Projects per year
Personal profile
Research Interests
Current research interests and long-term scientific goals of the laboratory revolve around the plasticity and regeneration of skeletal muscle, in efforts to mitigate the devastating functional limitations of limb salvage and traumatic muscle injuries. The laboratory examines the musculoskeletal and neuromuscular systems in efforts to understand and develop effective strategies to address the deleterious effects complex traumatic muscle injuries, namely volumetric muscle loss. Ongoing work broadly encompasses investigating muscle and nerve interactions, metabolic and fibrotic comorbidities, regenerative rehabilitation treatment strategies, and the combination of these in more complex orthopaedic injuries.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Skeletal muscle properties after various tone management approaches in individuals with cerebral palsy
GILLETTE CHILDREN'S SPECIALTY CARE
10/27/20 → 10/26/22
Project: Research project
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Regenerative rehabilitation solutions to improve functional limitations and plasticity following volumetric muscle loss
9/15/20 → 9/14/24
Project: Research project
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Early interventions to address functional limitations and comorbidities to volumetric muscle loss
9/15/18 → 9/14/22
Project: Research project
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Neurocentric Enhancement of Skeletal Muscle Function for the Treatment of Volumetric Muscle Loss
US ARMY MED RESEARCH & MATERIEL COMMAND
3/1/19 → 2/28/22
Project: Research project
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Commentaries on Viewpoint: The academic biomedical research laboratory as a “small business”: “Partnering small businesses” for success
Call, J. A. & Greising, S. M., Aug 1 2021, In: Journal of applied physiology. 131, 2, p. 744 3 p.Research output: Contribution to journal › Letter › peer-review
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Humanized skeletal muscle in MYF5/MYOD/MYF6-null pig embryos
Maeng, G., Das, S., Greising, S., Gong, W., Singh, B. N., Kren, S., Mickelson, D., Skie, E., Gafni, O., Sorensen, J. R., Weaver, C. V., Garry, D. J. & Garry, M. G., Aug 2021, In: Nature Biomedical Engineering. 5, 8, p. 805-814 10 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Independent of physical activity, volumetric muscle loss injury in a murine model impairs whole-body metabolism
Dalske, K. A., Raymond-Pope, C. J., McFaline-Figueroa, J., Basten, A. M., Call, J. A. & Greising, S. M., Jun 2021, In: PloS one. 16, 6 June, e0253629.Research output: Contribution to journal › Article › peer-review
Open Access -
In vivo measurement of hindlimb dorsiflexor isometric torque from pig
Corona, B. T., Call, J. A., Borkowski, M. & Greising, S. M., 2021, In: Journal of Visualized Experiments. 2021, 175, e62905.Research output: Contribution to journal › Article › peer-review
Open Access -
Lifelong ulk1-mediated autophagy deficiency in muscle induces mitochondrial dysfunction and contractile weakness
Nichenko, A. S., Sorensen, J. R., Southern, W. M., Qualls, A. E., Schifino, A. G., McFaline-Figueroa, J., Blum, J. E., Tehrani, K. F., Yin, H., Mortensen, L. J., Thalacker-Mercer, A. E., Greising, S. M. & Call, J. A., Feb 2 2021, In: International journal of molecular sciences. 22, 4, p. 1-20 20 p., 1937.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations