Personal profile
Research Interests
Current research interests and long-term scientific goals of the laboratory revolve around the plasticity and regeneration of skeletal muscle, in efforts to mitigate the devastating functional limitations of limb salvage and traumatic muscle injuries. The laboratory examines the musculoskeletal and neuromuscular systems in efforts to understand and develop effective strategies to address the deleterious effects complex traumatic muscle injuries, namely volumetric muscle loss. Ongoing work broadly encompasses investigating muscle and nerve interactions, metabolic and fibrotic comorbidities, regenerative rehabilitation treatment strategies, and the combination of these in more complex orthopaedic injuries.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 17 Partnerships for the Goals
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Collaborations and top research areas from the last five years
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Advancing regenerative rehabilitation following muscle injury to optimize health and readiness
Greising, S. (PI) & Lillquist, T. (Other Role)
MEDICAL TECHNOLOGY ENTERPRISE CONSORTIUM, U.S. DEPARTMENT OF DEFENSE
11/14/25 → 5/13/27
Project: Research project
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Interdisciplinary Musculoskeletal Research Training Program
Bradley, E. W. (PI), Greising, S. (Co-Principal Investigator), Johnson, C. P. (Co-Principal Investigator) & Mansky, K. (Co-Principal Investigator)
NIH NIAMS NATIONALL INSTITUTE OF ARTHRIT
8/20/25 → 7/31/26
Project: Research project
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Age, Injury, and the Neuromuscular Junction
Greising, S. (PI)
NIH NATIONAL INSTITUTE ON AGING
8/1/23 → 7/31/27
Project: Research project
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Pathological foundations of skeletal muscle after volumetric muscle loss injury and targets for rehabilitation
Greising, S. (PI)
THE UNIVERSITY OF GEORGIA, NATIONAL INSTITUTES OF HEALTH (NIH)
4/1/22 → 8/31/26
Project: Research project
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Pathological foundations of skeletal muscle after volumetric muscle loss injury and targets for rehabilitation
Greising, S. (PI)
THE UNIVERSITY OF GEORGIA, NATIONAL INSTITUTES OF HEALTH (NIH)
4/1/22 → 3/31/26
Project: Research project
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Novel assessment of postprandial metabolism reveals sex-specific metabolic flexibility and lipid remodeling following volumetric muscle loss
Bruzina, A. S., Crum, B. A., Goodman, L. A., Ng, Y. E., Hawe, R. L., Call, J. A. & Greising, S. M., Feb 1 2026, In: American journal of physiology. Regulatory, integrative and comparative physiology. 330, 2, p. R243-R260Research output: Contribution to journal › Article › peer-review
Open Access -
Accumulation of lipids after acute direct and indirect traumatic injuries in male and female mice
Bruzina, A. S., Crum, B. A., Raymond-Pope, C. J., Call, J. A. & Greising, S. M., Dec 2025, In: BMC Musculoskeletal Disorders. 26, 1, 932.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Acute mitochondrial reactive oxygen species emissions drive mitochondrial dysfunction after traumatic muscle injury in male mice
Heo, J., Miller, D. L., Hoffman, J. R., Oberholtzer, E., Castelli, K. M., Sparagna, G. C., Fisher-Wellman, K. H., Greising, S. M. & Call, J. A., Jul 2025, In: American Journal of Physiology - Cell Physiology. 329, 1, p. C235-C250Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Advancing β-adrenoreceptor agonism for recovery after volumetric muscle loss through regenerative rehabilitation and biomaterial delivery approaches
McFaline-Figueroa, J., Raymond-Pope, C. J., Pearson, J. J., Schifino, A. G., Heo, J., Lillquist, T. J., Pritchard, E. E., Winders, E. A., Hunda, E. T., Temenoff, J. S., Greising, S. M. & Call, J. A., 2025, In: Regenerative Biomaterials. 12, rbaf015.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
CORP: In vivo muscle strength—perspectives on the design and interpretation of preclinical animal studies
Call, J. A., Greising, S. M. & Baumann, C. W., Nov 6 2025, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 329, 5, p. R753-R770Research output: Contribution to journal › Article › peer-review
Open Access