1983 …2024

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
Article

MeIQx (2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline): metabolism in humans and urinary metabolites in human populations.

Tannenbaum, S. R., Stillwell, W. G., Ji, H., Skipper, P. L., Yu, M. C., Ross, R. K., Henderson, B. E., Turesky, R. J. & Gross, G. A., 1995, In : Princess Takamatsu symposia. 23, p. 197-206 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

Turesky, R. J., Lang, N. P., Butler, M. A., Teitel, C. H. & Kadlubar, F. F., Oct 1 1991, In : Carcinogenesis. 12, 10, p. 1839-1845 7 p.

Research output: Contribution to journalArticle

377 Scopus citations
Open Access
6 Scopus citations

Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates.

Adamson, R. H., Snyderwine, E. G., Thorgeirsson, U. P., Schut, H. A., Turesky, R. J., Thorgeirsson, S. S., Takayama, S. & Sugimura, T., 1990, In : Princess Takamatsu symposia. 21, p. 289-301 13 p.

Research output: Contribution to journalArticle

29 Scopus citations
4 Scopus citations
170 Scopus citations

Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxication pathway catalyzed by cytochrome P450 1A2

Langouët, S., Welti, D. H., Kerriguy, N., Fay, L. B., Huynh-Ba, T., Markovic, J., Guengerich, F. P., Guillouzo, A. & Turesky, R. J., Jan 1 2001, In : Chemical research in toxicology. 14, 2, p. 211-221 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

Metabolism of food-derived heterocyclic amines in nonhuman primates

Snyderwine, E. G., Turesky, R. J., Turteltaub, K. W., Davis, C. D., Sadrieh, N., Schut, H. A. J., Nagao, M., Sugimura, T., Thorgeirsson, U. P., Adamson, R. H. & Thorgeirsson, S. S., May 12 1997, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 376, 1-2, p. 203-210 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2

Turesky, R. J., Guengerich, F. P., Guillouzo, A. & Langouët, S., Sep 30 2002, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 506-507, p. 187-195 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Metabolism of ochratoxin A: Absence of formation of genotoxic derivatives by human and rat enzymes

Gautier, J. C., Richoz, J., Welti, D. H., Markovic, J., Gremaud, E., Peter Guengerich, F. & Turesky, R. J., Feb 1 2001, In : Chemical research in toxicology. 14, 1, p. 34-45 12 p.

Research output: Contribution to journalArticle

93 Scopus citations
12 Scopus citations

Metabolism of the food-borne mutagen/carcinogen 2-amino-3,8-dimethylimidazo[4,5-ƒ]quinoxaline in the rat: Assessment of biliary metabolites for genotoxicity

Turesky, R. J., Aeschbacher, H. U., Malnoöe, A. & Würzner, H. P., 1988, In : Food and Chemical Toxicology. 26, 2, p. 105-110 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Metabolism of the food-borne mutagen 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline in humans

Turesky, R. J., Garner, R. C., Welti, D. H., Richoz, J., Leveson, S. H., Dingley, K. H., Turteltaub, K. W. & Fay, L. B., Apr 8 1998, In : Chemical Research in Toxicology. 11, 3, p. 217-225 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Metabolism of the food-derived carcinogen 2-amino-3,8-dimethylimidazo[4,5,-f)quinoxaline (MeIQx) in nonhuman primates

Snyderwine, E. G., Welti, D. H., Davis, C. D., Fay, L. B. & Turesky, R. J., Jun 1 1995, In : Carcinogenesis. 16, 6, p. 1377-1384 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Metabolism of the food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes

Langouët, S., Welti, D. H., Kerriguy, N., Fay, L. B., Guengerich, F. P., Guillouzo, A. & Turesky, R. J., Jan 1 2001, In : Advances in experimental medicine and biology. 500, p. 459-462 4 p.

Research output: Contribution to journalArticle

Metabolism of the Food Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in Nonhuman Primates Undergoing Carcinogen Bioassay

Snyderwine, E. G., Welti, D. H., Fay, L. B., Wrüzner, H. P. & Turesky, R. J., Nov 1 1992, In : Chemical Research in Toxicology. 5, 6, p. 843-851 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes

Bellamri, M., Le Hegarat, L., Turesky, R. J. & Langouët, S., Feb 20 2017, In : Chemical research in toxicology. 30, 2, p. 657-668 12 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Methemoglobin Formation and Characterization of Hemoglobin Adducts of Carcinogenic Aromatic Amines and Heterocyclic Aromatic Amines

Pathak, K. V., Chiu, T. L., Amin, E. A. & Turesky, R. J., Mar 21 2016, In : Chemical research in toxicology. 29, 3, p. 255-269 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Method for Biomonitoring DNA Adducts in Exfoliated Urinary Cells by Mass Spectrometry

Yun, B. H., Bellamri, M., Rosenquist, T. A. & Turesky, R. J., Aug 21 2018, In : Analytical chemistry. 90, 16, p. 9943-9950 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
8 Scopus citations

Methyluric acids: Chemical markers of oxidation in coffee, tea, and cocoa

Stadler, R. H. & Turesky, R. J., Dec 1 2000, In : ACS Symposium Series. 754, p. 385-393 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Multiclass Carcinogenic DNA Adduct Quantification in Formalin-Fixed Paraffin-Embedded Tissues by Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry

Guo, J., Yun, B. H., Upadhyaya, P., Yao, L., Krishnamachari, S., Rosenquist, T. A., Grollman, A. P. & Turesky, R. J., May 3 2016, In : Analytical chemistry. 88, 9, p. 4780-4787 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in human lymphoblastoid cells

Leong-Morgenthaler, P. M., Op Het Velt, C., Jaccaud, E. & Turesky, R. J., Oct 1 1998, In : Carcinogenesis. 19, 10, p. 1749-1754 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Mutational analysis of the liver, colon and kidney of Big Blue® rats treated with 2-amino-3-methlylimidazo[4,5-f]quinoline

Bol, S. A. M., Horlbeck, J., Markovic, J., De Boer, J. G., Turesky, R. J. & Constable, A., Feb 5 2000, In : Carcinogenesis. 21, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Mutational and DNA binding specificity of the carcinogen 2-amino-3,8- dimethylimidazo[4,5-f]quinoxaline

Solomon, M. S., Morgenthaler, P. M. L., Turesky, R. J. & Essigmann, J. M., Oct 7 1996, In : Journal of Biological Chemistry. 271, 31, p. 18368-18374 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing

Hoang, M. L., Chen, C. H., Sidorenko, V. S., He, J., Dickman, K. G., Yun, B. H., Moriya, M., Niknafs, N., Douville, C., Karchin, R., Turesky, R. J., Pu, Y. S., Vogelstein, B., Papadopoulos, N., Grollman, A. P., Kinzler, K. W. & Rosenquist, T. A., Aug 7 2013, In : Science Translational Medicine. 5, 197, 197ra102.

Research output: Contribution to journalArticle

138 Scopus citations

Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity

Lawana, V., Um, S. Y., Rochet, J. C., Turesky, R. J., Shannahan, J. H. & Cannon, J. R., Jan 1 2020, In : Toxicological Sciences. 173, 1, p. 171-188 18 p.

Research output: Contribution to journalArticle

New approaches for biomonitoring exposure to the human carcinogen aristolochic acid

Yun, B. H., Sidorenko, V. S., Rosenquist, T. A., Dickman, K. G., Grollman, A. P. & Turesky, R. J., Jul 1 2015, In : Toxicology Research. 4, 4, p. 763-776 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

Springer, S. U., Chen, C. H., Del Carmen Rodriguez Pena, M., Li, L., Douville, C., Wang, Y., Cohen, J. D., Taheri, D., Silliman, N., Schaefer, J., Ptak, J., Dobbyn, L., Papoli, M., Kinde, I., Afsari, B., Tregnago, A. C., Bezerra, S. M., Vandenbussche, C., Fujita, K., Ertoy, D. & 20 others, Cunha, I. W., Yu, L., Bivalacqua, T. J., Grollman, A. P., Diaz, L. A., Karchin, R., Danilova, L., Huang, C. Y., Shun, C. T., Turesky, R. J., Yun, B. H., Rosenquist, T. A., Pu, Y. S., Hruban, R. H., Tomasetti, C., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Dickman, K. G. & Netto, G. J., Mar 20 2018, In : eLife. 7, e32143.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
67 Scopus citations

Novel Transgenic Mouse Model for Studying Human Serum Albumin as a Biomarker of Carcinogenic Exposure

Sheng, J., Wang, Y., Turesky, R. J., Kluetzman, K., Zhang, Q. Y. & Ding, X., May 16 2016, In : Chemical research in toxicology. 29, 5, p. 797-809 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

N-oxidative metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in humans: Excretion of the N2-glucuronide conjugate of 2- hydroxyamino-MeIQx in urine

Stillwell, W. G., Turesky, R. J., Sinha, R. & Tannenbaum, S. R., Oct 15 1999, In : Cancer Research. 59, 20, p. 5154-5159 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Ochratoxin A induces oxidative DNA damage in liver and kidney after oral dosing to rats

Kamp, H. G., Eisenbrand, G., Janzowski, C., Kiossev, J., Latendresse, J. R., Schlatter, J. & Turesky, R. J., Dec 1 2005, In : Molecular Nutrition and Food Research. 49, 12, p. 1160-1167 8 p.

Research output: Contribution to journalArticle

84 Scopus citations
10 Scopus citations

Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidations

Stadler, R. H., Richoz, J., Turesky, R., Welti, D. H. & Fay, L. B., Jan 1 1996, In : Free Radical Research. 24, 3, p. 225-240 16 p.

Research output: Contribution to journalArticle

36 Scopus citations

Oxidative damage and stress response from ochratoxin A exposure in rats

Gautier, J. C., Holzhaeuser, D., Markovic, J., Gremaud, E., Schilter, B. & Turesky, R. J., May 15 2001, In : Free Radical Biology and Medicine. 30, 10, p. 1089-1098 10 p.

Research output: Contribution to journalArticle

150 Scopus citations

Phase I and phase II xenobiotic reactions and metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in aggregating liver cell cultures

Schilter, B., Turesky, R. J., Juillerat, M., Honegger, P. & Guigoz, Y., Mar 9 1993, In : Biochemical Pharmacology. 45, 5, p. 1087-1096 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Purification of the food-borne carcinogens 2-amino-3-methylimidazo [4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in heated meat products by immunoaffinity chromatography

Turesky, R. J., Forster, C. M., Aeschbacher, H. U., Würzner, H. P., Skipper, P. L., Trudel, L. J. & Tannenbaum, S. R., Jan 1 1989, In : Carcinogenesis. 10, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

56 Scopus citations

Qualitative and quantitative characterization of mutagens in commercial beef extract

Turesky, R. J., Wishnok, J. S., Tannenbaum, S. R., Pfund, R. A. & Buchi, G. H., Dec 1 1983, In : Carcinogenesis. 4, 7, p. 863-866 4 p.

Research output: Contribution to journalArticle

67 Scopus citations
Open Access
6 Scopus citations
38 Scopus citations

Quantitation of 13 heterocyclic aromatic amines in cooked beef, pork, and chicken by liquid chromatography-electrospray ionization/tandem mass spectrometry

Ni, W., McNaughton, L., LeMaster, D. M., Sinha, R. & Turesky, R. J., Jan 9 2008, In : Journal of agricultural and food chemistry. 56, 1, p. 68-78 11 p.

Research output: Contribution to journalArticle

68 Scopus citations

Quantitation of Apurinic/Apyrimidinic Sites in Isolated DNA and in Mammalian Tissue with a Reduced Level of Artifacts

Chen, H., Yao, L., Brown, C., Rizzo, C. J. & Turesky, R. J., Jun 4 2019, In : Analytical chemistry. 91, 11, p. 7403-7410 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Quantitation of carcinogenic heterocyclic aromatic amines and detection of novel heterocyclic aromatic amines in cooked meats and grill scrappings by HPLC/ESI-MS

Turesky, R. J., Taylor, J., Schnackenberg, L., Freeman, J. P. & Holland, R. D., Apr 20 2005, In : Journal of agricultural and food chemistry. 53, 8, p. 3248-3258 11 p.

Research output: Contribution to journalArticle

75 Scopus citations
1 Scopus citations
62 Scopus citations
127 Scopus citations

Rapid Analytical Methods to Measure Pentachlorophenol in Wood

Gremaud, E. & Turesky, R. J., Apr 1997, In : Journal of agricultural and food chemistry. 45, 4, p. 1229-1233 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Rapid biomonitoring of heterocyclic aromatic amines in human urine by tandem solvent solid phase extraction liquid chromatography electrospray ionization mass spectrometry

Holland, R. D., Taylor, J., Schoenbachler, L., Jones, R. C., Freeman, J. P., Miller, D. W., Lake, B. G., Gooderham, N. J. & Turesky, R. J., Aug 1 2004, In : Chemical research in toxicology. 17, 8, p. 1121-1136 16 p.

Research output: Contribution to journalArticle

44 Scopus citations