Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 3 Active
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Development of deazaflavin analogs as potent and selective MRP1 inhibitors for cancer chemosensitization
Xie, J. (PI), Wang, Z. (Co-Principal Investigator), Kaur, R. (Other Role) & Offei, S. (Other Role)
9/5/25 → 8/31/27
Project: Research project
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Novel HIV capsid-targeting antivirals maintain activity against lenacapavir-resistant viruses
Wang, Z. (PI) & Offei, S. (Other Role)
EMORY UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
1/17/25 → 12/31/26
Project: Research project
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Development of novel antivirals against mpox (monkeypox) virus
Chen, Y. (PI), Wang, Z. (PI), Xie, J. (CoI), Belhadj, Z. (Other Role), Jagtap, A. (Other Role), Offei, S. (Other Role), Shahari, M. S. B. (Other Role) & gao, Y. (Other Role)
NIH NATIONAL INST OF ALLERGY & INFECT DI
6/14/24 → 4/30/29
Project: Research project
Research output
- 5 Article
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1,4-Dihydroxy-1,8-napthyridinone (DHN) analogs as HIV-1 reverse transcriptase-associated RNase H inhibitors
Shahari, M. S. B., Offei, S., Zhang, H., Prahlad, J., Mahoney, J. P., Kirby, K. A., Sarafianos, S. G. & Wang, Z., Sep 15 2026, In: Bioorganic Chemistry. 180, 110119.Research output: Contribution to journal › Article › peer-review
Open Access -
1-Hydroxy-1,8-napthyridinone (DHN) Analogs Potently Inhibit Monkeypox Virus Resolvase (Mpr)
Offei, S., Mahoney, J. P., Wang, Z., Pant, A., Ryu, W. H., Katekar, R., Xie, J., Yang, Z. & Wang, Z., Jan 8 2026, In: Journal of medicinal chemistry. 69, 1, p. 698-714 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Discovery of Small-Molecule Orthopoxvirus Resolvase Inhibitors with Antiviral Activity
Mahoney, J., Offei, S., Pant, A., Wang, Z., Weiner, B., Yin, L., Ryu, W. H., Katekar, R., Williams, J. M., Aihara, H., Yang, Z. & Wang, Z., Jul 10 2025, In: Journal of medicinal chemistry. 68, 13, p. 13358-13375 18 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations -
Cancer sensitizing effect of deazaflavin analogs is associated with increased intracellular drug accumulation
Belhadj, Z., Offei, S., Jacobson, B. A., Cambron, D., Kratzke, R. A., Wang, Z. & Xie, J., Feb 1 2024, In: European Journal of Pharmaceutical Sciences. 193, 106686.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Antiviral activities of two nucleos(t)ide analogs against vaccinia, mpox, and cowpox viruses in primary human fibroblasts
Dsouza, L., Pant, A., Offei, S., Priyamvada, L., Pope, B., Satheshkumar, P. S., Wang, Z. & Yang, Z., Aug 2023, In: Antiviral Research. 216, 105651.Research output: Contribution to journal › Article › peer-review
Open Access23 Link opens in a new tab Scopus citations