expression
39 Citations (Scopus)

Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells

Thayanithy, V., Babatunde, V., Dickson, E. L., Wong, P., Oh, S., Ke, X., Barlas, A., Fujisawa, S., Romin, Y., Moreira, A. L., Downey, R. J., Steer, C. J., Subramanian, S., Manova-Todorova, K., Moore, M. A. S. & Lou, E., Apr 15 2014, In : Experimental Cell Research. 323, 1, p. 178-188 11 p.

Research output: Contribution to journalArticle

Exosomes
Nanotubes
Mesothelioma
Lipids
Neoplasms
61 Citations (Scopus)

Tumor-stromal cross talk: Direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes

Thayanithy, V., Dickson, E. L., Steer, C. J., Subramanian, S. & Lou, E., Nov 1 2014, In : Translational Research. 164, 5, p. 359-365 7 p.

Research output: Contribution to journalArticle

Nanotubes
MicroRNAs
Tumors
Neoplasms
Cells