Projects per year
Personal profile
Research Interests
Current research interests and long-term scientific goals of the laboratory revolve around the plasticity and regeneration of skeletal muscle, in efforts to mitigate the devastating functional limitations of limb salvage and traumatic muscle injuries. The laboratory examines the musculoskeletal and neuromuscular systems in efforts to understand and develop effective strategies to address the deleterious effects complex traumatic muscle injuries, namely volumetric muscle loss. Ongoing work broadly encompasses investigating muscle and nerve interactions, metabolic and fibrotic comorbidities, regenerative rehabilitation treatment strategies, and the combination of these in more complex orthopaedic injuries.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 17 Partnerships for the Goals
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Collaborations and top research areas from the last five years
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Advancing regenerative rehabilitation following muscle injury to optimize health and readiness
Greising, S. (PI) & Lillquist, T. (Other Role)
MEDICAL TECHNOLOGY ENTERPRISE CONSORTIUM, U.S. DEPARTMENT OF DEFENSE
11/14/25 → 5/13/27
Project: Research project
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Age, Injury, and the Neuromuscular Junction
Greising, S. (PI)
NIH NATIONAL INSTITUTE ON AGING
8/1/23 → 7/31/27
Project: Research project
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Interdisciplinary Musculoskeletal Research Training Program
Bradley, E. W. (PI), Greising, S. (Co-Principal Investigator), Johnson, C. P. (Co-Principal Investigator) & Mansky, K. (Co-Principal Investigator)
NIH NIAMS NATIONALL INSTITUTE OF ARTHRIT
8/20/25 → 7/31/26
Project: Research project
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Advancing regenerative rehabilitation following muscle injury to optimize health and readiness
Greising, S. (PI) & Lillquist, T. (Other Role)
ADVANCED TECHNOLOGY INTERNATIONAL, U.S. DEPARTMENT OF DEFENSE
5/20/25 → 11/13/25
Project: Research project
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Nerve Degeneration and Recovery after PEG Fusion
Greising, S. (PI) & Lillquist, T. (Other Role)
9/1/24 → 2/28/26
Project: Research project
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17β-Estradiol mitigates ovariectomy-induced defects in mitochondrial bioenergetics and redox balance after VML injury in female mice
Heo, J., Miller, D. L., Hoffman, J. R., Groover, R. M., Greising, S. M. & Call, J. A., Jul 2026, In: American Journal of Physiology - Cell Physiology. 331, 1, p. C205-C221Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Loss of ovarian hormones modulates sex-specific metabolic adaptations to volumetric muscle loss
Bruzina, A. S., Juckett, W. T., Mozafari, F., Freeman, C. G., Call, J. A. & Greising, S. M., Jul 2026, In: American Journal of Physiology - Cell Physiology. 331, 1, p. C117-C136Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
New paradigm for old hormones: the case for 17a-estradiol as an acute therapeutic in male volumetric muscle loss
Call, J. A., Juckett, W. T., Montgomery, M. M. & Greising, S. M., Oct 2026, In: American Journal of Physiology - Cell Physiology. 331, 4, p. C960-C964Research output: Contribution to journal › Article › peer-review
Open Access -
Novel assessment of postprandial metabolism reveals sex-specific metabolic flexibility and lipid remodeling following volumetric muscle loss
Bruzina, A. S., Crum, B. A., Goodman, L. A., Ng, Y. E., Hawe, R. L., Call, J. A. & Greising, S. M., 2026, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 330, 2, p. R243-R260Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
When rehabilitation is not enough, how targeting metabolism can overcome the limited plasticity of skeletal muscle after traumatic injury
Greising, S. M. & Call, J. A., Apr 1 2026, In: Experimental Physiology. 111, 4, p. 1718-1732 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access