Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
DSc, Biochemistry, Queens' University of Belfast, UK
Award Date: Jul 1 1999
PhD, Biochemistry, Queens' University of Belfast, UK
Award Date: Jul 1 1986
MS, Biochemistry, Queens' University of Belfast, UK
Award Date: Dec 16 1982
BS, Biological Sciences, Ulster University
Award Date: Jul 1 1980
Research Interest Keywords
- Breast cancer
- drug resistance
- systems biology
- hormone receptors
- signaling
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Collaborations and top research areas from the last five years
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Novel functions of ESRRB in glioblastoma
Clarke, R. R. (PI) & Jin, L. (CoI)
GEORGETOWN UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
2/8/24 → 1/31/26
Project: Research project
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CryoEM Support Technology
Clarke, R. R. (PI)
USDOC NATL INST OF STANDARDS AND TECH (N
9/1/23 → 8/31/26
Project: Research project
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Cell communication in antiestrogen resistance
Clarke, R. R. (PI) & Sengupta, S. (CoI)
4/1/21 → 9/14/23
Project: Research project
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Development of a Cancer Immune Therapy Paradigm with Iron Oxide Nanoparticles
Clarke, R. R. (PI) & Jin, L. (CoI)
JOHNS HOPKINS UNIVERSITY, THE JAYNE KOSKINAS TED GIOVANIS
7/16/20 → 4/30/23
Project: Research project
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Integrative analysis of exitrons in metastatic prostate cancer
Clarke, R. R. (PI), Dehm, S. M. (CoI) & Yang, R. (Prior Principal Investigator)
9/15/19 → 7/14/24
Project: Research project
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Bayesian identification of differentially expressed isoforms using a novel joint model of RNA-seq data
Shi, X., Wang, X., Jin, L., Halakivi-Clarke, L., Clarke, R., Neuwald, A. F. & Xuan, J., Jan 2025, In: PLoS computational biology. 21, 1, e1012750.Research output: Contribution to journal › Article › peer-review
Open Access -
BLID is a drug-responsive target of FOXO3a and multi-omics analysis reveals survival mechanisms and therapeutic vulnerabilities in BLID-deficient breast cancer cells
Yadavalli, S., Hu, R., Rait, A., Varghese, R., Li, J., Eidelman, O., Zou, X., Ressom, H., Chang, E., Srivastava, M., Clarke, R. & Kasid, U., Sep 2025, In: Oncology Letters. 30, 3, 409.Research output: Contribution to journal › Article › peer-review
Open Access -
iDDN: determining trans-omics network structure and rewiring with integrative differential dependency networks
Wang, Y., Fu, Y., Lu, Y., Zhang, Z., Clarke, R., Parker, S. J., Herrington, D. M., Yu, G. & Wang, Y., 2025, In: Bioinformatics Advances. 5, 1, vbaf086.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular mechanisms underlying TXNIP’s anti-tumor role in breast cancer, including interaction with a novel, pro-tumor partner: CAST
Singh, J., Sah, B., Deng, Y., Clarke, R. & Liu, L., Dec 2025, In: Cell Death and Disease. 16, 1, 236.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy
Mortazavi Farsani, S. S., Soni, J., Jin, L., Yadav, A. K., Bansal, S., Mi, T., Hilakivi-Clarke, L., Clarke, R., Youngblood, B., Cheema, A. & Verma, V., Jun 3 2025, In: Cell Metabolism. 37, 6, p. 1294-1310.e7Research output: Contribution to journal › Article › peer-review
11 Scopus citations
Datasets
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Data associated with the publication: Iron oxide nanoparticles inhibit tumor progression and suppress lung metastases in mouse models of breast cancer
Korangath, P., Jin, L., Yang, C.-T., Healy, S., Guo, X., Ke, S., Grüttner, C., Hu, C., Gabrielson, K., Foote, J., Clarke, R., Ivkov, R., Rivkov1@JhmiEdu, F. Q. A. T. D. C. R. I. V., Dataservices@JhuEdu, F. Q. A. A. T. T. D. C. J. H. U. D. S. V. & Ivkov, R., Johns Hopkins Research Data Repository, 2024
DOI: 10.7281/t1/ktog9w, https://archive.data.jhu.edu/citation?persistentId=doi:10.7281/T1/KTOG9W
Dataset
Press/Media
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Innovative tech used in research leads to breakthrough in understanding breast cancer
10/25/20
1 item of Media coverage
Press/Media: Research
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The Hormel Institute welcomes Dr. Robert Clarke
Clarke, R. R., Cramer, C. & Hilakivi-Clarke, L.
8/31/20
1 item of Media coverage
Press/Media: Expert Comment or Interview