Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External Positions
Research Collaborator, Mayo Clinic
Jun 1 2015 → …
Member, Masonic Cancer Center
Jan 6 2015 → …
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Collaborations and top research areas from the last five years
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Primary cilia loss in bile duct cells; the interplay with the autophagy machinery
Gradilone, S. (PI)
NIH NATL INST OF DIABETES/DIG/KIDNEY DIS
2/1/23 → 1/31/27
Project: Research project
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The cholangiocyte primary cilium as a tumor suppressor o
Gradilone, S. (PI)
NIH NATIONAL CANCER INSTITUTE (NCI)
7/1/15 → 6/30/21
Project: Research project
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Primary cilia and malignant transformation
Gradilone, S. (PI)
NIH NATIONAL CANCER INSTITUTE (NCI)
1/27/15 → 9/30/15
Project: Research project
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Histone Deacetylase SIRT1 promotes loss of primary cilia in Cholangiocarcinoma
Pant, K., Peixoto, E., Richard, S., Biswas, A. S., O’Sullivan, M. G., Giama, N., Ha, Y., Yin, J., Carotenuto, P., Salati, M., Ren, Y., Yang, R., Franco, B., Roberts, L. R. & Gradilone, S. A., Jul 29 2021, In: Hepatology. 74, 6, p. 3235-3248 14 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
HDAC6-dependent ciliophagy is involved in ciliary loss and cholangiocarcinoma growth in human cells and murine models
Peixoto, E., Jin, S., Thelen, K., Biswas, A. S., Richard, S., Morleo, M., Mansini, A., Holtorf, S., Carbone, F., Pastore, N., Ballabio, A., Franco, B. & Gradilone, S. A., Jun 2020, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 318, 6, p. G1022-G1033Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
The Chemosensory Function of Primary Cilia Regulates Cholangiocyte Migration, Invasion, and Tumor Growth
Mansini, A. P., Peixoto, E., Jin, S., Richard, S. & Gradilone, S., Apr 2019, In: Hepatology. 69, 4, p. 1582-1598 17 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma
Mansini, A. P., Lorenzo Pisarello, M. J., Thelen, K. M., Cruz-Reyes, M., Peixoto, E., Jin, S., Howard, B. N., Trussoni, C. E., Gajdos, G. B., LaRusso, N. F., Perugorria, M. J., Banales, J. M. & Gradilone, S. A., Aug 2018, In: Hepatology. 68, 2, p. 561-573 13 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Banales, J. M., Marin, J. J. G., Lamarca, A., Rodrigues, P. M., Khan, S. A., Roberts, L. R., Cardinale, V., Carpino, G., Andersen, J. B., Braconi, C., Calvisi, D. F., Perugorria, M. J., Fabris, L., Boulter, L., Macias, R. I. R., Gaudio, E., Alvaro, D., Gradilone, S. A., Strazzabosco, M. & Marzioni, M. & 14 others, , Sep 1 2020, In: Nature Reviews Gastroenterology and Hepatology. 17, 9, p. 557-588 32 p.Research output: Contribution to journal › Review article › peer-review
Open Access1511 Scopus citations
Press/Media
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HI’s Dr. Sergio Gradilone invited to join NIH study section
8/19/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
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HI researchers further cancer research online
Chefetz Menaker, I., Gradilone, S., Liu, S. & Hoeppner, L. H.
7/15/20
1 item of Media coverage
Press/Media: Research