1982 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article

Acyl chain-length asymmetry alters the interfacial elastic interactions of phosphatidylcholines

Ali, S., Smaby, J. M., Momsen, M. M., Brockman, H. L. & Brown, R. E., Jan 1998, In : Biophysical journal. 74, 1, p. 338-348 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Acyl Structure Regulates Galactosylceramide's Interfacial Interactions

Ali, S., Smaby, J. M. & Brown, R. E., Jan 1 1993, In : Biochemistry. 32, 43, p. 11696-11703 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

A fluorescence resonance energy transfer approach for monitoring protein-mediated glycolipid transfer between vesicle membranes

Mattjus, P., Molotkovsky, J. G., Smaby, J. M. & Brown, R. E., Mar 15 1999, In : Analytical Biochemistry. 268, 2, p. 297-304 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

An expedient synthesis of fluorescent labeled ceramide-1-phosphate analogues

Boldyrev, I. A., Brown, R. E. & Molotkovsky, J. G., Sep 1 2013, In : Russian Journal of Bioorganic Chemistry. 39, 5, p. 539-542 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Arabidopsis accelerated cell death 11, ACD11, Is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels

Simanshu, D. K., Zhai, X., Munch, D., Hofius, D., Markham, J. E., Bielawski, J., Bielawska, A., Malinina, L., Molotkovsky, J. G., Mundy, J. W., Patel, D. J. & Brown, R. E., Jan 10 2014, In : Cell reports. 6, 2, p. 388-399 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Bilayer nanotubes and helical ribbons formed by hydrated galactosylceramides: acyl chain and headgroup effects

Kulkarni, V. S., Anderson, W. H. & Brown, R. E., Jan 1 1995, In : Biophysical journal. 69, 5, p. 1976-1986 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by αB-crystallin through inhibition of RAS activation

Li, D. W. C., Liu, J. P., Mao, Y. W., Xiang, H., Wang, J., Ma, W-Y., Dong, Z., Pike, H. M., Brown, R. E. & Reed, J. C., Sep 1 2005, In : Molecular biology of the cell. 16, 9, p. 4437-4453 17 p.

Research output: Contribution to journalArticle

142 Scopus citations

Characterization of the lateral distribution of fluorescent lipid in binary-constituent lipid monolayers by principal component analysis

Brown, R. E., Sugár, I. P., Zhai, X., Boldyrev, I. A., Molotkovsky, J. G. & Brockman, H. L., May 26 2010, In : International Journal of Biomedical Imaging. 2010, 125850.

Research output: Contribution to journalArticle

2 Scopus citations

Charged membrane surfaces impede the protein-mediated transfer of glycosphingolipids between phospholipid bilayers

Mattjus, P., Pike, H. M., Molotkovsky, J. G. & Brown, R. E., Feb 8 2000, In : Biochemistry. 39, 5, p. 1067-1075 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cholesterol decreases the interfacial elasticity and detergent solubility of sphingomyelins

Li, X. M., Momsen, M. M., Smaby, J. M., Brockman, H. L. & Brown, R. E., May 22 2001, In : Biochemistry. 40, 20, p. 5954-5963 10 p.

Research output: Contribution to journalArticle

125 Scopus citations

Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects: Studies with cholesterol enantiomers

Westover, E. J., Covey, D. F., Brockman, H. L., Brown, R. E. & Pike, L. J., Dec 19 2003, In : Journal of Biological Chemistry. 278, 51, p. 51125-51133 9 p.

Research output: Contribution to journalArticle

112 Scopus citations

Cholesterol-induced interfacial area condensations of galactosylceramides and sphingomyelins with identical acyl chains

Smaby, J. M., Momsen, M., Kulkarni, V. S. & Brown, R. E., May 7 1996, In : Biochemistry. 35, 18, p. 5696-5704 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Cholesterol's Interfacial Interactions with Galactosylceramides

Ali, S., Smaby, J. M., Brockman, H. L. & Brown, R. E., Mar 1 1994, In : Biochemistry. 33, 10, p. 2900-2906 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Cholesterol's Interfacial Interactions with Sphingomyelins and Phosphatidylcholines: Hydrocarbon Chain Structure Determines the Magnitude of Condensation

Smaby, J. M., Brockman, H. L. & Brown, R. E., Aug 1 1994, In : Biochemistry. 33, 31, p. 9135-9142 8 p.

Research output: Contribution to journalArticle

161 Scopus citations

Cloning and expression of glycolipid transfer protein from bovine and porcine brain

Lin, X., Mattjus, P., Pike, H. M., Windebank, A. J. & Brown, R. E., Feb 18 2000, In : Journal of Biological Chemistry. 275, 7, p. 5104-5110 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Conformational folding and stability of the HET-C2 glycolipid transfer protein fold: Does a molten globule-like state regulate activity?

