Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Protein structural biophysics driving drug discovery for cardiac calcium transport regulation, producing translational advances and mechanistic insights
Thomas, D. D. (PI), Aldrich, C. (CoI) & Rebbeck, R. T. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/24 → 4/30/29
Project: Research project
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Skeletal muscle protein structural dynamics and function drive applications to drug discovery
Thomas, D. D. (PI), Cornea, R. L. (CoI), Lowe, D. A. (CoI) & Rebbeck, R. T. (Co-Principal Investigator)
NIH NIAMS NATL INST OF ARTHRIT
5/1/23 → 4/30/28
Project: Research project
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The NKA-FXYD interactome in Health and Disease
Rebbeck, R. T. (PI) & Cornea, R. L. (Prior Principal Investigator)
LOYOLA UNIVERSITY OF CHICAGO, NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
4/1/22 → 3/31/26
Project: Research project
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Development of a Mirror-Image Natural Product as an Antiarrhythmic Therapeutic
Rebbeck, R. T. (PI) & Cornea, R. L. (Prior Principal Investigator)
VANDERBILT UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
3/17/20 → 2/28/24
Project: Research project
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Role of Calmodulin Structure in Cardiac Calcium Channel
Rebbeck, R. T. (PI)
AMERICAN HEART ASSOCIATION, INC
7/1/16 → 6/30/18
Project: Research project
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ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2-/- MiceS
Gochman, A., Do, T. Q., Kim, K., Schwarz, J. A., Thorpe, M. P., Blackwell, D. J., Ritschel, P. A., Smith, A. N., Rebbeck, R. T., Akers, W. S., Cornea, R. L., Laver, D. R., Johnston, J. N. & Knollmann, B. C., Mar 1 2024, In: Molecular Pharmacology. 105, 3, p. 194-201 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors
Rebbeck, R. T., Svensson, B., Zhang, J., Samsó, M., Thomas, D. D., Bers, D. M. & Cornea, R. L., Dec 2024, In: Nature communications. 15, 1, 5120.Research output: Contribution to journal › Article › peer-review
Open Access -
Cardiomyopathy-associated variants alter the structure and function of the α-actinin-2 actin-binding domain
Atang, A. E., Rebbeck, R. T., Thomas, D. D. & Avery, A. W., Aug 30 2023, In: Biochemical and Biophysical Research Communications. 670, p. 12-18 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5
Guhathakurta, P., Rebbeck, R. T., Denha, S. A., Keller, A. R., Carter, A. L., Atang, A. E., Svensson, B., Thomas, D. D., Hays, T. S. & Avery, A. W., Mar 2023, In: Journal of Biological Chemistry. 299, 3, 102956.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators
Roopnarine, O., Yuen, S. L., Thompson, A. R., Roelike, L. N., Rebbeck, R. T., Bidwell, P. A., Aldrich, C. C., Cornea, R. L. & Thomas, D. D., Dec 2023, In: Scientific reports. 13, 1, 10673.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations