Keyphrases
5-aminosalicylic Acid (5-ASA)
32%
Activity-based Probes
32%
Acyl
19%
Adenylation
32%
ADP-ribosylation
32%
Antibacterial Agents
32%
Antimycobacterial Activity
41%
Biological Evaluation
32%
Biosynthetic Pathway
11%
Biotin Ligase
32%
Cephem
32%
Disease States
13%
Electrophilic
10%
Functional Characterization
32%
Homoserine
32%
Human Microbiome
13%
Hydrolysis
13%
Infection-related Mortality
15%
Lactams
32%
Mechanism of Action
11%
Metabolically Stable
32%
Microbiome
32%
Mycobacterium
18%
Mycobacterium Tuberculosis (M. tb)
100%
Mycobactin
32%
Non-replicating
11%
Nucleophilic
32%
Orally Active
32%
Overexpressing
11%
PLP-dependent Enzymes
32%
Polyfluorinated
32%
Prodrug
35%
Pyrazinoic Acid
65%
Resistant Strains
21%
Rifamycin
24%
Rifamycin Antibiotics
32%
Salicylic Acid
27%
Salicylic Acid Analogues
32%
Siderophore Production
32%
Structural Characterization
32%
Structure-activity Relationship
32%
Sulfamide
19%
Synthetic Evaluation
32%
Transacetylase
32%
Tuberculosis
46%
Tuberculosis Drugs
14%
Tuberculosis Treatment
14%
Via Resistance
32%
Warhead
26%
β-lactamase
21%
Pharmacology, Toxicology and Pharmaceutical Science
Acyltransferase
9%
Adenosine Diphosphate
32%
Alkyne
32%
Aminosalicylic Acid
32%
Antibacterial Activity
6%
Antibiotics
32%
Antiinfective Agent
39%
Antimycobacterial Agent
41%
Beta Lactam Antibiotic
10%
Bioactivation
7%
Bioavailability
9%
Biotin
32%
Carboxylate
6%
Cephem
32%
Diseases
15%
Infection
57%
Infectious Agent
6%
Iron
18%
Lactam
32%
Ligase
32%
Lysine
32%
Microbiome
35%
Minimum Inhibitory Concentration
6%
Mycobacteria
17%
Mycobacterium abscessus
6%
Mycobacterium Tuberculosis
98%
Penicillinase
21%
Pharmacokinetics
13%
Prodrug
35%
Pyrazinamide
13%
Pyrazinoic Acid
65%
Rifamycin
32%
Salicylic Acid
32%
Salicylic Acid Derivative
9%
Siderophore
32%
Staphylococcus Aureus
6%
Structure Activity Relationship
32%
Sulfanilamide
19%
Target Activity
6%
Biochemistry, Genetics and Molecular Biology
ADP-ribosylation
32%
Anabolism
23%
Antimicrobial Activity
10%
Bactericidal Activity
8%
Binding Affinity
10%
Coenzyme A
10%
Crystal Structure
10%
Drug Disposition
8%
Enzyme
57%
Infectious Agent
8%
Isothermal Titration Calorimetry
10%
Loss of Function Mutation
10%
Lysine
12%
Mycobacteria
8%
Mycobacterium abscessus
8%
Mycobacterium Tuberculosis
68%
N-Acetyltransferase
32%
Nucleophilicity
32%
Pharmacokinetics
8%
Protein Catabolism
10%
Structure Activity Relation
32%
Whole Cell
14%