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Research Output 1983 2019

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Article
2008
96 Citations (Scopus)

Functional tissue-engineered valves from cell-remodeled fibrin with commissural alignment of cell-produced collagen

Robinson, P. S., Johnson, S. L., Evans, M. C., Barocas, V. H. & Tranquillo, R. T., Jan 1 2008, In : Tissue Engineering - Part A.. 14, 1, p. 83-95 13 p.

Research output: Contribution to journalArticle

Fibrin
Collagen
Gels
Tissue
Fungi
2006
203 Citations (Scopus)

Advanced tools for tissue engineering: Scaffolds, bioreactors, and signaling

Freed, L. E., Guilak, F., Guo, X. E., Gray, M. L., Tranquillo, R. T., Holmes, J. W., Radisic, M., Sefton, M. V., Kaplan, D. & Vunjak-Novakovic, G., Dec 1 2006, In : Tissue Engineering. 12, 12, p. 3285-3305 21 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Bioreactors
Tissue engineering
Tissue
Cartilage
48 Citations (Scopus)

Cell sourcing and culture conditions for fibrin-based valve constructs

Williams, C., Johnson, S. L., Robinson, P. S. & Tranquillo, R. T., Jun 1 2006, In : Tissue Engineering. 12, 6, p. 1489-1502 14 p.

Research output: Contribution to journalArticle

Fibroblasts
Fibrin
Eagles
Cell Culture Techniques
Collagen
141 Citations (Scopus)

Cytokine-induced differentiation of multipotent adult progenitor cells into functional smooth muscle cells

Ross, J. J., Hong, Z., Willenbring, B., Zeng, L., Isenberg, B., Eu, H. L., Reyes, M., Keirstead, S. A., Weir, E. K., Tranquillo, R. T. & Verfaillie, C. M., Dec 1 2006, In : Journal of Clinical Investigation. 116, 12, p. 3139-3149 11 p.

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Stem Cells
Cytokines
Smooth Muscle
Serotonin Receptor Agonists
1 Citation (Scopus)

Education for careers in tissue engineering and regenerative medicine

Griffith, L., Swartz, M. & Tranquillo, R. T., Feb 1 2006, In : Annals of Biomedical Engineering. 34, 2, p. 265-269 5 p.

Research output: Contribution to journalArticle

Tissue engineering
Education
Physiological models
Tissue
Regenerative Medicine
61 Citations (Scopus)

Endothelialization and flow conditioning of fibrin-based media-equivalents

Isenberg, B. C., Williams, C. & Tranquillo, R. T., Jun 1 2006, In : Annals of Biomedical Engineering. 34, 6, p. 971-985 15 p.

Research output: Contribution to journalArticle

Endothelial cells
Shear stress
Bond strength (materials)
Cell adhesion
Bioreactors
78 Citations (Scopus)

Tissue-engineered valves with commissural alignment

Neidert, M. R. & Tranquillo, R. T., Apr 1 2006, In : Tissue Engineering. 12, 4, p. 891-903 13 p.

Research output: Contribution to journalArticle

Collagen
Tissue
Fibroblasts
Gels
Histology
2005
23 Citations (Scopus)
Transforming Growth Factor beta1
Schwann Cells
Collagen
Gels
Cues
2004
26 Citations (Scopus)

Cryopreservation of Collagen-Based Tissue Equivalents. II. Improved Freezing in the Presence of Cryoprotective Agents

Neidert, M. R., Devireddy, R. V., Tranquillo, R. T. & Bischof, J. C., Jan 1 2004, In : Tissue Engineering. 10, 1-2, p. 23-32 10 p.

Research output: Contribution to journalArticle

Collagen
Freezing
Tissue
Opacity
Mechanical properties
2003
154 Citations (Scopus)

A fibrin-based arterial media equivalent

Grassl, E. D., Oegema, T. R. & Tranquillo, R. T., Sep 1 2003, In : Journal of Biomedical Materials Research - Part A. 66, 3, p. 550-561 12 p.

Research output: Contribution to journalArticle

Fibrin
Collagen
Insulin
Tensile strength
Elastic moduli
28 Citations (Scopus)

Cryopreservation of Collagen-Based Tissue Equivalents. I. Effect of Freezing in the Absence of Cryoprotective Agents

Devireddy, R. V., Neidert, M. R., Bischof, J. C. & Tranquillo, R. T., Dec 1 2003, In : Tissue Engineering. 9, 6, p. 1089-1100 12 p.

Research output: Contribution to journalArticle

Collagen
Freezing
Tissue
Mechanical properties
Cells
94 Citations (Scopus)

ECM gene expression correlates with in vitro tissue growth and development in fibrin gel remodeled by neonatal smooth muscle cells

Ross, J. J. & Tranquillo, R. T., Jan 1 2003, In : Matrix Biology. 22, 6, p. 477-490 14 p.

Research output: Contribution to journalArticle

Fibrin
Growth and Development
Smooth Muscle Myocytes
Collagen
Tropoelastin
201 Citations (Scopus)

Elastic fiber production in cardiovascular tissue-equivalents

Long, J. L. & Tranquillo, R. T., Jan 1 2003, In : Matrix Biology. 22, 4, p. 339-350 12 p.

Research output: Contribution to journalArticle

Elastic Tissue
Fibrin
Smooth Muscle Myocytes
Elastin
Aminopropionitrile
151 Citations (Scopus)

Long-term cyclic distention enhances the mechanical properties of collagen-based media-equivalents

Isenberg, B. C. & Tranquillo, R. T., Sep 11 2003, In : Annals of Biomedical Engineering. 31, 8, p. 937-949 13 p.

Research output: Contribution to journalArticle

Collagen
Elastin
Mechanical properties
Relaxation time
Muscle
43 Citations (Scopus)

Rational Design of Contact Guiding, Neurotrophic Matrices for Peripheral Nerve Regeneration

Rosner, B. I., Siegel, R. A., Grosberg, A. & Tranquillo, R. T., Dec 1 2003, In : Annals of Biomedical Engineering. 31, 11, p. 1383-1401 19 p.

Research output: Contribution to journalArticle

Microspheres
Gels
Collagen
Membranes
Intercellular Signaling Peptides and Proteins
86 Citations (Scopus)

Temporal variations in cell migration and traction during fibroblast-mediated gel compaction

Shreiber, D. I., Barocas, V. H. & Tranquillo, R. T., Jun 1 2003, In : Biophysical journal. 84, 6, p. 4102-4114 13 p.

Research output: Contribution to journalArticle

Traction
Cell Movement
Fibroblasts
Gels
Foreskin
2002
17 Citations (Scopus)

A novel implantable collagen gel assay for fibroblast traction and proliferation during wound healing

Enever, P. A. J., Shreiber, D. I. & Tranquillo, R. T., Jan 1 2002, In : Journal of Surgical Research. 105, 2, p. 160-172 13 p.

Research output: Contribution to journalArticle

Traction
Wound Healing
Collagen
Fibroblasts
Gels
61 Citations (Scopus)
Collagen
Compaction
Tissue
Birefringence
Polystyrenes
Collagen
Scaffolds
Tissue
Scaffolds (biology)
Elastin
127 Citations (Scopus)

Enhanced fibrin remodeling in vitro with TGF-β1, insulin and plasmin for improved tissue-equivalents

Neidert, M. R., Lee, E. S., Oegema, T. R. & Tranquillo, R. T., Jun 24 2002, In : Biomaterials. 23, 17, p. 3717-3731 15 p.

Research output: Contribution to journalArticle

Fibrinolysin
Insulin
Fibrin
Tissue
Tensile Strength
160 Citations (Scopus)

Fiber alignment imaging during mechanical testing of soft tissues

Tower, T. T., Neidert, M. R. & Tranquillo, R. T., Dec 1 2002, In : Annals of Biomedical Engineering. 30, 10, p. 1221-1233 13 p.

Research output: Contribution to journalArticle

Mechanical testing
Tissue
Imaging techniques
Fibers
Mechanical properties
172 Citations (Scopus)

Fibrin as an alternative biopolymer to type-I collagen for the fabrication of a media equivalent

Grassl, E. D., Oegema, T. R. & Tranquillo, R. T., Jun 15 2002, In : Journal of Biomedical Materials Research. 60, 4, p. 607-612 6 p.

Research output: Contribution to journalArticle

Biopolymers
Collagen Type I
Fibrin
Collagen
Fabrication
21 Citations (Scopus)

Macrophages influence a competition of contact guidance and chemotaxis for fibroblast alignment in a fibrin gel coculture assay

Bromberek, B. A., Enever, P. A. J., Shreiber, D. I., Caldwell, M. D. & Tranquillo, R. T., Jan 1 2002, In : Experimental Cell Research. 275, 2, p. 230-242 13 p.

Research output: Contribution to journalArticle

Chemotaxis
Coculture Techniques
Fibrin
Fibroblasts
Gels
42 Citations (Scopus)

The tissue-engineered small-diameter artery

Tranquillo, R. T., Jan 1 2002, In : Annals of the New York Academy of Sciences. 961, p. 251-254 4 p.

Research output: Contribution to journalArticle

Stem Cells
Tissue Engineering
4 Citations (Scopus)

Vascular assembly in engineered and natural tissues: Breakout session summary

Skalak, T. C., Little, C. D., McIntire, L. V., Hirschi, K. K., Tranquillo, R. T., Post, M. & Ranieri, J., Jan 1 2002, In : Annals of the New York Academy of Sciences. 961, p. 255-257 3 p.

Research output: Contribution to journalArticle

Summary
2001
74 Citations (Scopus)

Alignment maps of tissues: II. Fast harmonic analysis for imaging

Tower, T. T. & Tranquillo, R. T., Jan 1 2001, In : Biophysical journal. 81, 5, p. 2964-2971 8 p.

Research output: Contribution to journalArticle

Birefringence
Light
Heart Valves
Swine
Direction compound
86 Citations (Scopus)

Alignment maps of tissues: I. Microscopic elliptical polarimetry

Tower, T. T. & Tranquillo, R. T., Jan 1 2001, In : Biophysical journal. 81, 5, p. 2954-2963 10 p.

Research output: Contribution to journalArticle

Tunica Media
Birefringence
Light
59 Citations (Scopus)

Effects of PDGF-BB on rat dermal fibroblast behavior in mechanically stressed and unstressed collagen and fibrin gels

Shreiber, D. I., Enever, P. A. J. & Tranquillo, R. T., May 15 2001, In : Experimental Cell Research. 266, 1, p. 155-166 12 p.

Research output: Contribution to journalArticle

Inbred BB Rats
Fibrin
Collagen
Traction
Fibroblasts
Biopolymers
Collagen
Fabrication
Tissue engineering
Degradation

Fibroblast traction-migration relationships in collagen gels

Shreiber, D. I. & Tranquillo, R. T., Dec 1 2001, In : American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 50, p. 667-668 2 p.

Research output: Contribution to journalArticle

Fibroblasts
Collagen
Gels
Antibodies
Assays
124 Citations (Scopus)

Neuronal contact guidance in magnetically aligned fibrin gels: Effect of variation in gel mechano-structural properties

Dubey, N., Letourneau, P. C. & Tranquillo, R. T., Apr 2 2001, In : Biomaterials. 22, 10, p. 1065-1075 11 p.

Research output: Contribution to journalArticle

Fibrin
Structural properties
Gels
Spinal Ganglia
Neurites

Polarized light imaging during mechanical testing of tissue equivalents

Tower, T. T., Neidert, M. R. & Tranquillo, R. T., Dec 1 2001, In : American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 50, p. 411-412 2 p.

Research output: Contribution to journalArticle

Mechanical testing
Light polarization
Tissue
Imaging techniques
Testing
2000
7 Citations (Scopus)

A self-consistent cell flux expression for simultaneous chemotaxis and contact guidance in tissues

Wagle, M. A. & Tranquillo, R. T., Jan 1 2000, In : Journal of Mathematical Biology. 41, 4, p. 315-330 16 p.

Research output: Contribution to journalArticle

Chemotaxis
chemotaxis
Cues
Guidance
Contact
2 Citations (Scopus)

Determination of loading and unloading of cryoprotective agents in tissues and tissue-equivalents

Devireddy, R., Sankha, B., Neidert, M., Tranquillo, R. T. & Bischof, J. C., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Unloading
Tissue
Fick's laws
Freezing
Membranes

Fabrication of a tissue-equivalent cardiovascular valve

Neidert, M., Tower, T., Oegema, T. & Tranquillo, R. T., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Biopolymers
Tissue
Fabrication
Chemical analysis

Fibrin as an alternative biopolymer to type I collagen for TissueEquivalent fabrication

Grassl, E., Neidert, M., Oegema, T. & Tranquillo, R. T., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Biopolymers
Collagen
Military electronic countermeasures
Fabrication
Fibroblasts
122 Citations (Scopus)

Mechanisms of stiffening and strengthening in media-equivalents fabricated using glycation

Girton, T. S., Oegema, T. R., Grassl, E. D., Isenberg, B. C. & Tranquillo, R. T., Jun 1 2000, In : Journal of Biomechanical Engineering. 122, 3, p. 216-223 8 p.

Research output: Contribution to journalArticle

Tensile Strength
Collagen
Tensile strength
Aorta
Rats

Polarized light alignment imaging during mechanical testing of tissues

Tower, T., Neidert, M. & Tranquillo, R. T., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Mechanical testing
Light polarization
Pixels
Cameras
Tissue

Polarized light alignment imaging of tissue organization

Tower, T. & Tranquillo, R. T., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Light polarization
Tissue
Imaging techniques
Fibroblasts
Collagen

Strategies for enhancing the mechanical properties of media-equivalents

Isenberg, B., Grassl, E., Oegema, T. & Tranquillo, R. T., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Collagen
Mechanical properties
Compaction
Grafts
Rats
Fibroblasts
Platelets
Collagen
Gels
Assays

Temporal analysis of fibroblast traction and migration in tissue equivalents

Shreiber, D., Barocas, V. H., Enever, P., Wagle, M. & Tranquillo, R. T., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Fibroblasts
Tissue
Software packages
Compaction
Differential equations
1999
76 Citations (Scopus)

A fibrin or collagen gel assay for tissue cell chemotaxis: Assessment of fibroblast chemotaxis to GRGDSP

Knapp, D. M., Helou, E. F. & Tranquillo, R. T., Mar 15 1999, In : Experimental Cell Research. 247, 2, p. 543-553 11 p.

Research output: Contribution to journalArticle

glycyl-arginyl-glycyl-aspartyl-seryl-proline
Chemotaxis
Fibrin
Collagen
Fibroblasts
160 Citations (Scopus)

Exploiting glycation to stiffen and strengthen tissue equivalents for tissue engineering

Girton, T. S., Oegema, T. R. & Tranquillo, R. T., May 27 1999, In : Journal of Biomedical Materials Research. 46, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

Tissue engineering
Tissue
Ribose
Cell culture
Sugars
181 Citations (Scopus)

Guided neurite elongation and schwann cell invasion into magnetically aligned collagen in simulated peripheral nerve regeneration

Dubey, N., Letourneau, P. C. & Tranquillo, R. T., Jan 1 1999, In : Experimental Neurology. 158, 2, p. 338-350 13 p.

Research output: Contribution to journalArticle

Nerve Regeneration
Schwann Cells
Neurites
Peripheral Nerves
Collagen
214 Citations (Scopus)

Magnetically aligned collagen gel filling a collagen nerve guide improves peripheral nerve regeneration

Ceballos, D., Navarro, X., Dubey, N., Wendelschafer-Crabb, G., Kennedy, W. R. & Tranquillo, R. T., Jan 1 1999, In : Experimental Neurology. 158, 2, p. 290-300 11 p.

Research output: Contribution to journalArticle

Nerve Regeneration
Peripheral Nerves
Collagen
Gels
Regeneration
91 Citations (Scopus)

Self-organization of tissue-equivalents: The nature and role of contact guidance

Tranquillo, R. T., Dec 1 1999, In : Biochemical Society Symposium. 65, p. 27-42 16 p.

Research output: Contribution to journalArticle

Gels
Tissue
Compaction
Traction
Cell Movement
1998
133 Citations (Scopus)

Engineered alignment in media equivalents: Magnetic preaiignment and mandrel compaction

Barocas, V. H., Girton, T. S. & Tranquillo, R. T., Jan 1 1998, In : Journal of Biomechanical Engineering. 120, 5, p. 660-666 7 p.

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Muscle
Compaction
Collagen
Fabrication
1997
47 Citations (Scopus)
Traction
Mechanics
Collagen
Assays
Compaction