1983 …2024

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2000

Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage

Collins, A., Brown, J., Bogdanov, M., Cadet, J., Cooke, M., Douki, T., Dunster, C., Eakins, J., Epe, B., Evans, M., Farmer, P., Gedik, C. M., Halliwell, B., Herbert, K., Hofer, T., Hutchinson, R., Jenner, A., Jones, G. D. D., Kasai, H., Kelly, F. & 20 others, Lloret, A., Loft, S., Lunec, J., McEwan, M., Möller, L., Olinski, R., Podmore, I., Poulsen, H., Ravanat, J. L., Rees, J. E., Reetz, F., Shertzer, H., Spiegelhalder, B., Turesky, R., Tyrrell, R., Viña, J., Vinicombe, D., Weimann, A., de Wergifosse, B. & Wood, S. G., Jan 1 2000, In : Free Radical Research. 32, 4, p. 333-341 9 p.

Research output: Contribution to journalArticle

112 Scopus citations

Methyluric acids: Chemical markers of oxidation in coffee, tea, and cocoa

Stadler, R. H. & Turesky, R. J., Dec 1 2000, In : ACS Symposium Series. 754, p. 385-393 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mutational analysis of the liver, colon and kidney of Big Blue® rats treated with 2-amino-3-methlylimidazo[4,5-f]quinoline

Bol, S. A. M., Horlbeck, J., Markovic, J., De Boer, J. G., Turesky, R. J. & Constable, A., Feb 5 2000, In : Carcinogenesis. 21, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

43 Scopus citations
62 Scopus citations
124 Scopus citations
1999

A new modification of the 32P-post-labeling method to recover IQ-DNA adducts as mononucleotides

Ochiai, M., Nakagama, H., Turesky, R. J., Sugimura, T. & Nagao, M., Jan 1 1999, In : Mutagenesis. 14, 2, p. 239-242 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Biomonitoring of heterocyclic aromatic amine metabolites in human urine

Stillwell, W. G., Turesky, R. J., Sinha, R., Skipper, P. L. & Tannenbaum, S. R., Sep 1 1999, In : Cancer Letters. 143, 2, p. 145-148 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Comparison of DNA-adduct and tissue-available dose levels of MeIQx in human and rodent colon following administration of a very low dose

Mauthe, R. J., Dingley, K. H., Leveson, S. H., Freeman, S. P. H. T., Turesky, R. J., Garner, R. C. & Turteltaub, K. W., Feb 4 1999, In : International Journal of Cancer. 80, 4, p. 539-545 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
44 Scopus citations

Evaluation of Escherichia coli DJ4309 expressing human P450 1A2 in mutagenicity testing of complex food mixtures

Constable, A., Varga, N., Josephy, P. D., Guy, P. & Turesky, R. J., Jun 25 1999, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 442, 2, p. 79-87 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inter-individual differences in the metabolism of environmental toxicants: Cytochrome P450 1A2 as a prototype

Guengerich, F. P., Parikh, A., Turesky, R. J. & Josephy, P. D., Jul 16 1999, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 428, 1-2, p. 115-124 10 p.

Research output: Contribution to journalArticle

56 Scopus citations

Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2

Turesky, R. J., Constable, A., Fay, L. B. & Guengerich, F. P., Sep 1 1999, In : Cancer Letters. 143, 2, p. 109-112 4 p.

Research output: Contribution to journalArticle

42 Scopus citations

Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses

Turteltaub, K. W., Dingley, K. H., Curtis, K. D., Malfatti, M. A., Turesky, R. J., Colin Garner, R., Felton, J. S. & Lang, N. P., Sep 1 1999, In : Cancer Letters. 143, 2, p. 149-155 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

N-oxidative metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in humans: Excretion of the N2-glucuronide conjugate of 2- hydroxyamino-MeIQx in urine

Stillwell, W. G., Turesky, R. J., Sinha, R. & Tannenbaum, S. R., Oct 15 1999, In : Cancer Research. 59, 20, p. 5154-5159 6 p.

Research output: Contribution to journalArticle

39 Scopus citations
1998

Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2

Turesky, R. J., Constable, A., Richoz, J., Varga, N., Markovic, J., Martin, M. V. & Guengerich, F. P., Sep 2 1998, In : Chemical research in toxicology. 11, 8, p. 925-936 12 p.

Research output: Contribution to journalArticle

165 Scopus citations

Detection of 8-oxoguanine in cellular DNA using 2,6-diamino-8-oxopurine as an internal standard for high-performance liquid chromatography with electrochemical detection

Ravanat, J. L., Gremaud, E., Markovic, J. & Turesky, R. J., Jun 15 1998, In : Analytical Biochemistry. 260, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Metabolism of the food-borne mutagen 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline in humans

Turesky, R. J., Garner, R. C., Welti, D. H., Richoz, J., Leveson, S. H., Dingley, K. H., Turteltaub, K. W. & Fay, L. B., Apr 8 1998, In : Chemical Research in Toxicology. 11, 3, p. 217-225 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in human lymphoblastoid cells

Leong-Morgenthaler, P. M., Op Het Velt, C., Jaccaud, E. & Turesky, R. J., Oct 1 1998, In : Carcinogenesis. 19, 10, p. 1749-1754 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
1997

Distribution and Quantification of Oil Uptake in French Fries Utilizing a Radiolabeled 14C Palmitic Acid

Saguy, I. S., Gremaud, E., Gloria, H. & Turesky, R. J., Nov 1 1997, In : Journal of agricultural and food chemistry. 45, 11, p. 4286-4289 4 p.

Research output: Contribution to journalArticle

31 Scopus citations

Formation and persistence of DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline in the rat and nonhuman primates

Turesky, R. J., Box, R. M., Markovic, J., Gremaud, E. & Snyderwine, E. G., May 12 1997, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 376, 1-2, p. 235-241 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Measurement of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 8-oxo-7,8-dihydroguanine in isolated DNA exposed to gamma radiation in aqueous solution

Douki, T., Martini, R., Ravanat, J. L., Turesky, R. J. & Cadet, J., Dec 1 1997, In : Carcinogenesis. 18, 12, p. 2385-2391 7 p.

Research output: Contribution to journalArticle

94 Scopus citations

Measurement of oxidized bases in DNA. Comparison between HPLC-EC sand GC-MS assays

Ravanat, J. L., Douki, T., Turesky, R. & Cadet, J., Jan 1 1997, In : Journal de Chimie Physique et de Physico-Chimie Biologique. 94, 2, p. 306-312 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Metabolism of food-derived heterocyclic amines in nonhuman primates

Snyderwine, E. G., Turesky, R. J., Turteltaub, K. W., Davis, C. D., Sadrieh, N., Schut, H. A. J., Nagao, M., Sugimura, T., Thorgeirsson, U. P., Adamson, R. H. & Thorgeirsson, S. S., May 12 1997, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 376, 1-2, p. 203-210 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Rapid Analytical Methods to Measure Pentachlorophenol in Wood

Gremaud, E. & Turesky, R. J., Apr 1997, In : Journal of agricultural and food chemistry. 45, 4, p. 1229-1233 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Rapid Solid-Phase Extraction Method for the Detection of Volatile Nitrosamines in Food

Raoul, S., Gremaud, E., Biaudet, H. & Turesky, R. J., Dec 1997, In : Journal of Agricultural and Food Chemistry. 45, 12, p. 4706-4713 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Urinary excretion of 3-methyladenine after consumption of fish containing high levels of dimethylamine

Fay, L. B., Leaf, C. D., Gremaud, E., Aeschlimann, J. M., Steen, C., Shuker, D. E. G. & Turesky, R. J., May 1997, In : Carcinogenesis. 18, 5, p. 1039-1044 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
1996

DNA adduct formation of the food-derived mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in Nonhuman primates undergoing carcinogen bioassay

Turesky, R. J., Gremaud, E., Markovic, J. & Snyderwine, E. G., Mar 1 1996, In : Chemical Research in Toxicology. 9, 2, p. 403-408 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
32 Scopus citations

Mutational and DNA binding specificity of the carcinogen 2-amino-3,8- dimethylimidazo[4,5-f]quinoxaline

Solomon, M. S., Morgenthaler, P. M. L., Turesky, R. J. & Essigmann, J. M., Oct 7 1996, In : Journal of Biological Chemistry. 271, 31, p. 18368-18374 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidations

Stadler, R. H., Richoz, J., Turesky, R., Welti, D. H. & Fay, L. B., Jan 1 1996, In : Free Radical Research. 24, 3, p. 225-240 16 p.

Research output: Contribution to journalArticle

36 Scopus citations
1995
189 Scopus citations
70 Scopus citations

Dna adduct formation of the food carcinogen 2-amino-3-methylimidazo[4, 5-f]quinoline (iq) in liver, kidney and colo-rectum of rats

Turesky, R. J. & Markovic, J., Sep 1 1995, In : Carcinogenesis. 16, 9, p. 2275-2279 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

In vitro anti- and pro-oxidative effects of natural polyphenols

Stadler, R. H., Markovic, J. & Turesky, R. J., Jan 1 1995, In : Biological Trace Element Research. 47, 1-3, p. 299-305 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

MeIQx (2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline): metabolism in humans and urinary metabolites in human populations.

Tannenbaum, S. R., Stillwell, W. G., Ji, H., Skipper, P. L., Yu, M. C., Ross, R. K., Henderson, B. E., Turesky, R. J. & Gross, G. A., 1995, In : Princess Takamatsu symposia. 23, p. 197-206 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
4 Scopus citations

Metabolism of the food-derived carcinogen 2-amino-3,8-dimethylimidazo[4,5,-f)quinoxaline (MeIQx) in nonhuman primates

Snyderwine, E. G., Welti, D. H., Davis, C. D., Fay, L. B. & Turesky, R. J., Jun 1 1995, In : Carcinogenesis. 16, 6, p. 1377-1384 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
1994
52 Scopus citations

Formation of DNA adducts by the food mutagen 2-amino-3,4,8-trimethyl-3h-imidazo [4,8-f]quinoxaline (4,8-dimeiqx) in vitro and in vivo. identification of a N-(2'-deoxyguanosin-8-yl)-4,8-dimeiqx adduct

Frandsen, H., Grivas, S., Turesky, R. J., Andersson, R., Dragsted, L. O. & Larsen, J. C., Nov 1 1994, In : Carcinogenesis. 15, 11, p. 2553-2558 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes

Kaderlik, K. R., Mulder, G. J., Turesky, R. J., Lang, N. P., Teitel, C. H., Chiarelli, M. P. & Kadlubar, F. F., Aug 1 1994, In : Carcinogenesis. 15, 8, p. 1695-1701 7 p.

Research output: Contribution to journalArticle

85 Scopus citations

Human Urinary Excretion of Sulfamate and Glucuronide Conjugates of 2-Amino-3, 8-dimethylimidazo[4, 5-f]quinoxaline (MelQx)1

Stillwell, W. G., Turesky, R. J., Gross, G. A., Skipper, P. L. & Tannenbaum, S. R., Jul 1 1994, In : Cancer Epidemiology Biomarkers and Prevention. 3, 5, p. 399-405 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Species differences in metabolism of heterocyclic aromatic amines, human exposure, and biomonitoring

Turesky, R. J., Gross, G. A., Stillwell, W. G., Skipper, P. L. & Tannenbaum, S. R., Jan 1 1994, In : Environmental health perspectives. 102, SUPPL. 6, p. 47-51 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Synthesis of Multiply-Labeled [15N3,13C1]-8-Oxo-Substituted Purine Bases and Their Corresponding 2′-Deoxynucleosides

Stadler, R. H., Staempfli, A. A., Fay, L. B., Turesky, R. J. & Welti, D. H., Nov 1 1994, In : Chemical Research in Toxicology. 7, 6, p. 784-791 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

The inhibitory effects of coffee on radical-mediated oxidation and mutagenicity

Stadler, R. H., Turesky, R. J., Müller, O., Markovic, J. & Leong-Morgenthaler, P. M., Jul 16 1994, In : Mutation Research Regular Papers. 308, 2, p. 177-190 14 p.

Research output: Contribution to journalArticle

98 Scopus citations
1993

Heterocyclic aromatic amine formation in grilled bacon, beef and fish and in grill scrapings

Gross, G. A., Turesky, R. J., Fay, L. B., Stillwell, W. G., Skipper, P. L. & Tannenbaum, S. R., Nov 1 1993, In : Carcinogenesis. 14, 11, p. 2313-2318 6 p.

Research output: Contribution to journalArticle

180 Scopus citations
12 Scopus citations

Phase I and phase II xenobiotic reactions and metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in aggregating liver cell cultures

Schilter, B., Turesky, R. J., Juillerat, M., Honegger, P. & Guigoz, Y., Mar 9 1993, In : Biochemical Pharmacology. 45, 5, p. 1087-1096 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
1992
157 Scopus citations
8 Scopus citations