1983 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2019

Isolation of mouse epidermal keratinocytes and their in vitro clonogenic culture

Morris, R. J., Readio, N., Boland, K., Johnson, K., Lad, S., Singh, A., Singh, A., Holtorf, S. & Skaar, S., Aug 2019, In : Journal of Visualized Experiments. 2019, 150, e58701.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms

Park, H., Lad, S., Boland, K., Johnson, K., Readio, N., Jin, G., Asfaha, S., Patterson, K. S., Singh, A., Yang, X., Londono, D., Singh, A., Trempus, C., Gordon, D., Wang, T. C. & Morris, R. J., Dec 1 2018, In : Nature Communications. 9, 1, 5293.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Epidermal FABP Prevents Chemical-Induced Skin Tumorigenesis by Regulation of TPA-Induced IFN/p53/SOX2 Pathway in Keratinocytes

Zhang, Y., Hao, J., Zeng, J., Li, Q., Rao, E., Sun, Y., Liu, L., Mandal, A., Landers, V. D., Morris, R. J., Cleary, M. P., Suttles, J. & Li, B., Sep 2018, In : Journal of Investigative Dermatology. 138, 9, p. 1925-1934 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2017

Hmga2 translocation induced in skin tumorigenesis

Li, Y., Pi, X. Y., Boland, K., Lad, S., Johnson, K., Verfaillie, C. & Morris, R. J., 2017, In : Oncotarget. 8, 18, p. 30019-30029 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2015

Epidermal Fatty Acid Binding Protein Promotes Skin Inflammation Induced by High-Fat Diet

Zhang, Y., Li, Q., Rao, E., Sun, Y., Grossmann, M. E., Morris, R. J., Cleary, M. P. & Li, B., May 19 2015, In : Immunity. 42, 5, p. 953-964 12 p.

Research output: Contribution to journalArticle

47 Scopus citations
2014

The ex vivo use of keratinocytes from adult mice to define stem cell activities in cancer research

Morris, R. J., Readio, N., Johnson, K. M., Singh, A., Park, H., Singh, A. & Schuster, T. F., Jan 13 2014, Cancer Prevention: Dietary Factors and Pharmacology. Bode, A. M. & Dong, Z. (eds.). p. 205-236 32 p. (Methods in Pharmacology and Toxicology).

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse

Li, S., Park, H., Trempus, C. S., Gordon, D., Liu, Y., Cotsarelis, G. & Morris, R. J., Oct 1 2013, In : Molecular Carcinogenesis. 52, 10, p. 751-759 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
2012

CD133 in the selection of epidermal stem cells in mice: Steps in the right direction

Nordvig, A. S., Owens, D. M. & Morris, R. J., Nov 2012, In : Journal of Investigative Dermatology. 132, 11, p. 2492-2494 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Expression of kruppel-like factor KLF4 in mouse hair follicle stem cells contributes to cutaneous wound healing

Li, J., Zheng, H., Wang, J., Yu, F., Morris, R. J., Wang, T. C., Huang, S. & Ai, W., Jun 20 2012, In : PloS one. 7, 6, e39663.

Research output: Contribution to journalArticle

17 Scopus citations

Innate immunity and the regulation and mobilization of keratinocyte stem cells: Are the old players playing a new game?

Singh, A. & Morris, R. J., Sep 1 2012, In : Experimental Dermatology. 21, 9, p. 660-664 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Keratinocyte stem cells and the targets for nonmelanoma skin cancer

Singh, A., Park, H., Kangsamaksin, T., Singh, A., Readio, N. & Morris, R. J., Sep 1 2012, In : Photochemistry and Photobiology. 88, 5, p. 1099-1110 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development

Hayes, C. S., DeFeo, K., Dang, H., Trempus, C. S., Morris, R. J. & Gilmour, S. K., Sep 9 2011, In : Carcinogenesis. 32, 9, p. 1340-1348 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Bone morphogenetic protein 5 regulates the number of keratinocyte stem cells from the skin of mice

Kangsamaksin, T. & Morris, R. J., Mar 2011, In : Journal of Investigative Dermatology. 131, 3, p. 580-585 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2010

Stem cells in chemical carcinogenesis

Dietrich, C., Weiss, C., Bockamp, E., Brisken, C., Roskams, T., Morris, R., Oesch-Bartlomowicz, B. & Oesch, F., Mar 1 2010, In : Archives of Toxicology. 84, 3, p. 245-251 7 p.

