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Research Output 1970 2019

2019
1 Citation (Scopus)

Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy

Yue, W., Tong, L., Liu, X., Weng, X., Chen, X., Wang, D., Dudley, S., Weir, E. K., Ding, W., Lu, Z., Xu, Y. & Chen, Y., Apr 1 2019, In : Redox Biology. 22, 101161.

Research output: Contribution to journalArticle

Open Access
Right Ventricular Hypertrophy
Pneumonia
Heart Failure
Oxidative stress
Constriction
1 Citation (Scopus)

Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL)

Roder, K., Kabakov, A., Moshal, K. S., Murphy, K. R., Xie, A., Dudley, S., Turan, N. N., Lu, Y., MacRae, C. A. & Koren, G., Jan 1 2019, In : Journal of Biological Chemistry. 294, 1, p. 351-360 10 p.

Research output: Contribution to journalArticle

Human Trafficking
Potassium Channels
Ligases
Ubiquitin
Ether
2018
5 Citations (Scopus)

A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality

Zhang, X., Yoon, J. Y., Morley, M., McLendon, J. M., Mapuskar, K. A., Gutmann, R., Mehdi, H., Bloom, H. L., Dudley, S. C., Ellinor, P. T., Shalaby, A. A., Weiss, R., Tang, W. H. W., Moravec, C. S., Singh, M., Taylor, A. L., Yancy, C. W., Feldman, A. M., McNamara, D. M., Irani, K. & 5 othersSpitz, D. R., Breheny, P., Margulies, K. B., London, B. & Boudreau, R. L., Mar 1 2018, In : Journal of Clinical Investigation. 128, 3, p. 1154-1163 10 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Single Nucleotide Polymorphism
Heart Failure
Mortality
Alleles
2 Citations (Scopus)

Activation of the unfolded protein response downregulates cardiac ion channels in human induced pluripotent stem cell-derived cardiomyocytes

Liu, M., Shi, G., Zhou, A., Rupert, C. E., Coulombe, K. L. K. & Dudley, S., Apr 1 2018, In : Journal of Molecular and Cellular Cardiology. 117, p. 62-71 10 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Induced Pluripotent Stem Cells
Ion Channels
Cardiac Myocytes
Down-Regulation

Functional cardiac na+ channels are expressed in human melanoma cells

Xie, A., Gallant, B., Guo, H., Gonzalez, A., Clark, M., Madigan, A., Feng, F., Chen, H. D., Cui, Y., Dudley, S. & Wan, Y., Aug 1 2018, In : Oncology Letters. 16, 2, p. 1689-1695 7 p.

Research output: Contribution to journalArticle

Melanoma
Membrane Potentials
Tetrodotoxin
Action Potentials
Carcinogenesis
2 Citations (Scopus)

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure

Zhou, A., Xie, A., Kim, T. Y., Liu, H., Shi, G., Kang, G-J., Jiang, N., Liu, M., Jeong, E. M., Choi, B. R. & Dudley, S., Jul 1 2018, In : Heart Rhythm. 15, 7, p. 1072-1080 9 p.

Research output: Contribution to journalArticle

Open Access
RNA Stability
Heart Failure
Messenger RNA
Down-Regulation
Cardiac Myocytes
1 Citation (Scopus)

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes

Xie, A., Zhou, A., Liu, H., Shi, G., Liu, M., Boheler, K. R. & Dudley, S., Jul 1 2018, In : PloS one. 13, 7, e0200448.

Research output: Contribution to journalArticle

Stem cells
Ryanodine Receptor Calcium Release Channel
Cardiac Myocytes
Sarcoplasmic Reticulum
Fluxes
3 Citations (Scopus)

Mitochondrial Ca2+ influx contributes to arrhythmic risk in nonischemic cardiomyopathy

Xie, A., Song, Z., Liu, H., Zhou, A., Shi, G., Wang, Q., Gu, L., Liu, M., Xie, L. H., Qu, Z. & Dudley, S., Apr 17 2018, In : Journal of the American Heart Association. 7, 8, e007805.

Research output: Contribution to journalArticle

Cardiomyopathies
Heart Failure
Muscle Cells
Action Potentials
Ventricular Fibrillation
16 Citations (Scopus)

Multi-ethnic genome-wide association study for atrial fibrillation

Roselli, C., Chaffin, M. D., Weng, L. C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A. & 198 othersCalkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y. D. I., Choi, E. K., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Dörr, M., Dudink, E. A., Dudley, S. C., Esa, N., Esko, T., Eskola, M., Fatkin, D., Felix, S. B., Ford, I., Franco, O. H., Geelhoed, B., Grewal, R. P., Gudnason, V., Guo, X., Gupta, N., Gustafsson, S., Gutmann, R., Hamsten, A., Harris, T. B., Hayward, C., Heckbert, S. R., Hernesniemi, J., Hocking, L. J., Hofman, A., Horimoto, A. R. V. R., Huang, J., Huang, P. L., Huffman, J., Ingelsson, E., Ipek, E. G., Ito, K., Jimenez-Conde, J., Johnson, R., Jukema, J. W., Kääb, S., Kähönen, M., Kamatani, Y., Kane, J. P., Kastrati, A., Kathiresan, S., Katschnig-Winter, P., Kavousi, M., Kessler, T., Kietselaer, B. L., Kirchhof, P., Kleber, M. E., Knight, S., Krieger, J. E., Kubo, M., Launer, L. J., Laurikka, J., Lehtimäki, T., Leineweber, K., Lemaitre, R. N., Li, M., Lim, H. E., Lin, H. J., Lin, H., Lind, L., Lindgren, C. M., Lokki, M. L., London, B., Loos, R. J. F., Low, S. K., Lu, Y., Lyytikäinen, L. P., Macfarlane, P. W., Magnusson, P. K., Mahajan, A., Malik, R., Mansur, A. J., Marcus, G. M., Margolin, L., Margulies, K. B., März, W., McManus, D. D., Melander, O., Mohanty, S., Montgomery, J. A., Morley, M. P., Morris, A. P., Müller-Nurasyid, M., Natale, A., Nazarian, S., Neumann, B., Newton-Cheh, C., Niemeijer, M. N., Nikus, K., Nilsson, P., Noordam, R., Oellers, H., Olesen, M. S., Orho-Melander, M., Padmanabhan, S., Pak, H. N., Paré, G., Pedersen, N. L., Pera, J., Pereira, A., Porteous, D., Psaty, B. M., Pulit, S. L., Pullinger, C. R., Rader, D. J., Refsgaard, L., Ribasés, M., Ridker, P. M., Rienstra, M., Risch, L., Roden, D. M., Rosand, J., Rosenberg, M. A., Rost, N., Rotter, J. I., Saba, S., Sandhu, R. K., Schnabel, R. B., Schramm, K., Schunkert, H., Schurman, C., Scott, S. A., Seppälä, I., Shaffer, C., Shah, S., Shalaby, A. A., Shim, J., Shoemaker, M. B., Siland, J. E., Sinisalo, J., Sinner, M. F., Slowik, A., Smith, A. V., Smith, B. H., Smith, J. G., Smith, J. D., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Stricker, B. H., Sun, A., Sun, H., Svendsen, J. H., Tanaka, T., Tanriverdi, K., Taylor, K. D., Teder-Laving, M., Teumer, A., Thériault, S., Trompet, S., Tucker, N. R., Tveit, A., Uitterlinden, A. G., van der Harst, P., van Gelder, I. C., van Wagoner, D. R., Verweij, N., Vlachopoulou, E., Völker, U., Wang, B., Weeke, P. E., Weijs, B., Weiss, R., Weiss, S., Wells, Q. S., Wiggins, K. L., Wong, J. A., Woo, D., Worrall, B. B., Yang, P. S., Yao, J., Yoneda, Z. T., Zeller, T., Zeng, L., Lubitz, S. A., Lunetta, K. L. & Ellinor, P. T., Jun 11 2018, (Accepted/In press) In : Nature Genetics. p. 1-9 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Atrial Fibrillation
Genes
RNA Sequence Analysis
Quantitative Trait Loci

RNA binding protein, HuR, regulates SCN5A expression through stabilizing MEF2C transcription factor mRNA

Zhou, A., Shi, G., Kang, G-J., Xie, A., Liu, H., Jiang, N., Liu, M., Jeong, E. M. & Dudley, S., May 1 2018, In : Journal of the American Heart Association. 7, 9, e007802.

Research output: Contribution to journalArticle

Open Access
MEF2 Transcription Factors
RNA-Binding Proteins
Transcription Factors
Messenger RNA
RNA Stability

The role of the unfolded protein response in arrhythmias

Liu, M. & Dudley, S., Jan 1 2018, In : Channels. 12, 1, p. 335-345 11 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Ion Channels
Cardiac Arrhythmias
Heart Diseases
Proteins
2017
3 Citations (Scopus)

Abnormal sodium channel mRNA splicing in hypertrophic cardiomyopathy

Noyes, A. M., Zhou, A., Gao, G., Gu, L., Day, S., Andrew Wasserstrom, J. & Dudley, S. C., Dec 15 2017, In : International Journal of Cardiology. 249, p. 282-286 5 p.

Research output: Contribution to journalArticle

Sodium Channels
Hypertrophic Cardiomyopathy
Unfolded Protein Response
Messenger RNA
Real-Time Polymerase Chain Reaction
6 Citations (Scopus)

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts:A mechanism underlying RV fibrosis associated with cigarette smoke exposure

Vang, A., Clements, R. T., Chichger, H., Kue, N., Allawzi, A., O’Connell, K., Jeong, E. M., Dudley, S. C., Sakhatskyy, P., Lu, Q., Zhang, P., Rounds, S. & Choudhary, G., May 4 2017, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 312, 5, p. L669-L677

Research output: Contribution to journalArticle

Nicotinic Receptors
Smoke
Tobacco Products
Fibrosis
Collagen

Impact of treatment crossovers on clinical outcomes in the rate and rhythm control strategies for atrial fibrillation: Insights from the AFFIRM (Atrial Fibrillation Follow-up Investigation of Rhythm Management) trial

Maan, A., Zhang, Z., Qin, Z., Wang, Y., Dudley, S., Dabhadakar, K., Refaat, M., Mansour, M., Ruskin, J. N. & Heist, E. K., Jul 1 2017, In : PACE - Pacing and Clinical Electrophysiology. 40, 7, p. 770-778 9 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Confidence Intervals
Mortality
Therapeutics
4 Citations (Scopus)

Role of protein kinase C in metabolic regulation of the cardiac Na+ channel

Liu, M., Shi, G., Yang, K. C., Gu, L., Kanthasamy, A. G., Anantharam, V. & Dudley, S. C., Mar 1 2017, In : Heart Rhythm. 14, 3, p. 440-447 8 p.

Research output: Contribution to journalArticle

Protein Kinase C
Reactive Oxygen Species
NAD
Phospholipase D
Down-Regulation
10 Citations (Scopus)

SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR

I. Polina, K.R. Murphy, R.T. Clements & G. Koren, B.R. Choi, D. Terentyev, 2017, In : Cardiovascular Research. 113, 3, p. 343-353

Research output: Contribution to journalArticle

2016
3 Citations (Scopus)

Association between Heat Shock Protein-60 and Development of Atrial Fibrillation: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)

Maan, A., Jorgensen, N. W., Mansour, M., Dudley, S., Jenny, N. S., Defilippi, C., Szklo, M., Alonso, A., Refaat, M. M., Ruskin, J., Heckbert, S. R. & Heist, E. K., Dec 1 2016, In : PACE - Pacing and Clinical Electrophysiology. 39, 12, p. 1373-1378 6 p.

Research output: Contribution to journalArticle

Chaperonin 60
Atrial Fibrillation
Atherosclerosis
Atrial Remodeling
Heat-Shock Proteins
1 Citation (Scopus)

Associations of prolonged QTc in sickle cell disease

Indik, J. H., Nair, V., Rafikov, R., Nyotowidjojo, I. S., Bisla, J., Kansal, M., Parikh, D. S., Robinson, M., Desai, A., Oberoi, M., Gupta, A., Abbasi, T., Khalpey, Z., Patel, A. R., Lang, R. M., Dudley, S. C., Choi, B. R., Garcia, J. G. N., Machado, R. F. & Desai, A. A., Oct 1 2016, In : PloS one. 11, 10, e0164526.

Research output: Contribution to journalArticle

sickle cell anemia
Sickle Cell Anemia
Hazards
electrocardiography
Electrocardiography
4 Citations (Scopus)

Cardiac Sodium Channel Mutations: Why so Many Phenotypes?

Liu, M., Yang, K. C. & Dudley, S., Jan 1 2016, Na Channels from Phyla to Function, 2016. Noskov, S. Y. & French, R. J. (eds.). Academic Press Inc., p. 513-559 47 p. (Current Topics in Membranes; vol. 78).

Research output: Chapter in Book/Report/Conference proceedingChapter

Sodium Channels
Phenotype
Mutation
Action Potentials
Brugada Syndrome
10 Citations (Scopus)

Obstructive Sleep Apnea and Circulating Potassium Channel Levels

Jiang, N., Zhou, A., Prasad, B., Zhou, L., Doumit, J., Shi, G., Imran, H., Kaseer, B., Millman, R. & Dudley, S. C., Aug 1 2016, In : Journal of the American Heart Association. 5, 8, e003666.

Research output: Contribution to journalArticle

Potassium Channels
Obstructive Sleep Apnea
Continuous Positive Airway Pressure
Sudden Cardiac Death
Apnea
24 Citations (Scopus)

Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction

Jeong, E. M., Chung, J., Liu, H., Go, Y., Gladstein, S., Farzaneh-Far, A., Lewandowski, E. D. & Dudley, S. C., May 1 2016, In : Journal of the American Heart Association. 5, 5, e003046.

Research output: Contribution to journalArticle

Insulin Resistance
High Fat Diet
Oxidative Stress
Glucose
Diabetes Mellitus
1 Citation (Scopus)

Serum amine-based metabolites and their association with outcomes in primary prevention implantable cardioverter-defibrillator patients

Zhang, Y., Blasco-Colmenares, E., Harms, A. C., London, B., Halder, I., Singh, M., Dudley, S. C., Gutmann, R., Guallar, E., Hankemeier, T., Tomaselli, G. F. & Cheng, A., Jan 1 2016, In : Europace. 18, 9, p. 1383-1390 8 p.

Research output: Contribution to journalArticle

Implantable Defibrillators
Primary Prevention
Amines
Kynurenine
Serum
2015
3 Citations (Scopus)

A circulating biomarker risk-prediction model correlates with CHADS-2 risk score in chronic atrial fibrillation

Negi, S. I., Greener, I., Anand, A. & Dudley, S., Mar 1 2015, In : IJC Metabolic and Endocrine. 6, p. 24-26 3 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Biomarkers
Oxygen
Oxidative Stress
Inflammation
2 Citations (Scopus)

Correlation between subclinical heart disease and cardiovascular risk profiles in an urban emergency department population with elevated blood pressures: A pilot study

Prendergast, H. M., Colla, J., Patel, N., Del Rios, M., Marcucci, J., Scholz, R., Ngwang, P., Cappitelli, K., Daviglus, M. & Dudley, S., Jun 1 2015, In : Journal of Emergency Medicine. 48, 6, p. 756-761 6 p.

Research output: Contribution to journalArticle

Hospital Emergency Service
Heart Diseases
Blood Pressure
Left Ventricular Hypertrophy
Population
25 Citations (Scopus)

Diastolic dysfunction: Potential new diagnostics and therapies

Jeong, E. M. & Dudley, S. C., Jan 1 2015, In : Circulation Journal. 79, 3, p. 470-477 8 p.

Research output: Contribution to journalArticle

Diastolic Heart Failure
Systolic Heart Failure
Epidemiology
Oxidative Stress
Therapeutics
13 Citations (Scopus)

Effect of Angiotensin-Converting Enzyme Inhibitors and Receptor Blockers on Appropriate Implantable Cardiac Defibrillator Shock in Patients With Severe Systolic Heart Failure (from the GRADE Multicenter Study)

AlJaroudi, W. A., Refaat, M. M., Habib, R. H., Al-Shaar, L., Singh, M., Gutmann, R., Bloom, H. L., Dudley, S. C., Ellinor, P. T., Saba, S. F., Shalaby, A. A., Weiss, R., McNamara, D. M., Halder, I. & London, B., Apr 1 2015, In : American Journal of Cardiology. 115, 7, p. 924-931 8 p.

Research output: Contribution to journalArticle

Systolic Heart Failure
Implantable Defibrillators
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Multicenter Studies
21 Citations (Scopus)

Inactivation of Endothelial Small/Intermediate Conductance of Calcium-Activated Potassium Channels Contributes to Coronary Arteriolar Dysfunction in Diabetic Patients

Liu, Y., Xie, A., Singh, A. K., Ehsan, A., Choudhary, G., Dudley, S., Sellke, F. W. & Feng, J., Aug 24 2015, In : Journal of the American Heart Association. 4, 8, p. e002062

Research output: Contribution to journalArticle

Intermediate-Conductance Calcium-Activated Potassium Channels
Small-Conductance Calcium-Activated Potassium Channels
Arterioles
Glycosylated Hemoglobin A
Endothelium
10 Citations (Scopus)

Left Ventricular Dilatation Increases the Risk of Ventricular Arrhythmias in Patients With Reduced Systolic Function

Aleong, R. G., Mulvahill, M. J., Halder, I., Carlson, N. E., Singh, M., Bloom, H. L., Dudley, S. C., Ellinor, P. T., Shalaby, A., Weiss, R., Gutmann, R., Sauer, W. H., Narayanan, K., Chugh, S. S., Saba, S. & London, B., Jul 31 2015, In : Journal of the American Heart Association. 4, 8, p. e001566

Research output: Contribution to journalArticle

Cardiac Arrhythmias
Dilatation
Shock
Heart-Assist Devices
Stroke Volume
31 Citations (Scopus)

Mechanisms of Sudden Cardiac Death: Oxidants and Metabolism

Yang, K. C., Kyle, J. W., Makielski, J. C. & Dudley, S. C., Jun 5 2015, In : Circulation research. 116, 12, p. 1937-1955 19 p.

Research output: Contribution to journalArticle

Sudden Cardiac Death
Ion Channels
Oxidants
Cardiac Arrhythmias
Oxidation-Reduction
4 Citations (Scopus)

Renin-Angiotensin Activation and Oxidative Stress in Early Heart Failure with Preserved Ejection Fraction

Negi, S. I., Jeong, E. M., Shukrullah, I., Veleder, E., Jones, D. P., Fan, T. H. M., Varadarajan, S., Danilov, S. M., Fukai, T. & Dudley, S. C., Jan 1 2015, In : BioMed Research International. 2015, 825027.

Research output: Contribution to journalArticle

Oxidative stress
Angiotensins
Renin
Oxidative Stress
Heart Failure
21 Citations (Scopus)
arrhythmia
heart diseases
Unfolded Protein Response
Cardiac Arrhythmias
Heart Diseases
2014
2 Citations (Scopus)

Antihypertensive Medications and Diastolic Dysfunction Progression in an African American Population

Prendergast, H. M., Dudley, S., Brown, M., Daviglus, M., Kane, J., Bradshaw Bunney, E., Marcucci, J. & Sanyaolu, R., Nov 20 2014, In : High Blood Pressure and Cardiovascular Prevention. 21, 4, p. 269-274 6 p.

Research output: Contribution to journalArticle

African Americans
Antihypertensive Agents
Calcium Channel Blockers
Population
Cohort Studies
37 Citations (Scopus)

Cardiac sodium channel mutations: Why so many phenotypes?

Liu, M., Yang, K. C. & Dudley, S. C., Jan 1 2014, In : Nature Reviews Cardiology. 11, 10, p. 607-615 9 p.

Research output: Contribution to journalReview article

Sodium Channels
Phenotype
Mutation
Genetic Association Studies
Brugada Syndrome
15 Citations (Scopus)

Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating csrc tyrosine kinase

Yang, K. C., Rutledge, C. A., Mao, M., Bakhshi, F. R., Xie, A., Liu, H., Bonini, M. G., Patel, H. H., Minshall, R. D. & Dudley, S. C., Jan 1 2014, In : Circulation: Arrhythmia and Electrophysiology. 7, 4, p. 701-710 10 p.

Research output: Contribution to journalArticle

Caveolin 1
Gap Junctions
Protein-Tyrosine Kinases
Homeostasis
Cardiac Arrhythmias
22 Citations (Scopus)

C-Src kinase inhibition reduces arrhythmia inducibility and connexin43 dysregulation after myocardial infarction

Rutledge, C. A., Ng, F. S., Sulkin, M. S., Greener, I. D., Sergeyenko, A. M., Liu, H., Gemel, J., Beyer, E. C., Sovari, A. A., Efimov, I. R. & Dudley, S. C., Mar 11 2014, In : Journal of the American College of Cardiology. 63, 9, p. 928-934 7 p.

Research output: Contribution to journalArticle

Connexin 43
src-Family Kinases
Cardiac Arrhythmias
Myocardial Infarction
Cicatrix
8 Citations (Scopus)

Enhanced risk profiling of implanted defibrillator shocks with circulating SCN5A mRNA splicing variants: A pilot trial

Gao, G., Brahmanandam, V., Raicu, M., Gu, L., Zhou, L., Kasturirangan, S., Shah, A., Negi, S. I., Wood, M. R., Desai, A. A., Tatooles, A., Schwartz, A. & Dudley, S. C., Jun 3 2014, In : Journal of the American College of Cardiology. 63, 21, p. 2261-2269 9 p.

Research output: Contribution to journalArticle

Defibrillators
Shock
Heart Failure
Implantable Defibrillators
Messenger RNA
31 Citations (Scopus)

Mitochondria and arrhythmias

Yang, K. C., Bonini, M. G. & Dudley, S., Jan 1 2014, In : Free Radical Biology and Medicine. 71, p. 351-361 11 p.

Research output: Contribution to journalReview article

Mitochondria
Cardiac Arrhythmias
Reactive Oxygen Species
Adenosine Triphosphate
Ion Channels
3 Citations (Scopus)

New diagnostic and therapeutic possibilities for diastolic heart failure

Jeong, E. M. & Dudley, S. C., Feb 1 2014, In : Rhode Island medical journal (2013). 97, 2, p. 35-37 3 p.

Research output: Contribution to journalArticle

Diastolic Heart Failure
Heart Failure
Systolic Heart Failure
Therapeutics
Incidence
9 Citations (Scopus)

Nitroglycerin tolerance in caveolin-1 deficient mice

Mao, M., Varadarajan, S., Fukai, T., Bakhshi, F. R., Chernaya, O., Dudley, S. C., Minshall, R. D. & Bonini, M. G., Aug 26 2014, In : PLoS One. 9, 8, e104101.

Research output: Contribution to journalArticle

Caveolin 1
Nitroglycerin
mice
Peroxynitrous Acid
Nitrates
1 Citation (Scopus)

Progression of left ventricular diastolic dysfunction in ethnic minorities

Prendergast, H. M., Dudley, S., Kane, J., Daviglus, M., Marcucci, J., Acosta, A., Bunney, E. B., Richardson, D. & O'Neal, T., Jan 1 2014, In : High Blood Pressure and Cardiovascular Prevention. 21, 3, p. 205-211 7 p.

