Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
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Bespoke Micellar Nanoparticles (MNPs) for In Vivo Delivery of Digital Base Editor Treatments for Primary Immunodeficiency Disease
McIvor, R. S. (PI), Moriarity, B. S. (PI), Reineke, T. M. (PI), Sarupria, S. (PI), Chang, J. W. (Other Role), Diers, M. D. (Other Role) & Stelljes, E. (Other Role)
NIH NATIONAL INST OF ALLERGY & INFECT DI
9/11/25 → 8/31/26
Project: Research project
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In vivo and ex vivo gene editing for Artemis-deficient SCID
McIvor, R. S. (PI), Moriarity, B. S. (Co-Principal Investigator) & Webber, B. R. (Co-Principal Investigator)
NIH NATIONAL INST OF ALLERGY & INFECT DI
7/7/25 → 6/30/27
Project: Research project
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Viral vector technology for cell type specific gene delivery
Aslanidi, G. (PI), Schmidt, D. (PI), Gordon, W. R. (CoI), LeBeau, A. (CoI) & McIvor, R. S. (Other Role)
NIH NIGMS NATL INST OF GENERAL
3/1/22 → 2/28/27
Project: Research project
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Gene Therapy for MPS IV A in a Novel Porcine Model of the Disease
McIvor, R. S. (PI)
RECOMBINETICS, INC., NIH NIAMS NATIONALL INSTITUTE OF ARTHRIT
9/18/24 → 7/3/25
Project: Research project
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Lentiviral Gene Therapy in a Novel Porcine Model of Mucopolysaccharidosis IV A
McIvor, R. S. (PI)
8/1/22 → 7/31/24
Project: Research project
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Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial
Lou, E., Choudhry, M. S., Starr, T. K., Folsom, T. D., Bell, J., Rathmann, B., DeFeo, A. P., Kim, J., Slipek, N., Jin, Z., Sumstad, D., Klebanoff, C. A., Ladner, K., Sarkari, A., McIvor, R. S., Murray, T. A., Miller, J. S., Rao, M., Jensen, E. & Ankeny, J. & 13 others, , May 2025, In: The Lancet Oncology. 26, 5, p. 559-570 12 p.Research output: Contribution to journal › Article › peer-review
38 Link opens in a new tab Scopus citations -
Advancing gene targeting for primary immune deficiencies: Adenine base editing of the human IL2RG locus for correction of SCID-X1
McIvor, R. S., Eaton, E. J., Webber, B. R. & Moriarity, B. S., Jun 5 2024, In: Molecular Therapy. 32, 6, p. 1606-1608 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
Webber, B. R., Johnson, M. J., Skeate, J. G., Slipek, N. J., Lahr, W. S., DeFeo, A. P., Mills, L. J., Qiu, X., Rathmann, B., Diers, M. D., Wick, B., Henley, T., Choudhry, M., Starr, T. K., McIvor, R. S. & Moriarity, B. S., Dec 2024, In: Nature Biomedical Engineering. 8, 12, p. 1553-1570 18 p., 5222.Research output: Contribution to journal › Article › peer-review
Open Access18 Link opens in a new tab Scopus citations -
Comparative dose effectiveness of intravenous and intrathecal AAV9.CB7.hIDS, RGX-121, in mucopolysaccharidosis type II mice
Smith, M. C., Belur, L. R., Karlen, A. D., Erlanson, O., Furcich, J., Lund, T. C., Seelig, D., Kitto, K. F., Fairbanks, C. A., Kim, K. H., Buss, N. & McIvor, R. S., Mar 14 2024, In: Molecular Therapy Methods and Clinical Development. 32, 1, 101201.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations -
Intrathecal or intravenous AAV9-IDUA/RGX-111 at minimal effective dose prevents cardiac, skeletal and neurologic manifestations of murine MPS I
Belur, L. R., Huber, A. K., Mantone, H., Robertson, M., Smith, M. C., Karlen, A. D., Kitto, K. F., Ou, L., Whitley, C. B., Braunlin, E., Furcich, J., Lund, T. C., Seelig, D., Fairbanks, C. A., Buss, N., Kim, K. H. & McIvor, R. S., Dec 12 2024, In: Molecular Therapy Methods and Clinical Development. 32, 4, 101369.Research output: Contribution to journal › Article › peer-review
Open Access