Sara L Zimmer

PhD, Duluth Campus Faculty Liaison to the Medical School Office of Faculty Affairs

Accepting PhD Students

PhD projects

Gene regulation and metabolism in kinetoplastids (trypanosomatid parasites)

Willing to speak to media

20012020

Research output per year

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Research Output

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Article
2020

A global analysis of enzyme compartmentalization to glycosomes

Durrani, H., Hampton, M., Rumbley, J. N. & Zimmer, S. L., Jan 1 2020, In : Pathogens. 9, 4, 281.

Research output: Contribution to journalArticle

Open Access

A link between mitochondrial gene expression and life stage morphologies in Trypanosoma cruzi

Ramirez-Barrios, R., Susa, E. K., Smoniewski, C. M., Faacks, S. P., Liggett, C. K. & Zimmer, S. L., Jan 1 2020, (Accepted/In press) In : Molecular Microbiology.

Research output: Contribution to journalArticle

2018

Gene expression to mitochondrial metabolism: Variability among cultured Trypanosoma cruzi strains

Kalem, M. C., Gerasimov, E. S., Vu, P. K. & Zimmer, S. L., May 2018, In : PloS one. 13, 5, e0197983.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
4 Scopus citations

Trypanosomatid mitochondrial RNA editing: Dramatically complex transcript repertoires revealed with a dedicated mapping tool

Gerasimov, E. S., Gasparyan, A. A., Kaurov, I., Tichý, B., Logacheva, M. D., Kolesnikov, A. A., Lukeš, J., Yurchenko, V., Zimmer, S. L. & Flegontov, P., Jan 25 2018, In : Nucleic acids research. 46, 2, p. 765-781 17 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2017

A putative ATP/GTP binding protein affects Leishmania mexicana growth in insect vectors and vertebrate hosts

Ishemgulova, A., Kraeva, N., Hlaváčová, J., Zimmer, S. L., Butenko, A., Podešvová, L., Leštinová, T., Lukeš, J., Kostygov, A., Votýpka, J., Volf, P. & Yurchenko, V., Jul 24 2017, In : PLoS neglected tropical diseases. 11, 7, e0005782.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

The interaction of a Trypanosoma brucei KH-domain protein with a ribonuclease is implicated in ribosome processing

Kala, S., Mehta, V., Yip, C. W., Moshiri, H., Najafabadi, H. S., Ma, R., Nikpour, N., Zimmer, S. L. & Salavati, R., Jan 1 2017, In : Molecular and Biochemical Parasitology. 211, p. 94-103 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

CircTAIL-seq, a targeted method for deep analysis of RNA 3' tails, reveals transcript-specific differences by multiple metrics

Gazestani, V. H., Hampton, M., Abrahante, J. E., Salavati, R. & Zimmer, S. L., Mar 2016, In : RNA. 22, 3, p. 477-486 10 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Mitochondrial Gene Expression Is Responsive to Starvation Stress and Developmental Transition in Trypanosoma cruzi

Shaw, A. K., Kalem, M. C. & Zimmer, S. L., Apr 2016, In : mSphere. 1, 2, p. e00051-16 e00051-16.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
2013

Ribosome biogenesis requires a highly diverged XRN family 5′→3′ exoribonuclease for rRNA processing in Trypanosoma brucei

Sakyiama, J., Zimmer, S. L., Ciganda, M., Williams, N. & Read, L. K., Oct 1 2013, In : RNA. 19, 10, p. 1419-1431 13 p.

Research output: Contribution to journalArticle

8 Scopus citations
2012

Additive and transcript-specific effects of KPAP1 and TbRND activities on 3′ non-encoded tail characteristics and mRNA stability in Trypanosoma brucei

Zimmer, S. L., McEvoy, S. M., Menon, S. & Read, L. K., May 21 2012, In : PloS one. 7, 5, e37639.

Research output: Contribution to journalArticle

9 Scopus citations

Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei

Kafková, L., Ammerman, M. L., Faktorová, D., Fisk, J. C., Zimmer, S. L., Sobotka, R., Read, L. K., Lukeš, J. & Hashimi, H., Oct 1 2012, In : RNA. 18, 10, p. 1846-1861 16 p.

Research output: Contribution to journalArticle

33 Scopus citations
2011

A novel member of the RNase D exoribonuclease family functions in mitochondrial guide RNA metabolism in Trypanosoma brucei

Zimmer, S. L., McEvoy, S. M., Li, J., Qu, J. & Read, L. K., Mar 25 2011, In : Journal of Biological Chemistry. 286, 12, p. 10329-10340 12 p.

Research output: Contribution to journalArticle

16 Scopus citations
2009

Polyadenylation in Arabidopsis and Chlamydomonas organelles: The input of nucleotidyltransferases, poly(A) polymerases and polynucleotide phosphorylase

Zimmer, S. L., Schein, A., Zipor, G., Stern, D. B. & Schuster, G., Jul 2009, In : Plant Journal. 59, 1, p. 88-99 12 p.

Research output: Contribution to journalArticle

35 Scopus citations
2008

Genome-based analysis of Chlamydomonas reinhardtii exoribonucleases and poly(A) polymerases predicts unexpected organellar and exosomal features

Zimmer, S. L., Fei, Z. & Stern, D. B., May 1 2008, In : Genetics. 179, 1, p. 125-136 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
2007

Integration of chloroplast nucleic acid metabolism into the phosphate deprivation response in Chlamydomonas reinhardtii

Yehudai-Resheff, S., Zimmer, S. L., Komine, Y. & Stern, D. B., Mar 1 2007, In : Plant Cell. 19, 3, p. 1023-1038 16 p.

Research output: Contribution to journalArticle

57 Scopus citations

The Chlamydomonas genome reveals the evolution of key animal and plant functions

Merchant, S. S., Prochnik, S. E., Vallon, O., Harris, E. H., Karpowicz, S. J., Witman, G. B., Terry, A., Salamov, A., Fritz-Laylin, L. K., Maréchal-Drouard, L., Marshall, W. F., Qu, L. H., Nelson, D. R., Sanderfoot, A. A., Spalding, M. H., Kapitonov, V. V., Ren, Q., Ferris, P., Lindquist, E., Shapiro, H. & 97 others, Lucas, S. M., Grimwood, J., Schmutz, J., Grigoriev, I. V., Rokhsar, D. S., Grossman, A. R., Cardol, P., Cerutti, H., Chanfreau, G., Chen, C. L., Cognat, V., Croft, M. T., Dent, R., Dutcher, S., Fernández, E., Fukuzawa, H., González-Ballester, D., González-Halphen, D., Hallmann, A., Hanikenne, M., Hippler, M., Inwood, W., Jabbari, K., Kalanon, M., Kuras, R., Lefebvre, P. A., Lemaire, S. D., Lobanov, A. V., Lohr, M., Manuell, A., Meier, I., Mets, L., Mittag, M., Mittelmeier, T., Moroney, J. V., Moseley, J., Napoli, C., Nedelcu, A. M., Niyogi, K., Novoselov, S. V., Paulsen, I. T., Pazour, G., Purton, S., Ral, J. P., Riaño-Pachón, D. M., Riekhof, W., Rymarquis, L., Schroda, M., Stern, D., Umen, J., Willows, R., Wilson, N., Zimmer, S. L., Allmer, J., Balk, J., Bisova, K., Chen, C. J., Elias, M., Gendler, K., Hauser, C., Lamb, M. R., Ledford, H., Long, J. C., Minagawa, J., Page, M. D., Pan, J., Pootakham, W., Roje, S., Rose, A., Stahlberg, E., Terauchi, A. M., Yang, P., Ball, S., Bowler, C., Dieckmann, C. L., Gladyshev, V. N., Green, P., Jorgensen, R., Mayfield, S., Mueller-Roeber, B., Rajamani, S., Sayre, R. T., Brokstein, P., Dubchak, I., Goodstein, D., Hornick, L., Huang, Y. W., Jhaveri, J., Luo, Y., Martínez, D., Ngau, W. C. A., Otillar, B., Poliakov, A., Porter, A., Szajkowski, L., Werner, G. & Zhou, K., Oct 12 2007, In : Science. 318, 5848, p. 245-251 7 p.

Research output: Contribution to journalArticle

1594 Scopus citations
2004

Antibiotic-inducible promoter regulated by the cell envelope stress-sensing two-component system LiaRS of Bacillus subtilis

Mascher, T., Zimmer, S. L., Smith, T. A. & Helmann, J. D., Aug 1 2004, In : Antimicrobial agents and chemotherapy. 48, 8, p. 2888-2896 9 p.

Research output: Contribution to journalArticle

165 Scopus citations

Antisense transcript and RNA processing alterations suppress instability of polyadenylated mRNA in chlamydomonas chloroplasts

Nishimura, Y., Kikis, E. A., Zimmer, S. L., Komine, Y. & Stem, D. B., Nov 1 2004, In : Plant Cell. 16, 11, p. 2849-2869 21 p.

Research output: Contribution to journalArticle

39 Scopus citations
2001

Expression of the melanocortin 5 receptor on rat lymphocytes

Akbulut, S., Byersdorfer, C. A., Larsen, C. P., Zimmer, S. L., Humphreys, T. D. & Clarke, B. L., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 281, 5, p. 1086-1092 7 p.

Research output: Contribution to journalArticle

19 Scopus citations