Research output: Contribution to journalArticle

Left Ventricular Dysfunction
Population
Cohort Studies
Retrospective Studies
Diastolic Heart Failure
6 Citations (Scopus)

Targeting the unfolded protein response in heart diseases

Liu, M. & Dudley, S. C., Jan 1 2014, In : Expert Opinion on Therapeutic Targets. 18, 7, p. 719-723 5 p.

Research output: Contribution to journalReview article

Unfolded Protein Response
Heart Diseases
Proteins
Medical problems
Reperfusion
2013

Biophysics of Membrane Currents in Heart Failure

Liu, M., Brahmanandam, V. M. & Dudley, S., 2013, The Biophysics of the Failing Heart. Solaro, R. J. & Tardif, J. C. (eds.). 1st ed. Springer, p. 63-90

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Mitochondria and arrhythmias

Rutledge, C. & Dudley, S., Jul 1 2013, In : Expert Review of Cardiovascular Therapy. 11, 7, p. 799-801 3 p.

Research output: Contribution to journalReview article

Heart Mitochondria
Sodium Channels
Potassium Channels
Sudden Cardiac Death
Biomedical Research
32 Citations (Scopus)

Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy

Liu, M., Gu, L., Sulkin, M. S., Liu, H., Jeong, E. M., Greener, I., Xie, A., Efimov, I. R. & Dudley, S., Jan 1 2013, In : Journal of Molecular and Cellular Cardiology. 54, 1, p. 25-34 10 p.

Research output: Contribution to journalArticle

Sodium Channels
Cardiomyopathies
NAD
Down-Regulation
Reactive Oxygen Species
57 Citations (Scopus)

Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death

Sovari, A. A., Rutledge, C. A., Jeong, E. M., Dolmatova, E., Arasu, D., Liu, H., Vahdani, N., Gu, L., Zandieh, S., Xiao, L., Bonini, M. G., Duffy, H. S. & Dudley, S. C., Jun 1 2013, In : Circulation: Arrhythmia and Electrophysiology. 6, 3, p. 623-631 9 p.

Research output: Contribution to journalArticle

Connexin 43
Sudden Death
Reactive Oxygen Species
Mitochondria
Oxidative Stress
14 Citations (Scopus)
Stem cells
Mesenchymal Stromal Cells
Myocardial Infarction
Modulation
Cardiomyoplasty
18 Citations (Scopus)

Oxidative stress and atrial fibrillation: Finding a missing piece to the puzzle

Yang, K. C. & Dudley, S. C., Oct 15 2013, In : Circulation. 128, 16, p. 1724-1726 3 p.

Research output: Contribution to journalEditorial

Heart Conduction System
Calcium-Calmodulin-Dependent Protein Kinase Type 2
NADPH Oxidase
Atrial Fibrillation
Cardiac Arrhythmias

Preface

Sovari, A. A., Kocheril, A. G. & Dudley, S. C., Feb 1 2013, Ventricular Arrhythmia: From Principles to Patients. Nova Science Publishers, Inc.

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

9 Citations (Scopus)

RBM25/LUC7L3 Function in Cardiac Sodium Channel Splicing Regulation of Human Heart Failure

Gao, G. & Dudley, S. C., Jan 1 2013, In : Trends in Cardiovascular Medicine. 23, 1, 1 p.

Research output: Contribution to journalReview article

Sodium Channels
Alternative Splicing
Heart Failure
Messenger RNA
Anti-Arrhythmia Agents
2 Citations (Scopus)

Role of oxidative stress in ventricular arrhythmias

Sovari, A. A., Small, O., Bonini, M. G., Kocheril, A. G. & Dudley, S. C., Feb 1 2013, Ventricular Arrhythmia: From Principles to Patients. Nova Science Publishers, Inc., p. 77-93 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cardiac Arrhythmias
Reactive Oxygen Species
Oxidative Stress
Antioxidants
Lipids