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Research Output 1987 2019

2019

Gemcitabine and metabolite pharmacokinetics in advanced NSCLC patients after bronchial artery infusion and intravenous infusion

Alharbi, A. F., Kratzke, R. A., D’Cunha, J., Maddaus, M. A., Sanghavi, K. J. & Kirstein, M. N., Feb 5 2019, In : Cancer chemotherapy and pharmacology. 83, 2, p. 387-391 5 p.

Research output: Contribution to journalArticle

gemcitabine
Bronchial Arteries
Pharmacokinetics
Metabolites
Intravenous Infusions

Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer

De, A., Jacobson, B. A., Peterson, M. S., Stelzner, M. E., Jay-Dixon, J., Kratzke, M. G., Patel, M. R., Bitterman, P. B. & Kratzke, R. A., May 1 2019, In : Cancer gene therapy. 26, 5-6, p. 157-165 9 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4F
Non-Small Cell Lung Carcinoma
Genome
Growth
gemcitabine
1 Citation (Scopus)

JAK/STAT inhibition with ruxolitinib enhances oncolytic virotherapy in non-small cell lung cancer models

Patel, M. R., Dash, A., Jacobson, B. A., Ji, Y., Baumann, D., Ismail, K. & Kratzke, R. A., Jan 1 2019, (Accepted/In press) In : Cancer gene therapy.

Research output: Contribution to journalArticle

Oncolytic Virotherapy
Vesicular Stomatitis
Non-Small Cell Lung Carcinoma
Interferons
Viruses
3 Citations (Scopus)

LACE-Bio: Validation of Predictive and/or Prognostic Immunohistochemistry/Histochemistry-based Biomarkers in Resected Non–small-cell Lung Cancer

LACE-Bio Steering Committee, Mar 1 2019, In : Clinical Lung Cancer. 20, 2, p. 66-73.e6

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Biomarkers
Immunohistochemistry
Patient Selection
Adjuvant Chemotherapy
2018
2 Citations (Scopus)

4EGI-1 represses cap-dependent translation and regulates genome-wide translation in malignant pleural mesothelioma

De, A., Jacobson, B. A., Peterson, M. S., Jay-Dixon, J., Kratzke, M. G., Sadiq, A. A., Patel, M. R. & Kratzke, R. A., Apr 1 2018, In : Investigational New Drugs. 36, 2, p. 217-229 13 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4F
Genome
gemcitabine
Pemetrexed
Osteopontin
1 Citation (Scopus)

Asbestos-Related Disease

Kratzke, P. & Kratzke, R. A., Jan 1 2018, (Accepted/In press) In : Journal of Radiology Nursing.

Research output: Contribution to journalArticle

Asbestos
Asbestosis
Mesothelioma
Minerals
Lung Neoplasms
3 Citations (Scopus)

Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancer

on behalf of the LACE-Bio Consortium, Jun 1 2018, In : Translational Lung Cancer Research. 7, 3, p. 416-427 12 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Disease-Free Survival
Gene Dosage
Genome
Adjuvant Chemotherapy
1 Citation (Scopus)

Meet the new boss: Lung cancer staging

Begnaud, A. & Kratzke, R. A., Mar 1 2018, In : Journal of Thoracic Disease. 10, 3, p. 1329-1331 3 p.

Research output: Contribution to journalEditorial

Open Access
Neoplasm Staging
Lung Neoplasms
2 Citations (Scopus)

Smoking, sex, and non–Small cell lung cancer: Steroid hormone receptors in tumor tissue (S0424)

Cheng, T. Y. D., Darke, A. K., Redman, M. W., Zirpoli, G. R., Davis, W., Ondracek, R. P., Bshara, W., Omilian, A. R., Kratzke, R. A., Reid, M. E., Molina, J. R., Kolesar, J. M., Chen, Y., MacRae, R. M., Moon, J., Mack, P., Gandara, D. R., Kelly, K., Santella, R. M., Albain, K. S. & 1 others, Ambrosone, C. B., Jan 1 2018, In : Journal of the National Cancer Institute. 110, 7, p. 734-742 9 p.

