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Sivaraj Sivaramakrishnan

20012023
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  • 2 Similar Profiles
Myosins Medicine & Life Sciences
Protein Kinase C Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Actins Medicine & Life Sciences
Lasers Chemical Compounds
Actin Cytoskeleton Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences

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Projects 2015 2023

Emergent cellular functions of GPCRs and myosins

Sivaramakrishnan, S.

NIH NIGMS NATL INST OF GENERAL

5/1/18 → 4/30/23

Project: Research project

Myosins

Mechanism of myosin motor-dependent filopodia formation

Titus, M. A., Courtemanche, N., Gardner, M. K. & Sivaramakrishnan, S.

NIH NIGMS NATL INST OF GENERAL

9/15/17 → 8/31/21

Project: Research project

Structural Basis of G-protein selectivity in GPCRs using

Sivaramakrishnan, S.

BECKMAN RES. INST. OF THE CITY OF HOPE

5/17/17 → 1/31/21

Project: Research project

Proteins

Development of scanning optofluidic cell lasers for high

Sivaramakrishnan, S.

University of Michigan

6/1/16 → 5/31/20

Project: Research project

Lasers

The kinase toolbox: Mapping the spatial and temporal reg

Sivaramakrishnan, S.

NIH NATIONAL CANCER INSTITUTE (NCI)

7/28/15 → 6/30/18

Project: Research project

Phosphotransferases

Research Output 2001 2019

Conformational plasticity of the intracellular cavity of GPCR−G-protein complexes leads to G-protein promiscuity and selectivity

Sandhu, M., Touma, A. M., Dysthe, M., Sadler, F., Sivaramakrishnan, S. & Vaidehi, N., Jun 11 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 24, p. 11956-11965 10 p.

Research output: Contribution to journal › Article

Gq-G11 GTP-Binding Protein alpha Subunits
GTP-Binding Proteins
Proteins
Molecular Dynamics Simulation
Adrenergic Receptors

Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism

Ma, N., Lippert, L. G., Devamani, T., Levy, B., Lee, S., Sandhu, M., Vaidehi, N. & Sivaramakrishnan, S., Nov 13 2018, In : Biochemistry. 57, 45, p. 6387-6390 4 p.

Research output: Contribution to journal › Article

Phosphotransferases
Adenosine Triphosphate
Substrates
Binding Sites
Staurosporine

Engaging myosin VI tunes motility, morphology and identity in endocytosis

Ritt, M. & Sivaramakrishnan, S., Sep 1 2018, In : Traffic. 19, 9, p. 710-722 13 p.

Research output: Contribution to journal › Article

Endocytosis
Organelles
Endosomes
Dimerization
Disintegration

Engineering synthetic myosin filaments using DNA nanotubes

Sommese, R. F. & Sivaramakrishnan, S., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 93-101 9 p. (Methods in Molecular Biology; vol. 1805).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Nanotubes
Myosins
DNA
Proteins
Dyneins
9 Citations (Scopus)

Actin turnover maintains actin filament homeostasis during cytokinetic ring contraction

Chew, T. G., Huang, J., Palani, S., Sommese, R., Kamnev, A., Hatano, T., Gu, Y., Oliferenko, S., Sivaramakrishnan, S. & Balasubramanian, M. K., Sep 1 2017, In : Journal of Cell Biology. 216, 9, p. 2657-2667 11 p.

Research output: Contribution to journal › Article

Actomyosin
Actin Cytoskeleton
Actins
Homeostasis
Myosin Type II