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  • 11 Similar Profiles
HIV-1 Medicine & Life Sciences
Cytosine Deaminase Medicine & Life Sciences
DNA Medicine & Life Sciences
Deamination Medicine & Life Sciences
Mutation Medicine & Life Sciences
Cytosine Medicine & Life Sciences
Mutagenesis Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 2005 2021

Breast Neoplasms
Therapeutics

APOBEC3 STRUCTURAL STUDIES

Harris, R., Aihara, H., Harki, D. A., Nazarian, S. & Shi, K.

NIH NIGMS NATL INST OF GENERAL

4/15/162/29/20

Project: Research project

Human Immunodeficiency Virus Proteins
Ovarian Neoplasms
Enzymes

Research Output 1994 2018

APOBEC3B Nuclear Localization Requires Two Distinct N-Terminal Domain Surfaces

Salamango, D. J., McCann, J. L., Demir, Ö., Brown, W. L., Amaro, R. E. & Harris, R., Aug 17 2018, In : Journal of Molecular Biology. 430, 17, p. 2695-2708 14 p.

Research output: Contribution to journalArticle

Cytosine Deaminase
Neoplasms
Uracil
Single-Stranded DNA
Cytosine

Apobec3H subcellular localization determinants define zipcode for targeting HIV-1 for restriction

Salamango, D. J., Becker, J. T., McCann, J. L., Cheng, A. Z., Demir, Ö., Amaro, R. E., Brown, W. L., Shaban, N. M. & Harris, R., Dec 1 2018, In : Molecular and cellular biology. 38, 23, e00356.

Research output: Contribution to journalArticle

HIV-1
Cell Nucleus Active Transport
Cytosine Deaminase
DNA
Mutagenesis

APOBEC3 Mediates Resistance to Oncolytic Viral Therapy

Huff, A. L., Wongthida, P., Kottke, T., Thompson, J. M., Driscoll, C. B., Schuelke, M., Shim, K. G., Harris, R., Molan, A. M., Pulido, J. S., Selby, P. J., Harrington, K. J., Melcher, A., Evgin, L. & Vile, R. G., Dec 21 2018, In : Molecular Therapy - Oncolytics. 11, p. 1-13 13 p.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Viruses
Virus Diseases
Oncolytic Virotherapy
Therapeutics
6 Citations

APOBEC Enzymes as Targets for Virus and Cancer Therapy

Olson, M. E., Harris, R. & Harki, D. A., Jan 18 2018, In : Cell Chemical Biology. 25, 1, p. 36-49 14 p.

Research output: Contribution to journalReview article

Viruses
Mutagenesis
Uracil
Genes
Cytosine
2 Citations

Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution

Peretti, A., Geoghegan, E. M., Pastrana, D. V., Smola, S., Feld, P., Sauter, M., Lohse, S., Ramesh, M., Lim, E. S., Wang, D., Borgogna, C., FitzGerald, P. C., Bliskovsky, V., Starrett, G. J., Law, E. K., Harris, R., Killian, J. K., Zhu, J., Pineda, M., Meltzer, P. S. & 3 othersBoldorini, R., Gariglio, M. & Buck, C. B., May 9 2018, (Accepted/In press) In : Cell Host and Microbe. p. 628-635.e7

Research output: Contribution to journalArticle

BK Virus
Viruses
Kidney
Mutation
Cytosine Deaminase