Research output: Contribution to journalArticle

Steroid Receptors
Non-Small Cell Lung Carcinoma
Estrogen Receptors
Smoking
Hormones
18 Citations (Scopus)

Tumor mutation burden as a biomarker in resected non-small-cell lung cancer

Devarakonda, S., Rotolo, F., Tsao, M. S., Lanc, I., Brambilla, E., Masood, A., Olaussen, K. A., Fulton, R., Sakashita, S., McLeer-Florin, A., Ding, K., Le Teuff, G., Shepherd, F. A., Pignon, J. P., Graziano, S. L., Kratzke, R. A., Soria, J. C., Seymour, L., Govindan, R. & Michiels, S., Oct 20 2018, In : Journal of Clinical Oncology. 36, 30, p. 2995-3006 12 p.

Research output: Contribution to journalArticle

Tumor Burden
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Biomarkers
Mutation
2017
4 Citations (Scopus)

Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma

Jacobson, B. A., Sadiq, A. A., Tang, S., Jay-Dixon, J., Patel, M. R., Drees, J., Sorenson, B. S., Russell, S. J. & Kratzke, R. A., Jan 1 2017, In : Oncotarget. 8, 38, p. 63096-63109 14 p.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
Measles virus
Virus Diseases
Mesothelioma
Repressor Proteins
7 Citations (Scopus)

Oncolytic viral therapy for mesothelioma

Pease, D. F. & Kratzke, R. A., Aug 24 2017, In : Frontiers in Oncology. 7, AUG, 179.

Research output: Contribution to journalArticle

Mesothelioma
Oncolytic Virotherapy
Therapeutics
Neoplasms
Virus Diseases
24 Citations (Scopus)

Pooled analysis of the prognostic and predictive effects of TP53 comutation status combined with KRAS or EGFR mutation in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy

Shepherd, F. A., Lacas, B., Le Teuff, G., Hainaut, P., Jänne, P. A., Pignon, J. P., Le Chevalier, T., Seymour, L., Douillard, J. Y., Graziano, S., Brambilla, E., Pirker, R., Filipits, M., Kratzke, R., Soria, J. C. & Tsao, M. S., Jun 20 2017, In : Journal of Clinical Oncology. 35, 18, p. 2018-2027 10 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Non-Small Cell Lung Carcinoma
Mutation
Disease-Free Survival
Adenocarcinoma

Targeting eukaryotic protein translation in mesothelioma

Kratzke, R. A., Jun 1 2017, In : Translational Lung Cancer Research. 6, 3, p. 343-349 7 p.

Research output: Contribution to journalReview article

Open Access
Mesothelioma
Protein Biosynthesis
Oncolytic Virotherapy
RNA Cap-Binding Proteins
Translational Medical Research
2 Citations (Scopus)

Validation of progression-free survival as a surrogate endpoint for overall survival inmalignant mesothelioma: Analysis of cancer and leukemia group B and north central cancer treatment group (Alliance) trials

Wang, X., Wang, X., Hodgson, L., George, S. L., Sargent, D. J., Foster, N. R., Ganti, A. K., Stinchcombe, T. E., Crawford, J., Kratzke, R., Adjei, A. A., Kindler, H. L., Vokes, E. E. & Pang, H., Feb 10 2017, In : Oncologist. 22, 2, p. 189-198 10 p.

Research output: Contribution to journalArticle

Open Access
Mesothelioma
Disease-Free Survival
Leukemia
Biomarkers
Survival
2016
6 Citations (Scopus)

A 10-Gene Yin Yang Expression Ratio Signature for Stage IA and IB Non-Small Cell Lung Cancer

Xu, W., Jia, G., Davie, J. R., Murphy, L., Kratzke, R. & Banerji, S., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 12, p. 2150-2160 11 p.

Research output: Contribution to journalArticle

Yin-Yang
Non-Small Cell Lung Carcinoma
Genes
Lung Neoplasms
Survival
21 Citations (Scopus)

Detection of occult micrometastases in patients with clinical stage i non-small-cell lung cancer: A prospective analysis of mature results of CALGB 9761 (Alliance)

Martin, L. W., D'Cunha, J., Wang, X., Herzan, D., Gu, L., Abraham, N., Demmy, T. L., Detterbeck, F. C., Groth, S. S., Harpole, D. H., Krasna, M. J., Kernstine, K., Kohman, L. J., Patterson, G. A., Sugarbaker, D. J., Vollmer, R. T., Maddaus, M. A. & Kratzke, R. A., May 1 2016, In : Journal of Clinical Oncology. 34, 13, p. 1484-1491 8 p.

Research output: Contribution to journalArticle

Neoplasm Micrometastasis
Non-Small Cell Lung Carcinoma
Immunohistochemistry
Lymph Nodes
Reverse Transcriptase Polymerase Chain Reaction

MicroRNA as Biomarkers of Malignant Mesothelioma

Hoang, C. D. & Kratzke, R. A., Sep 29 2016, Translating MicroRNAs to the Clinic. Elsevier Inc., p. 203-221 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biomarkers
MicroRNAs
Gene expression
Tumors
Neoplasms
81 Citations (Scopus)

Prognostic effect of tumor lymphocytic infiltration in resectable non-small-cell lung cancer

Brambilla, E., Le Teuff, G., Marguet, S., Lantuejoul, S., Dunant, A., Graziano, S., Pirker, R., Douillard, J. Y., Le Chevalier, T., Filipits, M., Rosell, R., Kratzke, R. A., Popper, H., Soria, J. C., Shepherd, F. A., Seymour, L. & Tsao, M. S., Apr 10 2016, In : Journal of Clinical Oncology. 34, 11, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Neoplasms
Disease-Free Survival
Survival
Adjuvant Chemotherapy
2015
14 Citations (Scopus)

Antisense oligonucleotide targeting eukaryotic translation initiation factor 4E reduces growth and enhances chemosensitivity of non-small-cell lung cancer cells

Thumma, S. C., Jacobson, B. A., Patel, M. R., Konicek, B. W., Franklin, M. J., Jay-Dixon, J., Sadiq, A., De, A., Graff, J. R. & Kratzke, R. A., Aug 18 2015, In : Cancer gene therapy. 22, 8, p. 396-401 6 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4E
Eukaryotic Initiation Factors
Antisense Oligonucleotides
Non-Small Cell Lung Carcinoma
Growth
64 Citations (Scopus)

Epigenetics of lung cancer

Langevin, S. M., Kratzke, R. A. & Kelsey, K. T., Jan 1 2015, In : Translational Research. 165, 1, p. 74-90 17 p.

Research output: Contribution to journalReview article

Epigenomics
Lung Neoplasms
Untranslated RNA
Histone Code
Histones
104 Citations (Scopus)

Subtype classification of lung adenocarcinoma predicts benefit from adjuvant chemotherapy in patients undergoing complete resection

Tsao, M. S., Marguet, S., Le Teuff, G., Lantuejoul, S., Shepherd, F. A., Seymour, L., Kratzke, R. A., Graziano, S. L., Popper, H. H., Rosell, R., Douillard, J. Y., Le-Chevalier, T., Pignon, J. P., Soria, J. C. & Brambilla, E. M., Oct 20 2015, In : Journal of Clinical Oncology. 33, 30, p. 3439-3446 8 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Disease-Free Survival
Survival
Proportional Hazards Models
Adenocarcinoma of lung
1 Citation (Scopus)

Targeting topoisomerase II activity in NSCLC with 9-aminoacridine derivatives

Ferguson, D. M., Jacobson, B. A., Jay-Dixon, J., Patel, M. R., Kratzke, R. A. & Raza, A., Jan 1 2015, In : Anticancer Research. 35, 10, p. 5211-5218 8 p.

Research output: Contribution to journalArticle

Aminacrine
Acridines
Type II DNA Topoisomerase
Non-Small Cell Lung Carcinoma
Poisons
12 Citations (Scopus)

Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma

Jacobson, B. A., Chen, E. Z., Tang, S., Belgum, H. S., McCauley, J. A., Evenson, K. A., Etchison, R. G., Jay-Dixon, J., Patel, M. R., Raza, A., Saluja, A. K., D’Cunha, J. & Kratzke, R. A., Jan 1 2015, In : Genes and Cancer. 6, 3-4, p. 144-152 9 p.