Research output: Contribution to journalArticle

The Yin and Yang of bone morphogenetic proteins in cancer

Singh, A. & Morris, R. J., Aug 1 2010, In : Cytokine and Growth Factor Reviews. 21, 4, p. 299-313 15 p.

Research output: Contribution to journalReview article

63 Scopus citations
2007

A perspective on murine keratinocyte stem cells as targets of chemically induced skin cancer

Kangsamaksin, T., Heui, J. P., Trempus, C. S. & Morris, R. J., Aug 1 2007, In : Molecular Carcinogenesis. 46, 8, p. 579-584 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

CD34 expression by hair follicle stem cells is required for skin tumor development in mice

Trempus, C. S., Morris, R. J., Ehinger, M., Elmore, A., Bortner, C. D., Ito, M., Cotsarelis, G., Nijhof, J. G. W., Peckham, J., Flagler, N., Kissling, G., Humble, M. M., King, L. C., Adams, L. D., Desai, D., Amin, S. & Tennant, R. W., May 1 2007, In : Cancer Research. 67, 9, p. 4173-4181 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

Comprehensive microarray transcriptome profiling of CD34-enriched mouse keratinocyte stem cells [2]

Trempus, C. S., Dang, H., Humble, M. M., Wei, S. J., Gerdes, M. J., Morris, R. J., Bortner, C. D., Cotsarelis, G. & Tennant, R. W., Dec 2007, In : Journal of Investigative Dermatology. 127, 12, p. 2904-2907 4 p.

Research output: Contribution to journalLetter

17 Scopus citations
2 Scopus citations
2006

A perspective on in vitro clonogenic keratinocytes: A window into the regulation of the progenitor cell compartment of the cutaneous epithelium

Morris, R. J., Jan 1 2006, Tissue Stem Cells. CRC Press, p. 149-160 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Erratum: Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis (Nature Medicine (2005) 11 (1351-1354))

Ito, M., Liu, Y., Yang, Z., Nguyen, J., Liang, F., Morris, R. J. & Cotsarelis, G., Jan 1 2006, In : Nature Medicine. 12, 1, 1 p.

Research output: Contribution to journalComment/debate

Identification of genes and gene ontology processes critical to skin papilloma development in Tg.AC transgenic mice

Dang, H., Trempus, C., Malarkey, D. E., Wei, S. J., Humble, M., Morris, R. J. & Tennant, R. W., Feb 1 2006, In : Molecular Carcinogenesis. 45, 2, p. 126-140 15 p.

Research output: Contribution to journalArticle

6 Scopus citations
2005

In vivo labeling and analysis of epidermal stem cells.

Wu, W. Y. & Morris, R. J., 2005, In : Methods in molecular biology (Clifton, N.J.). 289, p. 73-78 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
24 Scopus citations

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

Ito, M., Liu, Y., Yang, Z., Nguyen, J., Liang, F., Morris, R. J. & Cotsarelis, G., Dec 1 2005, In : Nature Medicine. 11, 12, p. 1351-1354 4 p.

Research output: Contribution to journalArticle

862 Scopus citations
2004

A perspective on keratinocyte stem cells as targets for skin carcinogenesis

Morris, R. J., Oct 2004, In : Differentiation. 72, 8, p. 381-386 6 p.

Research output: Contribution to journalReview article

40 Scopus citations

Capturing and profiling adult hair follicle stem cells

Morris, R. J., Liu, Y., Marles, L., Yang, Z., Trempus, C., Li, S., Lin, J. S., Sawicki, J. A. & Cotsarelis, G., Apr 1 2004, In : Nature biotechnology. 22, 4, p. 411-417 7 p.

Research output: Contribution to journalArticle

969 Scopus citations

Independent inheritance of genes regulating two subpopulations of mouse clonogenic keratinocyte stem cells

Popova, N. V., Suleimanian, N. E., Stepanova, E. A., Teti, K. A., Wu, K. Q. & Morris, R. J., Sep 2004, In : Journal of Investigative Dermatology Symposium Proceedings. 9, 3, p. 253-260 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2003

CD34 in Human Hair Follicle [2] (multiple letters)

Poblet, E., Jiménez, F., Trempus, C. S., Morris, R. J., Cotsarelis, G. & Tennant, R. W., Nov 2003, In : Journal of Investigative Dermatology. 121, 5, p. 1220-1221 2 p.

Research output: Contribution to journalLetter

5 Scopus citations

Desmoglein 4 in hair follicle differentiation and epidermal adhesion: Evidence from inherited hypotrichosis and acquired pemphigus vulgaris

Kljuic, A., Bazzi, H., Sundberg, J. P., Martinez-Mir, A., O'Shaughnessy, R., Mahoney, M. G., Levy, M., Montagutelli, X., Ahmad, W., Aita, V. M., Gordon, D., Uitto, J., Whiting, D., Ott, J., Fischer, S., Gilliam, T. C., Jahoda, C. A. B., Morris, R. J., Panteleyev, A. A., Nguyen, V. T. & 1 others, Christiano, A. M., Apr 18 2003, In : Cell. 113, 2, p. 249-260 12 p.

Research output: Contribution to journalArticle

251 Scopus citations

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34

Trempus, C. S., Morris, R. J., Bortner, C. D., Cotsarelis, G., Faircloth, R. S., Reece, J. M. & Tennant, R. W., Apr 1 2003, In : Journal of Investigative Dermatology. 120, 4, p. 501-511 11 p.

Research output: Contribution to journalArticle

454 Scopus citations

Genetic regulation of mouse stem cells: Identification of two keratinocyte stem cell regulatory loci

Popova, N. V. & Morris, R. J., Oct 1 2003, In : Current Topics in Microbiology and Immunology. 280, p. 111-137 27 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of two keratinocyte stem cell regulatory loci implicated in skin carcinogenesis

Popova, N. V., Teti, K. A., Wu, K. Q. & Morris, R. J., Mar 1 2003, In : Carcinogenesis. 24, 3, p. 417-425 9 p.

Research output: Contribution to journalReview article

15 Scopus citations
2002

Evidence that the keratinocyte colony number is genetically controlled

Popova, N. V., Tryson, K. A., Wu, K. Q. & Morris, R. J., Dec 1 2002, In : Experimental Dermatology. 11, 6, p. 503-508 6 p.

Research output: Contribution to journalArticle

13 Scopus citations
2001

Age-dependent skin tumorigenesis and transgene expression in the Tg.AC (v-Ha-ras) transgenic mouse

Battalora, M. S. J., Spalding, J. W., Szczesniak, C. J., Cape, J. E., Morris, R. J., Trempus, C. S., Bortner, C. D., Lee, B. M. & Tennant, R. W., Jan 1 2001, In : Carcinogenesis. 22, 4, p. 651-659 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2000

Both (±)syn- and (±)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at codon 61 of c-H-ras1

Tang, M. S., Vulimiri, S. V., Viaje, A., Chen, J. X., Bilolikar, D. S., Morris, R. J., Harvey, R. G., Slaga, T. J. & DiGiovanni, J., Oct 15 2000, In : Cancer Research. 60, 20, p. 5688-5695 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Enrichment for murine keratinocyte stem cells based on cell surface phenotype

Tani, H., Morris, R. J. & Kaur, P., Sep 26 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 20, p. 10960-10965 6 p.

Research output: Contribution to journalArticle

330 Scopus citations

Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis or infundibulum as well as in the hair follicles

Morris, R. J., Tryson, K. A. & Wu, K. Q., Jan 15 2000, In : Cancer Research. 60, 2, p. 226-229 4 p.

Research output: Contribution to journalArticle

87 Scopus citations

Keratinocyte stem cells: Targets for cutaneous carcinogens

Morris, R. J., Jul 2000, In : Journal of Clinical Investigation. 106, 1, p. 3-8 6 p.

Research output: Contribution to journalReview article

83 Scopus citations
1999

Highly persistent label-retaining cells in the hair follicles of mice and their fate following induction of anagen

Morris, R. J. & Potten, C. S., Jan 1 1999, In : Journal of Investigative Dermatology. 112, 4, p. 470-475 6 p.

Research output: Contribution to journalArticle

223 Scopus citations
1998

A composite CMV-IE enhancer/β-actin promoter is ubiquitously expressed in mouse cutaneous epithelium

Sawicki, J. A., Morris, R. J., Monks, B., Sakai, K. & Miyazaki, J. I., Oct 10 1998, In : Experimental Cell Research. 244, 1, p. 367-369 3 p.

Research output: Contribution to journalArticle

62 Scopus citations

Cell-specific ecdysone-inducible expression of FLP recombinase in mammalian cells

Sawicki, J. A., Monks, B. & Morris, R. J., 1998, In : BioTechniques. 25, 5, p. 868-875 8 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations
1997

Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling

Morris, R. J., Coulter, K., Tryson, K. & Steinberg, S. R., Aug 15 1997, In : Cancer Research. 57, 16, p. 3436-3443 8 p.

Research output: Contribution to journalArticle

77 Scopus citations

Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms

Zhang, S. Y., Liu, S. C., Goodrow, T., Morris, R. & Klein-Szanto, A. J. P., Mar 1 1997, In : Molecular Carcinogenesis. 18, 3, p. 142-152 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Ornithine decarboxylase overexpression leads to increased epithelial tumor invasiveness

Smith, M. K., Goral, M. A., Wright, J. H., Matrisian, L. M., Morris, R. J., Klein-Szanto, A. J. P. & Gilmour, S. K., Jun 1 1997, In : Cancer Research. 57, 11, p. 2104-2108 5 p.

Research output: Contribution to journalArticle

45 Scopus citations
1996

Sequence preference of 7,12-dimethylbenz[a]anthracene-syn-diol epoxide- DNA binding in the mouse H-ras gene detected by UvrABC nucleases

Chen, J. X., Pao, A., Zheng, Y., Ye, X., Kisleyou, A. S., Morris, R. J., Slaga, T. J., Harvey, R. G. & Tang, M. S., Oct 4 1996, In : Biochemistry. 35, 29, p. 9594-9602 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Using UvrABC nuclease to detect 7,12-dimethylbenz[a]anthracene anti- diol epoxide-DNA binding specificity in the mouse H-ras gene

Chen, J. X., Kisleyou, A. S., Harvey, R. G., Slaga, T. J., Morris, R. J. & Tang, M. S., Dec 14 1996, In : Chemical research in toxicology. 9, 8, p. 1350-1354 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
1994

Slowly cycling (label‐retaining) epidermal cells behave like clonogenic stem cells in vitro

Morris, R. J. & Potten, C. S., May 1994, In : Cell Proliferation. 27, 5, p. 279-289 11 p.

Research output: Contribution to journalArticle

185 Scopus citations
1993

Association of protein kinase C activation with induction of ornithine decarboxylase in murine but not human keratinocyte cultures

Fischer, S. M., Lee, M. L., Maldve, R. E., Morris, R. J., Trono, D., Burow, D. L., Butler, A. P., Pavone, A. & Warren, B., 1993, In : Molecular Carcinogenesis. 7, 4, p. 228-237 10 p.

Research output: Contribution to journalArticle

32 Scopus citations