Kenoth, R., Kamlekar, R. K., Simanshu, D. K., Gao, Y-G., Malinina, L., Prendergast, F. G., Molotkovsky, J. G., Patel, D. J., Venyaminov, S. Y. & Brown, R. E., Jun 14 2011, In : Biochemistry. 50, 23, p. 5163-5171 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation

Mishra, S. K., Gao, Y-G., Deng, Y., Chalfant, C. E., Hinchcliffe, E. H. & Brown, R. E., May 4 2018, In : Autophagy. 14, 5

Research output: Contribution to journalArticle

9 Scopus citations

Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein

Samygina, V. R., Popov, A. N., Cabo-Bilbao, A., Ochoa-Lizarralde, B., Goni-De-Cerio, F., Zhai, X., Molotkovsky, J. G., Patel, D. J., Brown, R. E. & Malinina, L., Nov 9 2011, In : Structure. 19, 11, p. 1644-1654 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Fluorescence evidence for cholesterol regular distribution in phosphatidylcholine and in sphingomyelin lipid bilayers

Chong, P. L. G., Liu, F., Wang, M. M., Truong, K., Sugar, I. P. & Brown, R. E., Jan 1 1996, In : Journal of Fluorescence. 6, 4, p. 221-230 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Functional evaluation of tryptophans in glycolipid binding and membrane interaction by HET-C2, a fungal glycolipid transfer protein

Kenoth, R., Zou, X., Simanshu, D. K., Pike, H. M., Malinina, L., Patel, D. J., Brown, R. E. & Kamlekar, R. K., May 2018, In : Biochimica et Biophysica Acta - Biomembranes. 1860, 5, p. 1069-1076 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
6 Scopus citations

GLTP-fold interaction with planar phosphatidylcholine surfaces is synergistically stimulated by phosphatidic acid and phosphatidylethanolamine

Zhai, X., Momsen, W. E., Malakhov, D. A., Boldyrev, I. A., Momsen, M. M., Molotkovsky, J. G., Brockman, H. L. & Brown, R. E., Apr 1 2013, In : Journal of Lipid Research. 54, 4, p. 1103-1113 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: Insights into glycolipid binding affinity

Zhai, X., Malakhova, M. L., Pike, H. M., Benson, L. M., Bergen, H. R., Sugár, I. P., Malinina, L., Patel, D. J. & Brown, R. E., May 15 2009, In : Journal of Biological Chemistry. 284, 20, p. 13620-13628 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Glycolipid intermembrane transfer is accelerated by HET-C2, a filamentous fungus gene product involved in the cell-cell incompatibility response

Mattjus, P., Turcq, B., Pike, H. M., Molotkovsky, J. G. & Brown, R. E., Jan 21 2003, In : Biochemistry. 42, 2, p. 535-542 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Glycolipids are not extracted from phospholipid bilayers by binding to ferritin-lectin conjugates

Brown, R. E., Allietta, M., Tillack, T. W. & Thompson, T. E., Jun 23 1983, In : BBA - Biomembranes. 731, 3, p. 495-499 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Glycolipid transfer protein from bovine brain

Wong, M., Brown, R. E., Barenholz, Y. & Thompson, T. E., 1984, In : Biochemistry. 23, 26, p. 6498-6505 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Glycolipid transfer protein interaction with bilayer vesicles: Modulation by changing lipid composition

Rao, C. S., Chung, T., Pike, H. M. & Brown, R. E., Dec 2005, In : Biophysical journal. 89, 6, p. 4017-4028 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Glycolipid transfer protein mediated transfer of glycosphingolipids between membranes: A model for action based on kinetic and thermodynamic analyses

Rao, C. S., Lin, X., Pike, H. M., Molotkovsky, J. G. & Brown, R. E., Nov 2 2004, In : Biochemistry. 43, 43, p. 13805-13815 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

How α-helical motifs form functionally diverse lipid-binding compartments

Malinina, L., Patel, D. J. & Brown, R. E., Jun 20 2017, In : Annual Review of Biochemistry. 86, p. 609-636 28 p.

Research output: Contribution to journalArticle

8 Scopus citations

Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold

Kamlekar, R. K., Gao, Y-G., Kenoth, R., Molotkovsky, J. G., Prendergast, F. G., Malinina, L., Patel, D. J., Wessels, W. S., Venyaminov, S. Y. & Brown, R. E., Oct 20 2010, In : Biophysical journal. 99, 8, p. 2626-2635 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Human GLTP and mutant forms of ACD11 suppress cell death in the Arabidopsis acd11 mutant

Petersen, N. H. T., McKinney, L. V., Pike, H., Hofius, D., Zakaria, A., Brodersen, P., Petersen, M., Brown, R. E. & Mundy, J., Sep 1 2008, In : FEBS Journal. 275, 17, p. 4378-4388 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Human glycolipid transfer protein: Probing conformation using fluorescence spectroscopy

Li, X. M., Malakhova, M. L., Lin, X., Pike, H. M., Chung, T., Molotkovsky, J. G. & Brown, R. E., Aug 10 2004, In : Biochemistry. 43, 31, p. 10285-10294 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Human glycolipid transfer protein (GLTP) expression modulates cell shape

Gao, Y., Chung, T., Zou, X., Pike, H. M. & Brown, R. E., May 24 2011, In : PloS one. 6, 5, e19990.

