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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Targeting N-Myc with Selective Aurora Kinase A Degraders for Neuroblastoma Therapy
Harki, D. A., Harris, R. & Levinson, N. M.
7/15/21 → 7/14/24
Project: Research project
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APOBEC3B and DNA Repair as Synthetic Lethal Combinations in CCOC
THE OVARIAN CANCER RESEARCH FUND INC
3/1/21 → 2/28/23
Project: Research project
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Implications and Vulnerabilities of APOBEC Mutagenesis in Breast Cancer
Memorial Sloan-Kettering Cancer Center
8/13/20 → 7/31/25
Project: Research project
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APOBEC3 Proteins in HIV Restriction
NIH Nat'l Inst of Allergy & Infect Dis
1/1/20 → 12/31/24
Project: Research project
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APOBEC MUTAGENESIS IN BREAST CANCER
Harris, R., Aihara, H., Harki, D. A., Largaespada, D. A. & Yee, D.
NIH NATIONAL CANCER INSTITUTE (NCI)
8/9/19 → 7/31/24
Project: Research project
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Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer
Baker, S. C., Mason, A. S., Slip, R. G., Skinner, K. T., Macdonald, A., Masood, O., Harris, R. S., Fenton, T. R., Periyasamy, M., Ali, S. & Southgate, J., Apr 8 2022, In: Oncogene. 41, 15, p. 2139-2151 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
Bergstrom, E. N., Luebeck, J., Petljak, M., Khandekar, A., Barnes, M., Zhang, T., Steele, C. D., Pillay, N., Landi, M. T., Bafna, V., Mischel, P. S., Harris, R. S. & Alexandrov, L. B., Feb 17 2022, In: Nature. 602, 7897, p. 510-517 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The current toolbox for APOBEC drug discovery
Grillo, M. J., Jones, K. F., Carpenter, M. A., Harris, R. & Harki, D. A., May 2022, In: Trends in Pharmacological Sciences. 43, 5, p. 362-377 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis
Wörmann, S. M., Zhang, A., Thege, F. I., Cowan, R. W., Rupani, D. N., Wang, R., Manning, S. L., Gates, C., Wu, W., Levin-Klein, R., Rajapakshe, K. I., Yu, M., Multani, A. S., Kang, Y., Taniguchi, C. M., Schlacher, K., Bellin, M. D., Katz, M. H. G., Kim, M. P., Fleming, J. B. & 7 others, , Dec 2021, In: Nature Cancer. 2, 12, p. 1338-1356 19 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
APOBECs and herpesviruses
Cheng, A. Z., Moraes, S. N., Shaban, N. M., Fanunza, E., Bierle, C. J., Southern, P. J., Bresnahan, W. A., Rice, S. A. & Harris, R. S., Feb 28 2021, In: Viruses. 13, 3, 390.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations