1983 …2024

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2020

Development of a DNA Adductome Mass Spectral Database

Guo, J., Turesky, R. J., Tarifa, A., Decaprio, A. P., Cooke, M. S., Walmsley, S. J. & Villalta, P. W., Apr 20 2020, In : Chemical research in toxicology. 33, 4, p. 852-854 3 p.

Research output: Contribution to journalArticle

Kinetics of DNA Adducts and Abasic Site Formation in Tissues of Mice Treated with a Nitrogen Mustard

Chen, H., Cui, Z., Hejazi, L., Yao, L., Walmsley, S. J., Rizzo, C. J. & Turesky, R. J., Apr 20 2020, In : Chemical research in toxicology. 33, 4, p. 988-998 11 p.

Research output: Contribution to journalArticle

Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity

Lawana, V., Um, S. Y., Rochet, J. C., Turesky, R. J., Shannahan, J. H. & Cannon, J. R., Jan 1 2020, In : Toxicological Sciences. 173, 1, p. 171-188 18 p.

Research output: Contribution to journalArticle

2019

Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells

Bellamri, M., Yao, L., Bonala, R., Johnson, F., von Weymarn, L. B. & Turesky, R., Jul 1 2019, In : Archives of Toxicology. 93, 7, p. 1893-1902 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Quantitation of Apurinic/Apyrimidinic Sites in Isolated DNA and in Mammalian Tissue with a Reduced Level of Artifacts

Chen, H., Yao, L., Brown, C., Rizzo, C. J. & Turesky, R. J., Jun 4 2019, In : Analytical chemistry. 91, 11, p. 7403-7410 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations
2018

Biomonitoring an albumin adduct of the cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine in humans

Bellamri, M., Wang, Y., Yonemori, K., White, K. K., Wilkens, L. R., Le Marchand, L. & Turesky, R. J., Dec 31 2018, In : Carcinogenesis. 39, 12, p. 1455-1462 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access
5 Scopus citations
Open Access
6 Scopus citations

Method for Biomonitoring DNA Adducts in Exfoliated Urinary Cells by Mass Spectrometry

Yun, B. H., Bellamri, M., Rosenquist, T. A. & Turesky, R. J., Aug 21 2018, In : Analytical chemistry. 90, 16, p. 9943-9950 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

Springer, S. U., Chen, C. H., Del Carmen Rodriguez Pena, M., Li, L., Douville, C., Wang, Y., Cohen, J. D., Taheri, D., Silliman, N., Schaefer, J., Ptak, J., Dobbyn, L., Papoli, M., Kinde, I., Afsari, B., Tregnago, A. C., Bezerra, S. M., Vandenbussche, C., Fujita, K., Ertoy, D. & 20 others, Cunha, I. W., Yu, L., Bivalacqua, T. J., Grollman, A. P., Diaz, L. A., Karchin, R., Danilova, L., Huang, C. Y., Shun, C. T., Turesky, R. J., Yun, B. H., Rosenquist, T. A., Pu, Y. S., Hruban, R. H., Tomasetti, C., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Dickman, K. G. & Netto, G. J., Mar 20 2018, In : eLife. 7, e32143.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
9 Scopus citations
2017

A Rapid Throughput Method to Extract DNA from Formalin-Fixed Paraffin-Embedded Tissues for Biomonitoring Carcinogenic DNA Adducts

Yun, B. H., Xiao, S., Yao, L., Krishnamachari, S., Rosenquist, T. A., Dickman, K. G., Grollman, A. P., Murugan, P., Weight, C. J. & Turesky, R. J., Dec 18 2017, In : Chemical research in toxicology. 30, 12, p. 2130-2139 10 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Data-Independent Mass Spectrometry Approach for Screening and Identification of DNA Adducts

Guo, J., Villalta, P. W. & Turesky, R. J., Nov 7 2017, In : Analytical chemistry. 89, 21, p. 11728-11736 9 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and Albumin in Humans

Wang, Y., Villalta, P. W., Peng, L., Dingley, K., Malfatti, M. A., Turteltaub, K. W. & Turesky, R. J., Feb 20 2017, In : Chemical research in toxicology. 30, 2, p. 705-714 10 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes

Bellamri, M., Le Hegarat, L., Turesky, R. J. & Langouët, S., Feb 20 2017, In : Chemical research in toxicology. 30, 2, p. 657-668 12 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
Open Access
6 Scopus citations
2016

Aristolochic acid exposure in Romania and implications for renal cell carcinoma

Turesky, R. J., Yun, B. H., Brennan, P., Mates, D., Jinga, V., Harnden, P., Banks, R. E., Blanche, H., Bihoreau, M. T., Chopard, P., Letourneau, L., Lathrop, G. M. & Scelo, G., Jan 12 2016, In : British Journal of Cancer. 114, 1, p. 76-80 5 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Aristolochic acid in the etiology of renal cell carcinoma

Hoang, M. L., Chen, C. H., Chen, P. C., Roberts, N. J., Dickman, K. G., Yun, B. H., Turesky, R. J., Pu, Y. S., Vogelstein, B., Papadopoulos, N., Grollman, A. P., Kinzler, K. W. & Rosenquist, T. A., Dec 1 2016, In : Cancer Epidemiology Biomarkers and Prevention. 25, 12, p. 1600-1608 9 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Bioactivation of Heterocyclic Aromatic Amines by UDP Glucuronosyltransferases

Cai, T., Yao, L. & Turesky, R. J., May 16 2016, In : Chemical research in toxicology. 29, 5, p. 879-891 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
26 Scopus citations
17 Scopus citations

Dose validation of PhIP hair level as a biomarker of heterocyclic aromatic amines exposure: A feeding study

Le Marchand, L., Yonemori, K., White, K. K., Franke, A. A., Wilkens, L. R. & Turesky, R. J., Jul 1 2016, In : Carcinogenesis. 37, 7, p. 685-691 7 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Human biomonitoring of DNA adducts by ion trap multistage mass spectrometry

Guo, J. & Turesky, R. J., Jan 1 2016, In : Current protocols in nucleic acid chemistry. 2016, p. 7.24.1-7.24.25

Research output: Contribution to journalArticle

7 Scopus citations

Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts

Bellamri, M., Le Hegarat, L., Vernhet, L., Baffet, G., Turesky, R. J. & Langouët, S., Dec 1 2016, In : Environmental and Molecular Mutagenesis. 57, 9, p. 656-667 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Methemoglobin Formation and Characterization of Hemoglobin Adducts of Carcinogenic Aromatic Amines and Heterocyclic Aromatic Amines

Pathak, K. V., Chiu, T. L., Amin, E. A. & Turesky, R. J., Mar 21 2016, In : Chemical research in toxicology. 29, 3, p. 255-269 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Multiclass Carcinogenic DNA Adduct Quantification in Formalin-Fixed Paraffin-Embedded Tissues by Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry

Guo, J., Yun, B. H., Upadhyaya, P., Yao, L., Krishnamachari, S., Rosenquist, T. A., Grollman, A. P. & Turesky, R. J., May 3 2016, In : Analytical chemistry. 88, 9, p. 4780-4787 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Novel Transgenic Mouse Model for Studying Human Serum Albumin as a Biomarker of Carcinogenic Exposure

Sheng, J., Wang, Y., Turesky, R. J., Kluetzman, K., Zhang, Q. Y. & Ding, X., May 16 2016, In : Chemical research in toxicology. 29, 5, p. 797-809 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

2-Amino-9H-pyrido[2,3-b]indole (AαC) adducts and thiol oxidation of serum albumin as potential biomarkers of tobacco smoke

Pathak, K. V., Bellamri, M., Wang, Y., Langouët, S. & Turesky, R. J., Jun 26 2015, In : Journal of Biological Chemistry. 290, 26, p. 16304-16318 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Caffeine Cytochrome P450 1A2 Metabolic Phenotype Does Not Predict the Metabolism of Heterocyclic Aromatic Amines in Humans

Turesky, R. J., White, K. K., Wilkens, L. R. & Le Marchand, L., Aug 17 2015, In : Chemical research in toxicology. 28, 8, p. 1603-1615 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Characterization of Nitrogen Mustard Formamidopyrimidine Adduct Formation of Bis(2-chloroethyl)ethylamine with Calf Thymus DNA and a Human Mammary Cancer Cell Line

Gruppi, F., Hejazi, L., Christov, P. P., Krishnamachari, S., Turesky, R. J. & Rizzo, C. J., Aug 19 2015, In : Chemical research in toxicology. 28, 9, p. 1850-1860 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effect of Cytochrome P450 Reductase Deficiency on 2-Amino-9H-pyrido[2,3-b]indole Metabolism and DNA Adduct Formation in Liver and Extrahepatic Tissues of Mice

Turesky, R. J., Konorev, D., Fan, X., Tang, Y., Yao, L., Ding, X., Xie, F., Zhu, Y. & Zhang, Q. Y., Dec 21 2015, In : Chemical research in toxicology. 28, 12, p. 2400-2410 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
13 Scopus citations
11 Scopus citations
8 Scopus citations