Research output: Contribution to journalArticle

Mesothelioma
Prodrugs
Heterografts
Growth
Cell Survival
31 Citations (Scopus)

Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

Patel, M. R., Jacobson, B. A., Ji, Y., Drees, J., Tang, S., Xiong, K., Wang, H., Prigge, J. E., Dash, A. S., Kratzke, A. K., Mesev, E., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Jan 1 2015, In : Oncotarget. 6, 32, p. 33165-33177 13 p.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Non-Small Cell Lung Carcinoma
Interferons
Viruses
Neoplasms
2014
1 Citation (Scopus)

Genetic Engineering of Oncolytic Viruses for Cancer Therapy

Patel, M. R. & Kratzke, R. A., Nov 17 2014, Translating Gene Therapy to the Clinic: Techniques and Approaches. Elsevier Inc., p. 261-279 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Oncolytic Virotherapy
Genetic engineering
Genetic Engineering
Viruses
Oncolytic Viruses
10 Citations (Scopus)

Measles vaccine strains for virotherapy of non-small-cell lung carcinoma

Patel, M. R., Jacobson, B. A., Belgum, H., Raza, A., Sadiq, A., Drees, J., Wang, H., Jay-Dixon, J., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Jan 1 2014, In : Journal of Thoracic Oncology. 9, 8, p. 1101-1110 10 p.

Research output: Contribution to journalArticle

Measles Vaccine
Measles virus
Non-Small Cell Lung Carcinoma
Carcinoembryonic Antigen
Virus Diseases
12 Citations (Scopus)

SLC28A3 genotype and gemcitabine rate of infusion affect dFdCTP metabolite disposition in patients with solid tumours

Khatri, A., Williams, B. W., Fisher, J., Brundage, R., Gurvich, V. J., Lis, L. G., Skubitz, K. M., Dudek, A. Z., Greeno, E. W., Kratzke, R. A., Lamba, J. K. & Kirstein, M. N., Jan 21 2014, In : British Journal of Cancer. 110, 2, p. 304-312 9 p.

Research output: Contribution to journalArticle

gemcitabine
Pharmacokinetics
Genotype
Neoplasms
Cytidine Deaminase
10 Citations (Scopus)

Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells

Chen, E. Z., Jacobson, B. A., Patel, M. R., Okon, A. M., Li, S., Xiong, K., Vaidya, A. J., Bitterman, P. B., Wagner, C. R. & Kratzke, R. A., Jan 1 2014, In : Investigational New Drugs. 32, 4, p. 598-603 6 p.

Research output: Contribution to journalArticle

Mesothelioma
Protein Biosynthesis
Pemetrexed
Prodrugs
Messenger RNA
2013
4 Citations (Scopus)

Cross-validation analysis of the prognostic significance of mucin expression in patients with resected non-small cell lung cancer treated with adjuvant chemotherapy: Results from IALT, JBR.10 and ANITA

Graziano, S. L., Lacas, B., Vollmer, R., Kratzke, R. A., Popper, H., Filipits, M., Seymour, L., Shepherd, F. A., Rosell, R., Veillard, A. S., Taron, M. & Pignon, J. P., Oct 1 2013, In : Lung Cancer. 82, 1, p. 149-155 7 p.

Research output: Contribution to journalArticle

Mucins
Adjuvant Chemotherapy
Non-Small Cell Lung Carcinoma
Histology
Adenocarcinoma
1 Citation (Scopus)
Pleura
Therapeutic Irrigation
Non-Small Cell Lung Carcinoma
Leukemia
Messenger RNA
2 Citations (Scopus)

Detection of mesothioloma remains a conundrum

Kratzke, R. A., Feb 20 2013, In : Journal of the National Cancer Institute. 105, 4, p. 254-255 2 p.

