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Research Output

2020

PBMC gene expression profiles of female Bangladeshi adults chronically exposed to arsenic-contaminated drinking water

Chen, Q. Y., Shen, S., Sun, H., Wu, F., Kluz, T., Kibriya, M. G., Chen, Y., Ahsan, H. & Costa, M., Apr 2020, In : Environmental Pollution. 259, 113672.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access
2019

The impact of TCR signal strength on resident memory T cell formation during influenza virus infection

Fiege, J. K., Stone, I. A., Fay, E. J., Markman, M. W., Wijeyesinghe, S., Macchietto, M., Shen, S., Masopust, D. & Langlois, R. A., Aug 15 2019, In : Journal of Immunology. 203, 4, p. 936-945 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo

Sjaastad, L. E., Fay, E. J., Fiege, J. K., Macchietto, M. G., Stone, I. A., Markman, M. W., Shen, S. & Langlois, R. A., Sep 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 38, p. 9610-9615 6 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells

Beura, L. K., Wijeyesinghe, S., Thompson, E. A., Macchietto, M. G., Rosato, P. C., Pierson, M. J., Schenkel, J. M., Mitchell, J. S., Vezys, V., Fife, B. T., Shen, S. & Masopust, D., Feb 20 2018, In : Immunity. 48, 2, p. 327-338.e5

Research output: Contribution to journalArticle

Open Access
49 Scopus citations
2016

Corrigendum to "Malignant human cell transformation of Marcellus shale gas drilling flow back water" [Toxicol. Appl. Pharmacol. (288/1) (2015) 121-130], DOI: 10.1016/j.taap.2015.07.011

Yao, Y., Chen, T., Shen, S. S., Niu, Y., DesMarais, T. L., Linn, R., Saunders, E., Fan, Z., Lioy, P., Kluz, T., Chen, L. C., Wu, Z. & Costa, M., Apr 1 2016, In : Toxicology and Applied Pharmacology. 296, 1 p.

Research output: Contribution to journalComment/debate

Frontal cortex transcriptome analysis of mice exposed to electronic cigarettes during early life stages

Lauterstein, D. E., Tijerina, P. B., Corbett, K., Oksuz, B. A., Shen, S. S., Gordon, T., Klein, C. B. & Zelikoff, J. T., Apr 12 2016, In : International journal of environmental research and public health. 13, 4, 417.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Molecular mechanisms of malignant transformation by low dose cadmium in normal human bronchial epithelial cells

Cartularo, L., Kluz, T., Cohen, L., Shen, S. S. & Costa, M., May 2016, In : PloS one. 11, 5, e0155002.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation

Yang, Y., Li, W., Hoque, M., Hou, L., Shen, S., Tian, B. & Dynlacht, B. D., Jan 1 2016, In : PLoS genetics. 12, 1, e1005794.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

SATB2 expression increased anchorage-independent growth and cell migration in human bronchial epithelial cells

Wu, F., Jordan, A., Kluz, T., Shen, S., Sun, H., Cartularo, L. A. & Costa, M., Feb 15 2016, In : Toxicology and Applied Pharmacology. 293, p. 30-36 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Aging and contribution of MyD88 and TRIF to expression of TLR pathway-associated genes following stimulation with Porphyromonas gingivalis

Shaik-Dasthagirisaheb, Y. B., Huang, N., Weinberg, E. O., Shen, S. S., Genco, C. A. & Gibson, F. C., Feb 1 2015, In : Journal of Periodontal Research. 50, 1, p. 89-102 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells

Wilson, A. A., Ying, L., Liesa, M., Segeritz, C. P., Mills, J. A., Shen, S. S., Jean, J., Lonza, G. C., Liberti, D. C., Lang, A. H., Nazaire, J., Gower, A. C., Müeller, F. J., Mehta, P., Ordóñez, A., Lomas, D. A., Vallier, L., Murphy, G. J., Mostoslavsky, G., Spira, A. & 4 others, Shirihai, O. S., Ramirez, M. I., Gadue, P. & Kotton, D. N., May 12 2015, In : Stem Cell Reports. 4, 5, p. 873-885 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

Erratum: TET1 is a tumor suppressor of hematopoietic malignancy

Cimmino, L., Dawlaty, M. M., Ndiaye-Lobry, D., Yap, Y. S., Bakogianni, S., Yu, Y., Bhattacharyya, S., Shaknovich, R., Geng, H., Lobry, C., Mullenders, J., King, B., Trimarchi, T., Aranda-Orgilles, B., Liu, C., Shen, S., Verma, A. K., Jaenisch, R. & Aifantis, I., Jul 21 2015, In : Nature immunology. 16, 8, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Inhibition of ß-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells

Chatterjee, S. S., Saj, A., Gocha, T., Murphy, M., Gonsalves, F. C., Zhang, X., Hayward, P., Oksuz, B. A., Shen, S. S., Madar, A., Arias, A. M. & DasGupta, R., Oct 12 2015, In : Journal of Cell Biology. 211, 1, p. 39-51 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Isolation and characterization of embryonic stem cell-derived cardiac purkinje cells

Maass, K., Shekhar, A., Lu, J., Kang, G., See, F., Kim, E. E., Delgado, C., Shen, S., Cohen, L. & Fishman, G. I., Apr 1 2015, In : STEM CELLS. 33, 4, p. 1102-1112 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Malignant human cell transformation of Marcellus Shale gas drilling flow back water

Yao, Y., Chen, T., Shen, S. S., Niu, Y., DesMarais, T. L., Linn, R., Saunders, E., Fan, Z., Lioy, P., Kluz, T., Chen, L. C., Wu, Z. & Costa, M., Oct 1 2015, In : Toxicology and Applied Pharmacology. 288, 1, p. 121-130 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

TET1 is a tumor suppressor of hematopoietic malignancy

Cimmino, L., Dawlaty, M. M., Ndiaye-Lobry, D., Yap, Y. S., Bakogianni, S., Yu, Y., Bhattacharyya, S., Shaknovich, R., Geng, H., Lobry, C., Mullenders, J., King, B., Trimarchi, T., Aranda-Orgilles, B., Liu, C., Shen, S., Verma, A. K., Jaenisch, R. & Aifantis, I., May 19 2015, In : Nature immunology. 16, 6, p. 653-662 10 p.

Research output: Contribution to journalArticle

95 Scopus citations

Tungsten-induced carcinogenesis in human bronchial epithelial cells

Laulicht, F., Brocato, J., Cartularo, L., Vaughan, J., Wu, F., Kluz, T., Sun, H., Oksuz, B. A., Shen, S., Paena, M., Medici, S., Zoroddu, M. A. & Costa, M., Oct 1 2015, In : Toxicology and Applied Pharmacology. 288, 1, p. 33-39 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Uncovering potential 'herbal probiotics' in Juzen-taiho-to through the study of associated bacterial populations

Montenegro, D., Kalpana, K., Chrissian, C., Sharma, A., Takaoka, A., Iacovidou, M., Soll, C. E., Aminova, O., Heguy, A., Cohen, L., Shen, S. & Kawamura, A., Feb 1 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 3, p. 466-469 4 p.

Research output: Contribution to journalArticle

14 Scopus citations
2014

A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers

Cheng, J., Blum, R., Bowman, C., Hu, D., Shilatifard, A., Shen, S. & Dynlacht, B. D., Mar 20 2014, In : Molecular Cell. 53, 6, p. 979-992 14 p.

Research output: Contribution to journalArticle

98 Scopus citations

Erk1/2 activity promotes chromatin features and RNAPII phosphorylation at developmental promoters in mouse ESCs

Tee, W. W., Shen, S. S., Oksuz, O., Narendra, V. & Reinberg, D., Feb 13 2014, In : Cell. 156, 4, p. 678-690 13 p.

Research output: Contribution to journalArticle

83 Scopus citations

Nascent RNA interaction keeps PRC2 activity poised and in check

Kaneko, S., Son, J., Bonasio, R., Shen, S. S. & Reinberg, D., Sep 15 2014, In : Genes and Development. 28, 18, p. 1983-1988 6 p.

Research output: Contribution to journalArticle

89 Scopus citations
2013

Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines

Mills, J. A., Wang, K., Paluru, P., Ying, L., Lu, L., Galvão, A. M., Xu, D., Yao, Y., Sullivan, S. K., Sullivan, L. M., Mac, H., Omari, A., Jean, J. C., Shen, S., Gower, A., Spira, A., Mostoslavsky, G., Kotton, D. N., French, D. L., Weiss, M. J. & 1 others, Gadue, P., Jan 1 2013, In : Blood. 122, 12, p. 2047-2051 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin

Son, J., Shen, S. S., Margueron, R. & Reinberg, D., Dec 15 2013, In : Genes and Development. 27, 24, p. 2663-2677 15 p.

Research output: Contribution to journalArticle

84 Scopus citations

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

Kaneko, S., Son, J., Shen, S. S., Reinberg, D. & Bonasio, R., Nov 1 2013, In : Nature Structural and Molecular Biology. 20, 11, p. 1258-1264 7 p.

Research output: Contribution to journalArticle

163 Scopus citations

XThe ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability

King, B., Trimarchi, T., Reavie, L., Xu, L., Mullenders, J., Ntziachristos, P., Aranda-Orgilles, B., Perez-Garcia, A., Shi, J., Vakoc, C., Sandy, P., Shen, S. S., Ferrando, A. & Aifantis, I., Jun 20 2013, In : Cell. 153, 7, 1 p.

Research output: Contribution to journalArticle

172 Scopus citations
2012

Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells

Longmire, T. A., Ikonomou, L., Hawkins, F., Christodoulou, C., Cao, Y., Jean, J. C., Kwok, L. W., Mou, H., Rajagopal, J., Shen, S. S., Dowton, A. A., Serra, M., Weiss, D. J., Green, M. D., Snoeck, H. W., Ramirez, M. I. & Kotton, D. N., Apr 6 2012, In : Cell Stem Cell. 10, 4, p. 398-411 14 p.

Research output: Contribution to journalArticle

219 Scopus citations

Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors

Tagne, J. B., Gupta, S., Gower, A. C., Shen, S. S., Varma, S., Lakshminarayanan, M., Cao, Y., Spira, A., Volkert, T. L. & Ramirez, M. I., Jan 5 2012, In : PloS one. 7, 1, e29907.

Research output: Contribution to journalArticle

26 Scopus citations

Genome-wide and caste-specific DNA methylomes of the ants camponotus floridanus and harpegnathos saltator

Bonasio, R., Li, Q., Lian, J., Mutti, N. S., Jin, L., Zhao, H., Zhang, P., Wen, P., Xiang, H., Ding, Y., Jin, Z., Shen, S. S., Wang, Z., Wang, W., Wang, J., Berger, S. L., Liebig, J., Zhang, G. & Reinberg, D., Oct 9 2012, In : Current Biology. 22, 19, p. 1755-1764 10 p.

Research output: Contribution to journalArticle

192 Scopus citations

PR-set7 and H4K20me1: At the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription

Beck, D. B., Oda, H., Shen, S. S. & Reinberg, D., Feb 15 2012, In : Genes and Development. 26, 4, p. 325-337 13 p.

Research output: Contribution to journalArticle

156 Scopus citations

Residual Expression of Reprogramming Factors Affects the Transcriptional Program and Epigenetic Signatures of Induced Pluripotent Stem Cells

Sommer, C. A., Christodoulou, C., Gianotti-Sommer, A., Shen, S. S., Sailaja, B. S., Hezroni, H., Spira, A., Meshorer, E., Kotton, D. N. & Mostoslavsky, G., Dec 14 2012, In : PloS one. 7, 12, e51711.

Research output: Contribution to journalArticle

28 Scopus citations

Self-renewing endodermal progenitor lines generated from human pluripotent stem cells

Cheng, X., Ying, L., Lu, L., Galvão, A. M., Mills, J. A., Lin, H. C., Kotton, D. N., Shen, S. S., Nostro, M. C., Choi, J. K., Weiss, M. J., French, D. L. & Gadue, P., Apr 6 2012, In : Cell Stem Cell. 10, 4, p. 371-384 14 p.

Research output: Contribution to journalArticle

141 Scopus citations
2011

Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes

Christodoulou, C., Longmire, T. A., Shen, S. S., Bourdon, A., Sommer, C. A., Gadue, P., Spira, A., Gouon-Evans, V., Murphy, G. J., Mostoslavsky, G. & Kotton, D. N., Jun 1 2011, In : Journal of Clinical Investigation. 121, 6, p. 2313-2325 13 p.

Research output: Contribution to journalArticle

38 Scopus citations
2010

Transcriptional changes associated with recovery from heart failure in the SHR

Brooks, W. W., Shen, S., Conrad, C. H., Goldstein, R. H., Deng, L. L. & Bing, O. H. L., Sep 1 2010, In : Journal of Molecular and Cellular Cardiology. 49, 3, p. 390-401 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Transition from compensated hypertrophy to systolic heart failure in the spontaneously hypertensive rat: Structure, function, and transcript analysis

Brooks, W. W., Shen, S. S., Conrad, C. H., Goldstein, R. H. & Bing, O. H. L., Feb 1 2010, In : Genomics. 95, 2, p. 84-92 9 p.

Research output: Contribution to journalArticle

26 Scopus citations