1968 …2001

Research output per year

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Research Output

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Article
2001

L-Quisqualic acid transport into hippocampal neurons by a cystine-sensitive carrier is required for the induction of quisqualate sensitization

Chase, L. A., Roon, R. J., Wellman, L., Beitz, A. J. & Koerner, J. F., Sep 6 2001, In : Neuroscience. 106, 2, p. 287-301 15 p.

Research output: Contribution to journalArticle

22 Scopus citations
1999

Cyclobutane quisqualic acid analogues as selective mGluR5a metabotropic glutamic acid receptor ligands

Littman, L., Tokar, C., Venkatraman, S., Roon, R. J., Koerner, J. F., Robinson, M. B. & Johnson, R. L., May 6 1999, In : Journal of Medicinal Chemistry. 42, 9, p. 1639-1647 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
1996

Persistent depression of synaptic responses occurs in quisqualate sensitized hippocampal slices after exposure to L-aspartate-β-hydroxamate

Roon, R. J. & Koerner, J. F., Sep 23 1996, In : Brain Research. 734, 1-2, p. 223-228 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
1995

A 3-Amino-4-hydroxy-3-cyclobutene-1,2-dione-Containing Glutamate Analogue Exhibiting High Affinity to Excitatory Amino Acid Receptors

Chan, P. C. M., Roon, R. J., Koerner, J. F., Taylor, N. J. & Honek, J. F., Oct 1 1995, In : Journal of Medicinal Chemistry. 38, 22, p. 4433-4438 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
1994

Synthesis of Oxadiazolidinedione Derivatives as Quisqualic Acid Analogues and Their Evaluation at a Quisqualate-Sensitized Site in the Rat Hippocampus

Venkatraman, S., Roon, R. J., Schulte, M. K., Koerner, J. F. & Johnson, R. L., Nov 1 1994, In : Journal of medicinal chemistry. 37, 23, p. 3939-3946 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Utilization of the resolved l-isomer of 2-amino-6-phosphonohexanoic acid (l-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons

Schulte, M. K., Roon, R. J., Chalmers, D. J., Sunter, D. C. & Koerner, J. F., Jun 27 1994, In : Brain Research. 649, 1-2, p. 203-207 5 p.

Research output: Contribution to journalArticle

21 Scopus citations
1993

Quisqualic acid induced sensitization and the active uptake of l-quisqualic acid by hippocampal slices

Schulte, M. K., Roon, R. J. & Koerner, J. F., Mar 5 1993, In : Brain Research. 605, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
1992

Quisqualic Acid Analogues: Synthesis of β-Heterocyclic 2-Aminopropanoic Acid Derivatives and Their Activity at a Novel Quisqualate-Sensitized Site

Subasinghe, N., Schulte, M., Roon, R. J., Koerner, J. F. & Johnson, R. L., Nov 1 1992, In : Journal of medicinal chemistry. 35, 24, p. 4602-4607 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
1990

Synthesis of Acyclic and Dehydroaspartic Acid Analogues of Ac-Asp-Glu-OH and Their Inhibition of Rat Brain N-Acetylated α-Linked Acidic Dipeptidase (NAALA Dipeptidase)

Subasinghe, N., Schulte, M., Chan, M. Y. M., Roon, R. J., Koerner, J. F. & Johnson, R. L., Oct 1990, In : Journal of medicinal chemistry. 33, 10, p. 2734-2744 11 p.

Research output: Contribution to journalArticle

38 Scopus citations
1989

High-Affinity Transport of L-Glutamine by a Plasma Membrane Preparation from Rat Brain

Roon, R. J., Shofner, S. A. & Koerner, J. F., Jan 1 1989, In : Biochemistry. 28, 20, p. 8083-8087 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
1988

Asparaginase II of Saccharomyces cerevisiae. Characterization of the ASP3 gene

Kim, K. W., Kamerud, J. Q., Livingston, D. M. & Roon, R. J., Jan 1 1988, In : Journal of Biological Chemistry. 263, 24, p. 11948-11953 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
1986

Asparaginase II of Saccharomyces cerevisiae: Selection of four mutations that cause derepressed enzyme synthesis

Kamerud, J. Q. & Roon, R. J., Jan 1 1986, In : Journal of bacteriology. 165, 1, p. 293-296 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
1984

A laboratory course in clinical biochemistry for first year medical students

Van Pilsum, J. F. & Roon, R. J., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 1757

Research output: Contribution to journalArticle

Asparaginase II of Saccharomyces cerevisiae: Positive selection of two mutations that prevent enzyme synthesis

Kim, K. W. & Roon, R. J., Jan 1 1984, In : Journal of Bacteriology. 157, 3, p. 958-961 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Secretion of asparaginase II by yeast spheroplasts

Kyu Won Kim, W. K., Kamerud, J. & Roon, R. J., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 1611

Research output: Contribution to journalArticle

1983

Asparaginase II of Saccharomyces cerevisiae: Comparison of Enzyme Stability in Vivo and in Vitro

Kim, K. W. & Roon, R. J., Jan 1 1983, In : Biochemistry. 22, 11, p. 2704-2707 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

The experimental use of cooperative learning groups in a biochemistry laboratory course for first-year medical students

Roon, R. J., Van Pilsum, J. F., Harris, I., Rosenberg, P., Johnson, R., Liaw, C. & Rosenthal, L., Jan 1983, In : Biochemical Education. 11, 1, p. 12-15 4 p.

Research output: Contribution to journalArticle

1982

Derepression of asparaginase II during exponential growth of Saccharomyces cerevisiae on ammonium ion

Roon, R. J., Murdoch, M., Kunze, B. & Dunlop, P. C., Nov 1982, In : Archives of Biochemistry and Biophysics. 219, 1, p. 101-109 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nitrogen catabolite repression in a glutamate auxotroph of Saccharomyces cerevisiae

Kang, L., Keeler, M. L., Dunlop, P. C. & Roon, R. J., Jan 1 1982, In : Journal of Bacteriology. 151, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Transport and metabolic effect of α-aminoisobutyric acid in Saccharomyces cerevisiae

Kim, K. W. & Roon, R. J., Jan 1 1982, In : Federation Proceedings. 41, 4, p. No. 5239

Research output: Contribution to journalArticle

Transport and metabolic effects of α-aminoisobutyric acid in saccharomyces cerevisiae

Kim, K. W. & Roon, R. J., Nov 24 1982, In : BBA - General Subjects. 719, 2, p. 356-362 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
1981

Temperature-sensitive glucosamine auxotroph of Saccharomyces cerevisiae

Ballou, L., Grove, J. R., Roon, R. J., Wiggs, J. & Ballou, C. E., Jan 1 1981, In : Unknown Journal. 1, 1, p. 9-12 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
1980

Nitrogen catabolite repression of asparaginase II in Saccharomyces cerevisiae

Dunlop, P. C., Meyer, G. M. & Roon, R. J., Jan 1 1980, In : Journal of bacteriology. 143, 1, p. 422-426 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Reactions of asparaginase II of Saccharomyces cerevisiae. A mechanistic analysis of hydrolysis and hydroxylaminolysis

Dunlop, P. C., Meyer, G. M. & Roon, R. J., Jan 1 1980, In : Journal of Biological Chemistry. 255, 4, p. 1542-1546 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Transport and metabolism of N-δ-chloroacetyl-l-ornithine by Saccharomyces cerevisiae

Larimore, F. S., Kuisk, I., Korkowski, P. M. & Roon, R. J., Jan 1 1980, In : Archives of Biochemistry and Biophysics. 204, 1, p. 234-240 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
1979

Transport and metabolism of N-δ-chloroacetyl-L-ornithine by Saccharomyces cerevisiae

Larimore, F. S. & Roon, R. J., Jan 1 1979, In : Federation Proceedings. 38, 3 I, p. No.86

Research output: Contribution to journalArticle

1978

Characterization of a Dio-9-resistant strain of Saccharomyces cerevisiae

Roon, R. J., Larimore, F. S., Meyer, G. M. & Kreisle, R. A., Jan 15 1978, In : Archives of Biochemistry and Biophysics. 185, 1, p. 142-150 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Characterization of two forms of asparaginase in Saccharomyces cerevisiae

