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  • 15 Similar Profiles
HIV-1 Medicine & Life Sciences
Cytosine Deaminase Medicine & Life Sciences
DNA Medicine & Life Sciences
Deamination Medicine & Life Sciences
Mutation Medicine & Life Sciences
Cytosine Medicine & Life Sciences
Proteins Medicine & Life Sciences
Human immunodeficiency virus 1 Agriculture & Biology

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Projects 2005 2021

Breast Neoplasms
Therapeutics

APOBEC3 STRUCTURAL STUDIES

Harris, R., Aihara, H., Harki, D. A., Nazarian, S. & Shi, K.

NIH NIGMS NATL INST OF GENERAL

4/15/162/29/20

Project: Research project

Human Immunodeficiency Virus Proteins
Ovarian Neoplasms
Enzymes

Research Output 1994 2018

APOBEC3B Nuclear Localization Requires Two Distinct N-Terminal Domain Surfaces

Salamango, D. J., McCann, J. L., Demir, Ö., Brown, W. L., Amaro, R. E. & Harris, R. S., Aug 17 2018, In : Journal of Molecular Biology. 430, 17, p. 2695-2708 14 p.

Research output: Contribution to journalArticle

Cytosine Deaminase
Neoplasms
Uracil
Single-Stranded DNA
Cytosine
4 Citations

APOBEC Enzymes as Targets for Virus and Cancer Therapy

Olson, M. E., Harris, R. S. & Harki, D. A., Jan 18 2018, In : Cell Chemical Biology. 25, 1, p. 36-49 14 p.

Research output: Contribution to journalReview article

Viruses
Mutagenesis
Uracil
Genes
Cytosine

Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution

Peretti, A. , Geoghegan, E. M. , Pastrana, D. V. , Smola, S. , Feld, P. , Sauter, M. , Lohse, S. , Ramesh, M. , Lim, E. S. , Wang, D. , Borgogna, C. , FitzGerald, P. C. , Bliskovsky, V. , Starrett, G. J. , Law, E. K. , Harris, R. S. , Killian, J. K. , Zhu, J. , Pineda, M. , Meltzer, P. S. & 3 others Boldorini, R., Gariglio, M. & Buck, C. B., May 9 2018, (Accepted/In press) In : Cell Host and Microbe. p. 628-635.e7

Research output: Contribution to journalArticle

BK Virus
Viruses
Kidney
Mutation
Cytosine Deaminase

Differential evolution of antiretroviral restriction factors in pteropid bats as revealed by APOBEC3 gene complexity

Hayward, J. A., Tachedjian, M., Cui, J., Cheng, A. Z., Johnson, A., Baker, M. L., Harris, R. S., Wang, L. F. & Tachedjian, G., Jan 1 2018, In : Molecular Biology and Evolution. 35, 7, p. 1626-1637 12 p.

Research output: Contribution to journalArticle

bat
Chiroptera
gene
mammal
Genes

Evaluation of sequence variability in HIV-1 gp41 C-peptide helix-grafted proteins

Tennyson, R. L., Walker, S. N., Ikeda, T., Harris, R. S. & McNaughton, B. R., Mar 15 2018, In : Bioorganic and Medicinal Chemistry. 26, 6, p. 1220-1224 5 p.

Research output: Contribution to journalArticle

C-Peptide
HIV-1
Proteins
HIV Envelope Protein gp41
Peptides