Research output: Contribution to journalArticle

9 Scopus citations

Human glycolipid transfer protein (GLTP) genes: Organization, transcriptional status and evolution

Zou, X., Chung, T., Lin, X., Malakhova, M. L., Pike, H. M. & Brown, R. E., Feb 8 2008, In : BMC Genomics. 9, 72.

Research output: Contribution to journalArticle

16 Scopus citations

Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: Involvement of the bioactive sphingolipid ceramide

Zou, X., Gao, Y-G., Ruvolo, V. R., Gardner, T. L., Ruvolo, P. P. & Brown, R. E., Jan 14 2011, In : Journal of Biological Chemistry. 286, 2, p. 1301-1311 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Inhibition of activator protein 1 activity and neoplastic transformation by aspirin

Dong, Z., Huang, C., Brown, R. E. & Ma, W-Y., Apr 11 1997, In : Journal of Biological Chemistry. 272, 15, p. 9962-9970 9 p.

Research output: Contribution to journalArticle

163 Scopus citations

Inhibition of tumor growth by a newly-identified activator for epidermal fatty acid binding protein

Rao, E., Singh, P., Zhai, X., Li, Y., Zhu, G., Zhang, Y., Hao, J., Chi, Y-I., Brown, R. E., Cleary, M. P. & Li, B., Jan 1 2015, In : Oncotarget. 6, 10, p. 7815-7827 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Interactions of phospholipid bilayer vesicles with monomolecular films at the air-water interface

Kulkarni, V. S. & Brown, R. E., May 15 1994, In : Thin Solid Films. 244, 1-2, p. 869-873 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Interfacial interactions of ceramide with dimyristoylphosphatidylcholine: Impact of the N-acyl chain

Holopainen, J. M., Brockman, H. L., Brown, R. E. & Kinnunen, P. K. J., Jan 1 2001, In : Biophysical journal. 80, 2, p. 765-775 11 p.

Research output: Contribution to journalArticle

91 Scopus citations

In Vitro Measurement of Sphingolipid Intermembrane Transport Illustrated by GLTP Superfamily Members

Kenoth, R., Brown, R. E. & Kamlekar, R. K., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1949, p. 237-256 20 p.

Research output: Contribution to journalArticle

Involvement of nuclear factor of activated T cells activation in UV response. Evidence from cell culture and transgenic mice

Huang, C., Mattjus, P., Ma, W-Y., Rincon, M., Chen, N. Y., Brown, R. E. & Dong, Z., Mar 31 2000, In : Journal of Biological Chemistry. 275, 13, p. 9143-9149 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Involvement of the Acid Sphingomyelinase Pathway in UVA-induced Apoptosis

Zhang, Y., Mattjus, P., Schmidt, P. C., Dong, Z., Zhong, S., Ma, W-Y., Brown, R. E., Bode, A. M., Schmidt, H. H. O. & Dong, Z., Apr 13 2001, In : Journal of Biological Chemistry. 276, 15, p. 11775-11782 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense

Brodersen, P., Petersen, M., Pike, H. M., Olszak, B., Skov, S., Ødum, N., Jørgensen, L. B., Brown, R. E. & Mundy, J., Feb 15 2002, In : Genes and Development. 16, 4, p. 490-502 13 p.

Research output: Contribution to journalArticle

290 Scopus citations

Lactosylceramide: Lateral Interactions with cholesterol

Zhai, X., Li, X. M., Momsen, M. M., Brockman, H. L. & Brown, R. E., Oct 2006, In : Biophysical journal. 91, 7, p. 2490-2500 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Lactosylceramide: Effect of acyl chain structure on phase behavior and molecular packing

Li, X. M., Momsen, M. M., Brockman, H. L. & Brown, R. E., Sep 2002, In : Biophysical journal. 83, 3, p. 1535-1546 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Lipid nanotubes as substrates for helical crystallization of macromolecules

Wilson-Kubalek, E. M., Brown, R. E., Celia, H. & Milligan, R. A., Jul 7 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 14, p. 8040-8045 6 p.

Research output: Contribution to journalArticle

133 Scopus citations

Macro-ripple phase formation in bilayers composed of galactosylceramide and phosphatidylcholine

Brown, R. E., Anderson, W. H. & Kulkarni, V. S., Jan 1 1995, In : Biophysical journal. 68, 4, p. 1396-1405 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Measuring Lipid Transfer Protein Activity Using Bicelle-Dilution Model Membranes

Gao, Y-G., Le, T. M. L., Zhai, X., Boldyrev, I. A., Mishra, S. K., Tischer, A., Murayama, T., Nishida, A., Molotkovsky, J. G., Alam, A. & Brown, R. E., Jan 23 2020, In : Analytical Chemistry.

Research output: Contribution to journalArticle

Measuring Lipid Transfer Protein Activity Using Bicelle-Dilution Model Membranes

Gao, Y. G., My Le, L. T., Zhai, X., Boldyrev, I. A., Mishra, S. K., Tischer, A., Murayama, T., Nishida, A., Molotkovsky, J. G., Alam, A. & Brown, R. E., Feb 18 2020, In : Analytical chemistry. 92, 4, p. 3417-3425 9 p.

Research output: Contribution to journalArticle