Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 6 Clean Water and Sanitation
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Collaborations and top research areas from the last five years
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Elucidating properties of T cell receptors that govern pancreatic cancer immunotherapy response
Shen, S. (PI) & Stromnes, I. M. (PI)
8/1/26 → 7/31/31
Project: Research project
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CD4 T cell dysfunction and reprogramming during sepsis
Griffith, T. S. (PI), Dileepan, T. (CoI), Gould, R. W. (CoI), Shen, S. (CoI), Kim, C. (Graduate Student), Kucaba, T. A. (Other Role) & Nelson, C. R. (Other Role)
NIH NIGMS NATL INST OF GENERAL
8/1/26 → 3/31/31
Project: Research project
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University of Minnesota Clinical and Translational Science Institute (UMN CTSI)
Aliferis, MD, PhD, C. (PI), Allen, M. L. (PI), Blazar, B. R. (PI), Crawford, P. (PI), Fair, D. A. (PI), Griffin, L. (PI), Ingbar, D. H. (PI), Saarunya, G. (PI), Wagner, J. E. (PI), Weisdorf, D. J. (PI), Beebe, T. J. (CoI), Bellin, M. D. (CoI), Berge, J. M. (CoI), Billings, J. L. (CoI), Bischof, J. C. (CoI), Brearley, A. M. (CoI), Call, K. T. (CoI), Fu, S. S. (CoI), Fulkerson, J. (CoI), Guan, W. (CoI), Hardeman, R. R. (CoI), Haynes, D. A. (CoI), Henning-Smith, C. E. (CoI), Johnson, S. (CoI), Jones-Webb, R. J. (CoI), Kozhimannil, K. B. (CoI), Langworthy, B. (CoI), Lim, H. H. (CoI), Melton-Meaux, G. B. (CoI), Nunez, A. (CoI), Pakhomov, S. V. (CoI), Pieczkiewicz, D. S. (CoI), Randolph, A. C. (CoI), Riggs, S. (CoI), Rudser, K. (CoI), Schleiss, M. R. (CoI), Shen, S. (CoI), Vaughn, B. P. (CoI) & Vock, D. M. (CoI)
NIH NATL CTR FOR ADVANCING TRAN SCIENCE
9/18/23 → 7/31/30
Project: Research project
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Harnessing activated CD4 T cells to define new mechanisms of protection in tuberculosis
Bold, T. D. (PI) & Shen, S. (PI)
NIH NATIONAL INST OF ALLERGY & INFECT DI
7/1/23 → 6/30/28
Project: Research project
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Enhancing engineered T cell therapeutic efficacy for the treatment of pancreatic ductal adenocarcinoma
Shen, S. (PI), Stromnes, I. M. (PI), Revelo, X. (CoI) & Webber, B. R. (CoI)
9/16/21 → 7/31/27
Project: Research project
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Case of complete response to immunotherapy in MMR-deficient prostate cancer associated with NK-like and CD4+CD8+ T cells
Tsai, A. K., Lozada, J. R., Kennedy, P. R., Moline, D., Pandey, R., Lyons, R. C., Luo, C., Wang, R., Arafa, A. T., Femino, E. L., Zipkowitz, S., Figueroa, A., McCann, P. J., Dallos, M. C., Elliott, A., Murugan, P., Felices, M., Zorko, N. A., Konety, B. R. & Dehm, S. M. & 7 others, , Jul 21 2026, In: Cell Reports Medicine. 7, 7, 102889.Research output: Contribution to journal › Article › peer-review
Open Access -
Select Small Non-Coding RNAs Are Determinants of Survival in Older Adults
Kraus, V. B., Ma, S., Naz, S. I., Zhang, X., Vann, C. G., Orenduff, M. C., Kraus, W. E., Shen, S., Huebner, J. L., Chou, C. H., Kummerfeld, E., Cohen, H. J. & Aliferis, C. F., Mar 2026, In: Aging cell. 25, 3, e70403.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Treg cells promote immunotherapy-induced immune evasion by restraining CD4 T cell control of MHC-I–deficient metastatic pancreatic cancer
Schmiechen, Z. C., Cruz-Hinojoza, E., Hilk, A. L., Ellefson, M. A., Tsai, A. K., Dres, O. M., Kang, L. I., Geuenich, M. J., Butler, J. Z., Burrack, A. L., Larsen, B. M., Hickok, G. H., Miller, E. A., Lonetree, C. L., Gaire, A., Pandey, R., Nanda, H. A., Chaudhury, I., Corbiere, T. & Dileepan, T. & 4 others, , Jun 2026, In: Science Immunology. 11, 120, eadz4302.Research output: Contribution to journal › Article › peer-review
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IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8+ T cells Infiltrating Pancreatic Ductal Adenocarcinoma
Schmiechen, Z. C., Nanda, H. A., Burrack, A. L., Hickok, G. H., Butler, J. Z., Cruz-Hinojoza, E., Maurice, N. J., Geuenich, M. J., Yu, C., Tsai, A. K., Lonetree, C. L., Ellefson, M. A., Hilk, A. L., Larsen, B. M., Miller, E. A., Rizzo, A. B., Campbell, K. R., Shen, S. S. & Stromnes, I. M., Jun 1 2025, In: Cancer Immunology Research. 13, 6, p. 847-866 20 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Scopus citations -
NUPR1 packaged in extracellular vesicles promotes murine triple-negative breast cancer in a type 1 interferon-independent manner
Ortiz, A., Stavrou, A., Liu, S., Chen, D., Shen, S. S. & Jin, C., 2024, In: Extracellular Vesicles and Circulating Nucleic Acids. 5, 1, p. 19-36 18 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Scopus citations