1987 …2024

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Article
2020

Repression of oncogenic cap-mediated translation by 4Ei-10 diminishes proliferation, enhances chemosensitivity and alters expression of malignancy-related proteins in mesothelioma

Ahmad, Z., Jacobson, B. A., McDonald, M. W., Vattendahl Vidal, N., Vattendahl Vidal, G., Chen, S., Dillenburg, M., Okon, A. M., Patel, M. R., Wagner, C. R. & Kratzke, R. A., Feb 1 2020, In : Cancer chemotherapy and pharmacology. 85, 2, p. 425-432 8 p.

Research output: Contribution to journalArticle

2019

Gemcitabine and metabolite pharmacokinetics in advanced NSCLC patients after bronchial artery infusion and intravenous infusion

Alharbi, A. F., Kratzke, R. A., D’Cunha, J., Maddaus, M. A., Sanghavi, K. & Kirstein, M. N., Feb 5 2019, In : Cancer chemotherapy and pharmacology. 83, 2, p. 387-391 5 p.

Research output: Contribution to journalArticle

Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer

De, A., Jacobson, B. A., Peterson, M. S., Stelzner, M. E., Jay-Dixon, J., Kratzke, M. G., Patel, M. R., Bitterman, P. B. & Kratzke, R. A., May 1 2019, In : Cancer gene therapy. 26, 5-6, p. 157-165 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

JAK/STAT inhibition with ruxolitinib enhances oncolytic virotherapy in non-small cell lung cancer models

Patel, M. R., Dash, A., Jacobson, B. A., Ji, Y., Baumann, D., Ismail, K. & Kratzke, R. A., Nov 1 2019, In : Cancer gene therapy. 26, 11-12, p. 411-418 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

LACE-Bio: Validation of Predictive and/or Prognostic Immunohistochemistry/Histochemistry-based Biomarkers in Resected Non–small-cell Lung Cancer

LACE-Bio Steering Committee, Mar 2019, In : Clinical Lung Cancer. 20, 2, p. 66-73.e6

Research output: Contribution to journalArticle

6 Scopus citations
2018

4EGI-1 represses cap-dependent translation and regulates genome-wide translation in malignant pleural mesothelioma

De, A., Jacobson, B. A., Peterson, M. S., Jay-Dixon, J., Kratzke, M. G., Sadiq, A. A., Patel, M. R. & Kratzke, R. A., Apr 1 2018, In : Investigational New Drugs. 36, 2, p. 217-229 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Asbestos-Related Disease

Kratzke, P. & Kratzke, R. A., Jan 1 2018, (Accepted/In press) In : Journal of Radiology Nursing.

Research output: Contribution to journalArticle

2 Scopus citations

Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancer

on behalf of the LACE-Bio Consortium, Jun 1 2018, In : Translational Lung Cancer Research. 7, 3, p. 416-427 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Smoking, sex, and non–Small cell lung cancer: Steroid hormone receptors in tumor tissue (S0424)

Cheng, T. Y. D., Darke, A. K., Redman, M. W., Zirpoli, G. R., Davis, W., Ondracek, R. P., Bshara, W., Omilian, A. R., Kratzke, R. A., Reid, M. E., Molina, J. R., Kolesar, J. M., Chen, Y., MacRae, R. M., Moon, J., Mack, P., Gandara, D. R., Kelly, K., Santella, R. M., Albain, K. S. & 1 others, Ambrosone, C. B., Jan 1 2018, In : Journal of the National Cancer Institute. 110, 7, p. 734-742 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Tumor mutation burden as a biomarker in resected non-small-cell lung cancer

Devarakonda, S., Rotolo, F., Tsao, M. S., Lanc, I., Brambilla, E., Masood, A., Olaussen, K. A., Fulton, R., Sakashita, S., McLeer-Florin, A., Ding, K., Le Teuff, G., Shepherd, F. A., Pignon, J. P., Graziano, S. L., Kratzke, R., Soria, J. C., Seymour, L., Govindan, R. & Michiels, S., Oct 20 2018, In : Journal of Clinical Oncology. 36, 30, p. 2995-3006 12 p.

Research output: Contribution to journalArticle

34 Scopus citations
2017

Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma

Jacobson, B. A., Sadiq, A. A., Tang, S., Jay-Dixon, J., Patel, M. R., Drees, J., Sorenson, B. S., Russell, S. J. & Kratzke, R. A., Jan 1 2017, In : Oncotarget. 8, 38, p. 63096-63109 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Oncolytic viral therapy for mesothelioma

Pease, D. F. & Kratzke, R. A., Aug 24 2017, In : Frontiers in Oncology. 7, AUG, 179.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Pooled analysis of the prognostic and predictive effects of TP53 comutation status combined with KRAS or EGFR mutation in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy

Shepherd, F. A., Lacas, B., Le Teuff, G., Hainaut, P., Jänne, P. A., Pignon, J. P., Le Chevalier, T., Seymour, L., Douillard, J. Y., Graziano, S., Brambilla, E., Pirker, R., Filipits, M., Kratzke, R., Soria, J. C. & Tsao, M. S., Jun 20 2017, In : Journal of Clinical Oncology. 35, 18, p. 2018-2027 10 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Validation of progression-free survival as a surrogate endpoint for overall survival inmalignant mesothelioma: Analysis of cancer and leukemia group B and north central cancer treatment group (Alliance) trials

Wang, X., Wang, X., Hodgson, L., George, S. L., Sargent, D. J., Foster, N. R., Ganti, A. K., Stinchcombe, T. E., Crawford, J., Kratzke, R., Adjei, A. A., Kindler, H. L., Vokes, E. E. & Pang, H., Feb 10 2017, In : Oncologist. 22, 2, p. 189-198 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2016

A 10-Gene Yin Yang Expression Ratio Signature for Stage IA and IB Non-Small Cell Lung Cancer

Xu, W., Jia, G., Davie, J. R., Murphy, L., Kratzke, R. & Banerji, S., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 12, p. 2150-2160 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Detection of occult micrometastases in patients with clinical stage i non-small-cell lung cancer: A prospective analysis of mature results of CALGB 9761 (Alliance)

Martin, L. W., D'Cunha, J., Wang, X., Herzan, D., Gu, L., Abraham, N., Demmy, T. L., Detterbeck, F. C., Groth, S. S., Harpole, D. H., Krasna, M. J., Kernstine, K., Kohman, L. J., Patterson, G. A., Sugarbaker, D. J., Vollmer, R. T., Maddaus, M. A. & Kratzke, R. A., May 1 2016, In : Journal of Clinical Oncology. 34, 13, p. 1484-1491 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Prognostic effect of tumor lymphocytic infiltration in resectable non-small-cell lung cancer

Brambilla, E., Le Teuff, G., Marguet, S., Lantuejoul, S., Dunant, A., Graziano, S., Pirker, R., Douillard, J. Y., Le Chevalier, T., Filipits, M., Rosell, R., Kratzke, R., Popper, H., Soria, J. C., Shepherd, F. A., Seymour, L. & Tsao, M. S., Apr 10 2016, In : Journal of Clinical Oncology. 34, 11, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

100 Scopus citations
2015

Antisense oligonucleotide targeting eukaryotic translation initiation factor 4E reduces growth and enhances chemosensitivity of non-small-cell lung cancer cells

Thumma, S. C., Jacobson, B. A., Patel, M. R., Konicek, B. W., Franklin, M. J., Jay-Dixon, J., Sadiq, A., De, A., Graff, J. R. & Kratzke, R. A., Aug 18 2015, In : Cancer gene therapy. 22, 8, p. 396-401 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Subtype classification of lung adenocarcinoma predicts benefit from adjuvant chemotherapy in patients undergoing complete resection

Tsao, M. S., Marguet, S., Le Teuff, G., Lantuejoul, S., Shepherd, F. A., Seymour, L., Kratzke, R., Graziano, S. L., Popper, H. H., Rosell, R., Douillard, J. Y., Le-Chevalier, T., Pignon, J. P., Soria, J. C. & Brambilla, E. M., Oct 20 2015, In : Journal of Clinical Oncology. 33, 30, p. 3439-3446 8 p.

Research output: Contribution to journalArticle

117 Scopus citations

Targeting topoisomerase II activity in NSCLC with 9-aminoacridine derivatives

Ferguson, D. M., Jacobson, B. A., Jay-Dixon, J., Patel, M. R., Kratzke, R. A. & Raza, A., Jan 1 2015, In : Anticancer Research. 35, 10, p. 5211-5218 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma

Jacobson, B. A., Chen, E. Z., Tang, S., Belgum, H. S., McCauley, J. A., Evenson, K. A., Etchison, R. G., Jay-Dixon, J., Patel, M. R., Raza, A., Saluja, A. K., D’Cunha, J. & Kratzke, R. A., Jan 1 2015, In : Genes and Cancer. 6, 3-4, p. 144-152 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

Patel, M. R., Jacobson, B. A., Ji, Y., Drees, J., Tang, S., Xiong, K., Wang, H., Prigge, J. E., Dash, A. S., Kratzke, A. K., Mesev, E., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Jan 1 2015, In : Oncotarget. 6, 32, p. 33165-33177 13 p.

Research output: Contribution to journalArticle

38 Scopus citations
2014

Measles vaccine strains for virotherapy of non-small-cell lung carcinoma

Patel, M. R., Jacobson, B. A., Belgum, H., Raza, A., Sadiq, A., Drees, J., Wang, H., Jay-Dixon, J., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Aug 2014, In : Journal of Thoracic Oncology. 9, 8, p. 1101-1110 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

SLC28A3 genotype and gemcitabine rate of infusion affect dFdCTP metabolite disposition in patients with solid tumours

Khatri, A., Williams, B. W., Fisher, J., Brundage, R. C., Gurvich, V. J., Lis, L. G., Skubitz, K. M., Dudek, A. Z., Greeno, E. W., Kratzke, R. A., Lamba, J. K. & Kirstein, M. N., Jan 21 2014, In : British Journal of Cancer. 110, 2, p. 304-312 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells

Chen, E. Z., Jacobson, B. A., Patel, M. R., Okon, A. M., Li, S., Xiong, K., Vaidya, A. J., Bitterman, P. B., Wagner, C. R. & Kratzke, R. A., Aug 2014, In : Investigational New Drugs. 32, 4, p. 598-603 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Cross-validation analysis of the prognostic significance of mucin expression in patients with resected non-small cell lung cancer treated with adjuvant chemotherapy: Results from IALT, JBR.10 and ANITA

Graziano, S. L., Lacas, B., Vollmer, R., Kratzke, R., Popper, H., Filipits, M., Seymour, L., Shepherd, F. A., Rosell, R., Veillard, A. S., Taron, M. & Pignon, J. P., Oct 1 2013, In : Lung Cancer. 82, 1, p. 149-155 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations

ERCC1 isoform expression and DNA repair in non-small-cell lung cancer

Friboulet, L., Olaussen, K. A., Pignon, J. P., Shepherd, F. A., Tsao, M. S., Graziano, S., Kratzke, R., Douillard, J. Y., Seymour, L., Pirker, R., Filipits, M., André, F., Solary, E., Ponsonnailles, F., Robin, A., Stoclin, A., Dorvault, N., Commo, F., Adam, J., Vanhecke, E. & 8 others, Saulnier, P., Thomale, J., Le Chevalier, T., Dunant, A., Rousseau, V., Le Teuff, G., Brambilla, E. & Soria, J. C., Mar 21 2013, In : New England Journal of Medicine. 368, 12, p. 1101-1110 10 p.

Research output: Contribution to journalArticle

271 Scopus citations

Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In Vivo

Rousalova, I., Banerjee, S., Sangwan, V., Evenson, K., McCauley, J. A., Kratzke, R., Vickers, S. M., Saluja, A. & D'Cunha, J., Oct 15 2013, In : PloS one. 8, 10, e77411.

Research output: Contribution to journalArticle

33 Scopus citations

MiR-1 induces growth arrest and apoptosis in malignant mesothelioma

Xu, Y., Zheng, M., Merritt, R. E., Shrager, J. B., Wakelee, H. A., Kratzke, R. A. & Hoang, C. D., Nov 2013, In : Chest. 144, 5, p. 1632-1643 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Phase II study of topotecan and bevacizumab in advanced, refractory non-small-cell lung cancer

Powell, S. F., Beitinjaneh, A., Tessema, M., Bliss, R. L., Kratzke, R. A., Leach, J. & Dudek, A. Z., Sep 1 2013, In : Clinical Lung Cancer. 14, 5, p. 495-501 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non–small-cell lung cancer in four trials of adjuvant chemotherapy

Shepherd, F. A., Domerg, C., Hainaut, P., Jänne, P. A., Pignon, J. P., Graziano, S., Douillard, J. Y., Brambilla, E., Le Chevalier, T., Seymour, L., Bourredjem, A., Le Teuff, G., Pirker, R., Filipits, M., Rosell, R., Kratzke, R., Bandarchi, B., Ma, X., Capelletti, M., Soria, J. C. & 1 others, Tsao, M. S., Jun 10 2013, In : Journal of Clinical Oncology. 31, 17, p. 2173-2181 9 p.

Research output: Contribution to journalArticle

156 Scopus citations
11 Scopus citations

Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide

Jacobson, B. A., Thumma, S. C., Jay-Dixon, J., Patel, M. R., Dubear Kroening, K., Kratzke, M. G., Etchison, R. G., Konicek, B. W., Graff, J. R. & Kratzke, R. A., Nov 18 2013, In : PloS one. 8, 11, e81669.

Research output: Contribution to journalArticle

22 Scopus citations
42 Scopus citations

Yin Yang Gene Expression Ratio Signature for Lung Cancer Prognosis

Xu, W., Banerji, S., Davie, J. R., Kassie, F., Yee, D. & Kratzke, R., Jul 17 2013, In : PloS one. 8, 7, e68742.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: Analysis of four randomized trials

Reiman, T., Lai, R., Veillard, A. S., Paris, E., Soria, J. C., Rosell, R., Taron, M., Graziano, S., Kratzke, R., Seymour, L., Shepherd, F. A., Pignon, J. P. & Sève, P., Jan 1 2012, In : Annals of Oncology. 23, 1, p. 86-93 8 p., mdr033.

