Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
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Projects
- 1 Active
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Minnesota Tissue Mapping Center of Cellular Senescence
Niedernhofer, L. J. (PI), Adeyi, O. (CoI), Aliferis, MD, PhD, C. (CoI), Ikramuddin, S. (CoI), Johnson, S. (CoI), Nelson, A. C. (CoI), Robbins, P. D. (CoI), Wang, J. (CoI) & Mcgowan, S. J. (Other Role)
NIH NATIONAL INSTITUTE ON AGING
9/30/21 → 8/31/26
Project: Research project
Research output
- 18 Article
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Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy
Henpita, C., Vyas, R., Healy, C. L., Kieu, T. L., Gurkar, A. U., Yousefzadeh, M., Cui, Y., Lu, A., Angelini, L., O'Kelly, R., Mcgowan, S. J., Chandrasekhar, S., Vanderpool, R. R., Hennessy-Wack, D., Ross, M. A., Bachman, T. N., McTiernan, C., Pillai, S. P. S., Ladiges, W. & Lavasani, M. & 10 others, , Apr 2023, In: Aging cell. 22, 4, e13782.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
An aged immune system drives senescence and ageing of solid organs
Yousefzadeh, M., Flores, R. R., Zhu, Y., Schmiechen, Z. C., Brooks, R. W., Trussoni, C. E., Cui, Y., Angelini, L., Lee, K. A., Mcgowan, S. J., Burrack, A. L., Wang, D., Dong, Q., Lu, A., Sano, T., O’Kelly, R. D., McGuckian, C. A., Kato, J. I., Bank, M. P. & Wade, E. A. & 13 others, , Jun 2021, In: Nature. 594, 7861, p. 100-105 6 p.Research output: Contribution to journal › Article › peer-review
669 Scopus citations -
Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1 mice
Huerta Guevara, A. P., McGowan, S. J., Kazantzis, M., Stallons, T. R., Sano, T., Mulder, N. L., Jurdzinski, A., van Dijk, T. H., Eggen, B. J. L., Jonker, J. W., Niedernhofer, L. J. & Kruit, J. K., Apr 1 2021, In: Metabolism: clinical and experimental. 117, 154711.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging
Dorronsoro, A., Santiago, F. E., Grassi, D., Zhang, T., Lai, R. C., McGowan, S. J., Angelini, L., Lavasani, M., Corbo, L., Lu, A., Brooks, R. W., Garcia-Contreras, M., Stolz, D. B., Amelio, A., Boregowda, S. V., Fallahi, M., Reich, A., Ricordi, C., Phinney, D. G. & Huard, J. & 3 others, , Apr 2021, In: Aging cell. 20, 4, e13337.Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging
Zhang, L., Zhao, J., Mu, X., McGowan, S. J., Angelini, L., O'Kelly, R. D., Yousefzadeh, M. J., Sakamoto, A., Aversa, Z., LeBrasseur, N. K., Suh, Y., Huard, J., Kamenecka, T. M., Niedernhofer, L. J. & Robbins, P. D., Dec 2021, In: Aging cell. 20, 12, p. e13486 e13486.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations