Projects per year
Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
- 10 Similar Profiles
Human Herpesvirus 1
Medicine & Life Sciences
Glycoproteins
Medicine & Life Sciences
Cell Fusion
Medicine & Life Sciences
Virus Internalization
Medicine & Life Sciences
Endonucleases
Medicine & Life Sciences
Hepacivirus
Medicine & Life Sciences
Cytomegalovirus
Medicine & Life Sciences
Viruses
Chemical Compounds
Network
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Projects 2009 2023
Discovery and development of novel anti-HCMV agents targeting the UL89 terminase protein
Geraghty, R. J., Aihara, H., Wang, Z. & Xie, J.
NIH Nat'l Inst of Allergy & Infect Dis
1/25/19 → 12/31/23
Project: Research project
Proteins
terminase
Receptor recognition mechanisms of coronaviruses
NIH Nat'l Inst of Allergy & Infect Dis
5/15/10 → 4/30/15
Project: Research project
Coronavirus
Membrane fusion during HSV-1 entry
NIH Nat'l Inst of Allergy & Infect Dis
5/15/09 → 4/30/12
Project: Research project
Membrane Fusion
Human Herpesvirus 1
Research Output 1993 2019
- 33 Article
FRET-based assay using a three-way junction DNA substrate to identify inhibitors of human cytomegalovirus pUL89 endonuclease activity
Wang, Y. & Geraghty, R. J., Jan 15 2019, In : European Journal of Pharmaceutical Sciences. 127, p. 29-37 9 p.Research output: Contribution to journal › Article
Endonucleases
Cytomegalovirus
Viral Genome
DNA
Viral DNA
2
Citations
(Scopus)
Hydroxypyridonecarboxylic Acids as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease
Kankanala, J., Wang, Y., Geraghty, R. J. & Wang, Z., Aug 20 2018, In : ChemMedChem. 13, 16, p. 1658-1663 6 p.Research output: Contribution to journal › Article
Endonucleases
Cytomegalovirus
Acids
Molecular modeling
Viral DNA
5
Citations
(Scopus)
Metal-chelating 3-hydroxypyrimidine-2,4-diones inhibit human cytomegalovirus pUL89 endonuclease activity and virus replication
Wang, Y., Tang, J., Wang, Z. & Geraghty, R. J., Apr 1 2018, In : Antiviral Research. 152, p. 10-17 8 p.Research output: Contribution to journal › Article
Endonucleases
Virus Replication
Cytomegalovirus
Metals
Enzyme-Linked Immunosorbent Assay
3
Citations
(Scopus)
Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis
Qiu, L., Patterson, S. E., Bonnac, L. F. & Geraghty, R. J., Apr 19 2018, In : PLoS Neglected Tropical Diseases. 12, 4, e0006421.Research output: Contribution to journal › Article
Dengue Virus
Nucleosides
Mutagenesis
Antiviral Agents
Dengue
5
Citations
(Scopus)
A fluorescence-based high-throughput assay to identify inhibitors of tyrosylprotein sulfotransferase activity
Zhou, W., Wang, Y., Xie, J. & Geraghty, R. J., Jan 22 2017, In : Biochemical and Biophysical Research Communications. 482, 4, p. 1207-1212 6 p.Research output: Contribution to journal › Article
Assays
Fluorescence
Throughput
Libraries
Sulfotransferases