Dunlop, P. C., Meyer, G. M., Ban, D. & Roon, R. J., Jan 1 1978, In : Journal of Biological Chemistry. 253, 4, p. 1297-1304 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Possible Site-Specific Reagent for the General Amino Acid Transport System of Saccharomyces cerevisiae

Larimore, F. S. & Roon, R. J., Jan 1 1978, In : Biochemistry. 17, 3, p. 431-436 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
1977

Evidence for a common component in kinetically distinct transport systems of Saccharomyces cerevisiae

Roon, R. J., Meyer, G. M. & Larimore, F. S., Jan 1 1977, In : MGG Molecular & General Genetics. 158, 2, p. 185-191 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Negative interactions between amino acid and methylamine/ammonia transport systems of Saccharomyces cerevisiae

Roon, R. J., Levy, J. S. & Larimore, F., Dec 1 1977, In : Journal of Biological Chemistry. 252, 11, p. 3599-3604 6 p.

Research output: Contribution to journalArticle

41 Scopus citations
1976

Utilization of D asparagine by Saccharomyces cerevisiae

Dunlop, P. C., Roon, R. J. & Even, H. L., Dec 1 1976, In : Journal of Bacteriology. 125, 3, p. 999-1004 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
1975

Inhibition of amino acid transport by ammonium ion in Saccharomyces cerevisiae

Roon, R. J., Larimore, F. & Levy, J. S., Dec 1 1975, In : Journal of bacteriology. 124, 1, p. 325-331 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

L Asparaginase of Saccharomyces cerevisiae: an extracellular enzyme

Dunlop, P. C. & Roon, R. J., Dec 1 1975, In : Journal of bacteriology. 122, 3, p. 1017-1024 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Methylamine and ammonia transport in Saccharomyces cerevisiae

Roon, R. J., Even, H. L., Dunlop, P. & Larimore, F. L., Dec 1 1975, In : Journal of bacteriology. 122, 2, p. 502-503 2 p.

Research output: Contribution to journalArticle

80 Scopus citations
1974

Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide dependent enzyme from Saccharomyces cerevisiae

Roon, R. J., Even, H. L. & Larimore, F., Dec 1 1974, In : Journal of bacteriology. 118, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
1972

Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase.

Roon, R. J. & Barker, H. A., Jan 1 1972, In : Journal of bacteriology. 109, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Urea amidolyase. I. Properties of the enzyme from Candida utilis.

Roon, R. J. & Levenberg, B., Jul 10 1972, In : Journal of Biological Chemistry. 247, 13, p. 4107-4113 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Urea amidolyase. The involvement of biotin in urea cleavage.

Roon, R. J., Hampshire, J. & Levenberg, B., Dec 10 1972, In : Journal of Biological Chemistry. 247, 23, p. 7539-7545 7 p.

Research output: Contribution to journalArticle

29 Scopus citations
1970

ATP: Urea Amidolyase (ADP) (Candida utilis)

Roon, R. J. & Levenberg, B., Jan 1 1970, In : Methods in enzymology. 17, p. 317-324 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

CO2 fixation and the involvement of allophanate in the biotin-enzyme-catalyzed cleavage of urea.

Roon, R. J. & Levenberg, B., Sep 10 1970, In : Journal of Biological Chemistry. 245, 17, p. 4593-4595 3 p.

Research output: Contribution to journalArticle

26 Scopus citations
1969

Separation and differential sensitivity toward avidin of carbamyl phosphate synthetase and urea amidolyase

Rognes, S. E., Roon, R. J. & Levenberg, B., Jun 1969, In : FEBS Letters. 3, 4, p. 233-236 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
1968

An adenosine triphosphate-dependent, avidin-sensitive enzymatic cleavage of urea in yeast and green algae.

Roon, R. J. & Levenberg, B., Oct 10 1968, In : Journal of Biological Chemistry. 243, 19, p. 5213-5215 3 p.

Research output: Contribution to journalArticle

48 Scopus citations