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Reuben Harris

Professor, College of Biological Sciences, Biochemistry, Molecular Biology, and Biophysics

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

14 Similar Profiles

HIV-1 Medicine & Life Sciences

Cytosine Deaminase Medicine & Life Sciences

DNA Medicine & Life Sciences

Deamination Medicine & Life Sciences

Mutation Medicine & Life Sciences

Cytosine Medicine & Life Sciences

Proteins Medicine & Life Sciences

Mutagenesis Medicine & Life Sciences

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Projects 2005 2021

4 Active
21 Finished

The role of APOBEC3B in breast cancer therapy resistance

KWF KANKER BESTRIJDING

5/1/17 → 4/30/21

Project: Research project

Breast Neoplasms

Therapeutics

APOBEC3 STRUCTURAL STUDIES

Harris, R., Aihara, H., Harki, D. A., Nazarian, S. & Shi, K.

NIH NIGMS NATL INST OF GENERAL

4/15/16 → 2/29/20

Project: Research project

Chemical Interrogation of Human DNA Cytosine Deaminases

Harki, D. A. & Harris, R.

NIH NIGMS NATL INST OF GENERAL

7/1/15 → 4/30/20

Project: Research project

Cytosine Deaminase

DNA

APOBEC3 Proteins in HIV Restriction

NIH Nat'l Inst of Allergy & Infect Dis

1/15/15 → 12/31/19

Project: Research project

Human Immunodeficiency Virus Proteins

Stopping Enzyme-Catalyzed Ovarian Cancer Evolution

MN OVARIAN CANCER ALLIANCE

11/1/16 → 10/31/17

Project: Research project

Ovarian Neoplasms

Enzymes

Research Output 1994 2018

127 Article
16 Review article
5 Chapter
4 Comment/debate
3 More
- 3 Short survey

2 Citations

APOBEC Enzymes as Targets for Virus and Cancer Therapy

Olson, M. E., Harris, R. S. & Harki, D. A. Jan 18 2018 In : Cell Chemical Biology. 25, 1, p. 36-49 14 p.

Research output: Contribution to journal › Review article

Viruses

Mutagenesis

Uracil

Genes

Cytosine

Evaluation of sequence variability in HIV-1 gp41 C-peptide helix-grafted proteins

Tennyson, R. L., Walker, S. N., Ikeda, T., Harris, R. S. & McNaughton, B. R. Mar 15 2018 In : Bioorganic and Medicinal Chemistry. 26, 6, p. 1220-1224 5 p.

Research output: Contribution to journal › Article

C-Peptide

HIV-1

Proteins

HIV Envelope Protein gp41

Peptides

HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G

Ikeda, T., Symeonides, M., Albin, J. S., Li, M., Thali, M. & Harris, R. S. Apr 1 2018 In : PLoS pathogens. 14, 4, e1007010

Research output: Contribution to journal › Article

HIV-1

Homeostasis

Antiviral Agents

Viruses

Product Packaging

Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution

Venkatesan, S., Rosenthal, R., Kanu, N., McGranahan, N., Bartek, J., Quezada, S. A., Hare, J., Harris, R. S. & Swanton, C. Mar 1 2018 In : Annals of Oncology. 29, 3, p. 563-572 10 p.

Research output: Contribution to journal › Review article

Drug Resistance

Mutagenesis

HIV

Virology

Neoplasms

3 Citations

The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism

Shaban, N. M., Shi, K., Lauer, K. V., Carpenter, M. A., Richards, C. M., Salamango, D., Wang, J., Lopresti, M. W., Banerjee, S., Levin-Klein, R., Brown, W. L., Aihara, H. & Harris, R. S. Jan 4 2018 In : Molecular Cell. 69, 1, p. 75-86.e9

Research output: Contribution to journal › Article

Dimerization

Antiviral Agents

HIV-1

RNA

DNA