Research output: Contribution to journalArticle

59 Scopus citations

CYFRA 21-1 as a prognostic and predictive marker in advanced non-small-cell lung cancer in a prospective trial: CALGB 150304

Edelman, M. J., Hodgson, L., Rosenblatt, P. Y., Christenson, R. H., Vokes, E. E., Wang, X. & Kratzke, R., Apr 1 2012, In : Journal of Thoracic Oncology. 7, 4, p. 649-654 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
11 Scopus citations

Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation

Patel, M. R., Sadiq, A. A., Jay-Dixon, J., Jirakulaporn, T., Jacobson, B. A., Farassati, F., Bitterman, P. B. & Kratzke, R. A., Feb 1 2012, In : International Journal of Oncology. 40, 2, p. 577-582 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors

Mitra, A. K., Kirstein, M. N., Khatri, A., Skubitz, K. M., Dudek, A. Z., Greeno, E. W., Kratzke, R. A. & Lamba, J. K., Jul 1 2012, In : Pharmacogenomics. 13, 9, p. 1009-1021 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Phase II study of dasatinib in patients with previously treated malignant mesothelioma (Cancer and leukemia group B 30601): A brief report

Dudek, A. Z., Pang, H., Kratzke, R. A., Otterson, G. A., Hodgson, L., Vokes, E. E. & Kindler, H. L., Apr 1 2012, In : Journal of Thoracic Oncology. 7, 4, p. 755-759 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 trial

Jänne, P. A., Wang, X., Socinski, M. A., Crawford, J., Stinchcombe, T. E., Gu, L., Capelletti, M., Edelman, M. J., Villalona-Calero, M. A., Kratzke, R., Vokes, E. E. & Miller, V. A., Jun 10 2012, In : Journal of Clinical Oncology. 30, 17, p. 2063-2069 7 p.

Research output: Contribution to journalArticle

163 Scopus citations

Vatalanib in malignant mesothelioma: A phase II trial by the Cancer and Leukemia Group B (CALGB 30107)

Jahan, T., Gu, L., Kratzke, R., Dudek, A., Otterson, G. A., Wang, X., Green, M., Vokes, E. E. & Kindler, H. L., Jun 1 2012, In : Lung Cancer. 76, 3, p. 393-396 4 p.

Research output: Contribution to journalArticle

47 Scopus citations
2011

Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues

Kodali, D., Rawal, A., Ninan, M. J., Patel, M. R., Mesa, H., Knapp, D., Schnitzer, B., Kratzke, R. A. & Gupta, P., Mar 1 2011, In : Archives of Pathology and Laboratory Medicine. 135, 3, p. 365-371 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Morphine-induced epidermal growth factor pathway activation in non-small cell lung cancer

Fujioka, N., Nguyen, J., Chen, C., Li, Y., Pasrija, T., Niehans, G., Johnson, K. N., Gupta, V., Kratzke, R. A. & Gupta, K., Dec 1 2011, In : Anesthesia and analgesia. 113, 6, p. 1353-1364 12 p.

Research output: Contribution to journalArticle

61 Scopus citations

Prediction of postoperative recurrence-free survival in non-small cell lung cancer by using an internationally validated gene expression model

Mitra, R., Lee, J., Jo, J., Milani, M., McClintick, J. N., Edenberg, H. J., Kesler, K. A., Rieger, K. M., Badve, S., Cummings, O. W., Mohiuddin, A., Thomas, D. G., Luo, X., Juliar, B. E., Li, L., Mesaros, C., Blair, I. A., Srirangam, A., Kratzke, R. A., McDonald, C. J. & 2 others, Kim, J. & Potter, D. A., May 1 2011, In : Clinical Cancer Research. 17, 9, p. 2934-2946 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Randomized phase II study of pemetrexed, carboplatin, and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small-cell lung cancer: Cancer and leukemia group B trial 30407

Govindan, R., Bogart, J., Stinchcombe, T., Wang, X., Hodgson, L., Kratzke, R. A., Garst, J., Brotherton, T. & Vokes, E. E., Aug 10 2011, In : Journal of Clinical Oncology. 29, 23, p. 3120-3125 6 p.

Research output: Contribution to journalArticle

137 Scopus citations

Serum vascular endothelial growth factor and COX-2/5-LOX inhibition in advanced non-small cell lung cancer: Cancer and leukemia group B 150304

Edelman, M. J., Hodgson, L., Wang, X., Christenson, R., Jewell, S., Vokes, E. & Kratzke, R., Nov 2011, In : Journal of Thoracic Oncology. 6, 11, p. 1902-1906 5 p.

Research output: Contribution to journalArticle

9 Scopus citations