Research output: Contribution to journalEditorial

Pleural Neoplasms
Pleura
Asbestos
Mesothelioma
Occupational Exposure
259 Citations (Scopus)

ERCC1 isoform expression and DNA repair in non-small-cell lung cancer

Friboulet, L., Olaussen, K. A., Pignon, J. P., Shepherd, F. A., Tsao, M. S., Graziano, S., Kratzke, R., Douillard, J. Y., Seymour, L., Pirker, R., Filipits, M., André, F., Solary, E., Ponsonnailles, F., Robin, A., Stoclin, A., Dorvault, N., Commo, F., Adam, J., Vanhecke, E. & 8 others, Saulnier, P., Thomale, J., Le Chevalier, T., Dunant, A., Rousseau, V., Le Teuff, G., Brambilla, E. & Soria, J. C., Mar 21 2013, In : New England Journal of Medicine. 368, 12, p. 1101-1110 10 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
DNA Repair
Protein Isoforms
Antibodies
Cisplatin

Lung cancer

Kirstein, M. N., Kratzke, R. A. & Dudek, A. Z., Jul 8 2013, Koda-Kimble and Young's Applied Therapeutics: The Clinical Use of Drugs. Wolters Kluwer Health Adis (ESP), p. 2210-2222 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lung Neoplasms
32 Citations (Scopus)

Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In Vivo

Rousalova, I., Banerjee, S., Sangwan, V., Evenson, K., McCauley, J. A., Kratzke, R. A., Vickers, S. M., Saluja, A. K. & D'Cunha, J., Oct 15 2013, In : PLoS One. 8, 10, e77411.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
carcinoma
apoptosis
lungs
Cells
28 Citations (Scopus)

MiR-1 induces growth arrest and apoptosis in malignant mesothelioma

Xu, Y., Zheng, M., Merritt, R. E., Shrager, J. B., Wakelee, H. A., Kratzke, R. A. & Hoang, C. D., Jan 1 2013, In : Chest. 144, 5, p. 1632-1643 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Apoptosis
Growth
Cell Line
Neoplasms
60 Citations (Scopus)

Oncolytic virus therapy for cancer: The first wave of translational clinical trials

Patel, M. R. & Kratzke, R. A., Jan 1 2013, In : Translational Research. 161, 4, p. 355-364 10 p.

Research output: Contribution to journalReview article

Oncolytic Virotherapy
Viruses
Clinical Trials
Oncolytic Viruses
Neoplasms
10 Citations (Scopus)

Phase II study of topotecan and bevacizumab in advanced, refractory non-small-cell lung cancer

Powell, S. F., Beitinjaneh, A., Tessema, M., Bliss, R. L., Kratzke, R. A., Leach, J. & Dudek, A. Z., Sep 1 2013, In : Clinical Lung Cancer. 14, 5, p. 495-501 7 p.

Research output: Contribution to journalArticle

Topotecan
Non-Small Cell Lung Carcinoma
Disease-Free Survival
Salvage Therapy
Poisons
144 Citations (Scopus)

Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non–small-cell lung cancer in four trials of adjuvant chemotherapy

Shepherd, F. A., Domerg, C., Hainaut, P., Jänne, P. A., Pignon, J. P., Graziano, S., Douillard, J. Y., Brambilla, E., Le Chevalier, T., Seymour, L., Bourredjem, A., Le Teuff, G., Pirker, R., Filipits, M., Rosell, R., Kratzke, R., Bandarchi, B., Ma, X., Capelletti, M., Soria, J. C. & 1 others, Tsao, M. S., Jun 10 2013, In : Journal of Clinical Oncology. 31, 17, p. 2173-2181 9 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Non-Small Cell Lung Carcinoma
Codon
Mutation
Observation
9 Citations (Scopus)
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Eukaryotic Initiation Factor-4F
Phosphorylation

Response

Xu, Y., Zheng, M., Khuong, A., Merritt, R. E., Shrager, J. B., Wakelee, H. A., Kratzke, R. A. & Hoang, C. D., Jan 1 2013, In : Chest. 144, 6, p. 1971-1972 2 p.

Research output: Contribution to journalLetter

Neoplasm RNA
Neoplastic Gene Expression Regulation
Mesothelioma
MicroRNAs
Lung Neoplasms
20 Citations (Scopus)

Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide

Jacobson, B. A., Thumma, S. C., Jay-Dixon, J., Patel, M. R., Dubear Kroening, K., Kratzke, M. G., Etchison, R. G., Konicek, B. W., Graff, J. R. & Kratzke, R. A., Nov 18 2013, In : PloS one. 8, 11, e81669.

Research output: Contribution to journalArticle

gemcitabine
Pemetrexed
mesothelioma
Antisense Oligonucleotides
Mesothelioma
38 Citations (Scopus)
gemcitabine
Guanosine Monophosphate
Lung Neoplasms
Breast Neoplasms
Prodrugs
13 Citations (Scopus)

Yin Yang Gene Expression Ratio Signature for Lung Cancer Prognosis

Xu, W., Banerji, S., Davie, J. R., Kassie, F., Yee, D. & Kratzke, R. A., Jul 17 2013, In : PloS one. 8, 7, e68742.

Research output: Contribution to journalArticle

Yin-Yang
lung neoplasms
Transcriptome
Gene expression
prognosis
2012
57 Citations (Scopus)

Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: Analysis of four randomized trials

Reiman, T., Lai, R., Veillard, A. S., Paris, E., Soria, J. C., Rosell, R., Taron, M., Graziano, S., Kratzke, R. A., Seymour, L., Shepherd, F. A., Pignon, J. P. & Sève, P., Jan 1 2012, In : Annals of Oncology. 23, 1, p. 86-93 8 p., mdr033.

Research output: Contribution to journalArticle

Validation Studies
Tubulin
Adjuvant Chemotherapy
Non-Small Cell Lung Carcinoma
Disease-Free Survival
13 Citations (Scopus)

Cyclooxygenase-2 (COX-2) as a predictive marker for the use of COX-2 inhibitors in advanced non-small-cell lung cancer

Edelman, M. J., Hodgson, L., Wang, X., Kratzke, R. A. & Vokes, E. E., Jun 1 2012, In : Journal of Clinical Oncology. 30, 16, p. 2019-2020 2 p.

Research output: Contribution to journalLetter

Antineoplastic Combined Chemotherapy Protocols
Cyclooxygenase 2 Inhibitors
Cyclooxygenase 2
Tumor Biomarkers
Non-Small Cell Lung Carcinoma
33 Citations (Scopus)

CYFRA 21-1 as a prognostic and predictive marker in advanced non-small-cell lung cancer in a prospective trial: CALGB 150304

Edelman, M. J., Hodgson, L., Rosenblatt, P. Y., Christenson, R. H., Vokes, E. E., Wang, X. & Kratzke, R. A., Apr 1 2012, In : Journal of Thoracic Oncology. 7, 4, p. 649-654 6 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Survival
Celecoxib
gemcitabine
zileuton
11 Citations (Scopus)
Topoisomerase II Inhibitors
Acridines
Mesothelioma
Cell Proliferation
Apoptosis
11 Citations (Scopus)

Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation

Patel, M. R., Sadiq, A. A., Jay-Dixon, J., Jirakulaporn, T., Jacobson, B. A., Farassati, F., Bitterman, P. B. & Kratzke, R. A., Feb 1 2012, In : International Journal of Oncology. 40, 2, p. 577-582 6 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Non-Small Cell Lung Carcinoma
Translational Peptide Chain Initiation
Mesothelioma
Intercellular Signaling Peptides and Proteins
20 Citations (Scopus)

Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors

Mitra, A. K., Kirstein, M. N., Khatri, A., Skubitz, K. M., Dudek, A. Z., Greeno, E. W., Kratzke, R. A. & Lamba, J. K., Jul 1 2012, In : Pharmacogenomics. 13, 9, p. 1009-1021 13 p.

Research output: Contribution to journalArticle

gemcitabine
Pharmacogenetics
Pharmacokinetics
Single Nucleotide Polymorphism
Neoplasms