Sanaz Sedaghat

20132021

Research activity per year

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Search results

  • 1000 Genomes-based metaanalysis identifies 10 novel loci for kidney function

    Gorski, M., Van Der Most, P. J., Teumer, A., Chu, A. Y., Li, M., Mijatovic, V., Nolte, I. M., Cocca, M., Taliun, D., Gomez, F., Li, Y., Tayo, B., Tin, A., Feitosa, M. F., Aspelund, T., Attia, J., Biffar, R., Bochud, M., Boerwinkle, E., Borecki, I. & 106 others, Bottinger, E. P., Chen, M. H., Chouraki, V., Ciullo, M., Coresh, J., Cornelis, M. C., Curhan, G. C., D'Adamo, A. P., Dehghan, A., Dengler, L., Ding, J., Eiriksdottir, G., Endlich, K., Enroth, S., Esko, T., Franco, O. H., Gasparini, P., Gieger, C., Girotto, G., Gottesman, O., Gudnason, V., Gyllensten, U., Hancock, S. J., Harris, T. B., Helmer, C., Höllerer, S., Hofer, E., Hofman, A., Holliday, E. G., Homuth, G., Hu, F. B., Huth, C., Hutri-Kähönen, N., Hwang, S. J., Imboden, M., Johansson, A., Kähönen, M., König, W., Kramer, H., Krämer, B. K., Kumar, A., Kutalik, Z., Lambert, J. C., Launer, L. J., Lehtimäki, T., De Borst, M. H., Navis, G., Swertz, M., Liu, Y., Lohman, K., Loos, R. J. F., Lu, Y., Lyytikäinen, L. P., McEvoy, M. A., Meisinger, C., Meitinger, T., Metspalu, A., Metzger, M., Mihailov, E., Mitchell, P., Nauck, M., Oldehinkel, A. J., Olden, M., Penninx, B. W. J. H., Pistis, G., Pramstaller, P. P., Probst-Hensch, N., Raitakari, O. T., Rettig, R., Ridker, P. M., Rivadeneira, F., Robino, A., Rosas, S. E., Ruderfer, D., Ruggiero, D., Saba, Y., Sala, C., Schmidt, H., Schmidt, R., Scott, R. J., Sedaghat, S., Smith, A. V., Sorice, R., Stengel, B., Stracke, S., Strauch, K., Toniolo, D., Uitterlinden, A. G., Ulivi, S., Viikari, J. S., Völker, U., Vollenweider, P., Völzke, H., Vuckovic, D., Waldenberger, M., Wang, J. J., Yang, Q., Chasman, D. I., Tromp, G., Snieder, H., Heid, I. M., Fox, C. S., Köttgen, A., Pattaro, C., Böger, C. A. & Fuchsberger, C., 2017, In: Scientific reports. 7, 45040.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    51 Scopus citations
  • A catalog of genetic loci associated with kidney function from analyses of a million individuals

    Lifelines Cohort Study & V. A. Million Veteran Program, Jun 1 2019, In: Nature Genetics. 51, 6, p. 957-972 16 p.

    Research output: Contribution to journalArticlepeer-review

    101 Scopus citations
  • A novel inflammatory marker for incident coronary heart disease

    Ligthart, S., Sedaghat, S., Arfan Ikram, M., Hofman, A., Franco, O. H. & Dehghan, A., Dec 11 2014, In: Arteriosclerosis, thrombosis, and vascular biology. 34, 12, p. 2695-2699 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    37 Scopus citations
  • Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies

    Ding, J., Davis-Plourde, K. L., Sedaghat, S., Tully, P. J., Wang, W., Phillips, C., Pase, M. P., Himali, J. J., Gwen Windham, B., Griswold, M., Gottesman, R., Mosley, T. H., White, L., Guðnason, V., Debette, S., Beiser, A. S., Seshadri, S., Ikram, M. A., Meirelles, O., Tzourio, C. & 1 others, Launer, L. J., Jan 2020, In: The Lancet Neurology. 19, 1, p. 61-70 10 p.

    Research output: Contribution to journalArticlepeer-review

    33 Scopus citations
  • Arterial stiffness and decline in kidney function

    Sedaghat, S., Mattace-Raso, F. U. S., Hoorn, E. J., Uitterlinden, A. G., Hofman, A., Ikram, M. A., Franco, O. H. & Dehghan, A., Dec 7 2015, In: Clinical Journal of the American Society of Nephrology. 10, 12, p. 2190-2197 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    62 Scopus citations
  • Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer’s disease: Pooled analysis from 5 cohorts

    Weinstein, G., Davis-Plourde, K. L., Conner, S., Himali, J. J., Beiser, A. S., Lee, A., Rawlings, A. M., Sedaghat, S., Ding, J., Moshier, E., Van Duijn, C. M., Beeri, M. S., Selvin, E., Arfan Ikram, M., Launer, L. J., Haan, M. N. & Seshadri, S., Feb 2019, In: PloS one. 14, 2, e0212293.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Association of renal function with vascular stiffness in older adults: the Rotterdam study

    Sedaghat, S., Dawkins Arce, F. G., Verwoert, G. C., Hofman, A., Ikram, M. ARFAN., Franco, OSCAR. H., Dehghan, A., Witteman, J. C. M. & Mattace-Raso, F., Nov 1 2014, In: Age and Ageing. 43, 6, p. 827-833 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    10 Scopus citations
  • Association of uric acid genetic risk score with blood pressure: The rotterdam study

    Sedaghat, S., Pazoki, R., Uitterlinden, A. G., Hofman, A., Stricker, B. H. C., Ikram, M. A., Franco, O. H. & Dehghan, A., Nov 1 2014, In: Hypertension. 64, 5, p. 1061-1066 6 p.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Carotid Stiffness Is Associated with Incident Stroke A Systematic Review and Individual Participant Data Meta-Analysis

    Van Sloten, T. T., Sedaghat, S., Laurent, S., London, G. M., Pannier, B., Ikram, M. A., Kavousi, M., Mattace-Raso, F., Franco, O. H., Boutouyrie, P. & Stehouwer, C. D. A., 2015, In: Journal of the American College of Cardiology. 66, 19, p. 2116-2125 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    95 Scopus citations
  • Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression

    van Sloten, T. T., Sedaghat, S., Carnethon, M. R., Launer, L. J. & Stehouwer, C. D. A., Apr 2020, In: The Lancet Diabetes and Endocrinology. 8, 4, p. 325-336 12 p.

    Research output: Contribution to journalReview articlepeer-review

    21 Scopus citations
  • Common carotid artery diameter and risk of cardiovascular events and mortality: Pooled analyses of four cohort studies

    Sedaghat, S., Van Sloten, T. T., Laurent, S., London, G. M., Pannier, B., Kavousi, M., Mattace-Raso, F., Franco, O. H., Boutouyrie, P., Ikram, M. A. & Stehouwer, C. D. A., Jul 1 2018, In: Hypertension. 72, 1, p. 85-92 8 p.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Coronary heart disease, heart failure, and the risk of dementia: A systematic review and meta-analysis

    Wolters, F. J., Segufa, R. A., Darweesh, S. K. L., Bos, D., Ikram, M. A., Sabayan, B., Hofman, A. & Sedaghat, S., Nov 2018, In: Alzheimer's and Dementia. 14, 11, p. 1493-1504 12 p.

    Research output: Contribution to journalReview articlepeer-review

    41 Scopus citations
  • Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

    Gorski, M., Most, P. J. V. D., Teumer, A., Chu, A. Y., Li, M., Mijatovic, V., Nolte, I. M., Cocca, M., Taliun, D., Gomez, F., Li, Y., Tayo, B., Tin, A., Feitosa, M. F., Aspelund, T., Attia, J., Biffar, R., Bochud, M., Boerwinkle, E., Borecki, I. & 106 others, Bottinger, E. P., Chen, M. H., Chouraki, V., Ciullo, M., Coresh, J., Cornelis, M. C., Curhan, G. C., Adamo, A. P. D., Dehghan, A., Dengler, L., Ding, J., Eiriksdottir, G., Endlich, K., Enroth, S., Esko, T., Franco, O. H., Gasparini, P., Gieger, C., Girotto, G., Gottesman, O., Gudnason, V., Gyllensten, U., Hancock, S. J., Harris, T. B., Helmer, C., Höllerer, S., Hofer, E., Hofman, A., Holliday, E. G., Homuth, G., Hu, F. B., Huth, C., Hutri-Kähönen, N., Hwang, S. J., Imboden, M., Johansson, Å., Kähönen, M., König, W., Kramer, H., Krämer, B. K., Kumar, A., Kutalik, Z., Lambert, J. C., Launer, L. J., Lehtimäki, T., de Borst, M. H., Navis, G., Swertz, M., Liu, Y., Lohman, K., Loos, R. J. F., Lu, Y., Lyytikäinen, L. P., McEvoy, M. A., Meisinger, C., Meitinger, T., Metspalu, A., Metzger, M., Mihailov, E., Mitchell, P., Nauck, M., Oldehinkel, A. J., Olden, M., Wjh Penninx, B., Pistis, G., Pramstaller, P. P., Probst-Hensch, N., Raitakari, O. T., Rettig, R., Ridker, P. M., Rivadeneira, F., Robino, A., Rosas, S. E., Ruderfer, D., Ruggiero, D., Saba, Y., Sala, C., Schmidt, H., Schmidt, R., Scott, R. J., Sedaghat, S., Smith, A. V., Sorice, R., Stengel, B., Stracke, S., Strauch, K., Toniolo, D., Uitterlinden, A. G., Ulivi, S., Viikari, J. S., Völker, U., Vollenweider, P., Völzke, H., Vuckovic, D., Waldenberger, M., Wang, J. J., Yang, Q., Chasman, D. I., Tromp, G., Snieder, H., Heid, I. M., Fox, C. S., Köttgen, A., Pattaro, C., Böger, C. A. & Fuchsberger, C., May 26 2017, In: Scientific reports. 7, p. 46835 1 p., 46835.

    Research output: Contribution to journalComment/debatepeer-review

    Open Access
  • Cumulative blood pressure exposure, basal ganglia, and thalamic morphology in midlife

    Jenkins, L. M., Garner, C. R., Kurian, S., Higgins, J. P., Parrish, T. B., Sedaghat, S., Nemeth, A. J., Lloyd-Jones, D. M., Launer, L. J., Hausdorff, J. M., Wang, L. & Sorond, F. A., May 2020, In: Hypertension. p. 1289-1295 7 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Cumulative blood pressure exposure during young adulthood and mobility and cognitive function in midlife

    Mahinrad, S., Kurian, S., Garner, C. R., Sedaghat, S., Nemeth, A. J., Moscufo, N., Higgins, J. P., Jacobs, D. R., Hausdorff, J. M., Lloyd-Jones, D. M. & Sorond, F. A., Mar 3 2020, In: Circulation. p. 712-724 13 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

    van der Laan, S. W., Fall, T., Soumaré, A., Teumer, A., Sedaghat, S., Baumert, J., Zabaneh, D., van Setten, J., Isgum, I., Galesloot, T. E., Arpegård, J., Amouyel, P., Trompet, S., Waldenberger, M., Dörr, M., Magnusson, P. K., Giedraitis, V., Larsson, A., Morris, A. P., Felix, J. F. & 52 others, Morrison, A. C., Franceschini, N., Bis, J. C., Kavousi, M., O'Donnell, C., Drenos, F., Tragante, V., Munroe, P. B., Malik, R., Dichgans, M., Worrall, B. B., Erdmann, J., Nelson, C. P., Samani, N. J., Schunkert, H., Marchini, J., Patel, R. S., Hingorani, A. D., Lind, L., Pedersen, N. L., de Graaf, J., Kiemeney, L. A. L. M., Baumeister, S. E., Franco, O. H., Hofman, A., Uitterlinden, A. G., Koenig, W., Meisinger, C., Peters, A., Thorand, B., Jukema, J. W., Eriksen, B. O., Toft, I., Wilsgaard, T., Onland-Moret, N. C., van der Schouw, Y. T., Debette, S., Kumari, M., Svensson, P., van der Harst, P., Kivimaki, M., Keating, B. J., Sattar, N., Dehghan, A., Reiner, A. P., Ingelsson, E., den Ruijter, H. M., de Bakker, P. I. W., Pasterkamp, G., Ärnlöv, J., Holmes, M. V. & Asselbergs, F. W., Aug 30 2016, In: Journal of the American College of Cardiology. 68, 9, p. 934-945 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    38 Scopus citations
  • Decline in kidney function over the course of adulthood and cognitive function in midlife

    Sedaghat, S., Sorond, F., Yaffe, K., Sidney, S., Kramer, H. J., Jacobs, D. R., Launer, L. J. & Carnethon, M. R., Oct 27 2020, In: Neurology. 95, 17, p. e2389-e2397

    Research output: Contribution to journalArticlepeer-review

  • Development of a Healthy Aging Score in the Population-Based Rotterdam Study: Evaluating Age and Sex Differences

    Jaspers, L., Schoufour, J. D., Erler, N. S., Darweesh, S. K. L., Portegies, M. L. P., Sedaghat, S., Lahousse, L., Brusselle, G. G., Stricker, B. H., Tiemeier, H., Ikram, M. A., Laven, J. S. E., Franco, O. H. & Kavousi, M., Mar 1 2017, In: Journal of the American Medical Directors Association. 18, 3, p. 276.e1-276.e7

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Effect of metabolic genetic variants on long-term disease comorbidity in patients with type 2 diabetes

    Abedian, S., Abbasi, A., de Boer, A., Stricker, B. H., Bakker, S. J. L., van der Harst, P., Sedaghat, S., Darvishian, M., Ikram, M. A., Navis, G., Dehghan, A., Pen, I., Stolk, R. P., Snieder, H., Klungel, O. H., Souverein, P. & Alizadeh, B. Z., Feb 2 2021, In: Scientific reports. 11, 1, 2794.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Effects of lifestyle-related interventions on blood pressure in low and middle-income countries: Systematic review and meta-analysis

    Baena, C. P., Olandoski, M., Younge, J. O., Buitrago-Lopez, A., Darweesh, S. K. L., Campos, N., Sedaghat, S., Sajjad, A., Van Herpt, T. T. W., Freak-Poli, R., Van Den Hooven, E., Felix, J. F., Faria-Neto, J. R., Chowdhury, R. & Franco, O. H., May 2014, In: Journal of hypertension. 32, 5, p. 961-973 13 p.

    Research output: Contribution to journalReview articlepeer-review

    23 Scopus citations
  • Effects of protein intake on blood pressure, insulin sensitivity and blood lipids in children: A systematic review

    Voortman, T., Vitezova, A., Bramer, W. M., Ars, C. L., Bautista, P. K., Buitrago-Lopez, A., Felix, J. F., Leermakers, E. T. M., Sajjad, A., Sedaghat, S., Tharner, A., Franco, O. H. & Van Den Hooven, E. H., Feb 14 2015, In: British Journal of Nutrition. 113, 3, p. 383-402 20 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    9 Scopus citations
  • Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

    Teumer, A., Li, Y., Ghasemi, S., Prins, B. P., Wuttke, M., Hermle, T., Giri, A., Sieber, K. B., Qiu, C., Kirsten, H., Tin, A., Chu, A. Y., Bansal, N., Feitosa, M. F., Wang, L., Chai, J. F., Cocca, M., Fuchsberger, C., Gorski, M., Hoppmann, A. & 166 others, Horn, K., Li, M., Marten, J., Noce, D., Nutile, T., Sedaghat, S., Sveinbjornsson, G., Tayo, B. O., van der Most, P. J., Xu, Y., Yu, Z., Gerstner, L., Ärnlöv, J., Bakker, S. J. L., Baptista, D., Biggs, M. L., Boerwinkle, E., Brenner, H., Burkhardt, R., Carroll, R. J., Chee, M. L., Chee, M. L., Chen, M., Cheng, C. Y., Cook, J. P., Coresh, J., Corre, T., Danesh, J., de Borst, M. H., De Grandi, A., de Mutsert, R., de Vries, A. P. J., Degenhardt, F., Dittrich, K., Divers, J., Eckardt, K. U., Ehret, G., Endlich, K., Felix, J. F., Franco, O. H., Franke, A., Freedman, B. I., Freitag-Wolf, S., Gansevoort, R. T., Giedraitis, V., Gögele, M., Grundner-Culemann, F., Gudbjartsson, D. F., Gudnason, V., Hamet, P., Harris, T. B., Hicks, A. A., Holm, H., Foo, V. H. X., Hwang, S. J., Ikram, M. A., Ingelsson, E., Jaddoe, V. W. V., Jakobsdottir, J., Josyula, N. S., Jung, B., Kähönen, M., Khor, C. C., Kiess, W., Koenig, W., Körner, A., Kovacs, P., Kramer, H., Krämer, B. K., Kronenberg, F., Lange, L. A., Langefeld, C. D., Lee, J. J. M., Lehtimäki, T., Lieb, W., Lim, S. C., Lind, L., Lindgren, C. M., Liu, J., Loeffler, M., Lyytikäinen, L. P., Mahajan, A., Maranville, J. C., Mascalzoni, D., McMullen, B., Meisinger, C., Meitinger, T., Miliku, K., Mook-Kanamori, D. O., Müller-Nurasyid, M., Mychaleckyj, J. C., Nauck, M., Nikus, K., Ning, B., Noordam, R., Connell, J. O., Olafsson, I., Palmer, N. D., Peters, A., Podgornaia, A. I., Ponte, B., Poulain, T., Pramstaller, P. P., Rabelink, T. J., Raffield, L. M., Reilly, D. F., Rettig, R., Rheinberger, M., Rice, K. M., Rivadeneira, F., Runz, H., Ryan, K. A., Sabanayagam, C., Saum, K. U., Schöttker, B., Shaffer, C. M., Shi, Y., Smith, A. V., Strauch, K., Stumvoll, M., Sun, B. B., Szymczak, S., Tai, E. S., Tan, N. Y. Q., Taylor, K. D., Teren, A., Tham, Y. C., Thiery, J., Thio, C. H. L., Thomsen, H., Thorsteinsdottir, U., Tönjes, A., Tremblay, J., Uitterlinden, A. G., van der Harst, P., Verweij, N., Vogelezang, S., Völker, U., Waldenberger, M., Wang, C., Wilson, O. D., Wong, C., Wong, T. Y., Yang, Q., Yasuda, M., Akilesh, S., Bochud, M., Böger, C. A., Devuyst, O., Edwards, T. L., Ho, K., Morris, A. P., Parsa, A., Pendergrass, S. A., Psaty, B. M., Rotter, J. I., Stefansson, K., Wilson, J. G., Susztak, K., Snieder, H., Heid, I. M., Scholz, M., Butterworth, A. S., Hung, A. M., Pattaro, C. & Köttgen, A., Dec 1 2019, In: Nature communications. 10, 1, 4130.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Genome-wide association study of kidney function decline in individuals of European descent

    Gorski, M., Tin, A., Garnaas, M., McMahon, G. M., Chu, A. Y., Tayo, B. O., Pattaro, C., Teumer, A., Chasman, D. I., Chalmers, J., Hamet, P., Tremblay, J., Woodward, M., Aspelund, T., Eiriksdottir, G., Gudnason, V., Harris, T. B., Launer, L. J., Smith, A. V., Mitchell, B. D. & 84 others, O'Connell, J. R., Shuldiner, A. R., Coresh, J., Li, M., Freudenberger, P., Hofer, E., Schmidt, H., Schmidt, R., Holliday, E. G., Mitchell, P., Wang, J. J., De Boer, I. H., Li, G., Siscovick, D. S., Kutalik, Z., Corre, T., Vollenweider, P., Waeber, G., Gupta, J., Kanetsky, P. A., Hwang, S. J., Olden, M., Yang, Q., De Andrade, M., Atkinson, E. J., Kardia, S. L. R., Turner, S. T., Stafford, J. M., Ding, J., Liu, Y., Barlassina, C., Cusi, D., Salvi, E., Staessen, J. A., Ridker, P. M., Grallert, H., Meisinger, C., Müller-Nurasyid, M., Krämer, B. K., Kramer, H., Rosas, S. E., Nolte, I. M., Penninx, B. W., Snieder, H., Fabiola Del Greco, M., Franke, A., Nöthlings, U., Lieb, W., Bakker, S. J. L., Gansevoort, R. T., Van Der Harst, P., Dehghan, A., Franco, O. H., Hofman, A., Rivadeneira, F., Sedaghat, S., Uitterlinden, A. G., Coassin, S., Haun, M., Kollerits, B., Kronenberg, F., Paulweber, B., Aumann, N., Endlich, K., Pietzner, M., Völker, U., Rettig, R., Chouraki, V., Helmer, C., Lambert, J. C., Metzger, M., Stengel, B., Lehtimäki, T., Lyytikäinen, L. P., Raitakari, O., Johnson, A., Parsa, A., Bochud, M., Heid, I. M., Goessling, W., Köttgen, A., Kao, W. H. L., Fox, C. S. & Böger, C. A., May 11 2015, In: Kidney international. 87, 5, p. 1017-1029 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    75 Scopus citations
  • Kidney function, gait pattern and fall in the general population: A cohort study

    Sedaghat, S., Darweesh, S. K. L., Verlinden, V. J. A., Van Der Geest, J. N., Dehghan, A., Franco, O. H., Hoorn, E. J. & Ikram, M. A., Dec 1 2018, In: Nephrology Dialysis Transplantation. 33, 12, p. 2165-2172 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Kidney Function and Arterial Calcification in Major Vascular Beds

    Sedaghat, S., Hoorn, E. J., Ikram, M. A., Koop-Nieuwelink, C., Kavousi, M., Franco, O. H., van der Lugt, A., Vernooij, M. W. & Bos, D., May 7 2019, In: Journal of the American Heart Association. 8, 9, e010930.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Kidney function and cerebral blood flow: The Rotterdam study

    Sedaghat, S., Vernooij, M. W., Loehrer, E., Mattace-Raso, F. U. S., Hofman, A., Van Der Lugt, A., Franco, O. H., Dehghan, A. & Ikram, M. A., Mar 2016, In: Journal of the American Society of Nephrology. 27, 3, p. 715-721 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • Kidney function and cerebral small vessel disease in the general population

    Akoudad, S., Sedaghat, S., Hofman, A., Koudstaal, P. J., van der Lugt, A., Ikram, M. A. & Vernooij, M. W., Jun 1 2015, In: International Journal of Stroke. 10, 4, p. 603-608 6 p.

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations
  • Kidney function and microstructural integrity of brain white matter

    Sedaghat, S., Cremers, L. G. M., De Groot, M., Hoorn, E. J., Hofman, A., Van Der Lugt, A., Franco, O. H., Vernooij, M. W., Dehghan, A. & Ikram, M. A., Jul 1 2015, In: Neurology. 85, 2, p. 154-161 8 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Kidney Function and the Risk of Stroke and Dementia: The Rotterdam Study

    Koop-Nieuwelink, C., Sedaghat, S., Mutlu, U., Licher, S., Franco, O. H., Ikram, M. A., Geerlings, M. I., Ikram, M. K. & Bos, D., 2019, In: Journal of Alzheimer's Disease. 67, 3, p. 821-826 6 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

    Tin, A., Li, Y., Brody, J. A., Nutile, T., Chu, A. Y., Huffman, J. E., Yang, Q., Chen, M. H., Robinson-Cohen, C., Macé, A., Liu, J., Demirkan, A., Sorice, R., Sedaghat, S., Swen, M., Yu, B., Ghasemi, S., Teumer, A., Vollenweider, P., Ciullo, M. & 15 others, Li, M., Uitterlinden, A. G., Kraaij, R., Amin, N., van Rooij, J., Kutalik, Z., Dehghan, A., McKnight, B., van Duijn, C. M., Morrison, A., Psaty, B. M., Boerwinkle, E., Fox, C. S., Woodward, O. M. & Köttgen, A., Dec 1 2018, In: Nature communications. 9, 1, 4228.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • LDL cholesterol still a problem in old age? A Mendelian randomization study

    Postmus, I., Deelen, J., Sedaghat, S., Trompet, S., De Craen, A. J. M., Heijmans, B. T., Franco, O. H., Hofman, A., Dehghan, A., Slagboom, P. E., Westendorp, R. G. J. & Jukema, J. W., May 27 2015, In: International journal of epidemiology. 44, 2, p. 604-612 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

    Saleheen, D., Zhao, W., Young, R., Nelson, C. P., Ho, W., Ferguson, J. F., Rasheed, A., Ou, K., Nurnberg, S. T., Bauer, R. C., Goel, A., Do, R., Stewart, A. F. R., Hartiala, J., Zhang, W., Thorleifsson, G., Strawbridge, R. J., Sinisalo, J., Kanoni, S., Sedaghat, S. & 50 others, Marouli, E., Kristiansson, K., Zhao, J. H., Scott, R., Gauguier, D., Shah, S. H., Smith, A. V., Van Zuydam, N., Cox, A. J., Willenborg, C., Kessler, T., Zeng, L., Province, M. A., Ganna, A., Lind, L., Pedersen, N. L., White, C. C., Joensuu, A., Kleber, M. E., Hall, A. S., März, W., Salomaa, V., O'Donnell, C., Ingelsson, E., Feitosa, M. F., Erdmann, J., Bowden, D. W., Palmer, C. N. A., Gudnason, V., Faire, U. D., Zalloua, P., Wareham, N., Thompson, J. R., Kuulasmaa, K., Dedoussis, G., Perola, M., Dehghan, A., Chambers, J. C., Kooner, J., Allayee, H., Deloukas, P., McPherson, R., Stefansson, K., Schunkert, H., Kathiresan, S., Farrall, M., Marcel Frossard, P., Rader, D. J., Samani, N. J. & Reilly, M. P., Jun 13 2017, In: Circulation. 135, 24, p. 2336-2353 18 p.

    Research output: Contribution to journalArticlepeer-review

    20 Scopus citations
  • Lower microstructural integrity of brain white matter is related to higher mortality

    Sedaghat, S., Cremers, L. G. M., De Groot, M., Hofman, A., Van Der Lugt, A., Niessen, W. J., Franco, O. H., Dehghan, A., Ikram, M. A. & Vernooij, M. W., Aug 30 2016, In: Neurology. 87, 9, p. 927-934 8 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

    Lifelines Cohort Study & Regeneron Genetics Center, Apr 1 2021, In: Kidney international. 99, 4, p. 926-939 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Plasma tau, neurofilament light chain and amyloid-b levels and risk of dementia; a population-based cohort study

    de Wolf, F., Ghanbari, M., Licher, S., McRae-McKee, K., Gras, L., Weverling, G. J., Wermeling, P., Sedaghat, S., Kamran Ikram, M., Waziry, R., Koudstaal, W., Klap, J., Kostense, S., Hofman, A., Anderson, R., Goudsmit, J. & Arfan Ikram, M., Mar 1 2020, In: Brain. 143, 3, p. 1220-1232 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • Protein intake in infancy and kidney size and function at the age of 6 years: The Generation R Study

    Voortman, T., Bakker, H., Sedaghat, S., Kiefte–de Jong, J. C., Hofman, A., Jaddoe, V. W. V., Franco, O. H. & van den Hooven, E. H., Oct 28 2015, In: Pediatric Nephrology. 30, 10, p. 1825-1833 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Quantification of biological age as a determinant of age-related diseases in the Rotterdam Study: a structural equation modeling approach

    Waziry, R., Gras, L., Sedaghat, S., Tiemeier, H., Weverling, G. J., Ghanbari, M., Klap, J., de Wolf, F., Hofman, A., Ikram, M. A. & Goudsmit, J., Aug 15 2019, In: European Journal of Epidemiology. 34, 8, p. 793-799 7 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium

    CKD Prognosis Consortium, Feb 1 2019, In: American Journal of Kidney Diseases. 73, 2, p. 206-217 12 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Serum uric acid and chronic kidney disease: The role of hypertension

    Sedaghat, S., Hoorn, E. J., Van Rooij, F. J. A., Hofman, A., Franco, O. H., Witteman, J. C. M. & Dehghan, A., Nov 12 2013, In: PloS one. 8, 11, e76827.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    43 Scopus citations
  • SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

