Sergio Gradilone

Associate Professor, Hormel Institute

Emailsgradilo@umn.edu

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Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

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1 Active
2 Finished

The cholangiocyte primary cilium as a tumor suppressor o
Gradilone, S.
NIH NATIONAL CANCER INSTITUTE (NCI)
7/1/15 → 6/30/21
Project: Research project
HDAC6 and Pancreas Cancer
Gradilone, S.
MAYO CLINIC - JACKSONVILLE
6/1/16 → 5/31/17
Project: Research project
Primary cilia and malignant transformation
Gradilone, S.
NIH NATIONAL CANCER INSTITUTE (NCI)
1/27/15 → 9/30/15
Project: Research project

34 Article
8 Review article
1 Comment/debate
1 Editorial
More
- 1 Letter

Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease
Caballero-Camino, F. J., Rivilla, I., Herraez, E., Briz, O., Santos-Laso, A., Izquierdo-Sanchez, L., Lee-Law, P. Y., Rodrigues, P. M., Munoz-Garrido, P., Jin, S., Peixoto, E., Richard, S., Gradilone, S. A., Perugorria, M. J., Esteller, M., Bujanda, L., Marin, J. J. G., Banales, J. M. & Cossío, F. P., Jan 2021, In: Hepatology. 73, 1, p. 186-203 18 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Banales, J. M., Marin, J. J. G., Lamarca, A., Rodrigues, P. M., Khan, S. A., Roberts, L. R., Cardinale, V., Carpino, G., Andersen, J. B., Braconi, C., Calvisi, D. F., Perugorria, M. J., Fabris, L., Boulter, L., Macias, R. I. R., Gaudio, E., Alvaro, D., Gradilone, S. A., Strazzabosco, M., Marzioni, M. & 14 others, Coulouarn, C., Fouassier, L., Raggi, C., Invernizzi, P., Mertens, J. C., Moncsek, A., Rizvi, S., Heimbach, J., Koerkamp, B. G., Bruix, J., Forner, A., Bridgewater, J., Valle, J. W. & Gores, G. J., Sep 1 2020, In: Nature Reviews Gastroenterology and Hepatology. 17, 9, p. 557-588 32 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
59 Scopus citations
HDAC6-dependent ciliophagy is involved in ciliary loss and cholangiocarcinoma growth in human cells and murine models
Peixoto, E., Jin, S., Thelen, K., Biswas, A., Richard, S., Morleo, M., Mansini, A., Holtorf, S., Carbone, F., Pastore, N., Ballabio, A., Franco, B. & Gradilone, S. A., Jun 2020, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 318, 6, p. G1022-G1033
Research output: Contribution to journal › Article › peer-review
7 Scopus citations
Role of Glucose Metabolism Reprogramming in the Pathogenesis of Cholangiocarcinoma
Pant, K., Richard, S., Peixoto, E. & Gradilone, S. A., Apr 3 2020, In: Frontiers in Medicine. 7, 113.
Research output: Contribution to journal › Review article › peer-review

Open Access
3 Scopus citations
The primary cilium: Its role as a tumor suppressor organelle
Peixoto, E., Richard, S., Pant, K., Biswas, A. & Gradilone, S. A., May 2020, In: Biochemical Pharmacology. 175, 113906.
Research output: Contribution to journal › Review article › peer-review
3 Scopus citations

HI’s Dr. Sergio Gradilone invited to join NIH study section
Sergio Gradilone
8/19/20
1 item of Media coverage
Press/Media: Expert Comment
HI researchers further cancer research online
Ilana Chefetz Menaker, Sergio Gradilone, Shujun Liu & Luke H Hoeppner
7/15/20
1 item of Media coverage
Press/Media: Research