Steven G Friedenberg

Accepting PhD Students

1994 …2023
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Research Output 1994 2019

2019
3 Citations (Scopus)

A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death

Meurs, K. M., Friedenberg, S. G., Kolb, J., Saripalli, C., Tonino, P., Woodruff, K., Olby, N. J., Keene, B. W., Adin, D. B., Yost, O. L., DeFrancesco, T. C., Lahmers, S., Tou, S., Shelton, G. D. & Granzier, H., May 1 2019, In : Human Genetics. 138, 5, p. 515-524 10 p.

Research output: Contribution to journalArticle

Connectin
Sudden Cardiac Death
Dogs
Dilated Cardiomyopathy
Genetic Heterogeneity
1 Citation (Scopus)

A QIL1 variant associated with ventricular arrhythmias and sudden cardiac death in the juvenile rhodesian ridgeback dog

Meurs, K. M., Friedenberg, S. G., Olby, N. J., Condit, J., Weidman, J., Rosenthal, S. & Shelton, G. D., Feb 1 2019, In : Genes. 10, 2, 168.

Research output: Contribution to journalArticle

Open Access
Sudden Cardiac Death
Cardiac Arrhythmias
Dogs
Cardiomyopathies
Animal Models

DLA class II haplotypes show sex-specific associations with primary hypoadrenocorticism in Standard Poodle dogs

Treeful, A. E., Rendahl, A. K. & Friedenberg, S. G., May 1 2019, In : Immunogenetics. 71, 5-6, p. 373-382 10 p.

Research output: Contribution to journalArticle

Addison Disease
Haplotypes
Dogs
Population
MHC Class II Genes

Genome-wide association analysis in West Highland White Terriers with atopic dermatitis

Agler, C. S., Friedenberg, S. G., Olivry, T., Meurs, K. M. & Olby, N. J., Mar 1 2019, In : Veterinary Immunology and Immunopathology. 209, p. 1-6 6 p.

Research output: Contribution to journalArticle

atopic dermatitis
terriers
Genome-Wide Association Study
Atopic Dermatitis
highlands
1 Citation (Scopus)

The R9H phospholamban mutation is associated with highly penetrant dilated cardiomyopathy and sudden death in a spontaneous canine model

Yost, O., Friedenberg, S. G., Jesty, S. A., Olby, N. J. & Meurs, K. M., May 20 2019, In : Gene. 697, p. 118-122 5 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Sudden Death
Canidae
Mutation
Penetrance
2018
2 Citations (Scopus)

A de novo mutation in the EXT2 gene associated with osteochondromatosis in a litter of American Staffordshire Terriers

Friedenberg, S. G., Vansteenkiste, D., Yost, O., Treeful, A. E., Meurs, K. M., Tokarz, D. A. & Olby, N. J., May 1 2018, In : Journal of veterinary internal medicine. 32, 3, p. 986-992 7 p.

Research output: Contribution to journalArticle

Osteochondromatosis
litters (young animals)
mutation
Mutation
Genes
2 Citations (Scopus)

Deafness and vestibular dysfunction in a Doberman Pinscher puppy associated with a mutation in the PTPRQ gene

Guevar, J., Olby, N. J., Meurs, K. M., Yost, O. & Friedenberg, S. G., Mar 1 2018, In : Journal of veterinary internal medicine. 32, 2, p. 665-669 5 p.

Research output: Contribution to journalArticle

vif Genes
Doberman Pinscher
deafness
protein-tyrosine-phosphatase
Protein Tyrosine Phosphatases
1 Citation (Scopus)

Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration

Meurs, K. M., Friedenberg, S. G., Williams, B., Keene, B. W., Atkins, C. E., Adin, D., Aona, B., DeFrancesco, T., Tou, S. & Mackay, T., Feb 1 2018, In : Veterinary Journal. 232, p. 16-19 4 p.

Research output: Contribution to journalArticle

Dog Diseases
Mitral Valve
Dachshund
dogs
Genes
2 Citations (Scopus)

Lymphocyte Subsets in the Adrenal Glands of Dogs With Primary Hypoadrenocorticism

Friedenberg, S. G., Brown, D. L., Meurs, K. M. & Law, J. M. H., Jan 1 2018, In : Veterinary pathology. 55, 1, p. 177-181 5 p.

Research output: Contribution to journalArticle

hypoadrenocorticism
adrenal glands
Lymphocyte Subsets
Adrenal Glands
lymphocytes
2017
2 Citations (Scopus)

Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing

Friedenberg, S. G., Lunn, K. F. & Meurs, K. M., Feb 1 2017, In : Mammalian Genome. 28, 1-2, p. 56-65 10 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Genome
Dogs
Addison Disease
Mineralocorticoids
1 Citation (Scopus)

Successful surgical correction of a mesenteric volvulus with concurrent foreign body obstruction in two puppies

Jones, S., Friedenberg, S. G., Callard, J., Abernathy, L. & Guillaumin, J., Nov 1 2017, In : Journal of the American Animal Hospital Association. 53, 6, p. 297-303 7 p.

Research output: Contribution to journalArticle

volvulus
Intestinal Volvulus
foreign bodies
intestinal obstruction
puppies
2 Citations (Scopus)

Use of a vascular closure device during percutaneous arterial access in a dog with impaired hemostasis

Scansen, B. A., Hokanson, C. M., Friedenberg, S. G. & Khabiri, H., Jul 1 2017, In : Journal of Veterinary Emergency and Critical Care. 27, 4, p. 465-471 7 p.

Research output: Contribution to journalArticle

hemostasis
Hemostasis
blood vessels
thighs
Thigh
2016
2 Citations (Scopus)

Effect of disrupted mitochondria as a source of damage-associated molecular patterns on the production of tumor necrosis factor α by splenocytes from dogs

Friedenberg, S. G., Strange, H. R., Guillaumin, J., VanGundy, Z. C., Crouser, E. D. & Papenfuss, T. L., Jun 1 2016, In : American journal of veterinary research. 77, 6, p. 604-612 9 p.

Research output: Contribution to journalArticle

tumor necrosis factors
splenocytes
Canidae
Mitochondria
mitochondria
5 Citations (Scopus)

Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs

Friedenberg, S. G., Buhrman, G., Chdid, L., Olby, N. J., Olivry, T., Guillaumin, J., O’Toole, T., Goggs, R., Kennedy, L. J., Rose, R. B. & Meurs, K. M., Mar 1 2016, In : Immunogenetics. 68, 3, p. 205-217 13 p.

Research output: Contribution to journalArticle

Immune System Diseases
Alleles
Dogs
Atopic Dermatitis
Genes
3 Citations (Scopus)

Evaluation of artificial selection in Standard Poodles using whole-genome sequencing

Friedenberg, S. G., Meurs, K. M. & Mackay, T. F. C., Dec 1 2016, In : Mammalian Genome. 27, 11-12, p. 599-609 11 p.

Research output: Contribution to journalArticle

Genome
Dogs
Smell
Ubiquitination
Skull
15 Citations (Scopus)

Genotype imputation in the domestic dog

Friedenberg, S. G. & Meurs, K. M., Oct 1 2016, In : Mammalian Genome. 27, 9-10, p. 485-494 10 p.

Research output: Contribution to journalArticle

Genotype
Dogs
Single Nucleotide Polymorphism
Cluster Analysis
Software

Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy

Friedenberg, S. G., Chdid, L., Keene, B., Sherry, B., Motsinger-Reif, A. & Meurs, K. M., Jul 1 2016, In : American journal of veterinary research. 77, 7, p. 693-699 7 p.

Research output: Contribution to journalArticle

cardiomyopathy
Dilated Cardiomyopathy
Dogs
RNA
dogs
3 Citations (Scopus)

Ventricular arrhythmias in Rhodesian Ridgebacks with a family history of sudden death and results of a pedigree analysis for potential inheritance patterns

Meurs, K. M., Weidman, J. A., Rosenthal, S. L., Lahmers, K. K. & Friedenberg, S. G., May 15 2016, In : Journal of the American Veterinary Medical Association. 248, 10, p. 1135-1138 4 p.

Research output: Contribution to journalArticle

Inheritance Patterns
arrhythmia
Pedigree
Sudden Death
pedigree
2015
9 Citations (Scopus)

Splenic vasculitis, thrombosis, and infarction in a febrile dog infected with Bartonella henselae

Friedenberg, S. G., Balakrishnan, N., Guillaumin, J., Cooper, E. S., Lewis, K., Russell, D. S. & Breitschwerdt, E. B., Jan 1 2015, In : Journal of Veterinary Emergency and Critical Care. 25, 6, p. 789-794 6 p.

Research output: Contribution to journalArticle

Bartonella henselae
vasculitis
infarction
thrombosis
Vasculitis
2013
1 Citation (Scopus)

Successful treatment of a dog with massive 5-fluorouracil toxicosis

Friedenberg, S. G., Brooks, A. C., Monnig, A. A. & Cooper, E. S., Nov 1 2013, In : Journal of Veterinary Emergency and Critical Care. 23, 6, p. 643-647 5 p.

Research output: Contribution to journalArticle

fluorouracil
etiracetam
Fluorouracil
poisoning
seizures
2012
21 Citations (Scopus)

Seizures following head trauma in dogs: 259 cases (1999-2009)

Friedenberg, S. G., Butler, A. L., Wei, L., Moore, S. A. & Cooper, E. S., Dec 1 2012, In : Journal of the American Veterinary Medical Association. 241, 11, p. 1479-1483 5 p.

Research output: Contribution to journalArticle

seizures
Craniocerebral Trauma
Seizures
Dogs
dogs
3 Citations (Scopus)

The S-Measurement in the Diagnosis of Canine Hip Dysplasia

Ogden, D. M., Scrivani, P. V., Dykes, N., Lust, G., Friedenberg, S. G. & Todhunter, R. J., Jan 1 2012, In : Veterinary Surgery. 41, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

Canine Hip Dysplasia
canine hip dysplasia
hips
Hip
Dogs
2011
19 Citations (Scopus)

Canine hip dysplasia is predictable by genotyping

Guo, G., Zhou, Z., Wang, Y., Zhao, K., Zhu, L., Lust, G., Hunter, L., Friedenberg, S., Li, J., Zhang, Y., Harris, S., Jones, P., Sandler, J., Krotscheck, U., Todhunter, R. & Zhang, Z., Apr 1 2011, In : Osteoarthritis and Cartilage. 19, 4, p. 420-429 10 p.

Research output: Contribution to journalArticle

Canine Hip Dysplasia
Risk management
Breeding
Genes
Dogs
25 Citations (Scopus)

Evaluation of a fbrillin 2 gene haplotype associated with hip dysplasia and incipient osteoarthritis in dogs

Friedenberg, S. G., Zhu, L., Zhang, Z., van den Foels, W. B., Schweitzer, P. A., Wang, W., Fisher, P. J., Dykes, N. L., Corey, E., Vernier-Singer, M., Jung, S. W., Sheng, X., Hunter, L. S., McDonough, S. P., Lust, G., Bliss, S. P., Krotscheck, U., Gunn, T. M. & Todhunter, R. J., Apr 1 2011, In : American journal of veterinary research. 72, 4, p. 530-540 11 p.

Research output: Contribution to journalArticle

hip dysplasia
Hip Dislocation
osteoarthritis
Osteoarthritis
Haplotypes
2010
28 Citations (Scopus)

Differential genetic regulation of canine hip dysplasia and osteoarthritis

Zhou, Z., Sheng, X., Zhang, Z., Zhao, K., Zhu, L., Guo, G., Friedenberg, S. G., Hunter, L. S., Vandenberg-Foels, W. S., Hornbuckle, W. E., Krotscheck, U., Corey, E., Moise, N. S., Dykes, N. L., Li, J., Xu, S., Du, L., Wang, Y., Sandler, J., Acland, G. M. & 2 others, Lust, G. & Todhunter, R. J., Nov 17 2010, In : PloS one. 5, 10, e13219.

Research output: Contribution to journalArticle

Canine Hip Dysplasia
canine hip dysplasia
Hip Osteoarthritis
osteoarthritis
Genes
2009
31 Citations (Scopus)

Estimation of heritabilities, genetic correlations, and breeding values of four traits that collectively define hip dysplasia in dogs

Zhang, Z., Zhu, L., Sandler, J., Friedenberg, S. S., Egelhoff, J., Williams, A. J., Dykes, N. L., Hornbuckle, W., Krotscheck, U., Moise, S., Lust, G. & Todhunter, R. J., Apr 1 2009, In : American journal of veterinary research. 70, 4, p. 483-492 10 p.

Research output: Contribution to journalArticle

hip dysplasia
Hip Dislocation
Hip Joint
breeding value
hips
34 Citations (Scopus)

The long (and winding) road to gene discovery for canine hip dysplasia

Zhu, L., Zhang, Z., Friedenberg, S., Jung, S. W., Phavaphutanon, J., Vernier-Singer, M., Corey, E., Mateescu, R., Dykes, N., Sandler, J., Acland, G., Lust, G. & Todhunter, R., Aug 1 2009, In : Veterinary Journal. 181, 2, p. 97-110 14 p.

Research output: Contribution to journalReview article

Canine Hip Dysplasia
canine hip dysplasia
Genetic Association Studies
single nucleotide polymorphism
Single Nucleotide Polymorphism
2008
19 Citations (Scopus)

Single nucleotide polymorphisms refine QTL intervals for hip joint laxity in dogs

Zhu, L., Zhang, Z., Feng, F., Schweitzer, P., Phavaphutanon, J., Vernier-Singer, M., Corey, E., Friedenberg, S., Mateescu, R., Williams, A., Lust, G., Acland, G. & Todhunter, R., Apr 1 2008, In : Animal Genetics. 39, 2, p. 141-146 6 p.

Research output: Contribution to journalArticle

Joint Instability
Hip Joint
hips
single nucleotide polymorphism
Single Nucleotide Polymorphism
1995
46 Citations (Scopus)

Spectroscopic and kinetic properties of unphosphorylated rat hepatic phenylalanine hydroxylase expressed in Escherichia coli: Comparison of resting and activated states

Kappock, T. J., Harkins, P. C., Friedenberg, S. & Caradonna, J. P., Dec 22 1995, In : Journal of Biological Chemistry. 270, 51, p. 30532-30544 13 p.

Research output: Contribution to journalArticle

Phenylalanine Hydroxylase
Escherichia coli
Rats
Iron
Lysophosphatidylcholines
1994
8 Citations (Scopus)

Electron spin echo envelope modulation studies of water bound to tetracyanonickelate(III)

McCracken, J. & Friedenberg, S. G., Jan 1 1994, In : Journal of Physical Chemistry. 98, 2, p. 467-473 7 p.

Research output: Contribution to journalArticle

electron spin
Tensors
Protons
echoes
envelopes