    Li, M., Li, Y., Weeks, O., Mijatovic, V., Teumer, A., Huffman, J. E., Tromp, G., Fuchsberger, C., Gorski, M., Lyytikäinen, L. P., Nutile, T., Sedaghat, S., Sorice, R., Tin, A., Yang, Q., Ahluwalia, T. S., Arking, D. E., Bihlmeyer, N. A., Böger, C. A., Carroll, R. J. & 136 others, Chasman, D. I., Cornelis, M. C., Dehghan, A., Faul, J. D., Feitosa, M. F., Gambaro, G., Gasparini, P., Giulianini, F., Heid, I., Huang, J., Imboden, M., Jackson, A. U., Jeff, J., Jhun, M. A., Katz, R., Kifley, A., Kilpeläinen, T. O., Kumar, A., Laakso, M., Li-Gao, R., Lohman, K., Lu, Y., Mägi, R., Malerba, G., Mihailov, E., Mohlke, K. L., Mook-Kanamori, D. O., Robino, A., Ruderfer, D., Salvi, E., Schick, U. M., Schulz, C. A., Smith, A. V., Smith, J. A., Traglia, M., Yerges-Armstrong, L. M., Zhao, W., Goodarzi, M. O., Kraja, A. T., Liu, C., Wessel, J., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bottinger, E. P., Braga, D., Brandslund, I., Brody, J. A., Campbell, A., Carey, D. J., Christensen, C., Coresh, J., Crook, E., Curhan, G. C., Cusi, D., De Boer, I. H., De Vries, A. P. J., Denny, J. C., Devuyst, O., Dreisbach, A. W., Endlich, K., Esko, T., Franco, O. H., Fulop, T., Gerhard, G. S., Glümer, C., Gottesman, O., Grarup, N., Gudnason, V., Hansen, T., Harris, T. B., Hayward, C., Hocking, L., Hofman, A., Hu, F. B., Husemoen, L. L. N., Jackson, R. D., Jørgensen, T., Jørgensen, M. E., Kähönen, M., Kardia, S. L. R., König, W., Kooperberg, C., Kriebel, J., Launer, L. J., Lauritzen, T., Lehtimäki, T., Levy, D., Linksted, P., Linneberg, A., Liu, Y., Loos, R. J. F., Lupo, A., Meisinger, C., Melander, O., Metspalu, A., Mitchell, P., Nauck, M., Nürnberg, P., Orho-Melander, M., Parsa, A., Pedersen, O., Peters, A., Peters, U., Polasek, O., Porteous, D., Probst-Hensch, N. M., Psaty, B. M., Qi, L., Raitakari, O. T., Reiner, A. P., Rettig, R., Ridker, P. M., Rivadeneira, F., Rossouw, J. E., Schmidt, F., Siscovick, D., Soranzo, N., Strauch, K., Toniolo, D., Turner, S. T., Uitterlinden, A. G., Ulivi, S., Velayutham, D., Völker, U., Völzke, H., Waldenberger, M., Wang, J. J., Weir, D. R., Witte, D., Kuivaniemi, H., Fox, C. S., Franceschini, N., Goessling, W., Köttgen, A. & Chu, A. Y., Mar 2017, In: Journal of the American Society of Nephrology. 28, 3, p. 981-994 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

    German Chronic Kidney Disease Study, Lifelines Cohort Study & V. A. Million Veteran Program, Oct 1 2019, In: Nature Genetics. 51, 10, p. 1459-1474 16 p.

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations
  • Telomere Length and the Risk of Alzheimer's Disease: The Rotterdam Study

    Fani, L., Hilal, S., Sedaghat, S., Broer, L., Licher, S., Arp, P. P., Van Meurs, J. B. J., Ikram, M. K. & Ikram, M. A., 2020, In: Journal of Alzheimer's Disease. 73, 2, p. 707-714 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • The AGES-Reykjavik Study suggests that change in kidney measures is associated with subclinical brain pathology in older community-dwelling persons

    Sedaghat, S., Ding, J., Eiriksdottir, G., van Buchem, M. A., Sigurdsson, S., Ikram, M. A., Meirelles, O., Gudnason, V., Levey, A. S. & Launer, L. J., Sep 2018, In: Kidney international. 94, 3, p. 608-615 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucose

    Ghanbari, M., Sedaghat, S., De Looper, H. W. J., Hofman, A., Erkeland, S. J., Franco, O. H. & Dehghan, A., Feb 1 2015, In: Obesity. 23, 2, p. 495-503 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • The association of thyroid function and the risk of kidney function decline: A population-based cohort study

    Chaker, L., Sedaghat, S., Hoorn, E. J., Den Elzen, W. P. J., Gussekloo, J., Hofman, A., Ikram, M. A., Franco, O. H., Dehghan, A. & Peeters, R. P., Dec 2016, In: European Journal of Endocrinology. 175, 6, p. 653-660 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Vascular health across young adulthood and midlife cerebral autoregulation, gait, and cognition

    Mahinrad, S., Shownkeen, M., Sedaghat, S., Yaffe, K., Hausdorff, J. M., Lloyd-Jones, D. M., Gorelick, P. B. & Sorond, F. A., May 2021, In: Alzheimer's and Dementia. 17, 5, p. 745-754 10 p.

    Research output: Contribution to journalArticlepeer-review

  • von Willebrand Factor, ADAMTS13 Activity, and Decline in Kidney Function: A Population-Based Cohort Study

    Sedaghat, S., de Vries, P. S., Boender, J., Sonneveld, M. A. H., Hoorn, E. J., Hofman, A., de Maat, M. P. M., Franco, O. H., Ikram, M. A., Leebeek, F. W. G. & Dehghan, A., Nov 1 2016, In: American Journal of Kidney Diseases. 68, 5, p. 726-732 7 p.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations