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Research Output 2000 2019

2019
1 Citation (Scopus)

NMR shutter-speed elucidates apparent population inversion of 1 H 2 O signals due to active transmembrane water cycling

Li, X., Mangia, S., Lee, J. H., Bai, R. & Springer, C. S., Jul 1 2019, In : Magnetic resonance in medicine. 82, 1, p. 411-424 14 p.

Research output: Contribution to journalArticle

Water
Population
Sodium-Potassium-Exchanging ATPase
Magnetic Fields
Contrast Media
2018

Capturing exchange using periodic radiofrequency irradiation

Liimatainen, T., Laakso, H., Idiyatullin, D. S., Mangia, S. & Michaeli, S., Nov 1 2018, In : Journal of Magnetic Resonance. 296, p. 79-84 6 p.

Research output: Contribution to journalArticle

Rate constants
Irradiation
irradiation
Proteins
sweep frequency
4 Citations (Scopus)

Clinical deep brain stimulation strategies for orientation-selective pathway activation

Slopsema, J. P., Peña, E., Patriat, R., Lehto, L. J., Gröhn, O., Mangia, S., Harel, N., Michaeli, S. & Johnson, M. D., Sep 5 2018, In : Journal of neural engineering. 15, 5, 056029.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Brain
Chemical activation
Electrodes
Axons

Corrigendum: Multi-modal brain MRI in subjects with PD and iRBD [Front. Neurosci, 11, (2017) (709)] DOI: 10.3389/fnins.2017.00709

Mangia, S., Svatkova, A., Mascali, D., Nissi, M. J., Burton, P. C., Bednarik, P., Auerbach, E. J., Giove, F., Eberly, L. E., Howell, M. J., Nestrasil, I., Tuite, P. J. & Michaeli, S., Jun 26 2018, In : Frontiers in Neuroscience. 12, JUN, 446.

Research output: Contribution to journalComment/debate

Open Access
Mesencephalon
Putamen
Brain
Amygdala
corrigendum
6 Citations (Scopus)

Disruption of Semantic Network in Mild Alzheimer's Disease Revealed by Resting-State fMRI

Mascali, D., DiNuzzo, M., Serra, L., Mangia, S., Maraviglia, B., Bozzali, M. & Giove, F., Feb 10 2018, In : Neuroscience. 371, p. 38-48 11 p.

Research output: Contribution to journalArticle

Open Access
Semantics
Alzheimer Disease
Magnetic Resonance Imaging
Brain
Language
3 Citations (Scopus)

Extending the Human Connectome Project across ages: Imaging protocols for the Lifespan Development and Aging projects

Harms, M. P., Somerville, L. H., Ances, B. M., Andersson, J., Barch, D. M., Bastiani, M., Bookheimer, S. Y., Brown, T. B., Buckner, R. L., Burgess, G. C., Coalson, T. S., Chappell, M. A., Dapretto, M., Douaud, G., Fischl, B., Glasser, M. F., Greve, D. N., Hodge, C., Jamison, K. W., Jbabdi, S. & 21 others, Kandala, S., Li, X., Mair, R. W., Mangia, S., Marcus, D., Mascali, D., Moeller, S., Nichols, T. E., Robinson, E. C., Salat, D. H., Smith, S. M., Sotiropoulos, S. N., Terpstra, M., Thomas, K. M., Tisdall, M. D., Ugurbil, K., van der Kouwe, A., Woods, R. P., Zöllei, L., Van Essen, D. C. & Yacoub, E., Dec 2018, In : NeuroImage. 183, p. 972-984 13 p.

Research output: Contribution to journalArticle

Connectome
Young Adult
Magnetic Resonance Imaging
Diffusion Magnetic Resonance Imaging
Neuroimaging
7 Citations (Scopus)

Neurochemical responses to chromatic and achromatic stimuli in the human visual cortex

Bednařík, P., Tkáč, I., Giove, F., Eberly, L. E., Deelchand, D. K., Barreto, F. R. & Mangia, S., Feb 1 2018, In : Journal of Cerebral Blood Flow and Metabolism. 38, 2, p. 347-359 13 p.

Research output: Contribution to journalArticle

Open Access
Visual Cortex
Color
Glucose
Electron Transport Complex IV
Aspartic Acid
3 Citations (Scopus)

Scale-invariant rearrangement of resting state networks in the human brain under sustained stimulation

Tommasin, S., Mascali, D., Moraschi, M., Gili, T., Hassan, I. E., Fratini, M., DiNuzzo, M., Wise, R. G., Mangia, S., Macaluso, E. & Giove, F., Oct 1 2018, In : NeuroImage. 179, p. 570-581 12 p.

Research output: Contribution to journalArticle

Brain
Short-Term Memory
2017
10 Citations (Scopus)
Open Access
Astrocytes
Energy Metabolism
Neurons
Glutamic Acid
Brain

Conceptual design of flex-DBS, a mechanically reconfigurable deep brain stimulation probe

Johnson, G., Lehto, L., Mangia, S., Gröhn, O., Michaeli, S. & Kodandaramaiah, S., Jan 1 2017, Frontiers in Biomedical Devices, BIOMED - 2017 Design of Medical Devices Conference, DMD 2017. American Society of Mechanical Engineers, (Frontiers in Biomedical Devices, BIOMED - 2017 Design of Medical Devices Conference, DMD 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Conceptual design
Brain
1 Citation (Scopus)

Effects of reduced oxygen availability on the vascular response and oxygen consumption of the activated human visual cortex

Rodrigues Barreto, F., Mangia, S. & Garrido Salmon, C. E., Jul 1 2017, In : Journal of Magnetic Resonance Imaging. 46, 1, p. 142-149 8 p.

Research output: Contribution to journalArticle

Visual Cortex
Oxygen Consumption
Blood Vessels
Oxygen
Cerebrovascular Circulation
1 Citation (Scopus)

Lysophosphatidyl choline induced demyelination in rat probed by relaxation along a fictitious field in high rank rotating frame

Lehto, L. J., Albors, A. A., Sierra, A., Tolppanen, L., Eberly, L. E., Mangia, S., Nurmi, A., Michaeli, S. & Gröhn, O., Aug 3 2017, In : Frontiers in Neuroscience. 11, AUG, 433.

Research output: Contribution to journalArticle

Open Access
Demyelinating Diseases
Myelin Sheath
Choline
Diffusion Tensor Imaging
Gliosis
2 Citations (Scopus)

MB-SWIFT functional MRI during deep brain stimulation in rats

Lehto, L. J., Idiyatullin, D., Zhang, J., Utecht, L., Adriany, G., Garwood, M., Gröhn, O., Michaeli, S. & Mangia, S., Oct 1 2017, In : NeuroImage. 159, p. 443-448 6 p.

Research output: Contribution to journalArticle

Open Access
Deep Brain Stimulation
Magnetic Resonance Imaging
Echo-Planar Imaging
Brain
Artifacts
2 Citations (Scopus)

Multi-modal brain MRI in subjects with PD and iRBD

Mangia, S., Svatkova, A., Mascali, D., Nissi, M. J., Burton, P. C., Bednarik, P., Auerbach, E. J., Giove, F., Eberly, L. E., Howell, M. J., Nestrasil, I., Tuite, P. J. & Michaeli, S., Dec 19 2017, In : Frontiers in Neuroscience. 11, DEC, 709.

Research output: Contribution to journalArticle

Open Access
Parkinson Disease
Magnetic Resonance Imaging
Brain
Diffusion Tensor Imaging
REM Sleep Behavior Disorder
12 Citations (Scopus)

Orientation selective deep brain stimulation

Lehto, L. J., Slopsema, J. P., Johnson, M. D., Shatillo, A., Teplitzky, B. A., Utecht, L., Adriany, G., Mangia, S., Sierra, A., Low, W. C., Gröhn, O. & Michaeli, S., Feb 2017, In : Journal of neural engineering. 14, 1, 016016.

Research output: Contribution to journalArticle

Open Access
Deep Brain Stimulation
Brain
Electric fields
Axons
Magnetic Resonance Imaging
3 Citations (Scopus)

Task-Related modulations of BOLD low-frequency fluctuations within the default mode Network

Tommasin, S., Mascali, D., Gili, T., Assan, I. E., Moraschi, M., Fratini, M., Wise, R. G., Macaluso, E., Mangia, S. & Giove, F., Jul 25 2017, In : Frontiers in Physics. 5, JUL, 31.

Research output: Contribution to journalArticle

Oxygenation
oxygenation
blood
Blood
Low Frequency
1 Citation (Scopus)

Temporal information entropy of the blood-oxygenation level-dependent signals increases in the activated human primary visual cortex

DiNuzzo, M., Mascali, D., Moraschi, M., Bussu, G., Maraviglia, B., Mangia, S. & Giove, F., Feb 23 2017, In : Frontiers in Physics. 5, FEB, 7.

Research output: Contribution to journalArticle

Open Access
Visual Cortex
Oxygenation
Information Entropy
cortexes
oxygenation
9 Citations (Scopus)

Type 1 diabetes and impaired awareness of hypoglycemia are associated with reduced brain gray matter volumes

Bednarik, P., Moheet, A. A., Grohn, H., Kumar, A. F., Eberly, L. E., Seaquist, E. R. & Mangia, S., Sep 25 2017, In : Frontiers in Neuroscience. 11, SEP, 529.

Research output: Contribution to journalArticle

Open Access
Type 1 Diabetes Mellitus
Hypoglycemia
Frontal Lobe
Brain
Parietal Lobe
2016
4 Citations (Scopus)

Effect of collagen cross-linking on quantitative MRI parameters of articular cartilage

Rautiainen, J., Nieminen, M. T., Salo, E. N., Kokkonen, H. T., Mangia, S., Michaeli, S., Gröhn, O., Jurvelin, J. S., Töyräs, J. & Nissi, M. J., Sep 1 2016, In : Osteoarthritis and Cartilage. 24, 9, p. 1656-1664 9 p.

Research output: Contribution to journalArticle

Cartilage
Articular Cartilage
Magnetic resonance
Collagen
Magnetic Resonance Imaging
11 Citations (Scopus)

MRI relaxation in the presence of fictitious fields correlates with myelin content in normal rat brain

Hakkarainen, H., Sierra, A., Mangia, S., Garwood, M., Michaeli, S., Gröhn, O. & Liimatainen, T., Jan 1 2016, In : Magnetic resonance in medicine. 75, 1, p. 161-168 8 p.

Research output: Contribution to journalArticle

Myelin Sheath
Brain
Iron
Cell Count
Brain Diseases
15 Citations (Scopus)

Multi-parametric MRI characterization of enzymatically degraded articular cartilage

Nissi, M. J., Salo, E. N., Tiitu, V., Liimatainen, T., Michaeli, S., Mangia, S., Ellermann, J. & Nieminen, M. T., Jul 1 2016, In : Journal of Orthopaedic Research. 34, 7, p. 1111-1120 10 p.

Research output: Contribution to journalArticle

Articular Cartilage
Glycosaminoglycans
Collagen
Cartilage
Chondroitin ABC Lyase
2015
5 Citations (Scopus)

Assessment of dysmyelination with RAFFn MRI: Application to murine MPS I

Satzer, D., DiBartolomeo, C., Ritchie, M. M., Storino, C., Liimatainen, T., Hakkarainen, H., Idiyatullin, D., Mangia, S., Michaeli, S., Parr, A. M. & Low, W. C., Feb 13 2015, In : PloS one. 10, 2, e0116788.

Research output: Contribution to journalArticle

mucopolysaccharidosis
Mucopolysaccharidoses
Magnetic resonance imaging
Relaxation time
myelin sheath
12 Citations (Scopus)

Does abnormal glycogen structure contribute to increased susceptibility to seizures in epilepsy?

DiNuzzo, M., Mangia, S., Maraviglia, B. & Giove, F., Feb 1 2015, In : Metabolic Brain Disease. 30, 1, p. 307-316 10 p.

Research output: Contribution to journalArticle

Glycogen
Glutamic Acid
Epilepsy
Seizures
Astrocytes
77 Citations (Scopus)

Impact of diabetes on cognitive function and brain structure

Moheet, A., Mangia, S. & Seaquist, E. R., Sep 1 2015, In : Annals of the New York Academy of Sciences. 1353, 1, p. 60-71 12 p.

Research output: Contribution to journalArticle

Medical problems
Cognition
Brain
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
10 Citations (Scopus)

Monoaminergic Control of Cellular Glucose Utilization by Glycogenolysis in Neocortex and Hippocampus

DiNuzzo, M., Giove, F., Maraviglia, B. & Mangia, S., Dec 1 2015, In : Neurochemical Research. 40, 12, p. 2493-2504 12 p.

Research output: Contribution to journalArticle

Glycogenolysis
Neocortex
Hippocampus
Glucose-6-Phosphate
Glycogen
19 Citations (Scopus)

MRI contrasts in high rank rotating frames

Liimatainen, T., Hakkarainen, H., Mangia, S., Huttunen, J. M. J., Storino, C., Idiyatullin, D., Sorce, D., Garwood, M. & Michaeli, S., Jan 1 2015, In : Magnetic resonance in medicine. 73, 1, p. 254-262 9 p.

Research output: Contribution to journalArticle

Magnetic Fields
Brain
White Matter
Gray Matter
8 Citations (Scopus)

Naltrexone for treatment of impaired awareness of hypoglycemia in type 1 diabetes: A randomized clinical trial

Moheet, A., Mangia, S., Kumar, A., Tesfaye, N., Eberly, L. E., Bai, Y., Kubisiak, K. & Seaquist, E. R., Nov 2015, In : Journal of Diabetes and Its Complications. 29, 8, p. 1277-1282 6 p.

Research output: Contribution to journalArticle

Naltrexone
Type 1 Diabetes Mellitus
Hypoglycemia
Randomized Controlled Trials
Therapeutics
64 Citations (Scopus)

Neurochemical and BOLD responses during neuronal activation measured in the human visual cortex at 7 Tesla

Bednarik, P., Tkac, I., Giove, F., Dinuzzo, M., Deelchand, D. K., Emir, U. E., Eberly, L. E. & Mangia, S., Mar 31 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, p. 601-610 10 p.

Research output: Contribution to journalArticle

Visual Cortex
Magnetic Resonance Imaging
Glutamic Acid
Lactic Acid
Aspartic Acid
2014
1 Citation (Scopus)

Exchange-induced relaxation in the presence of a fictitious field

Sorce, D. J., Mangia, S., Liimatainen, T., Garwood, M. & Michaeli, S., Jan 1 2014, In : Journal of Magnetic Resonance. 245, p. 12-16 5 p.

Research output: Contribution to journalArticle

Magnetic Fields
Magnetic resonance imaging
Tumors
Ion exchange
tumors
14 Citations (Scopus)
Multiple Sclerosis
Relapsing-Remitting Multiple Sclerosis
Patents
Lateral Ventricles
Magnetic Resonance Spectroscopy
27 Citations (Scopus)

Physiological bases of the K+ and the glutamate/GABA hypotheses of epilepsy

DiNuzzo, M., Mangia, S., Maraviglia, B. & Giove, F., Jan 1 2014, In : Epilepsy Research. 108, 6, p. 995-1012 18 p.

Research output: Contribution to journalReview article

gamma-Aminobutyric Acid
Glutamic Acid
Epilepsy
Seizures
Glutamate-Ammonia Ligase
2013
10 Citations (Scopus)
Carrier State
Facilitative Glucose Transport Proteins
Deoxyglucose
Metabolism
Protein Isoforms
7 Citations (Scopus)

K+ homeostasis in the Brain: A new role for glycogenolysis

Mangia, S., Giove, F. & Dinuzzo, M., Mar 1 2013, In : Neurochemical Research. 38, 3, p. 470-471 2 p.

Research output: Contribution to journalReview article

Glycogenolysis
Glycogen
Brain
Homeostasis
Astrocytes
24 Citations (Scopus)

MRI rotating frame relaxation measurements for articular cartilage assessment

Ellermann, J., Ling, W., Nissi, M. J., Arendt, E., Carlson, C. S., Garwood, M., Michaeli, S. & Mangia, S., Nov 1 2013, In : Magnetic Resonance Imaging. 31, 9, p. 1537-1543 7 p.

Research output: Contribution to journalArticle

Cartilage
Articular Cartilage
Magnetic resonance imaging
Trypsin
Magnetization
20 Citations (Scopus)

Neurochemical profile of patients with type 1 diabetes measured by 1H-MRS at 4 T

Mangia, S., Kumar, A. F., Moheet, A., Roberts, R. J., Eberly, L. E., Seaquist, E. R. & Tkac, I., May 1 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 5, p. 754-759 6 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Occipital Lobe
Brain
Body Mass Index
Proton Magnetic Resonance Spectroscopy
21 Citations (Scopus)

Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes

Dinuzzo, M., Mangia, S., Maraviglia, B. & Giove, F., Sep 11 2013, In : Neurochemistry International. 63, 5, p. 458-464 7 p.

Research output: Contribution to journalReview article

Glycogenolysis
Glycogen
Astrocytes
Brain
Ion Transport
2012
36 Citations (Scopus)

Cortical metabolites as biomarkers in the R6/2 model of Huntington's disease

Zacharoff, L., Tkac, I., Song, Q., Tang, C., Bolan, P. J., Mangia, S., Henry, P-G., Li, T. & Dubinsky, J. M., Mar 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 3, p. 502-514 13 p.

Research output: Contribution to journalArticle

Huntington Disease
Biomarkers
Disease Progression
Brain
Magnetic Resonance Spectroscopy
8 Citations (Scopus)

Heteronuclear adiabatic relaxation dispersion (hard) for quantitative analysis of conformational dynamics in proteins

Traaseth, N. J., Chao, F. A., Masterson, L. R., Mangia, S., Garwood, M., Michaeli, S., Seelig, B. & Veglia, G., Jun 1 2012, In : Journal of Magnetic Resonance. 219, p. 75-82 8 p.

Research output: Contribution to journalArticle

quantitative analysis
proteins
Chemical analysis
Proteins
Rate constants
23 Citations (Scopus)

Hypoglycemia-induced increases in thalamic cerebral blood flow are blunted in subjects with type 1 diabetes and hypoglycemia unawareness

Mangia, S., Tesfaye, N., De Martino, F., Kumar, A. F., Kollasch, P., Moheet, A., Eberly, L. E. & Seaquist, E. R., Nov 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 11, p. 2084-2090 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Type 1 Diabetes Mellitus
Hypoglycemia
Thalamus
Blood Glucose
9 Citations (Scopus)
Brain Stem
Parkinson Disease
Magnetic Resonance Imaging
Mesencephalon
Pathology
43 Citations (Scopus)

Metabolic pathways and activity-dependent modulation of glutamate concentration in the human brain

Mangia, S., Giove, F. & DiNuzzo, M., Nov 1 2012, In : Neurochemical Research. 37, 11, p. 2554-2561 8 p.

Research output: Contribution to journalReview article

Metabolic Networks and Pathways
Glutamic Acid
Brain
Modulation
Neurotransmitter Agents
47 Citations (Scopus)

The role of astrocytic glycogen in supporting the energetics of neuronal activity

DiNuzzo, M., Mangia, S., Maraviglia, B. & Giove, F., Nov 1 2012, In : Neurochemical Research. 37, 11, p. 2432-2438 7 p.

Research output: Contribution to journalReview article

Glycogen
Metabolism
Astrocytes
Glucose
Neurons
15 Citations (Scopus)

Toward understanding transverse relaxation in human brain through its field dependence

Mitsumori, F., Watanabe, H., Takaya, N., Garwood, M., Auerbach, E. J., Michaeli, S. & Mangia, S., Sep 1 2012, In : Magnetic resonance in medicine. 68, 3, p. 947-953 7 p.

Research output: Contribution to journalArticle

Magnetic Fields
Brain
Ferritins
Least-Squares Analysis
Protons
2011
5 Citations (Scopus)
Creatine
Metabolites
Protons
Rate constants
Brain
17 Citations (Scopus)

Magnetization transfer using inversion recovery during off-resonance irradiation

Mangia, S., De Martino, F., Liimatainen, T., Garwood, M. & Michaeli, S., Dec 1 2011, In : Magnetic Resonance Imaging. 29, 10, p. 1346-1350 5 p.

Research output: Contribution to journalArticle

Magnetization
Irradiation
Recovery
Organ Specificity
Neuroimaging
20 Citations (Scopus)

Relaxation dispersion in MRI induced by fictitious magnetic fields

Liimatainen, T., Mangia, S., Ling, W., Ellermann, J., Sorce, D. J., Garwood, M. & Michaeli, S., Apr 1 2011, In : Journal of Magnetic Resonance. 209, 2, p. 269-276 8 p.

Research output: Contribution to journalArticle

Magnetic Fields
Magnetic resonance imaging
Magnetic fields
magnetic fields
Amplitude modulation
65 Citations (Scopus)

Response to comment on recent modeling studies of astrocyte-neuron metabolic interactions: Much ado about nothing

Mangia, S., Dinuzzo, M., Giove, F., Carruthers, A., Simpson, I. A. & Vannucci, S. J., Jun 1 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 6, p. 1346-1353 8 p.

Research output: Contribution to journalReview article

Astrocytes
Lactic Acid
Neurons
Glucose
Synaptic Transmission
2010
62 Citations (Scopus)

Changes in glucose uptake rather than lactate shuttle take center stage in subserving neuroenergetics: Evidence from mathematical modeling

Dinuzzo, M., Mangia, S., Maraviglia, B. & Giove, F., Mar 1 2010, In : Journal of Cerebral Blood Flow and Metabolism. 30, 3, p. 586-602 17 p.

Research output: Contribution to journalArticle

Lactic Acid
Glucose
Astrocytes
Neurons
Brain
64 Citations (Scopus)
Glycogenolysis
Glycogen
Astrocytes
Blood Glucose
Lactic Acid