New approaches for biomonitoring exposure to the human carcinogen aristolochic acid

Yun, B. H., Sidorenko, V. S., Rosenquist, T. A., Dickman, K. G., Grollman, A. P. & Turesky, R. J., Jul 1 2015, In : Toxicology Research. 4, 4, p. 763-776 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Simultaneous detection of multiple DNA adducts in human lung samples by isotope-dilution UPLC-MS/MS

Monien, B. H., Schumacher, F., Herrmann, K., Glatt, H., Turesky, R. J. & Chesné, C., Jan 6 2015, In : Analytical chemistry. 87, 1, p. 641-648 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2014

Formalin-fixed paraffin-embedded tissue as a source for quantitation of carcinogen DNA adducts: Aristolochic acid as a prototype carcinogen

Yun, B. H., Yao, L., Jelaković, B., Nikolić, J., Dickman, K. G., Grollman, A. P., Rosenquist, T. A. & Turesky, R. J., Sep 2014, In : Carcinogenesis. 35, 9, p. 2055-2061 7 p., bgu101.

Research output: Contribution to journalArticle

13 Scopus citations
10 Scopus citations
2013

Biomonitoring the cooked meat carcinogen 2-Amino-1- Methyl-6- Phenylimidazo[4,5-b]Pyridine in hair: Impact of exposure, hair pigmentation, and cytochrome P450 1A2 phenotype

Turesky, R. J., Liu, L., Gu, D., Yonemori, K. M., White, K. K., Wilkens, L. R. & Marchand, L. L., Mar 1 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 3, p. 356-364 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Capturing labile sulfenamide and sulfinamide serum albumin adducts of carcinogenic arylamines by chemical oxidation

Peng, L. & Turesky, R. J., Jan 15 2013, In : Analytical chemistry. 85, 2, p. 1065-1072 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
11 Scopus citations
17 Scopus citations

Human formalin-fixed paraffin-embedded tissues: An untapped specimen for biomonitoring of carcinogen DNA adducts by mass spectrometry

Yun, B. H., Rosenquist, T. A., Nikolić, J., Dragičević, D., Tomić, K., Jelaković, B., Dickman, K. G., Grollman, A. P. & Turesky, R. J., May 7 2013, In : Analytical chemistry. 85, 9, p. 4251-4258 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing

Hoang, M. L., Chen, C. H., Sidorenko, V. S., He, J., Dickman, K. G., Yun, B. H., Moriya, M., Niknafs, N., Douville, C., Karchin, R., Turesky, R. J., Pu, Y. S., Vogelstein, B., Papadopoulos, N., Grollman, A. P., Kinzler, K. W. & Rosenquist, T. A., Aug 7 2013, In : Science Translational Medicine. 5, 197, 197ra102.

Research output: Contribution to journalArticle

138 Scopus citations
2012

Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid

Jelaković, B., Karanović, S., Vuković-Lela, I., Miller, F., Edwards, K. L., Nikolić, J., Tomić, K., Slade, N., Brdar, B., Turesky, R. J., Stipancić, Ž., Dittrich, D., Grollman, A. P. & Dickman, K. G., Mar 2 2012, In : Kidney international. 81, 6, p. 559-567 9 p.

Research output: Contribution to journalArticle

123 Scopus citations

Aristolochic acid-associated urothelial cancer in Taiwan

Chen, C. H., Dickman, K. G., Moriya, M., Zavadil, J., Sidorenko, V. S., Edwards, K. L., Gnatenko, D. V., Wu, L., Turesky, R. J., Wu, X. R., Pu, Y. S. & Grollman, A. P., May 22 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 21, p. 8241-8246 6 p.

Research output: Contribution to journalArticle

234 Scopus citations

Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry

Yun, B. H., Rosenquist, T. A., Sidorenko, V., Iden, C. R., Chen, C. H., Pu, Y. S., Bonala, R., Johnson, F., Dickman, K. G., Grollman, A. P. & Turesky, R. J., May 21 2012, In : Chemical research in toxicology. 25, 5, p. 1119-1131 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

Biomonitoring the cooked meat carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b ]pyridine in canine fur

Gu, D., Neuman, Z. L., Modiano, J. F. & Turesky, R. J., Sep 12 2012, In : Journal of agricultural and food chemistry. 60, 36, p. 9371-9375 5 p.

Research output: Contribution to journalArticle

8 Scopus citations