1983 …2024

Research output per year

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Research Output

2019

Tissue-engineered transcatheter vein valve

Syedain, Z. H., Jenson, A. C., Patel, P. S., Feagler, C., Bahmer, L., Faizer, R. & Tranquillo, R. T., Sep 2019, In : Biomaterials. 216, 119229.

Research output: Contribution to journalArticle

2018

A cardiac patch from aligned microvessel and cardiomyocyte patches

Schaefer, J. A., Guzman, P. A., Riemenschneider, S. B., Kamp, T. J. & Tranquillo, R. T., Feb 1 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 2, p. 546-556 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hemocompatible tissue-engineered vascular grafts using adult mesenchymal stem cells

La, A. & Tranquillo, R. T., Mar 2018, In : Current Opinion in Biomedical Engineering. 5, p. 66-73 8 p.

Research output: Contribution to journalReview article

4 Scopus citations

Shear Conditioning of Adipose Stem Cells for Reduced Platelet Binding to Engineered Vascular Grafts

La, A. & Tranquillo, R. T., Aug 2018, In : Tissue Engineering - Part A. 24, 15-16, p. 1242-1250 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

A completely biological "off-the-shelf" arteriovenous graft that recellularizes in baboons

Syedain, Z. H., Graham, M. L., Dunn, T. B., O'Brien, T., Johnson, S. L., Schumacher, R. J. & Tranquillo, R. T., Nov 1 2017, In : Science Translational Medicine. 9, 414, eaan4209.

Research output: Contribution to journalArticle

23 Scopus citations

Corrigendum: Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs

Syedain, Z., Reimer, J., Lahti, M., Berry, J., Johnson, S., Bianco, R. & Tranquillo, R. T., Jan 17 2017, In : Nature communications. 8, 1 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Implantation of a Tissue-Engineered Tubular Heart Valve in Growing Lambs

Reimer, J., Syedain, Z., Haynie, B., Lahti, M., Berry, J. & Tranquillo, R., Feb 1 2017, In : Annals of Biomedical Engineering. 45, 2, p. 439-451 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
2016

Cells for tissue engineering of cardiac valves

Jana, S., Tranquillo, R. T. & Lerman, A., Oct 1 2016, In : Journal of Tissue Engineering and Regenerative Medicine. 10, 10, p. 804-824 21 p.

Research output: Contribution to journalReview article

30 Scopus citations

Cyclic Stretch and Perfusion Bioreactor for Conditioning Large Diameter Engineered Tissue Tubes

Schmidt, J. B. & Tranquillo, R. T., May 1 2016, In : Annals of Biomedical Engineering. 44, 5, p. 1785-1797 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of Intermittent and Incremental Cyclic Stretch on ERK Signaling and Collagen Production in Engineered Tissue

Schmidt, J. B., Chen, K. & Tranquillo, R. T., Mar 1 2016, In : Cellular and Molecular Bioengineering. 9, 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Inosculation and perfusion of pre-vascularized tissue patches containing aligned human microvessels after myocardial infarction

Riemenschneider, S. B., Mattia, D. J., Wendel, J. S., Schaefer, J. A., Ye, L., Guzman, P. A. & Tranquillo, R. T., Aug 1 2016, In : Biomaterials. 97, p. 51-61 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Swelling of Collagen-Hyaluronic Acid Co-Gels: An In Vitro Residual Stress Model

Lai, V. K., Nedrelow, D. S., Lake, S. P., Kim, B., Weiss, E. M., Tranquillo, R. T. & Barocas, V. H., Oct 1 2016, In : Annals of Biomedical Engineering. 44, 10, p. 2984-2993 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Tissue Contraction Force Microscopy for Optimization of Engineered Cardiac Tissue

Schaefer, J. A. & Tranquillo, R. T., Jan 2016, In : Tissue Engineering - Part C: Methods. 22, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs

Syedain, Z. H., Reimer, J., Lahti, M., Berry, J., Johnson, S. & Tranquillo, R. T., Sep 27 2016, In : Nature communications. 7, 12951.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations
2015

6-Month aortic valve implantation of an off-the-shelf tissue-engineered valve in sheep

Syedain, Z., Reimer, J., Schmidt, J., Lahti, M., Berry, J., Bianco, R. & Tranquillo, R. T., Dec 2015, In : Biomaterials. 73, p. 175-184 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

A mathematical model for understanding fluid flow through engineered tissues containing microvessels

Morin, K. T., Lenz, M. S., Labat, C. A. & Tranquillo, R. T., May 1 2015, In : Journal of biomechanical engineering. 137, 5, 051003.

Research output: Contribution to journalArticle

1 Scopus citations

Automated image analysis programs for the quantification of microvascular network characteristics

Morin, K. T., Carlson, P. D. & Tranquillo, R. T., Aug 1 2015, In : Methods. 84, p. 76-83 8 p.

Research output: Contribution to journalReview article

9 Scopus citations

Cardiac tissue engineering for the treatment of heart failure post-infarction

Wendel, J. S. & Tranquillo, R. T., Jan 1 2015, Cardiac Fibrosis and Heart Failure: Cause or Effect?. Springer International Publishing, p. 405-418 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Emerging Trends in Heart Valve Engineering: Part I. Solutions for Future

Kheradvar, A., Groves, E. M., Dasi, L. P., Alavi, S. H., Tranquillo, R., Grande-Allen, K. J., Simmons, C. A., Griffith, B., Falahatpisheh, A., Goergen, C. J., Mofrad, M. R. K., Baaijens, F., Little, S. H. & Canic, S., Apr 1 2015, In : Annals of Biomedical Engineering. 43, 4, p. 833-843 11 p.

Research output: Contribution to journalReview article

47 Scopus citations

Emerging Trends in Heart Valve Engineering: Part IV. Computational Modeling and Experimental Studies

Kheradvar, A., Groves, E. M., Falahatpisheh, A., Mofrad, M. K., Hamed Alavi, S., Tranquillo, R., Dasi, L. P., Simmons, C. A., Jane Grande-Allen, K., Goergen, C. J., Baaijens, F., Little, S. H., Canic, S. & Griffith, B., Oct 22 2015, In : Annals of Biomedical Engineering. 43, 10, p. 2314-2333 20 p.

Research output: Contribution to journalReview article

24 Scopus citations

Emerging Trends in Heart Valve Engineering: Part II. Novel and Standard Technologies for Aortic Valve Replacement

Kheradvar, A., Groves, E. M., Goergen, C. J., Alavi, S. H., Tranquillo, R., Simmons, C. A., Dasi, L. P., Grande-Allen, K. J., Mofrad, M. R. K., Falahatpisheh, A., Griffith, B., Baaijens, F., Little, S. H. & Canic, S., Apr 1 2015, In : Annals of Biomedical Engineering. 43, 4, p. 844-857 14 p.

Research output: Contribution to journalReview article

19 Scopus citations

Emerging Trends in Heart Valve Engineering: Part III. Novel Technologies for Mitral Valve Repair and Replacement

Kheradvar, A., Groves, E. M., Simmons, C. A., Griffith, B., Alavi, S. H., Tranquillo, R., Dasi, L. P., Falahatpisheh, A., Grande-Allen, K. J., Goergen, C. J., Mofrad, M. R. K., Baaijens, F., Canic, S. & Little, S. H., Apr 1 2015, In : Annals of Biomedical Engineering. 43, 4, p. 858-870 13 p.

Research output: Contribution to journalReview article

19 Scopus citations

Functional effects of a tissue-engineered cardiac patch from human induced pluripotent stem cell-derived cardiomyocytes in a rat infarct model

Wendel, J. S., Ye, L., Tao, R., Zhang, J., Zhang, J., Kamp, T. J. & Tranquillo, R. T., Nov 2015, In : Stem Cells Translational Medicine. 4, 11, p. 1324-1332 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Hydrogel scaffolds for regenerative medicine

Sander, E. A., Grassl, E. D. & Tranquillo, R. T., Jan 1 2015, Biomaterials and Regenerative Medicine. Cambridge University Press, p. 295-316 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Influence of culture conditions and extracellular matrix alignment on human mesenchymal stem cells invasion into decellularized engineered tissues

Weidenhamer, N. K., Moore, D. L., Lobo, F. L., Klair, N. T. & Tranquillo, R. T., May 1 2015, In : Journal of Tissue Engineering and Regenerative Medicine. 9, 5, p. 605-618 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Pediatric tubular pulmonary heart valve from decellularized engineered tissue tubes

Reimer, J. M., Syedain, Z. H., Haynie, B. H. T. & Tranquillo, R. T., Sep 1 2015, In : Biomaterials. 62, p. 88-94 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Blood outgrowth endothelial cells alter remodeling of completely biological engineered grafts implanted into the sheep femoral artery

Meier, L. A., Syedain, Z. H., Lahti, M. T., Johnson, S. S., Chen, M. H., Hebbel, R. P. & Tranquillo, R. T., Mar 2014, In : Journal of cardiovascular translational research. 7, 2, p. 242-249 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Engineered microvessels with strong alignment and high lumen density via cell-induced fibrin gel compaction and interstitial flow

Morin, K. T., Dries-Devlin, J. L. & Tranquillo, R. T., Feb 1 2014, In : Tissue Engineering - Part A. 20, 3-4, p. 553-565 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Functional consequences of a tissue-engineered myocardial patch for cardiac repair in a rat infarct model

Wendel, J. S., Ye, L., Zhang, P., Tranquillo, R. T. & Zhang, J. J., Apr 1 2014, In : Tissue Engineering - Part A. 20, 7-8, p. 1325-1335 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Implantation of completely biological engineered grafts following decellularization into the sheep femoral artery

Syedain, Z. H., Meier, L. A., Lahti, M. T., Johnson, S. L. & Tranquillo, R. T., Jun 1 2014, In : Tissue Engineering - Part A. 20, 11-12, p. 1726-1734 9 p.

Research output: Contribution to journalArticle

66 Scopus citations
2013

Aligned human microvessels formed in 3D fibrin gel by constraint of gel contraction

Morin, K. T., Smith, A. O., Davis, G. E. & Tranquillo, R. T., Nov 1 2013, In : Microvascular Research. 90, p. 12-22 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
18 Scopus citations

A multiscale approach to modeling the passive mechanical contribution of cells in tissues

Lai, V., Hadi, M. F., Tranquillo, R. T. & Barocas, V. H., Dec 1 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. (ASME 2013 Summer Bioengineering Conference, SBC 2013; vol. 1 B).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Combating adaptation to cyclic stretching by prolonging activation of extracellular signal-regulated kinase

Weinbaum, J. S., Schmidt, J. B. & Tranquillo, R. T., Sep 1 2013, In : Cellular and Molecular Bioengineering. 6, 3, p. 279-286 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Decellularized tissue-engineered heart valve leaflets with recellularization potential

Syedain, Z. H., Bradee, A. R., Kren, S., Taylor, D. A. & Tranquillo, R. T., Mar 1 2013, In : Tissue Engineering - Part A. 19, 5-6, p. 759-769 11 p.

Research output: Contribution to journalArticle

64 Scopus citations

Engineered microvessels subjected to interstitial flow

Morin, K. T., Dries-Devlin, J. L. & Tranquillo, R. T., Dec 1 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. (ASME 2013 Summer Bioengineering Conference, SBC 2013; vol. 1 A).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

35 Scopus citations

In vitro models of angiogenesis and vasculogenesis in fibrin gel

Morin, K. T. & Tranquillo, R. T., Oct 1 2013, In : Experimental Cell Research. 319, 16, p. 2409-2417 9 p.

Research output: Contribution to journalReview article

67 Scopus citations

Novel tissue-engineered heart valve

Syedain, Z., Meier, L., Reimer, J. & Tranquillo, R., Dec 1 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. (ASME 2013 Summer Bioengineering Conference, SBC 2013; vol. 1 A).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Swelling of collagen-hyaluronic acid tissue-equivalents: An experimental model to evaluate residual stress in soft tissues

Lai, V., Lake, S. P., Kim, B., Weiss, E. M., Tranquillo, R. T. & Barocas, V. H., Dec 1 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. Vol. 1 B.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tissue-engineered heart valves

Schmidt, J. B. & Tranquillo, R. T., Jan 1 2013, Heart Valves: From Design to Clinical Implantation. Springer US, p. 261-280 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Tubular heart valves from decellularized engineered tissue

Syedain, Z. H., Meier, L. A., Reimer, J. M. & Tranquillo, R. T., Jul 30 2013, In : Annals of Biomedical Engineering. 41, 12, p. 2645-2654 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Collagen network architecture varies between pure collagen and collagen-fibrin co-gels

Lai, V., Kerandi, A. M., Lake, S. P., Tranquillo, R. T. & Barocas, V. H., Dec 1 2012, ASME 2012 Summer Bioengineering Conference, SBC 2012. p. 1219-1220 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hypoxic culture and insulin yield improvements to fibrin-based engineered tissue

Bjork, J. W., Meier, L. A., Johnson, S. L., Syedain, Z. H. & Tranquillo, R. T., Apr 1 2012, In : Tissue Engineering - Part A. 18, 7-8, p. 785-795 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
54 Scopus citations

Microstructural and mechanical differences between digested collagen-fibrin co-gels and pure collagen and fibrin gels

Lai, V. K., Frey, C. R., Kerandi, A. M., Lake, S. P., Tranquillo, R. T. & Barocas, V. H., Nov 2012, In : Acta Biomaterialia. 8, 11, p. 4031-4042 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Reply to the Letter to the Editor

Tranquillo, R. T. & Dickinson, R. B., Dec 1 2012, In : AICHE Journal. 58, 12, p. 3931-3932 2 p.

Research output: Contribution to journalLetter

2011

(336d) decellularization of tissue engineered leaflets with adult stem cell recellularization

Syedain, Z., Bradee, A. & Tranquillo, R. T., Jan 1 2011, Food, Pharmaceutical and Bioengineering Division - Core Programming Topic at the 2011 AIChE Annual Meeting. AIChE, p. 326-327 2 p. (Food, Pharmaceutical and Bioengineering Division - Core Programming Topic at the 2011 AIChE Annual Meeting; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Collagen network topology is influenced by collagen concentration, but not by co-gelation with fibrin

Lai, V., Sander, E. A., Lake, S. P., Tranquillo, R. T. & Barocas, V. H., Dec 1 2011, ASME 2011 Summer Bioengineering Conference, SBC 2011. PARTS A AND B ed. p. 1187-1188 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Engineering of Small-Diameter Vessels

Isenberg, B. C., Williams, C. & Tranquillo, R. T., Dec 1 2011, Principles of Regenerative Medicine. Elsevier Inc., p. 853-875 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations